Crystal M. Ripplinger, Ph.D. - Publications

Affiliations: 
2008 Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical Engineering

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Christoph J, Ripplinger CM. Paralysis by analysis: Overcoming cardiac contraction with computer vision. Proceedings of the National Academy of Sciences of the United States of America. 120: e2314448120. PMID 37792520 DOI: 10.1073/pnas.2314448120  0.303
2023 Yang PC, Rose A, DeMarco KR, Dawson JRD, Han Y, Jeng MT, Harvey RD, Santana LF, Ripplinger CM, Vorobyov I, Lewis TJ, Clancy CE. A multiscale predictive digital twin for neurocardiac modulation. The Journal of Physiology. PMID 37528537 DOI: 10.1113/JP284391  0.303
2023 van Weperen VYH, Ripplinger CM, Vaseghi M. Autonomic control of ventricular function in health and disease: current state of the art. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 1-27. PMID 37166736 DOI: 10.1007/s10286-023-00948-8  0.306
2021 Swift LM, Kay MW, Ripplinger CM, Posnack NG. Stop the beat to see the rhythm: excitation-contraction uncoupling in cardiac research. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34623183 DOI: 10.1152/ajpheart.00477.2021  0.339
2020 Tapa S, Wang L, Francis Stuart SD, Wang Z, Jiang Y, Habecker BA, Ripplinger CM. Adrenergic supersensitivity and impaired neural control of cardiac electrophysiology following regional cardiac sympathetic nerve loss. Scientific Reports. 10: 18801. PMID 33139790 DOI: 10.1038/s41598-020-75903-y  0.325
2020 Wang Z, Tapa S, Francis Stuart SD, Wang L, Bossuyt J, Delisle BP, Ripplinger CM. Aging Disrupts Normal Time-of-day Variation in Cardiac Electrophysiology. Circulation. Arrhythmia and Electrophysiology. PMID 32706628 DOI: 10.1161/Circep.119.008093  0.36
2020 Wang L, Olivas A, Francis Stuart SD, Tapa S, Blake M, Woodward WR, Habecker BA, Ripplinger CM. Cardiac sympathetic nerve transdifferentiation reduces action potential heterogeneity after myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31975627 DOI: 10.1152/Ajpheart.00412.2019  0.407
2020 Grandi E, Ni H, Iseppe AF, Ghayoumi B, Wang L, Jiang Y, Chen Y, Bers DM, Sato D, Edwards AG, Ripplinger CM, Morotti S. SPARC: Found in translation: quantitative predictors of cardiac myocyte responses to β‐adrenergic stimulation across species The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06511  0.362
2020 Hegyi B, Fasoli A, Ko CY, Ciccozzi MM, Tapa S, Van BW, Shen EY, Baidar S, Bossuyt J, Ripplinger CM, Bers DM. O-Glycosylation of Camkii at Serine 280 Promotes Cardiac Arrhythmias in Diabetic Hyperglycemia Biophysical Journal. 118: 103a. DOI: 10.1016/J.Bpj.2019.11.720  0.311
2019 Wang L, Morotti S, Tapa S, Francis Stuart SD, Jiang Y, Wang Z, Myles RC, Brack KE, Ng GA, Bers DM, Grandi E, Ripplinger CM. Different paths, same destination: divergent action potential responses produce conserved cardiac fight-or-flight response in mouse and rabbit hearts. The Journal of Physiology. PMID 31215643 DOI: 10.1113/Jp278016  0.435
2019 Grandi E, Ripplinger CM. Antiarrhythmic mechanisms of beta blocker therapy. Pharmacological Research. 104274. PMID 31100336 DOI: 10.1016/J.Phrs.2019.104274  0.39
2018 Wang Z, Wang L, Tapa S, Pinkerton KE, Chen CY, Ripplinger CM. Exposure to Secondhand Smoke and Arrhythmogenic Cardiac Alternans in a Mouse Model. Environmental Health Perspectives. 126: 127001. PMID 30675795 DOI: 10.1289/Ehp3664  0.305
