W. V. Graham, Ph.D. - Related publications

2010 Pathology University of Chicago, Chicago, IL 
Molecular Biology, Cell Biology, General Biology
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Lin HH, Hsieh MC, Wang CP, Yu PR, Lee MS, Chen JH. Anti-Atherosclerotic Effect of Gossypetin on Abnormal Vascular Smooth Muscle Cell Proliferation and Migration. Antioxidants (Basel, Switzerland). 10. PMID 34572989 DOI: 10.3390/antiox10091357   
2021 Ali S, Khan MR, Iqbal J, Batool R, Naz I, Yaseen T, Abbasi BA, Nasir JA, El-Serehy HA. Chemical composition and pharmacological bio-efficacy of (Decne) Rehder for anticancer activity. Saudi Journal of Biological Sciences. 28: 4969-4986. PMID 34466072 DOI: 10.1016/j.sjbs.2021.07.072   
2021 Carrasco-Navarro U, Aguirre J. HO Induces Major Phosphorylation Changes in Critical Regulators of Signal Transduction, Gene Expression, Metabolism and Developmental Networks in . Journal of Fungi (Basel, Switzerland). 7. PMID 34436163 DOI: 10.3390/jof7080624   
2021 Chaisit S, Jianmongkol S. Apoptosis Inducing Activity of Rhinacanthin-C in Doxorubicin-Resistant Breast Cancer MCF-7 Cells. Biological & Pharmaceutical Bulletin. 44: 1239-1246. PMID 34471052 DOI: 10.1248/bpb.b21-00015   
2021 Drysch M, Schmidt SV, Becerikli M, Reinkemeier F, Dittfeld S, Wagner JM, Dadras M, Sogorski A, von Glinski M, Lehnhardt M, Behr B, Wallner C. Myostatin Deficiency Protects C2C12 Cells from Oxidative Stress by Inhibiting Intrinsic Activation of Apoptosis. Cells. 10. PMID 34359850 DOI: 10.3390/cells10071680   
2021 Qin L, Cao X, Kaneko T, Voss C, Liu X, Wang G, Li SS. Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors. The Journal of Biological Chemistry. 101161. PMID 34480897 DOI: 10.1016/j.jbc.2021.101161   
2021 Mysore VP, Zhou ZW, Ambrogio C, Li L, Kapp JN, Lu C, Wang Q, Tucker MR, Okoro JJ, Nagy-Davidescu G, Bai X, Plückthun A, Jänne PA, Westover KD, Shan Y, et al. A structural model of a Ras-Raf signalosome. Nature Structural & Molecular Biology. 28: 847-857. PMID 34625747 DOI: 10.1038/s41594-021-00667-6   
2021 Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, et al. TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth. Nature Communications. 12: 5337. PMID 34504101 DOI: 10.1038/s41467-021-25622-3   
2021 Kondo Y, Paul JW, Subramaniam S, Kuriyan J. New insights into Raf regulation from structural analyses. Current Opinion in Structural Biology. 71: 223-231. PMID 34454301 DOI: 10.1016/j.sbi.2021.07.005   
2021 Rho SB, Lee KW, Lee SH, Byun HJ, Kim BR, Lee CH. Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer. Biomolecules & Therapeutics. 29: 506-518. PMID 34462379 DOI: 10.4062/biomolther.2021.121   
2021 Lin ZY, Yun QZ, Wu L, Zhang TW, Yao TZ. Pharmacological basis and new insights of deguelin concerning its anticancer effects. Pharmacological Research. 105935. PMID 34644595 DOI: 10.1016/j.phrs.2021.105935   
2021 Lan CN, Cai WJ, Shi J, Yi ZJ. MAPK inhibitors protect against early‑stage osteoarthritis by activating autophagy. Molecular Medicine Reports. 24. PMID 34590154 DOI: 10.3892/mmr.2021.12469   
2021 Zheng Y, Ding W, Zhang T, Zhao Z, Wang R, Li Z, Yu S, Li J, Zhao X, Wu Q. Antimony-induced astrocyte activation via mitogen-activated protein kinase activation-dependent CREB phosphorylation. Toxicology Letters. PMID 34571074 DOI: 10.1016/j.toxlet.2021.09.006   
