Marilyn Farquhar

Affiliations: 
Cellular and Molecular Medicine University of California, San Diego, La Jolla, CA 
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"Marilyn Farquhar"
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Children

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John P. Caulfield grad student Harvard Medical School
Katherine A. Rader grad student 2000 UCSD
Eric Elenko grad student 2001 UCSD
Emily I. Chen grad student 2002 UCSD
Xiaojing Lou grad student 2002 UCSD
Bin Zheng grad student 2002 UCSD
Jason A. Hoffman grad student 2003 UCSD
Scott J. Bornheimer grad student 2008 UCSD (Biomechanics Tree)
Anthony O. Beas grad student 2009 UCSD
Tingdong Tang grad student 2009 UCSD
Volker Herzog post-doc UCSD
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Publications

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Gupta V, Bhandari D, Leyme A, et al. (2016) GIV/Girdin activates Gαi and inhibits Gαs via the same motif. Proceedings of the National Academy of Sciences of the United States of America
Bhandari D, Lopez-Sanchez I, To A, et al. (2015) Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy. Proceedings of the National Academy of Sciences of the United States of America. 112: E4874-83
Lo IC, Gupta V, Midde KK, et al. (2015) Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling. Developmental Cell. 33: 189-203
Garcia-Marcos M, Ghosh P, Farquhar MG. (2015) GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation. The Journal of Biological Chemistry. 290: 6697-704
López-Sánchez I, Garcia-Marcos M, Mittal Y, et al. (2013) Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin. Proceedings of the National Academy of Sciences of the United States of America. 110: 5510-5
Varsano T, Taupin V, Guo L, et al. (2012) The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA. Plos One. 7: e49227
Beas AO, Taupin V, Teodorof C, et al. (2012) Gαs promotes EEA1 endosome maturation and shuts down proliferative signaling through interaction with GIV (Girdin). Molecular Biology of the Cell. 23: 4623-34
Garcia-Marcos M, Kietrsunthorn PS, Pavlova Y, et al. (2012) Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 1961-6
Ghosh P, Garcia-Marcos M, Farquhar MG. (2011) GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression. Cell Adhesion & Migration. 5: 237-48
Garcia-Marcos M, Ear J, Farquhar MG, et al. (2011) A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals. Molecular Biology of the Cell. 22: 673-86
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