Nicholas R.J. Gascoigne - Publications

Affiliations: 
Scripps Research Institute 

102 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wojciech L, Png CW, Koh EY, Kioh DYQ, Deng L, Wang Z, Wu LZ, Hamidinia M, Tung DW, Zhang W, Pettersson S, Chan ECY, Zhang Y, Tan KS, Gascoigne NR. A tryptophan metabolite made by a gut microbiome eukaryote induces pro-inflammatory T cells. The Embo Journal. e112963. PMID 37743772 DOI: 10.15252/embj.2022112963  0.358
2023 Gautam N, Wojciech L, Yap J, Chua YL, Ding EM, Sim DC, Tan AS, Ahl PJ, Prasad M, Tung DW, Connolly JE, Adriani G, Brzostek J, Gascoigne NR. Themis controls T cell activation, effector functions, and metabolism of peripheral CD8 T cells. Life Science Alliance. 6. PMID 37739454 DOI: 10.26508/lsa.202302156  0.395
2019 Wu L, Brzostek J, Sankaran S, Tan T, Chan C, Yap J, Lai J, MacAry P, Gascoigne N. Abstract 1425: Chimeric antigen receptors based on T cell receptor-like antibodies Cancer Research. 79: 1425-1425. DOI: 10.1158/1538-7445.Am2019-1425  0.533
2018 Brameshuber M, Kellner F, Rossboth BK, Ta H, Alge K, Sevcsik E, Axmann M, Gascoigne NR, Davis SJ, Stockinger H, Schuetz GJ, Huppa JB. Monomeric TCR-CD3 Complexes Drive T-Cell Antigen Recognition Biophysical Journal. 114: 108a. DOI: 10.1016/J.Bpj.2017.11.626  0.509
2017 Brzostek J, Gascoigne NR. Thymic origins of T cell receptor alloreactivity. Transplantation. PMID 28114168 DOI: 10.1097/Tp.0000000000001654  0.558
2016 Chan JH, Chua YL, Peh HY, Jovanovic V, Gascoigne NR, Wong WS, Chew FT, Hanson BJ, Kemeny DM, MacAry PA. Molecular engineering of a therapeutic antibody for Blo t 5-induced allergic asthma. The Journal of Allergy and Clinical Immunology. PMID 27923562 DOI: 10.1016/J.Jaci.2016.10.028  0.308
2016 Gascoigne NR, Rybakin V, Acuto O, Brzostek J. TCR Signal Strength and T Cell Development. Annual Review of Cell and Developmental Biology. 32: 327-348. PMID 27712102 DOI: 10.1146/Annurev-Cellbio-111315-125324  0.454
2016 Gascoigne NR, Brzostek J, Mehta M, Acuto O. SHP1-ing thymic selection. European Journal of Immunology. 46: 2091-4. PMID 27600672 DOI: 10.1002/Eji.201646582  0.473
2016 Brzostek J, Gascoigne NR. Vive la peptide différence! Nature Immunology. 17: 896-8. PMID 27434001 DOI: 10.1038/Ni.3507  0.461
2016 Lai J, Tan WJ, Too CT, Choo JA, Wong LH, Bte Mustafa F, Srinivasan N, Lim AP, Zhong Y, Gascoigne NR, Hanson BJ, Chan SH, Chen J, MacAry PA. Targeting Epstein-Barr virus transformed B lymphoblastoid cells using antibodies with T cell receptor-like specificities. Blood. PMID 27338099 DOI: 10.1182/Blood-2016-03-707836  0.416
2016 Brzostek J, Gascoigne NR, Rybakin V. Cell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand Recognition. Frontiers in Immunology. 7: 24. PMID 26870040 DOI: 10.3389/Fimmu.2016.00024  0.534
2015 Almeida FF, Tenno M, Brzostek J, Li JL, Allies G, Hoeffel G, See P, Ng LG, Fehling HJ, Gascoigne NR, Taniuchi I, Ginhoux F. Identification of a novel lymphoid population in the murine epidermis. Scientific Reports. 5: 12554. PMID 26223192 DOI: 10.1038/Srep12554  0.507
2015 Rivino L, Kumaran EA, Thein TL, Too CT, Gan VC, Hanson BJ, Wilder-Smith A, Bertoletti A, Gascoigne NR, Lye DC, Leo YS, Akbar AN, Kemeny DM, MacAry PA. Virus-specific T lymphocytes home to the skin during natural dengue infection. Science Translational Medicine. 7: 278ra35. PMID 25761891 DOI: 10.1126/Scitranslmed.Aaa0526  0.459