2021 Karia P, Yoshioka K, Moeder W. Multiple phosphorylation events of the mitochondrial membrane protein TTM1 regulate cell death during senescence. The Plant Journal : For Cell and Molecular Biology. PMID 34409658 DOI: 10.1111/tpj.15470   
2021 Minakhina S, De Oliveira V, Kim SY, Zheng H, Wondisford FE. Thyroid hormone receptor phosphorylation regulates acute fasting-induced suppression of the hypothalamic-pituitary-thyroid axis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34544870 DOI: 10.1073/pnas.2107943118   
2021 Zhang S, Chen H, Li C, Chen B, Gong H, Zhao Y, Qi R. Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets. Frontiers in Pharmacology. 12: 746107. PMID 34646142 DOI: 10.3389/fphar.2021.746107   
2021 Ramadan M, A M M Elshaier Y, Aly AA, Abdel-Aziz M, Fathy HM, Brown AB, Pridgen JR, Dalby KN, Kaoud TS. Development of 2'-aminospiro [pyrano[3,2-c]quinoline]-3'-carbonitrile derivatives as non-ATP competitive Src kinase inhibitors that suppress breast cancer cell migration and proliferation. Bioorganic Chemistry. 116: 105344. PMID 34598088 DOI: 10.1016/j.bioorg.2021.105344   
2021 Geng Q, Liu B, Zhao PC, Xiong YB, Li L, Yi JF, Lyu C. [Molecular mechanism of Fagopyri Dibotryis Rhizoma in treatment of acute lung injury based on network pharmacology and in vitro experiments]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 4816-4823. PMID 34581093 DOI: 10.19540/j.cnki.cjcmm.20210524.401   
2021 Liu J, Jiang R, Zhou J, Xu X, Sun Z, Li J, Chen X, Li Z, Yan X, Zhao D, Zheng Z, Sun L. Salicylic acid in ginseng root alleviates skin hyperpigmentation disorders by inhibiting melanogenesis and melanosome transport. European Journal of Pharmacology. 174458. PMID 34480884 DOI: 10.1016/j.ejphar.2021.174458   
2021 Ma J, Ren Y, Zhang JN, Lin L, Zhang YL. [Analysis on targets of regulating Qi and activating blood based on activity spectrum of targets]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 3970-3979. PMID 34472274 DOI: 10.19540/j.cnki.cjcmm.20210303.401   
2021 Bie N, Feng X, Li C, Meng M, Wang C. The Protective Effect of Docosahexaenoic Acid on PC12 Cells in Oxidative Stress Induced by HO through the TrkB-Erk1/2-CREB Pathway. Acs Chemical Neuroscience. PMID 34428890 DOI: 10.1021/acschemneuro.1c00421   
2021 Jia B, Yu S, Yu D, Liu N, Zhang S, Wu A. Mycotoxin deoxynivalenol affects myoblast differentiation via downregulating cytoskeleton and ECM-integrin-FAK-RAC-PAK signaling pathway. Ecotoxicology and Environmental Safety. 226: 112850. PMID 34607188 DOI: 10.1016/j.ecoenv.2021.112850   
2021 Thengchaisri N, Hein TW, Ren Y, Kuo L. Activation of Coronary Arteriolar PKCβ2 Impairs Endothelial NO-Mediated Vasodilation: Role of JNK/Rho Kinase Signaling and Xanthine Oxidase Activation. International Journal of Molecular Sciences. 22. PMID 34575925 DOI: 10.3390/ijms22189763   
2021 Dong Y, Han H, Li Y, Guo L. [Roles of Histidine Kinases and Histidine Phosphatases in Cancer]. Zhongguo Fei Ai Za Zhi = Chinese Journal of Lung Cancer. PMID 34455734 DOI: 10.3779/j.issn.1009-3419.2021.102.28   
2021 Nosratpour S, Ndiaye K. Ankyrin-repeat and SOCS box-containing protein 9 (ASB9) regulates ovarian granulosa cells function and MAPK signaling. Molecular Reproduction and Development. PMID 34476862 DOI: 10.1002/mrd.23532   
