Aleksander S. Popel

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Biomedical Engineering, Molecular Biology, General Biophysics
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"Aleksander Popel"
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Children

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Esak Lee grad student (Biomechanics Tree)
Feilim Mac Gabhann grad student 2007 Johns Hopkins
Emmanouil D. Karagiannis grad student 2008 Johns Hopkins
Jacob E. Koskimaki grad student 2012 Johns Hopkins
Richard J Sove post-doc Johns Hopkins (Econometree)
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Publications

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Sargunas PR, Ariail E, Lima E Silva R, et al. (2025) Bispecific receptor decoy proteins inhibit ocular neovascularization via simultaneous blockade of vascular endothelial growth factor A and C. Molecular Therapy : the Journal of the American Society of Gene Therapy
Furukawa N, Yang W, Chao AR, et al. (2024) Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth. Cell Death Discovery. 10: 161
Furukawa N, Yang W, Chao A, et al. (2023) Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth. Research Square
Zhang Y, Popel AS, Bazzazi H. (2023) Combining Multikinase Tyrosine Kinase Inhibitors Targeting the Vascular Endothelial Growth Factor and Cluster of Differentiation 47 Signaling Pathways Is Predicted to Increase the Efficacy of Antiangiogenic Combination Therapies. Acs Pharmacology & Translational Science. 6: 710-726
Lima E Silva R, Mirando AC, Tzeng SY, et al. (2023) Anti-angiogenic collagen IV-derived peptide target engagement with αβ and αβ in ocular neovascularization models. Iscience. 26: 106078
Sové RJ, Verma BK, Wang H, et al. (2022) Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model. Journal For Immunotherapy of Cancer. 10
Ruiz-Martinez A, Gong C, Wang H, et al. (2022) Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model. Plos Computational Biology. 18: e1010254
Zhao C, Medeiros TX, Sové RJ, et al. (2021) A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization. Iscience. 24: 102112
Wang H, Ma H, Sové RJ, et al. (2021) Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer. Journal For Immunotherapy of Cancer. 9
Mirando AC, Patil A, Rafie CI, et al. (2020) Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 9: 1760685
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