2015 Gascoigne NR, Acuto O. THEMIS: a critical TCR signal regulator for ligand discrimination. Current Opinion in Immunology. 33: 86-92. PMID 25700024 DOI: 10.1016/J.Coi.2015.01.020  0.52
2015 Paster W, Bruger AM, Katsch K, Grégoire C, Roncagalli R, Fu G, Gascoigne NR, Nika K, Cohnen A, Feller SM, Simister PC, Molder KC, Cordoba SP, Dushek O, Malissen B, et al. A THEMIS:SHP1 complex promotes T-cell survival. The Embo Journal. 34: 393-409. PMID 25535246 DOI: 10.15252/Embj.201387725  0.5
2014 Rybakin V, Westernberg L, Fu G, Kim HO, Ampudia J, Sauer K, Gascoigne NR. Allelic exclusion of TCR α-chains upon severe restriction of Vα repertoire. Plos One. 9: e114320. PMID 25500569 DOI: 10.1371/Journal.Pone.0114320  0.503
2014 Gascoigne NR. Immunology: Tolerance lies in the timing. Nature. 515: 502-3. PMID 25428497 DOI: 10.1038/515502A  0.485
2014 Casas J, Brzostek J, Zarnitsyna VI, Hong JS, Wei Q, Hoerter JA, Fu G, Ampudia J, Zamoyska R, Zhu C, Gascoigne NR. Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor. Nature Communications. 5: 5624. PMID 25427562 DOI: 10.1038/Ncomms6624  0.44
2014 Fu G, Rybakin V, Brzostek J, Paster W, Acuto O, Gascoigne NR. Fine-tuning T cell receptor signaling to control T cell development. Trends in Immunology. 35: 311-8. PMID 24951034 DOI: 10.1016/J.It.2014.05.003  0.519
2014 Kong KF, Fu G, Zhang Y, Yokosuka T, Casas J, Canonigo-Balancio AJ, Becart S, Kim G, Yates JR, Kronenberg M, Saito T, Gascoigne NR, Altman A. Protein kinase C-η controls CTLA-4-mediated regulatory T cell function. Nature Immunology. 15: 465-72. PMID 24705298 DOI: 10.1038/Ni.2866  0.432
2014 Nabekura T, Kanaya M, Shibuya A, Fu G, Gascoigne NR, Lanier LL. Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection. Immunity. 40: 225-34. PMID 24440149 DOI: 10.1016/J.Immuni.2013.12.011  0.368
2013 Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JA, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR. Themis sets the signal threshold for positive and negative selection in T-cell development. Nature. 504: 441-5. PMID 24226767 DOI: 10.1038/Nature12718  0.563
2013 Brzostek J, Gascoigne NR. Too fast to die. Science Signaling. 6: pe33. PMID 24129699 DOI: 10.1126/Scisignal.2004753  0.422
2013 Mukherjee S, Rigaud S, Seok SC, Fu G, Prochenka A, Dworkin M, Gascoigne NR, Vieland VJ, Sauer K, Das J. In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness. Plos One. 8: e73937. PMID 24066087 DOI: 10.1371/Journal.Pone.0073937  0.315
2013 Hoerter JA, Brzostek J, Artyomov MN, Abel SM, Casas J, Rybakin V, Ampudia J, Lotz C, Connolly JM, Chakraborty AK, Gould KG, Gascoigne NR. Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC. The Journal of Experimental Medicine. 210: 1807-21. PMID 23940257 DOI: 10.1084/Jem.20122528  0.423
2013 Paster W, Brockmeyer C, Fu G, Simister PC, de Wet B, Martinez-Riaño A, Hoerter JA, Feller SM, Wülfing C, Gascoigne NR, Acuto O. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development. Journal of Immunology (Baltimore, Md. : 1950). 190: 3749-56. PMID 23460737 DOI: 10.4049/Jimmunol.1203389  0.412
2012 Rybakin V, Gascoigne NR. Negative selection assay based on stimulation of T cell receptor transgenic thymocytes with peptide-MHC tetramers. Plos One. 7: e43191. PMID 22900100 DOI: 10.1371/Journal.Pone.0043191  0.514
2012 Fu G, Gascoigne NR. The role of protein kinase cη in T cell biology. Frontiers in Immunology. 3: 177. PMID 22754555 DOI: 10.3389/Fimmu.2012.00177  0.538
