Joan S. Brugge

Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Cell Biology, General Biophysics, Biomechanics Biophysics
"Joan Brugge"


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Bridget N. Queenan research assistant 2003 Harvard Medical School (Neurotree)
Maria A. Martinez Gakidis grad student 2003 Harvard
Kenna R. Mills grad student 2004 Harvard
Sarah E. Seton-Rogers grad student 2004 Harvard
Nicole L. Collins grad student 2006 Harvard
Melodie L. Knowlton grad student 2010 Harvard
Alexandra R. Grassian grad student 2011 Harvard
Alice S. Kaanta grad student 2012 Harvard
Mei R. Ng grad student 2012 Harvard
Rachel A. Davidowitz grad student 2013 Harvard
Zachary T. Schafer post-doc Harvard (Chemistry Tree)
Shengwen Li post-doc 1997-1998 Harvard University (medical School) (Chemistry Tree)
Mauricio J. Reginato post-doc 1998-2004 Harvard Medical School (Cell Biology Tree)
Jonathan A. kelber research scientist 2017-2017 Harvard Medical School (Neurotree)
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Zoeller JJ, Press MF, Selfors LM, et al. (2021) Clinical evaluation of BCL-2/XL levels pre- and post- HER2-targeted therapy. Plos One. 16: e0251163
Li CM, Shapiro H, Tsiobikas C, et al. (2020) Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing. Cell Reports. 33: 108566
Naffar-Abu Amara S, Kuiken HJ, Selfors LM, et al. (2020) Transient commensal clonal interactions can drive tumor metastasis. Nature Communications. 11: 5799
Zhao W, Li J, Chen MM, et al. (2020) Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. Cancer Cell
Takahashi N, Cho P, Selfors LM, et al. (2020) 3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis. Molecular Cell
Zervantonakis IK, Poskus MD, Scott AL, et al. (2020) Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways. Proceedings of the National Academy of Sciences of the United States of America
Rosenbluth JM, Schackmann RCJ, Gray GK, et al. (2020) Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications. 11: 1711
Iavarone C, Zervantonakis IK, Selfors LM, et al. (2019) Combined MEK and BCL-2/XL inhibition is effective in high-grade serous ovarian cancer patient-derived xenograft models and BIM levels are predictive of responsiveness. Molecular Cancer Therapeutics
Zoeller JJ, Hurvitz SA, Press MF, et al. (2019) Abstract 2978: Clinical evaluation of lapatinib induced BCL-2 adaptive responses Cancer Research. 79: 2978-2978
Cho P, Takahashi N, Selfors LM, et al. (2019) Abstract 884: Interplay between NRF2 and GPX4 is critical for cancer cell survival in 3D spheroids Cancer Research. 79: 884-884
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