2018 Lindsey ML, Jung M, Yabluchanskiy A, Cannon PL, Padmanabhan Iyer R, Flynn ER, DeLeon-Pennell KY, Valerio FM, Harrison CL, Ripplinger CM, Hall ME, Ma Y. Exogenous CXCL4 Infusion Inhibits Macrophage Phagocytosis by Limiting CD36 Signaling to Enhance Post-myocardial Infarction Cardiac Dilation and Mortality. Cardiovascular Research. PMID 30169632 DOI: 10.1093/Cvr/Cvy211  0.35
2018 Ripplinger CM. The best thing since sliced bread? Optical mapping of transverse cardiac slices in the mouse heart. The Journal of Physiology. PMID 29974471 DOI: 10.1113/Jp276669  0.389
2018 Francis Stuart SD, Wang L, Woodard WR, Ng GA, Habecker BA, Ripplinger CM. Age-related changes in cardiac electrophysiology and calcium handling in response to sympathetic nerve stimulation. The Journal of Physiology. PMID 29938794 DOI: 10.1113/Jp276396  0.351
2018 Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, ... ... Ripplinger CM, et al. Guidelines for experimental models of myocardial ischemia and infarction. American Journal of Physiology. Heart and Circulatory Physiology. 314: H812-H838. PMID 29351451 DOI: 10.1152/Ajpheart.00335.2017  0.33
2018 Stuart SF, Wang L, Woodard W, Habecker B, Ripplinger C. Age-related changes in sympathetic responsiveness and cardiac electrophysiology Journal of Molecular and Cellular Cardiology. 124: 89. DOI: 10.1016/J.Yjmcc.2018.07.025  0.339
2018 Tapa S, Wang L, Stuart SF, Ripplinger C. Regional cardiac sympathetic denervation produces supersensitivity of action potential and Ca2+ handling properties to β–adrenergic stimulation Journal of Molecular and Cellular Cardiology. 124: 88-89. DOI: 10.1016/J.Yjmcc.2018.07.024  0.368
2018 Wang L, Morotti S, Tapa S, Francis Stuart SD, Jiang Y, Bers DM, Grandi E, Ripplinger CM. Dual optical mapping of the innervated mouse heart reveals unique electrophysiological responses during fight-or-flight Journal of Molecular and Cellular Cardiology. 124: 88. DOI: 10.1016/J.Yjmcc.2018.07.023  0.373
2017 Parrish DC, Francis Stuart SD, Olivas A, Wang L, Nykjaer A, Ripplinger CM, Habecker BA. Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00300.2017. PMID 29101167 DOI: 10.1152/Ajpheart.00300.2017  0.422
2017 Lang D, Sato D, Jiang Y, Ginsburg KS, Ripplinger CM, Bers DM. Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart. Circulation Research. PMID 28970285 DOI: 10.1161/Circresaha.117.312050  0.389
2017 Murphy SR, Wang L, Wang Z, Domondon P, Lang D, Habecker BA, Myles RC, Ripplinger CM. β-Adrenergic Inhibition Prevents Action Potential and Calcium Handling Changes during Regional Myocardial Ischemia. Frontiers in Physiology. 8: 630. PMID 28894423 DOI: 10.3389/Fphys.2017.00630  0.397
2017 Ripplinger CM. From drugs to devices and back again: chemical vagal nerve stimulation for the treatment of heart failure. Cardiovascular Research. 113: 1270-1272. PMID 28859301 DOI: 10.1093/Cvr/Cvx142  0.308
2017 Zucker IH, Lindsey ML, Delmar M, De Windt LJ, Des Rosiers C, Diz DI, Hester RL, Jones SP, Kanagy NL, Kitakaze M, Liao R, Lopaschuk GD, Patel KP, Recchia FA, Sadoshima J, ... ... Ripplinger CM, et al. Why Publish in the American Journal of Physiology-Heart and Circulatory Physiology? American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00329.2017. PMID 28626081 DOI: 10.1152/Ajpheart.00329.2017  0.525
2017 Tapa S, Wang L, Stuart SF, Ripplinger C. Regional cardiac denervation produces supersensitivity of myocardial Ca 2+ handling to β-adrenergic stimulation Journal of Molecular and Cellular Cardiology. 112: 152. DOI: 10.1016/J.Yjmcc.2017.07.066  0.372
2017 Wang L, Tapa S, Stuart S, Myles R, Brack K, Ng A, Bers D, Ripplinger C. Dual optical mapping of the innervated Langendorff-perfused heart reveals novel insights into acute electrophysiological responses to sympathetic stimulation Journal of Molecular and Cellular Cardiology. 112: 151-152. DOI: 10.1016/J.Yjmcc.2017.07.064  0.384