2012 Fu G, Gascoigne NR. Protein kinase Cη, an emerging player in T-cell biology. Cell Cycle (Georgetown, Tex.). 11: 837-8. PMID 22356750 DOI: 10.4161/cc.11.5.19677  0.301
2011 Gascoigne NR, Casas J, Brzostek J, Rybakin V. Initiation of TCR phosphorylation and signal transduction. Frontiers in Immunology. 2: 72. PMID 22566861 DOI: 10.3389/Fimmu.2011.00072  0.414
2011 Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JA, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, ... Gascoigne NR, et al. Protein kinase C η is required for T cell activation and homeostatic proliferation. Science Signaling. 4: ra84. PMID 22155788 DOI: 10.1126/Scisignal.2002058  0.538
2011 Rybakin V, Clamme JP, Ampudia J, Yachi PP, Gascoigne NR. CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I. Embo Reports. 12: 1251-6. PMID 22081144 DOI: 10.1038/Embor.2011.209  0.454
2011 Gascoigne NR. T cell receptor structures: three for the price of one. Immunity. 35: 1-3. PMID 21777791 DOI: 10.1016/J.Immuni.2011.07.001  0.471
2011 Gascoigne NR, Palmer E. Signaling in thymic selection. Current Opinion in Immunology. 23: 207-12. PMID 21242076 DOI: 10.1016/J.Coi.2010.12.017  0.5
2011 Brockmeyer C, Paster W, Pepper D, Tan CP, Trudgian DC, McGowan S, Fu G, Gascoigne NR, Acuto O, Salek M. T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component. The Journal of Biological Chemistry. 286: 7535-47. PMID 21189249 DOI: 10.1074/Jbc.M110.201236  0.435
2010 Gascoigne NR. CD8+ thymocyte differentiation: T cell two-step. Nature Immunology. 11: 189-90. PMID 20157298 DOI: 10.1038/Ni0310-189  0.432
2010 Gascoigne NR, Zal T, Yachi PP, Hoerter JA. Co-receptors and recognition of self at the immunological synapse. Current Topics in Microbiology and Immunology. 340: 171-89. PMID 19960314 DOI: 10.1007/978-3-642-03858-7_9  0.549
2009 Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, ... Gascoigne NR, et al. Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nature Immunology. 10: 848-56. PMID 19597499 DOI: 10.1038/Ni.1766  0.557
2009 Gascoigne NR, Ampudia J, Clamme JP, Fu G, Lotz C, Mallaun M, Niederberger N, Palmer E, Rybakin V, Yachi PP, Zal T. Visualizing intermolecular interactions in T cells. Current Topics in Microbiology and Immunology. 334: 31-46. PMID 19521680 DOI: 10.1007/978-3-540-93864-4_2  0.476
2009 Singleton KL, Roybal KT, Sun Y, Fu G, Gascoigne NR, van Oers NS, Wülfing C. Spatiotemporal patterning during T cell activation is highly diverse. Science Signaling. 2: ra15. PMID 19351954 DOI: 10.1126/Scisignal.2000199  0.503
2008 Gascoigne NR. Do T cells need endogenous peptides for activation? Nature Reviews. Immunology. 8: 895-900. PMID 18846098 DOI: 10.1038/Nri2431  0.514
2008 Mallaun M, Naeher D, Daniels MA, Yachi PP, Hausmann B, Luescher IF, Gascoigne NR, Palmer E. The T cell receptor's alpha-chain connecting peptide motif promotes close approximation of the CD8 coreceptor allowing efficient signal initiation. Journal of Immunology (Baltimore, Md. : 1950). 180: 8211-21. PMID 18523287 DOI: 10.4049/Jimmunol.180.12.8211  0.674
2008 Haraldsson MK, Louis-Dit-Sully CA, Lawson BR, Sternik G, Santiago-Raber ML, Gascoigne NR, Theofilopoulos AN, Kono DH. The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation. Immunity. 28: 40-51. PMID 18199416 DOI: 10.1016/J.Immuni.2007.11.023  0.389
2007 Yachi PP, Lotz C, Ampudia J, Gascoigne NR. T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state. The Journal of Experimental Medicine. 204: 2747-57. PMID 17954567 DOI: 10.1084/Jem.20062610  0.545
