Samuel C. Nalle, Ph.D.
Affiliations: | 2011 | Pathology | University of Chicago, Chicago, IL |
Area:
ImmunologyGoogle:
"Samuel Nalle"Parents
Sign in to add mentor| Jerrold R. Turner | grad student | 2011 | Chicago | |
| (Intestinal damage and tight junction dysfunction are essential for minor mismatch graft-versus-host disease.) | ||||
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Publications
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| Nalle SC, Zuo L, Ong MLDM, et al. (2019) Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. The Journal of Clinical Investigation |
| Nalle SC, Turner JR. (2015) Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. Mucosal Immunology. 8: 720-30 |
| Nalle SC, Kwak HA, Edelblum KL, et al. (2014) Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Science Translational Medicine. 6: 243ra87 |
| Su L, Nalle SC, Shen L, et al. (2013) TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis. Gastroenterology. 145: 407-15 |
| Nalle SC, Turner JR. (2012) Endothelial and epithelial barriers in graft-versus-host disease. Advances in Experimental Medicine and Biology. 763: 105-31 |
| Tang X, Nalle SC, Shen L, et al. (2011) Knock-Down of Irbit (Inositol-1,4,5-Trisphosphate Receptor Binding Protein Released With IP3) Increases Epithelial Paracellular Permeability Gastroenterology. 140: S-503 |
| Nalle SC, Joseph NE, Savage PA, et al. (2011) Intestinal Damage and Myosin Light Chain Kinase (MLCK)-Dependent Epithelial Barrier Dysfunction Are Vital to Minor Mismatch Graft-Versus-Host Disease Gastroenterology. 140: S-167 |
| Nalle SC, Savage PA, Turner JR. (2010) Total Body Irradiation Creates a Proinflammatory Milieu That Is Required for Minor, but Not Major, Mismatch Graft-Versus-Host-Disease. Blood. 116: 3736-3736 |
| Nalle SC, Turner JR. (2009) Menetrier's disease therapy: rebooting mucosal signaling. Science Translational Medicine. 1: 8ps10 |
| Nalle SC, Turner JR. (2009) Epithelium, tear down this wall! Cell Host & Microbe. 5: 1-2 |