2016 Chiamvimonvat N, Chen-Izu Y, Clancy CE, Deschenes I, Dobrev D, Heijman J, Izu L, Qu Z, Ripplinger CM, Vandenberg JI, Weiss JN, Koren G, Banyasz T, Grandi E, Sanguinetti MC, et al. Potassium currents in the heart: Functional roles in repolarization, arrhythmia and therapeutics. The Journal of Physiology. PMID 27808412 DOI: 10.1113/Jp272883  0.389
2016 Sirish P, Li N, Timofeyev V, Zhang XD, Wang L, Yang J, Lee KS, Bettaieb A, Ma SM, Lee JH, Su D, Lau VC, Myers RE, Lieu DK, López JE, ... ... Ripplinger CM, et al. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circulation. Arrhythmia and Electrophysiology. 9. PMID 27162031 DOI: 10.1161/Circep.115.003721  0.313
2016 Habecker BA, Anderson ME, Birren SJ, Fukuda K, Herring N, Hoover DB, Kanazawa H, Paterson DJ, Ripplinger CM. Molecular and cellular neurocardiology: Development, cellular and molecular adaptations to heart disease. The Journal of Physiology. PMID 27060296 DOI: 10.1113/Jp271840  0.328
2016 Gardner RT, Ripplinger CM, Myles RC, Habecker BA. Molecular Mechanisms of Sympathetic Remodeling and Arrhythmias. Circulation. Arrhythmia and Electrophysiology. 9: e001359. PMID 26810594 DOI: 10.1161/Circep.115.001359  0.451
2016 Ripplinger CM, Noujaim SF, Linz D. The Nervous Heart. Progress in Biophysics and Molecular Biology. PMID 26780507 DOI: 10.1016/J.Pbiomolbio.2015.12.015  0.437
2016 Quinn TA, Ripplinger CM. Recent developments in biophysics & molecular biology of heart rhythm. Progress in Biophysics and Molecular Biology. PMID 26777585 DOI: 10.1016/J.Pbiomolbio.2016.01.006  0.359
2016 Olivas A, Gardner RT, Wang L, Ripplinger CM, Woodward WR, Habecker BA. Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 479-88. PMID 26758839 DOI: 10.1523/Jneurosci.3556-15.2016  0.416
2015 Francis Stuart SD, De Jesus NM, Lindsey ML, Ripplinger CM. The crossroads of inflammation, fibrosis, and arrhythmia following myocardial infarction. Journal of Molecular and Cellular Cardiology. 91: 114-122. PMID 26739214 DOI: 10.1016/J.Yjmcc.2015.12.024  0.318
2015 Wang L, De Jesus NM, Ripplinger CM. Optical Mapping of Intra-Sarcoplasmic Reticulum Ca2+ and Transmembrane Potential in the Langendorff-perfused Rabbit Heart. Journal of Visualized Experiments : Jove. PMID 26382577 DOI: 10.3791/53166  0.319
2015 Bartos DC, Grandi E, Ripplinger CM. Ion Channels in the Heart. Comprehensive Physiology. 5: 1423-64. PMID 26140724 DOI: 10.1002/Cphy.C140069  0.424
2015 Ripplinger CM, Efimov IR. Dual Vm/Ca imaging of premature ventricular contractions: bridging the gap of anatomical scales. Circulation. Arrhythmia and Electrophysiology. 8: 529-30. PMID 26082526 DOI: 10.1161/Circep.115.002916  0.522
2015 Hammer KP, Ljubojevic S, Ripplinger CM, Pieske BM, Bers DM. Cardiac myocyte alternans in intact heart: Influence of cell-cell coupling and β-adrenergic stimulation. Journal of Molecular and Cellular Cardiology. 84: 1-9. PMID 25828762 DOI: 10.1016/J.Yjmcc.2015.03.012  0.443
2015 Myles RC, Wang L, Bers DM, Ripplinger CM. Decreased inward rectifying K+ current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart. The Journal of Physiology. 593: 1479-93. PMID 25772297 DOI: 10.1113/Jphysiol.2014.279638  0.435
2015 Ripplinger CM. A leap(frog) forward in understanding focal arrhythmia. The Journal of Physiology. 593: 1383-4. PMID 25772292 DOI: 10.1113/Jphysiol.2014.287128  0.349