2006 Daniels MA, Teixeiro E, Gill J, Hausmann B, Roubaty D, Holmberg K, Werlen G, Holländer GA, Gascoigne NR, Palmer E. Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling. Nature. 444: 724-9. PMID 17086201 DOI: 10.1038/Nature05269  0.675
2006 Zambricki E, Zal T, Yachi P, Shigeoka A, Sprent J, Gascoigne N, McKay D. In vivo anergized T cells form altered immunological synapses in vitro. American Journal of Transplantation. 6: 2572-2579. PMID 16952297 DOI: 10.1111/J.1600-6143.2006.01517.X  0.509
2006 Yachi PP, Ampudia J, Zal T, Gascoigne NR. Altered peptide ligands induce delayed CD8-T cell receptor interaction--a role for CD8 in distinguishing antigen quality. Immunity. 25: 203-11. PMID 16872849 DOI: 10.1016/J.Immuni.2006.05.015  0.538
2006 Bosco N, Hung HC, Pasqual N, Jouvin-Marche E, Marche PN, Gascoigne NR, Ceredig R. Role of the T cell receptor alpha chain in the development and phenotype of naturally arising CD4+CD25+ T cells. Molecular Immunology. 43: 246-54. PMID 16199261 DOI: 10.1016/J.Molimm.2005.02.002  0.494
2005 Yachi PP, Ampudia J, Gascoigne NR, Zal T. Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse. Nature Immunology. 6: 785-92. PMID 15980863 DOI: 10.1038/Ni1220  0.463
2005 Lin MY, Zal T, Ch'en IL, Gascoigne NR, Hedrick SM. A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase II in T cells: from activation to unresponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 174: 5583-92. PMID 15843557 DOI: 10.4049/Jimmunol.174.9.5583  0.475
2005 Niederberger N, Buehler LK, Ampudia J, Gascoigne NR. Thymocyte stimulation by anti-TCR-beta, but not by anti-TCR-alpha, leads to induction of developmental transcription program. Journal of Leukocyte Biology. 77: 830-41. PMID 15661827 DOI: 10.1189/Jlb.1004608  0.441
2004 Gronski MA, Boulter JM, Moskophidis D, Nguyen LT, Holmberg K, Elford AR, Deenick EK, Kim HO, Penninger JM, Odermatt B, Gallimore A, Gascoigne NR, Ohashi PS. TCR affinity and negative regulation limit autoimmunity. Nature Medicine. 10: 1234-9. PMID 15467726 DOI: 10.1038/Nm1114  0.503
2004 Zal T, Gascoigne NR. Using live FRET imaging to reveal early protein-protein interactions during T cell activation. Current Opinion in Immunology. 16: 418-27. PMID 15245734 DOI: 10.1016/J.Coi.2004.05.019  0.374
2004 Santori FR, Holmberg K, Ostrov D, Gascoigne NR, Vukmanović S. Distinct footprints of TCR engagement with highly homologous ligands. Journal of Immunology (Baltimore, Md. : 1950). 172: 7466-75. PMID 15187125 DOI: 10.4049/Jimmunol.172.12.7466  0.564
2004 Gascoigne NR, Zal T. Molecular interactions at the T cell-antigen-presenting cell interface. Current Opinion in Immunology. 16: 114-9. PMID 14734119 DOI: 10.1016/J.Coi.2003.11.008  0.524
2003 Holmberg K, Mariathasan S, Ohteki T, Ohashi PS, Gascoigne NR. TCR binding kinetics measured with MHC class I tetramers reveal a positive selecting peptide with relatively high affinity for TCR. Journal of Immunology (Baltimore, Md. : 1950). 171: 2427-34. PMID 12928390 DOI: 10.4049/Jimmunol.171.5.2427  0.459
2003 Niederberger N, Holmberg K, Alam SM, Sakati W, Naramura M, Gu H, Gascoigne NR. Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl. Journal of Immunology (Baltimore, Md. : 1950). 170: 4557-63. PMID 12707333 DOI: 10.4049/Jimmunol.170.9.4557  0.411
2003 Sim BC, Holmberg K, Sidobre S, Naidenko O, Niederberger N, Marine SD, Kronenberg M, Gascoigne NR. Surprisingly minor influence of TRAV11 (Valpha14) polymorphism on NK T-receptor mCD1/alpha-galactosylceramide binding kinetics. Immunogenetics. 54: 874-83. PMID 12671739 DOI: 10.1007/S00251-002-0532-Y  0.513
