Brian O. Diekman, Ph.D.

2012 Biomedical Engineering Duke University, Durham, NC 
Biomedical, General, Biomechanics
"Brian Diekman"


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Farshid Guilak grad student 2012 Duke
 (Stem Cell-Based Strategies to Study, Prevent, and Treat Cartilage Injury and Osteoarthritis.)
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Collins JA, Kapustina M, Bolduc JA, et al. (2021) Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes. Free Radical Biology & Medicine
Griffith CM, Huang SA, Cho C, et al. (2020) Microfluidics for the study of mechanotransduction. Journal of Physics D: Applied Physics. 53
Loeser RF, Collins JA, Diekman BO, et al. (2020) Reply. Arthritis & Rheumatology (Hoboken, N.J.). 72: 2162-2163
Copp ME, Flanders MC, Gagliardi R, et al. (2020) The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence. Osteoarthritis and Cartilage
Coryell PR, Diekman BO, Loeser RF. (2020) Mechanisms and therapeutic implications of cellular senescence in osteoarthritis. Nature Reviews. Rheumatology
Loeser RF, Kelley KL, Armstrong A, et al. (2020) Deletion of c-Jun N-terminal Kinase Enhances Senescence in Joint Tissues and Increases the Severity of Age-Related Osteoarthritis in Mice. Arthritis & Rheumatology (Hoboken, N.J.)
Tessier S, Doolittle AC, Sao K, et al. (2020) Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight
Diekman BO. (2020) Dynamic interplay between connective tissues and the surrounding environment during aging Connective Tissue Research. 61: 1-3
D'Costa S, Rich MJ, Diekman BO. (2019) Engineered cartilage from human chondrocytes with homozygous knockout of cell cycle inhibitor p21. Tissue Engineering. Part A
Sessions GA, Copp ME, Liu JY, et al. (2019) Controlled induction and targeted elimination of p16-expressing chondrocytes in cartilage explant culture. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900815RR
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