2015 Gardner RT, Wang L, Lang BT, Cregg JM, Dunbar CL, Woodward WR, Silver J, Ripplinger CM, Habecker BA. Targeting protein tyrosine phosphatase σ after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias. Nature Communications. 6: 6235. PMID 25639594 DOI: 10.1038/Ncomms7235  0.444
2015 Ripplinger CM. Mouse models of cardiac conduction system markers: revealing the past, present, and future of pacemaking and conduction. Trends in Cardiovascular Medicine. 25: 10-1. PMID 25446050 DOI: 10.1016/J.Tcm.2014.09.007  0.401
2015 De Jesus NM, Wang L, Herren AW, Wang J, Shenasa F, Bers DM, Lindsey ML, Ripplinger CM. Atherosclerosis exacerbates arrhythmia following myocardial infarction: Role of myocardial inflammation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 12: 169-78. PMID 25304682 DOI: 10.1016/J.Hrthm.2014.10.007  0.38
2014 Wang L, Myles RC, De Jesus NM, Ohlendorf AK, Bers DM, Ripplinger CM. Optical mapping of sarcoplasmic reticulum Ca2+ in the intact heart: ryanodine receptor refractoriness during alternans and fibrillation. Circulation Research. 114: 1410-21. PMID 24568740 DOI: 10.1161/Circresaha.114.302505  0.323
2013 Feinberg AW, Ripplinger CM, van der Meer P, Sheehy SP, Domian I, Chien KR, Parker KK. Functional differences in engineered myocardium from embryonic stem cell-derived versus neonatal cardiomyocytes. Stem Cell Reports. 1: 387-96. PMID 24286027 DOI: 10.1016/J.Stemcr.2013.10.004  0.338
2013 Erickson JR, Pereira L, Wang L, Han G, Ferguson A, Dao K, Copeland RJ, Despa F, Hart GW, Ripplinger CM, Bers DM. Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation. Nature. 502: 372-6. PMID 24077098 DOI: 10.1038/Nature12537  0.337
2013 Gardner R, Wang L, Ripplinger C, Habecker B. Sympathetic reinnervation and arrhythmia prevention following cardiac ischemia-reperfusion injury Autonomic Neuroscience: Basic and Clinical. 177: 47. DOI: 10.1016/J.Autneu.2013.05.095  0.365
2012 Sondergaard CS, Mathews G, Wang L, Jeffreys A, Sahota A, Wood M, Ripplinger CM, Si MS. Contractile and electrophysiologic characterization of optimized self-organizing engineered heart tissue. The Annals of Thoracic Surgery. 94: 1241-8; discussion 1. PMID 22795054 DOI: 10.1016/J.Athoracsur.2012.04.098  0.367
2012 Feinberg AW, Alford PW, Jin H, Ripplinger CM, Werdich AA, Sheehy SP, Grosberg A, Parker KK. Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture. Biomaterials. 33: 5732-41. PMID 22594976 DOI: 10.1016/J.Biomaterials.2012.04.043  0.389
2012 Myles RC, Wang L, Kang C, Bers DM, Ripplinger CM. Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia. Circulation Research. 110: 1454-64. PMID 22539768 DOI: 10.1161/Circresaha.111.262345  0.384
2011 Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger CM, Kass RS, Clancy CE. A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Science Translational Medicine. 3: 98ra83. PMID 21885405 DOI: 10.1126/Scitranslmed.3002588  0.385
2011 Ambrosi CM, Ripplinger CM, Efimov IR, Fedorov VV. Termination of sustained atrial flutter and fibrillation using low-voltage multiple-shock therapy. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 101-8. PMID 20969974 DOI: 10.1016/J.Hrthm.2010.10.018  0.731
2009 Li W, Ripplinger CM, Lou Q, Efimov IR. Multiple monophasic shocks improve electrotherapy of ventricular tachycardia in a rabbit model of chronic infarction. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1020-7. PMID 19560090 DOI: 10.1016/J.Hrthm.2009.03.015  0.658
2009 Lombardi R, Rodriguez G, Chen SN, Ripplinger CM, Li W, Chen J, Willerson JT, Betocchi S, Wickline SA, Efimov IR, Marian AJ. Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation. 119: 1398-407. PMID 19255346 DOI: 10.1161/Circulationaha.108.790501  0.586