2003 Alam SM, Gascoigne NR. Binding kinetics of superantigen with TCR and MHC class II. Methods in Molecular Biology (Clifton, N.J.). 214: 65-85. PMID 12489455 DOI: 10.1385/1-59259-367-4:065  0.321
2002 Sidobre S, Naidenko OV, Sim BC, Gascoigne NR, Garcia KC, Kronenberg M. The V alpha 14 NKT cell TCR exhibits high-affinity binding to a glycolipid/CD1d complex. Journal of Immunology (Baltimore, Md. : 1950). 169: 1340-8. PMID 12133957 DOI: 10.4049/Jimmunol.169.3.1340  0.37
2002 Huang J, Lo PF, Zal T, Gascoigne NR, Smith BA, Levin SD, Grey HM. CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse. Proceedings of the National Academy of Sciences of the United States of America. 99: 9369-73. PMID 12077322 DOI: 10.1073/Pnas.142298399  0.526
2002 Zal T, Zal MA, Gascoigne NR. Inhibition of T cell receptor-coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse. Immunity. 16: 521-34. PMID 11970876 DOI: 10.1016/S1074-7613(02)00301-1  0.503
2002 Gascoigne NR. T-cell differentiation: MHC class I's sweet tooth lost on maturity. Current Biology : Cb. 12: R99-R101. PMID 11839290 DOI: 10.1016/S0960-9822(02)00671-1  0.506
2002 McGuire MV, Suthipinijtham P, Gascoigne NR. The mouse Supt16h/Fact140 gene, encoding part of the FACT chromatin transcription complex, maps close to Tcra and is highly expressed in thymus. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 12: 664-7. PMID 11471063 DOI: 10.1007/S003350020036  0.325
2001 Gascoigne NR, Zal T, Alam SM. T-cell receptor binding kinetics in T-cell development and activation. Expert Reviews in Molecular Medicine. 2001: 1-17. PMID 14987373 DOI: 10.1017/S1462399401002502  0.517
2001 Gascoigne NR. Positive selection in a Schnurri. Nature Immunology. 2: 989-91. PMID 11685218 DOI: 10.1038/Ni1101-989  0.301
2001 Rosette C, Werlen G, Daniels MA, Holman PO, Alam SM, Travers PJ, Gascoigne NR, Palmer E, Jameson SC. The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model. Immunity. 15: 59-70. PMID 11485738 DOI: 10.1016/S1074-7613(01)00173-X  0.727
2000 Gascoigne NR, Alam SM, Lin CM, McGuire MV, Marine S, Niederberger N, Redpath S, Sim BC, Travers PJ, Yachi P, Zal MA, Zal T. T cell receptor binding kinetics and special role of Valpha in T cell development and activation. Immunologic Research. 21: 225-31. PMID 10852121 DOI: 10.1385/Ir:21:2-3:225  0.56
1999 Alam SM, Davies GM, Lin CM, Zal T, Nasholds W, Jameson SC, Hogquist KA, Gascoigne NR, Travers PJ. Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands. Immunity. 10: 227-37. PMID 10072075 DOI: 10.1016/S1074-7613(00)80023-0  0.606
1998 Sim BC, Lo D, Gascoigne NR. Preferential expression of TCR V alpha regions in CD4/CD8 subsets: class discrimination or co-receptor recognition? Immunology Today. 19: 276-82. PMID 9639993 DOI: 10.1016/S0167-5699(98)01257-2  0.494
1998 Sim BC, Aftahi N, Reilly C, Bogen B, Schwartz RH, Gascoigne NR, Lo D. Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus. Current Biology : Cb. 8: 701-4. PMID 9637921 DOI: 10.1016/S0960-9822(98)70276-3  0.491
1997 Wung JL, Gascoigne NR. Selection of phage-displayed superantigen by binding to cell-surface MHC class II. Journal of Immunological Methods. 204: 33-41. PMID 9202707 DOI: 10.1016/S0022-1759(97)00038-0  0.412