2021 Limaye AJ, Bendzunas GN, Kennedy EJ. Targeted disruption of PKC from AKAP signaling complexes. Rsc Chemical Biology. 2: 1227-1231. PMID 34458835 DOI: 10.1039/d1cb00106j   
2021 Kim JY, Park HH, Yong TS, Jeon SH. Lithium chloride inhibits the migration and invasion of osteosarcoma cells by blocking nuclear translocation of phospho-Erk. Biochemical and Biophysical Research Communications. 581: 74-80. PMID 34656851 DOI: 10.1016/j.bbrc.2021.10.025   
2021 Xu Y, Ji Y, Li X, Ding J, Chen L, Huang Y, Wei W. URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells. International Journal of Biological Sciences. 17: 3091-3103. PMID 34421352 DOI: 10.7150/ijbs.55689   
2021 Cabarca S, Frazão de Souza M, Albert de Oliveira A, Vignoli Muniz GS, Lamy MT, Vinicius Dos Reis C, Takarada J, Effer B, Souza LS, Iriarte de la Torre L, Couñago R, Pinto Oliveira CL, Balan A. Structure of the PknF and conformational changes induced in forkhead-associated regulatory domains. Current Research in Structural Biology. 3: 165-178. PMID 34382010 DOI: 10.1016/j.crstbi.2021.07.001   
2021 Ramesh ST, Navyasree KV, Sah S, Ashok AB, Qathoon N, Mohanty S, Swain RK, Umasankar PK. BMP2K phosphorylates AP-2 and regulates clathrin-mediated endocytosis. Traffic (Copenhagen, Denmark). PMID 34480404 DOI: 10.1111/tra.12814   
2021 Luci C, Vieira E, Bourinet M, Rousseau D, Bonnafous S, Patouraux S, Lefevre L, Larbret F, Prod'homme V, Iannelli A, Tran A, Anty R, Bailly-Maitre B, Deckert M, Gual P. SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis. Cellular and Molecular Gastroenterology and Hepatology. PMID 34411785 DOI: 10.1016/j.jcmgh.2021.08.004   
2021 Wang W, Dai Z, Li J, Ouyang J, Li T, Zeng B, Kang L, Jia K, Xi Z, Jia W. A Method for Assaying of Protein Kinase Activity In Vivo and Its Use in Studies of Signal Transduction in Strawberry Fruit Ripening. International Journal of Molecular Sciences. 22. PMID 34638834 DOI: 10.3390/ijms221910495   
2021 Preynat-Seauve O, Nguyen EB, Westermaier Y, Héritier M, Tardy S, Cambet Y, Feyeux M, Caillon A, Scapozza L, Krause KH. Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation. Frontiers in Pharmacology. 12: 664608. PMID 34421588 DOI: 10.3389/fphar.2021.664608   
2021 Zhu G, Herlyn M, Yang X. TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination. Nature Cell Biology. 23: 978-991. PMID 34497368 DOI: 10.1038/s41556-021-00732-8   
2021 Woodall NB, Weinberg Z, Park J, Busch F, Johnson RS, Feldbauer MJ, Murphy M, Ahlrichs M, Yousif I, MacCoss MJ, Wysocki VH, El-Samad H, Baker D. De novo design of tyrosine and serine kinase-driven protein switches. Nature Structural & Molecular Biology. 28: 762-770. PMID 34518698 DOI: 10.1038/s41594-021-00649-8   
2021 Pan S, Zhang L, Liu Z, Xing H. Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes. Journal of Animal Science. PMID 34634123 DOI: 10.1093/jas/skab287   
2021 Ballard DJ, Peng HY, Das JK, Kumar A, Wang L, Ren Y, Xiong X, Ren X, Yang JM, Song J. Insights Into the Pathologic Roles and Regulation of Eukaryotic Elongation Factor-2 Kinase. Frontiers in Molecular Biosciences. 8: 727863. PMID 34532346 DOI: 10.3389/fmolb.2021.727863   