2009 Ripplinger CM, Lou Q, Li W, Hadley J, Efimov IR. Panoramic imaging reveals basic mechanisms of induction and termination of ventricular tachycardia in rabbit heart with chronic infarction: implications for low-voltage cardioversion. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 87-97. PMID 18996057 DOI: 10.1016/J.Hrthm.2008.09.019  0.707
2009 Ambrosi CM, Ripplinger CM, Efimov IR, Fedorov VV. Multiple Low-Energy Shock Therapy Terminates Atrial Flutter and Fibrillation More Effectively than ATP Heart Rhythm. 6: 1686-1687. DOI: 10.1016/J.Hrthm.2009.09.034  0.704
2009 Feinberg AW, Alford PW, Ripplinger CM, Adams WJ, Sheehy SP, Parker KK. Engineering Cardiac Contractility from the Sarcomere to Tissue-Scale Biophysical Journal. 96: 372a. DOI: 10.1016/J.Bpj.2008.12.2005  0.373
2009 Ripplinger CM, Efimov IR. The virtual electrode hypothesis of defibrillation Cardiac Bioelectric Therapy: Mechanisms and Practical Implications. 331-356. DOI: 10.1007/978-0-387-79403-7_13  0.529
2008 Hucker WJ, Ripplinger CM, Fleming CP, Fedorov VV, Rollins AM, Efimov IR. Bimodal biophotonic imaging of the structure-function relationship in cardiac tissue. Journal of Biomedical Optics. 13: 054012. PMID 19021392 DOI: 10.1117/1.2975826  0.704
2008 Lou Q, Ripplinger CM, Bayly PV, Efimov IR. Quantitative panoramic imaging of epicardial electrical activity. Annals of Biomedical Engineering. 36: 1649-58. PMID 18654852 DOI: 10.1007/S10439-008-9539-3  0.665
2008 Fleming CP, Ripplinger CM, Webb B, Efimov IR, Rollins AM. Quantification of cardiac fiber orientation using optical coherence tomography. Journal of Biomedical Optics. 13: 030505. PMID 18601522 DOI: 10.1117/1.2937470  0.536
2007 Ripplinger CM, Li W, Hadley J, Chen J, Rothenberg F, Lombardi R, Wickline SA, Marian AJ, Efimov IR. Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circulation Research. 101: 1049-57. PMID 17885214 DOI: 10.1161/Circresaha.107.161240  0.593
2007 Qu F, Ripplinger CM, Nikolski VP, Grimm C, Efimov IR. Three-dimensional panoramic imaging of cardiac arrhythmias in rabbit heart. Journal of Biomedical Optics. 12: 044019. PMID 17867823 DOI: 10.1117/1.2753748  0.609
2006 Efimov I, Ripplinger CM. Virtual electrode hypothesis of defibrillation. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 3: 1100-2. PMID 16945810 DOI: 10.1016/J.Hrthm.2006.03.005  0.577
2006 Ripplinger CM, Krinsky VI, Nikolski VP, Efimov IR. Mechanisms of unpinning and termination of ventricular tachycardia. American Journal of Physiology. Heart and Circulatory Physiology. 291: H184-92. PMID 16501014 DOI: 10.1152/Ajpheart.01300.2005  0.578
2006 Efimov IR, Ripplinger CM. Tornado in a dish: revealing the mechanisms of ventricular arrhythmias in engineered cardiac tissues. Cardiovascular Research. 69: 307-8. PMID 16325163 DOI: 10.1016/J.Cardiores.2005.10.012  0.54
2006 Ripplinger CM, Krinski VI, Nikolski VP, Efimov IR. AB9-6: Mechanisms of unpinning and termination of ventricular tachycardia Heart Rhythm. 3. DOI: 10.1016/J.Hrthm.2006.02.075  0.545
2005 Byrd GD, Prasad SM, Ripplinger CM, Cassilly TR, Schuessler RB, Boineau JP, Damiano RJ. Importance of geometry and refractory period in sustaining atrial fibrillation: testing the critical mass hypothesis. Circulation. 112: I7-13. PMID 16159868 DOI: 10.1161/Circulationaha.104.526210  0.347
2005 Ripplinger CM, Krinski VI, Nikolski VP, Efimov IR. Novel approach for low-voltage termination of anatomically defined reentry Heart Rhythm. 2: S142. DOI: 10.1016/J.Hrthm.2005.02.442  0.571
Show low-probability matches.