Year |
Citation |
Score |
2023 |
Lee V, Rodriguez DM, Ganci NK, Zeng S, Ai J, Chao JL, Walker MT, Miller CH, Klawon DEJ, Schoenbach MH, Kennedy DE, Maienschein-Cline M, Socci ND, Clark MR, Savage PA. The endogenous repertoire harbors self-reactive CD4 T cell clones that adopt a follicular helper T cell-like phenotype at steady state. Nature Immunology. PMID 36759711 DOI: 10.1038/s41590-023-01425-0 |
0.528 |
|
2021 |
Chao JL, Korzinkin M, Zhavoronkov A, Ozerov IV, Walker MT, Higgins K, Lingen MW, Izumchenko E, Savage PA. Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma. Cell Reports. Medicine. 2: 100399. PMID 34622236 DOI: 10.1016/j.xcrm.2021.100399 |
0.528 |
|
2021 |
Wong HS, Park K, Gola A, Baptista AP, Miller CH, Deep D, Lou M, Boyd LF, Rudensky AY, Savage PA, Altan-Bonnet G, Tsang JS, Germain RN. A local regulatory T cell feedback circuit maintains immune homeostasis by pruning self-activated T cells. Cell. PMID 34157301 DOI: 10.1016/j.cell.2021.05.028 |
0.457 |
|
2021 |
Klawon DEJ, Gilmore DC, Leonard JD, Miller CH, Chao JL, Walker MT, Duncombe RK, Tung KS, Adams EJ, Savage PA. Altered selection on a single self-ligand promotes susceptibility to organ-specific T cell infiltration. The Journal of Experimental Medicine. 218. PMID 33914024 DOI: 10.1084/jem.20200701 |
0.447 |
|
2020 |
Miller CH, Klawon DEJ, Zeng S, Lee V, Socci ND, Savage PA. Eomes identifies thymic precursors of self-specific memory-phenotype CD8 T cells. Nature Immunology. PMID 32284593 DOI: 10.1038/S41590-020-0653-1 |
0.486 |
|
2020 |
Savage PA, Klawon DEJ, Miller CH. Regulatory T Cell Development. Annual Review of Immunology. PMID 31990619 DOI: 10.1146/Annurev-Immunol-100219-020937 |
0.537 |
|
2019 |
Saloura V, Izumchenko E, Zuo Z, Bao R, Korzinkin M, Ozerov I, Zhavoronkov A, Sidransky D, Bedi A, Hoque MO, Koeppen H, Keck MK, Khattri A, London N, Kotlov N, ... ... Savage PA, et al. Immune profiles in primary squamous cell carcinoma of the head and neck. Oral Oncology. 96: 77-88. PMID 31422218 DOI: 10.1016/J.Oraloncology.2019.06.032 |
0.43 |
|
2019 |
MacNabb BW, Kline DE, Albright AR, Chen X, Leventhal DS, Savage PA, Kline J. Negligible Role for Deletion Mediated by cDC1 in CD8 T Cell Tolerance. Journal of Immunology (Baltimore, Md. : 1950). PMID 30902900 DOI: 10.4049/Jimmunol.1801621 |
0.521 |
|
2019 |
Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. The Journal of Clinical Investigation. PMID 30667372 DOI: 10.1172/Jci98554 |
0.381 |
|
2019 |
Chao JL, Savage PA. Abstract A177: Impact of regulatory T-cells on carcinogenesis of oral squamous cell carcinoma Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A177 |
0.51 |
|
2018 |
Chao JL, Savage PA. Unlocking the Complexities of Tumor-Associated Regulatory T Cells. Journal of Immunology (Baltimore, Md. : 1950). 200: 415-421. PMID 29311383 DOI: 10.4049/Jimmunol.1701188 |
0.554 |
|
2017 |
Leonard JD, Gilmore DC, Dileepan T, Nawrocka WI, Chao JL, Schoenbach MH, Jenkins MK, Adams EJ, Savage PA. Identification of Natural Regulatory T Cell Epitopes Reveals Convergence on a Dominant Autoantigen. Immunity. PMID 28709804 DOI: 10.1016/J.Immuni.2017.06.015 |
0.515 |
|
2017 |
Seiwert TY, Bao R, Tan YC, Acharya R, Brisson RJ, Kochanny S, Arshad S, Zuo Z, Saloura V, Agrawal N, Gooi Z, Blair EA, Lingen MW, Vokes EE, Gajewski T, ... Savage PA, et al. Correlation of constitutive PD-1 resistance in HNC with GM-CSF expression and presence of myeloid derived suppressor cells (MDSCs). Journal of Clinical Oncology. 35: 6049-6049. DOI: 10.1200/Jco.2017.35.15_Suppl.6049 |
0.344 |
|
2016 |
Malchow S, Leventhal DS, Lee V, Nishi S, Socci ND, Savage PA. Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage. Immunity. PMID 27130899 DOI: 10.1016/J.Immuni.2016.02.009 |
0.561 |
|
2016 |
Leventhal DS, Gilmore DC, Berger JM, Nishi S, Lee V, Malchow S, Kline DE, Kline J, Vander Griend DJ, Huang H, Socci ND, Savage PA. Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells. Immunity. PMID 27037189 DOI: 10.1016/J.Immuni.2016.01.025 |
0.515 |
|
2015 |
Lee V, Savage PA. Close Encounters of the Tertiary Kind. Immunity. 43: 418-20. PMID 26377895 DOI: 10.1016/J.Immuni.2015.08.022 |
0.533 |
|
2014 |
Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Science Translational Medicine. 6: 243ra87. PMID 24990882 DOI: 10.1126/Scitranslmed.3008941 |
0.386 |
|
