Alexandra R. Grassian, Ph.D. - Publications

2011 Harvard University, Cambridge, MA, United States 
Cell Biology, Oncology

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Grassian AR, Scales TM, Knutson SK, Kuntz KW, McCarthy NJ, Lowe CE, Moore JD, Copeland RA, Keilhack H, Smith JJ, Wickenden JA, Ribich S. A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality. Biological Procedures Online. 17: 15. PMID 26578851 DOI: 10.1186/s12575-015-0028-4  0.56
2014 Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, et al. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism. Cancer Research. 74: 3317-31. PMID 24755473 DOI: 10.1158/0008-5472.CAN-14-0772-T  0.56
2014 Grassian AR, Pagliarini R, Chiang DY. Mutations of isocitrate dehydrogenase 1 and 2 in intrahepatic cholangiocarcinoma. Current Opinion in Gastroenterology. 30: 295-302. PMID 24569570 DOI: 10.1097/MOG.0000000000000050  0.56
2012 Grassian AR, Lin F, Barrett R, Liu Y, Jiang W, Korpal M, Astley H, Gitterman D, Henley T, Howes R, Levell J, Korn JM, Pagliarini R. Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT). The Journal of Biological Chemistry. 287: 42180-94. PMID 23038259 DOI: 10.1074/jbc.M112.417832  0.56
2011 Grassian AR, Coloff JL, Brugge JS. Extracellular matrix regulation of metabolism and implications for tumorigenesis. Cold Spring Harbor Symposia On Quantitative Biology. 76: 313-24. PMID 22105806 DOI: 10.1101/sqb.2011.76.010967  0.56
2011 Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G, Brugge JS. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes & Development. 25: 1716-33. PMID 21852536 DOI: 10.1101/gad.16771811  0.56
2011 Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics. 43: 869-74. PMID 21804546 DOI: 10.1038/ng.890  0.56
2011 Grassian AR, Schafer ZT, Brugge JS. ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells. The Journal of Biological Chemistry. 286: 79-90. PMID 20956544 DOI: 10.1074/jbc.M110.169821  0.56
2009 Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461: 109-13. PMID 19693011 DOI: 10.1038/nature08268  0.56
2008 Melet A, Song K, Bucur O, Jagani Z, Grassian AR, Khosravi-Far R. Apoptotic pathways in tumor progression and therapy. Advances in Experimental Medicine and Biology. 615: 47-79. PMID 18437891 DOI: 10.1007/978-1-4020-6554-5_4  0.56
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