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Lauren G. Holden, Ph.D. - Publications

Affiliations: 
2011 Molecular Biology University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology, Virology Biology
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ngo T, Stephens BS, Gustavsson M, Holden LG, Abagyan R, Handel TM, Kufareva I. Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity. Plos Biology. 18: e3000656. PMID 32271748 DOI: 10.1371/Journal.Pbio.3000656  0.363
2017 Kumar R, Ozorowski G, Kumar V, Holden LG, Shrivastava T, Patil S, Deshpande S, Ward AB, Bhattacharya J. Characterization of a stable HIV-1 B/C recombinant, soluble and trimeric envelope glycoprotein (Env) highly resistant to CD4-induced conformational changes. The Journal of Biological Chemistry. PMID 28743743 DOI: 10.1074/Jbc.M117.803056  0.311
2016 Kufareva I, Gustavsson M, Holden LG, Qin L, Zheng Y, Handel TM. Disulfide Trapping for Modeling and Structure Determination of Receptor: Chemokine Complexes. Methods in Enzymology. 570: 389-420. PMID 26921956 DOI: 10.1016/Bs.Mie.2015.12.001  0.398
2016 Gustavsson M, Zheng Y, Qin L, Holden LG, Kufareva I, Handel TM. Abstract A168: Towards an understanding of the structural basis of CXCR7 ligand binding and signaling Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A168  0.438
2015 Qin L, Kufareva I, Holden LG, Wang C, Zheng Y, Zhao C, Fenalti G, Wu H, Han GW, Cherezov V, Abagyan R, Stevens RC, Handel TM. Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine. Science (New York, N.Y.). 347: 1117-22. PMID 25612609 DOI: 10.1126/Science.1261064  0.498
2014 Kufareva I, Stephens BS, Holden LG, Qin L, Zhao C, Kawamura T, Abagyan R, Handel TM. Stoichiometry and geometry of the CXC chemokine receptor 4 complex with CXC ligand 12: molecular modeling and experimental validation. Proceedings of the National Academy of Sciences of the United States of America. 111: E5363-72. PMID 25468967 DOI: 10.1073/Pnas.1417037111  0.386
2008 Holden LG, Prochnow C, Chang YP, Bransteitter R, Chelico L, Sen U, Stevens RC, Goodman MF, Chen XS. Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications. Nature. 456: 121-4. PMID 18849968 DOI: 10.1038/Nature07357  0.368
2008 Fletcher RJ, Shen J, Holden LG, Chen XS. Identification of amino acids important for the biochemical activity of Methanothermobacter thermautotrophicus MCM. Biochemistry. 47: 9981-6. PMID 18754676 DOI: 10.1021/Bi800032T  0.552
2008 Wang G, Klein MG, Tokonzaba E, Zhang Y, Holden LG, Chen XS. The structure of a DnaB-family replicative helicase and its interactions with primase. Nature Structural & Molecular Biology. 15: 94-100. PMID 18157148 DOI: 10.1038/Nsmb1356  0.651
2006 Perry JJ, Yannone SM, Holden LG, Hitomi C, Asaithamby A, Han S, Cooper PK, Chen DJ, Tainer JA. WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nature Structural & Molecular Biology. 13: 414-22. PMID 16622405 DOI: 10.1038/nsmb1088  0.514
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