1997 Wung JL, Gascoigne NR. Corrigendum to ``Selection of phage-displayed superantigen by binding to cell-surface MHC class II'' [J. Immunol. Methods 204 (1997) 33–41] Journal of Immunological Methods. 210: 251. DOI: 10.1016/S0022-1759(97)10038-2  0.355
1996 Sim BC, Zerva L, Greene MI, Gascoigne NR. Control of MHC restriction by TCR Valpha CDR1 and CDR2. Science (New York, N.Y.). 273: 963-6. PMID 8688082 DOI: 10.1126/Science.273.5277.963  0.463
1996 Alam SM, Travers PJ, Wung JL, Nasholds W, Redpath S, Jameson SC, Gascoigne NR. T-cell-receptor affinity and thymocyte positive selection. Nature. 381: 616-20. PMID 8637599 DOI: 10.1038/381616A0  0.658
1995 Alam SM, Crispe IN, Gascoigne NR. Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation. Immunity. 3: 449-58. PMID 7584136 DOI: 10.1016/1074-7613(95)90174-4  0.394
1995 Alam SM, Sim BC, Gascoigne NR. Selection of TCR V alpha by MHC class II predicts superantigen reactivity. International Immunology. 7: 1311-8. PMID 7495738 DOI: 10.1093/Intimm/7.8.1311  0.441
1993 Gascoigne NR. Interaction of the T cell receptor with bacterial superantigens. Seminars in Immunology. 5: 13-21. PMID 8467090 DOI: 10.1006/Smim.1993.1003  0.528
1993 Irwin MJ, Gascoigne NR. Interplay between superantigens and the immune system. Journal of Leukocyte Biology. 54: 495-503. PMID 8228628 DOI: 10.1002/Jlb.54.5.495  0.512
1992 Pontzer CH, Irwin MJ, Gascoigne NR, Johnson HM. T-cell antigen receptor binding sites for the microbial superantigen staphylococcal enterotoxin A. Proceedings of the National Academy of Sciences of the United States of America. 89: 7727-31. PMID 1502191 DOI: 10.1073/Pnas.89.16.7727  0.407
1992 Nakajima PB, Di Vincenzo JP, Jameson SC, Gascoigne NR. Chromosome 14 in B10.A(18R) mice is recombinant and includes Tcra-Va alleles. Immunogenetics. 35: 190-8. PMID 1371499 DOI: 10.1007/Bf00185113  0.539
1991 Gahm SJ, Fowlkes BJ, Jameson SC, Gascoigne NR, Cotterman MM, Kanagawa O, Schwartz RH, Matis LA. Profound alteration in an alpha beta T-cell antigen receptor repertoire due to polymorphism in the first complementarity-determining region of the beta chain. Proceedings of the National Academy of Sciences of the United States of America. 88: 10267-71. PMID 1835090 DOI: 10.1073/Pnas.88.22.10267  0.592
1991 Gascoigne NR, Ames KT. Direct binding of secreted T-cell receptor beta chain to superantigen associated with class II major histocompatibility complex protein. Proceedings of the National Academy of Sciences of the United States of America. 88: 613-6. PMID 1824876 DOI: 10.1073/Pnas.88.2.613  0.464
1991 Jameson SC, Nakajima PB, Brooks JL, Heath W, Kanagawa O, Gascoigne NR. The T cell receptor V alpha 11 gene family. Analysis of allelic sequence polymorphism and demonstration of J alpha region-dependent recognition by allele-specific antibodies. Journal of Immunology (Baltimore, Md. : 1950). 147: 3185-93. PMID 1717591  0.505
1990 Jameson SC, Kaye J, Gascoigne NR. A T cell receptor V alpha region selectively expressed in CD4+ cells. Journal of Immunology (Baltimore, Md. : 1950). 145: 1324-31. PMID 1696594  0.615
1989 Kaye J, Hsu ML, Sauron ME, Jameson SC, Gascoigne NR, Hedrick SM. Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature. 341: 746-9. PMID 2571940 DOI: 10.1038/341746A0  0.701
1987 Davis MM, Gascoigne NR, Lindsten T, Goodnow C, Chien Y. Murine T-cell receptor genes Advances in Experimental Medicine and Biology. 213: 13-17. PMID 3498293 DOI: 10.1007/978-1-4684-5323-2_2  0.499
