Parents
Sign in to add mentor| Eric Leclerc | grad student | 2010 | Compiègne (BME Tree) | |
| (Validation d'un microsystème hépatique dédié aux études pharmaco-toxicologiques) | ||||
| Cécile Legallais | grad student | 2010 | Compiègne | |
| (Validation d'un microsystème hépatique dédié aux études pharmaco-toxicologiques) | ||||
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Publications
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| Stancescu M, Molnar P, McAleer CW, et al. (2015) A phenotypic in vitro model for the main determinants of human whole heart function. Biomaterials. 60: 20-30 |
| Esch MB, Prot JM, Wang YI, et al. (2015) Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow. Lab On a Chip. 15: 2269-77 |
| Prot JM, Maciel L, Bricks T, et al. (2014) First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans. Biotechnology and Bioengineering. 111: 2027-40 |
| Smith AS, Long CJ, Berry BJ, et al. (2013) Microphysiological systems and low-cost microfluidic platform with analytics. Stem Cell Research & Therapy. 4: S9 |
| Baudoin R, Prot JM, Nicolas G, et al. (2013) Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 140-52 |
| Ouattara DA, Prot JM, Bunescu A, et al. (2012) Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells. Molecular Biosystems. 8: 1908-20 |
| Cheng S, Prot JM, Leclerc E, et al. (2012) Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions. Bmc Genomics. 13: 54 |
| Shintu L, Baudoin R, Navratil V, et al. (2012) Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs. Analytical Chemistry. 84: 1840-8 |
| Prot JM, Bunescu A, Elena-Herrmann B, et al. (2012) Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury. Toxicology and Applied Pharmacology. 259: 270-80 |
| Prot JM, Leclerc E. (2012) The current status of alternatives to animal testing and predictive toxicology methods using liver microfluidic biochips. Annals of Biomedical Engineering. 40: 1228-43 |