2021 Karamafrooz A, Brennan J, Thomas DD, Parker LL. Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A () and Its Oncogenic Mutant 1. Journal of Proteome Research. PMID 34436901 DOI: 10.1021/acs.jproteome.1c00500   
2021 Zheng CR, Singh A, Libby A, Silver PA, Libby EA. Modular and Single-Cell Sensors of Bacterial Ser/Thr Kinase Activity. Acs Synthetic Biology. PMID 34463482 DOI: 10.1021/acssynbio.1c00250   
2021 Hassoun R, Budde H, Zhazykbayeva S, Herwig M, Sieme M, Delalat S, Mostafi N, Gömöri K, Tangos M, Jarkas M, Pabel S, Bruckmüller S, Skrygan M, Lódi M, Jaquet K, et al. Stress activated signalling impaired protein quality control pathways in human hypertrophic cardiomyopathy. International Journal of Cardiology. PMID 34517018 DOI: 10.1016/j.ijcard.2021.09.009   
2021 Jin YJ, Chennupati R, Li R, Liang G, Wang S, Iring A, Graumann J, Wettschureck N, Offermanns S. Protein kinase N2 mediates flow-induced eNOS activation and vascular tone regulation. The Journal of Clinical Investigation. PMID 34499618 DOI: 10.1172/JCI145734   
2021 Gong YT, Li YP, Cheng YR, Shi XJ, Yang L, Yang DP, Xu WJ, Dong L. [Molecular mechanism of Qishen Yiqi Dripping Pills in treating myocardial ischemia:a study based on HIF-1 signaling pathway]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 3949-3959. PMID 34472272 DOI: 10.19540/j.cnki.cjcmm.20210524.702   
2021 Balogun O, Kang HW. Garlic Scape ( L.) Extract Decreases Adipogenesis by Activating AMK-Activated Protein Kinase During the Differentiation in 3T3-L1 Adipocytes. Journal of Medicinal Food. PMID 34619042 DOI: 10.1089/jmf.2021.0014   
2021 Xu W, Kannan S, Verma CS, Nacro K. Update on the Development of MNK Inhibitors as Therapeutic Agents. Journal of Medicinal Chemistry. PMID 34533957 DOI: 10.1021/acs.jmedchem.1c00368   
2021 Blaustein M, Piegari E, Martínez Calejman C, Vila A, Amante A, Manese MV, Zeida A, Abrami L, Veggetti M, Guertin DA, van der Goot FG, Corvi MM, Colman-Lerner A. Akt Is S-Palmitoylated: A New Layer of Regulation for Akt. Frontiers in Cell and Developmental Biology. 9: 626404. PMID 33659252 DOI: 10.3389/fcell.2021.626404   
2021 Shaw LM. TBK1 has a new Akt. The Journal of Biological Chemistry. 297: 101244. PMID 34563542 DOI: 10.1016/j.jbc.2021.101244   
2021 Bi C, Zhang X, Chen Y, Dong Y, Shi Y, Lei Y, Lv D, Cao X, Li W, Shi H. MAGT1 is required for HeLa cell proliferation through regulating p21 expression, S-phase progress, and ERK/p38 MAPK MYC axis. Cell Cycle (Georgetown, Tex.). 1-15. PMID 34499581 DOI: 10.1080/15384101.2021.1974792   
2021 Asati V, Anant A, Patel P, Kaur K, Gupta GD. Pyrazolopyrimidines as anticancer agents: A review on structural and target-based approaches. European Journal of Medicinal Chemistry. 225: 113781. PMID 34438126 DOI: 10.1016/j.ejmech.2021.113781   
2021 Ramshekar A, Wang H, Hartnett ME. Regulation of Rac1 Activation in Choroidal Endothelial Cells: Insights into Mechanisms in Age-Related Macular Degeneration. Cells. 10. PMID 34572063 DOI: 10.3390/cells10092414   
2021 An C, Huang Y, Li M, Xue F, Nie D, Zhao H, Chen L, Yazdanbakhsh K, Sun L, Jiang Z, Mohandas N, An X. Vesicular formation regulated by ERK/MAPK pathway mediates human erythroblast enucleation. Blood Advances. PMID 34551066 DOI: 10.1182/bloodadvances.2021004859