2014 |
Chen X, Fosco D, Kline DE, Meng L, Nishi S, Savage PA, Kline J. PD-1 regulates extrathymic regulatory T-cell differentiation. European Journal of Immunology. 44: 2603-16. PMID 24975127 DOI: 10.1002/Eji.201344423 |
0.363 |
|
2014 |
Savage PA, Leventhal DS, Malchow S. Shaping the repertoire of tumor-infiltrating effector and regulatory T cells. Immunological Reviews. 259: 245-58. PMID 24712470 DOI: 10.1111/Imr.12166 |
0.563 |
|
2014 |
Savage PA. Tumor antigenicity revealed. Trends in Immunology. 35: 47-8. PMID 24439426 DOI: 10.1016/J.It.2014.01.001 |
0.326 |
|
2013 |
Malchow S, Leventhal DS, Nishi S, Fischer BI, Shen L, Paner GP, Amit AS, Kang C, Geddes JE, Allison JP, Socci ND, Savage PA. Re: Aire-dependent thymic development of tumor-associated regulatory T cells Journal of Urology. 190: 1954. PMID 24120816 DOI: 10.1016/J.Juro.2013.07.027 |
0.528 |
|
2013 |
Malchow S, Leventhal DS, Savage PA. Organ-specific regulatory T cells of thymic origin are expanded in murine prostate tumors. Oncoimmunology. 2: e24898. PMID 24073374 DOI: 10.4161/Onci.24898 |
0.473 |
|
2013 |
Malchow S, Leventhal DS, Nishi S, Fischer BI, Shen L, Paner GP, Amit AS, Kang C, Geddes JE, Allison JP, Socci ND, Savage PA. Aire-dependent thymic development of tumor-associated regulatory T cells. Science (New York, N.Y.). 339: 1219-24. PMID 23471412 DOI: 10.1126/Science.1233913 |
0.56 |
|
2013 |
Jain N, Liu H, Artz AS, Anastasi J, Odenike O, Godley LA, Joseph L, Marino S, Kline J, Nguyen V, Schouten V, Kunnavakkam R, Larson RA, Stock W, Ulaszek J, ... Savage PA, et al. Immune reconstitution after combined haploidentical and umbilical cord blood transplant. Leukemia & Lymphoma. 54: 1242-9. PMID 23088744 DOI: 10.3109/10428194.2012.739688 |
0.442 |
|
2013 |
Savage PA, Malchow S, Leventhal DS. Basic principles of tumor-associated regulatory T cell biology. Trends in Immunology. 34: 33-40. PMID 22999714 DOI: 10.1016/J.It.2012.08.005 |
0.506 |
|
2013 |
Leventhal D, Malchow S, Cai Y, Griend DV, Savage P. Abstract 452: Murine prostate tumors recruit endogenous, thymic-derived regulatory T cells which are redistributed following castration. Cancer Research. 73: 452-452. DOI: 10.1158/1538-7445.Am2013-452 |
0.493 |
|
2011 |
Donkor MK, Sarkar A, Savage PA, Franklin RA, Johnson LK, Jungbluth AA, Allison JP, Li MO. T cell surveillance of oncogene-induced prostate cancer is impeded by T cell-derived TGF-β1 cytokine. Immunity. 35: 123-34. PMID 21757379 DOI: 10.1016/J.Immuni.2011.04.019 |
0.522 |
|
2010 |
Nalle SC, Savage PA, Turner JR. Total Body Irradiation Creates a Proinflammatory Milieu That Is Required for Minor, but Not Major, Mismatch Graft-Versus-Host-Disease. Blood. 116: 3736-3736. DOI: 10.1182/Blood.V116.21.3736.3736 |
0.327 |
|
2008 |
Savage PA, Vosseller K, Kang C, Larimore K, Riedel E, Wojnoonski K, Jungbluth AA, Allison JP. Recognition of a ubiquitous self antigen by prostate cancer-infiltrating CD8+ T lymphocytes. Science (New York, N.Y.). 319: 215-20. PMID 18187659 DOI: 10.1126/Science.1148886 |
0.564 |
|
2001 |
Savage PA, Davis MM. A kinetic window constricts the T cell receptor repertoire in the thymus. Immunity. 14: 243-52. PMID 11290334 DOI: 10.1016/S1074-7613(01)00106-6 |
0.634 |
|
1999 |
Davis MM, Wülfing C, Krummel MF, Savage PA, Xu J, Sumen C, Dustin ML, Chien YH. Visualizing T-cell recognition. Cold Spring Harbor Symposia On Quantitative Biology. 64: 243-51. PMID 11232292 DOI: 10.1101/Sqb.1999.64.243 |
0.613 |
|
1999 |
Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD, Roederer M, Davis MM. Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nature Medicine. 5: 677-85. PMID 10371507 DOI: 10.1038/9525 |
0.655 |
|
1999 |
Savage PA, Boniface JJ, Davis MM. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity. 10: 485-92. PMID 10229191 DOI: 10.1016/S1074-7613(00)80048-5 |
0.587 |
|
1999 |
Yee C, Savage PA, Lee PP, Davis MM, Greenberg PD. Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers. Journal of Immunology (Baltimore, Md. : 1950). 162: 2227-34. PMID 9973498 |
0.499 |
|
1994 |
Rubnitz J, Morrissey J, Savage P, Cleary M. ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional activation potential in lymphoid and myeloid cells Blood. 84: 1747-1752. DOI: 10.1182/Blood.V84.6.1747.Bloodjournal8461747 |
0.359 |
|
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