Ching-Shih Chen

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Biochemistry
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"Ching-Shih Chen"
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Publications

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Chang WL, Hsu LC, Leu WJ, et al. (2015) Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - a crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation. Oncotarget
Liu TM, Ling Y, Woyach JA, et al. (2015) OSU-T315: a novel targeted therapeutic that antagonizes AKT membrane localization and activation of chronic lymphocytic leukemia cells. Blood. 125: 284-95
Lee SL, Chou CC, Chuang HC, et al. (2013) Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines. Plos One. 8: e67149
Ma Y, McCarty SK, Kapuriya NP, et al. (2013) Development of p21 activated kinase-targeted multikinase inhibitors that inhibit thyroid cancer cell migration. The Journal of Clinical Endocrinology and Metabolism. 98: E1314-22
Yang YL, Huang PH, Chiu HC, et al. (2013) Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism. Biochemical and Biophysical Research Communications. 435: 107-12
Liu T, Ling Y, Phelps MA, et al. (2013) OSU-T315, An Integrin-Linked Kinase (ILK) Inhibitor, Induces Apoptosis By Targeting B Cell Receptor and CD49d Mediated AKT/ERK Activation In Chronic Lymphocytic Leukemia Cells Blood. 122: 2523-2523
Bai LY, Ma Y, Kulp SK, et al. (2011) OSU-DY7, a novel D-tyrosinol derivative, mediates cytotoxicity in chronic lymphocytic leukaemia and Burkitt lymphoma through p38 mitogen-activated protein kinase pathway. British Journal of Haematology. 153: 623-33
Ching TT, Chiang WC, Chen CS, et al. (2011) Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. Aging Cell. 10: 506-19
Mani R, Frissora FW, Chen C, et al. (2011) OSU-2S, A Novel FTY720 derivative, Mediates Cytotoxicity In Chronic Lymphocytic Leukemia Through PKC Dependent Modulation of SHP1 Tyrosine Phosphatase Blood. 118: 2499-2499
Oaks JJ, Mukhopadhyay A, Santhanam R, et al. (2010) Pharmacologic Restoration of PP2A Activity and Interference with the SET-PP2A Interplay by FTY720 and Its Non-Immunosuppressive Derivative as a Novel and Efficient Therapy for Ph-Negative Myeloproliferative Disorders Blood. 116: 775-775
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