1987 Gascoigne NR, Goodnow CC, Dudzik KI, Oi VT, Davis MM. Secretion of a chimeric T-cell receptor-immunoglobulin protein. Proceedings of the National Academy of Sciences of the United States of America. 84: 2936-40. PMID 3472243 DOI: 10.1073/Pnas.84.9.2936  0.509
1986 Davis MM, Lindsten T, Gascoigne NR, Goodnow C, Chien YH. T-cell receptor gene structure and function. Cellular Immunology. 99: 24-8. PMID 3489561 DOI: 10.1016/0008-8749(86)90211-X  0.511
1986 Davis MM, Lindsten T, Gascoigne NR, Goodnow C, Chien YH. Paradigm regained: similarities and differences between T cell receptor and immunoglobulin genes Biochemical Society Symposia. 51: 205-209. PMID 3101698  0.37
1986 Gascoigne NR, Waters S, Elliott JF, Victor-Kobrin C, Goodnow C, Davis MM, Bona CA. Expression of T cell receptor genes in an antigen-specific hybridoma and radiation-induced variants. The Journal of Experimental Medicine. 164: 113-30. PMID 2425026 DOI: 10.1084/Jem.164.1.113  0.477
1985 Becker DM, Pattern P, Chien Y, Yokota T, Eshhar Z, Giedlin M, Gascoigne NR, Goodnow C, Wolf R, Arai K. Variability and repertoire size of T-cell receptor V alpha gene segments. Nature. 317: 430-4. PMID 2995827 DOI: 10.1038/317430A0  0.362
1985 Hedrick SM, Germain RN, Bevan MJ, Dorf M, Engel I, Fink P, Gascoigne N, Heber-Katz E, Kapp J, Kaufmann Y. Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsets. Proceedings of the National Academy of Sciences of the United States of America. 82: 531-5. PMID 2578667 DOI: 10.1073/Pnas.82.2.531  0.494
1984 Gascoigne NR, Crispe IN. Differential expression of the repertoire in in vitro and in vivo responses to minor alloantigens. Immunogenetics. 19: 511-7. PMID 6610635 DOI: 10.1007/Bf00403442  0.373
1984 Crispe IN, Gascoigne NR. Computer-assisted analysis of in vivo cytotoxic T cell responses. Journal of Immunological Methods. 64: 91-8. PMID 6606000 DOI: 10.1016/0022-1759(83)90387-3  0.393
1984 Gascoigne NR, Chien Y, Becker DM, Kavaler J, Davis MM. Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Nature. 310: 387-91. PMID 6336329 DOI: 10.1038/310387A0  0.336
1984 Chien YH, Gascoigne NR, Kavaler J, Lee NE, Davis MM. Somatic recombination in a murine T-cell receptor gene. Nature. 309: 322-6. PMID 6328306 DOI: 10.1038/309322A0  0.447
1984 Owens T, Czitrom AA, Gascoigne NR, Crispe IN, Ratcliffe MJ, Lai PK, Mitchison NA. The presentation of cell surface alloantigens to T cells. Immunobiology. 168: 189-201. PMID 6241598 DOI: 10.1016/S0171-2985(84)80110-2  0.451
1984 Gascoigne NR. Suppression of the cytotoxic T cell response to minor alloantigens in vivo. II. Fine specificity of suppressor T cells and lack of restriction by immunoglobulin heavy chain-linked gene products. European Journal of Immunology. 14: 677-80. PMID 6235118 DOI: 10.1002/Eji.1830140717  0.51
1984 Gascoigne NR, Crispe IN. Suppression of the cytotoxic T cell response to minor alloantigens in vivo. Linked recognition by suppressor T cells. European Journal of Immunology. 14: 210-5. PMID 6200331 DOI: 10.1002/Eji.1830140303  0.478
1984 Gascoigne NR, Lai PK. T helper cell lines that augment in vivo cytotoxic T-cell responses to minor alloantigens. Cellular Immunology. 83: 302-12. PMID 6198100 DOI: 10.1016/0008-8749(84)90309-5  0.443
1984 Davis MM, Chien YH, Gascoigne NR, Hedrick SM. A murine T cell receptor gene complex: isolation, structure and rearrangement Immunological Reviews. 81: 235-258. PMID 6096259 DOI: 10.1111/J.1600-065X.1984.Tb01113.X  0.449
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