Keith F. Decker, Ph.D.

Affiliations: 
2010 Biomedical Engineering Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical Engineering, Physiology Biology
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"Keith Decker"

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Yoram Rudy grad student 2010 Washington University
 (Ionic mechanisms of action potential rate dependence, conduction and block in normal epicardium and in remodeled epicardium post-infarction.)
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Publications

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Powell E, Shao J, Yuan Y, et al. (2016) p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Research : Bcr. 18: 13
Vanderkraats ND, Hiken JF, Decker KF, et al. (2013) Discovering high-resolution patterns of differential DNA methylation that correlate with gene expression changes. Nucleic Acids Research. 41: 6816-27
Jeyaraj D, Wan X, Ficker E, et al. (2013) Ionic bases for electrical remodeling of the canine cardiac ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 305: H410-9
Chen Y, Decker KF, Zheng D, et al. (2013) A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor κB (NFκB)-mediated cardiac transcription. The Journal of Biological Chemistry. 288: 15455-65
Zheng D, Decker KF, Zhou T, et al. (2013) Role of WNT7B-induced noncanonical pathway in advanced prostate cancer. Molecular Cancer Research : McR. 11: 482-93
Decker KF, Zheng D, He Y, et al. (2012) Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions. Nucleic Acids Research. 40: 10765-79
Decker KF, Rudy Y. (2010) Ionic mechanisms of electrophysiological heterogeneity and conduction block in the infarct border zone. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1588-97
Silva JR, Pan H, Wu D, et al. (2009) A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential. Proceedings of the National Academy of Sciences of the United States of America. 106: 11102-6
Decker KF, Heijman J, Silva JR, et al. (2009) Properties and ionic mechanisms of action potential adaptation, restitution, and accommodation in canine epicardium. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1017-26
Hund TJ, Decker KF, Kanter E, et al. (2008) Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling. Journal of Molecular and Cellular Cardiology. 45: 420-8
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