| Year |
Citation |
Score |
| 2020 |
Alsanafi M, Kelly SL, McNaughton M, Merrill AH, Pyne NJ, Pyne S. The regulation of p53, p38 MAPK, JNK and XBP-1s by sphingosine kinases in human embryonic kidney cells. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158631. PMID 31954175 DOI: 10.1016/J.Bbalip.2020.158631 |
0.322 |
|
| 2019 |
Wan J, Li J, Bandyopadhyay S, Kelly SL, Xiang Y, Zhang J, Merrill A, Duan J. Analysis of 1-deoxysphingoid bases and their N-acyl-metabolites, and exploration of their occurrence in some food materials. Journal of Agricultural and Food Chemistry. PMID 31638789 DOI: 10.1021/Acs.Jafc.9B05708 |
0.309 |
|
| 2019 |
Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, ... ... Merrill AH, et al. Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology. PMID 31636468 DOI: 10.1038/S41590-019-0504-0 |
0.378 |
|
| 2019 |
Riley RT, Merrill AH. Ceramide synthase inhibition by fumonisins: a perfect storm of perturbed sphingolipid metabolism, signaling and disease. Journal of Lipid Research. PMID 31048407 DOI: 10.1194/Jlr.S093815 |
0.389 |
|
| 2018 |
Tidhar R, Zelnik ID, Volpert G, Ben-Dor S, Kelly S, Merrill AH, Futerman AH. Eleven residues determine the acyl chain specificity of ceramide synthases. The Journal of Biological Chemistry. PMID 29632068 DOI: 10.1074/Jbc.Ra118.001936 |
0.336 |
|
| 2017 |
Saroha A, Pewzner-Jung Y, Ferreira NS, Sharma P, Jouan Y, Kelly SL, Feldmesser E, Merrill AH, Trottein F, Paget C, Lang KS, Futerman AH. Critical Role for Very-Long Chain Sphingolipids in Invariant Natural Killer T Cell Development and Homeostasis. Frontiers in Immunology. 8: 1386. PMID 29163475 DOI: 10.3389/Fimmu.2017.01386 |
0.336 |
|
| 2017 |
Dasari SK, Bialik S, Levin-Zaidman S, Levin-Salomon V, Merrill AH, Futerman AH, Kimchi A. Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death. Cell Death and Differentiation. PMID 28574511 DOI: 10.1038/Cdd.2017.80 |
0.338 |
|
| 2017 |
Ferreira NS, Engelsby H, Neess D, Kelly SL, Volpert G, Merrill AH, Futerman AH, Faergeman NJ. Regulation of very-long acyl chain ceramide synthesis by Acyl-CoA binding protein. The Journal of Biological Chemistry. PMID 28320857 DOI: 10.1074/Jbc.M117.785345 |
0.378 |
|
| 2017 |
Volpert G, Ben-Dor S, Tarcic O, Duan J, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Oxidative stress elicited by modifying the ceramide acyl chain length reduces the rate of clathrin-mediated endocytosis. Journal of Cell Science. PMID 28280117 DOI: 10.1242/Jcs.199968 |
0.307 |
|
| 2017 |
Deevska GM, Dotson PP, Karakashian AA, Isaac G, Wrona M, Kelly SB, Merrill AH, Nikolova-Karakashian MN. Novel interconnections in lipid metabolism revealed by overexpression of sphingomyelin synthase-1. The Journal of Biological Chemistry. PMID 28087695 DOI: 10.1074/Jbc.M116.751602 |
0.395 |
|
| 2016 |
Vardi A, Zigdon H, Meshcheriakova A, Klein AD, Yaacobi C, Eilam R, Kenwood BM, Rahim AA, Massaro G, Merrill AH, Vitner EB, Futerman AH. Delineating pathological pathways in a chemically-induced mouse model of Gaucher disease. The Journal of Pathology. PMID 27234572 DOI: 10.1002/Path.4751 |
0.731 |
|
| 2015 |
Park W, Park J, Merrill AH, Storch J, Pewzner-Jung Y, Futerman AH. Corrigendum to “Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length” [Mol. Cell Biol. Lipids 1841(12) (2014) 1754–1766] Biochimica Et Biophysica Acta (Bba) - Molecular and Cell Biology of Lipids. 1851: 996. DOI: 10.1016/J.Bbalip.2015.03.002 |
0.338 |
|
| 2014 |
Jiménez-Rojo N, Sot J, Busto JV, Shaw WA, Duan J, Merrill AH, Alonso A, Goñi FM. Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cells. Biophysical Journal. 107: 2850-9. PMID 25517151 DOI: 10.1016/J.Bpj.2014.10.010 |
0.343 |
|
| 2014 |
Park WJ, Park JW, Merrill AH, Storch J, Pewzner-Jung Y, Futerman AH. Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length. Biochimica Et Biophysica Acta. 1841: 1754-66. PMID 25241943 DOI: 10.1016/J.Bbalip.2014.09.009 |
0.314 |
|
| 2014 |
Pinto SN, Laviad EL, Stiban J, Kelly SL, Merrill AH, Prieto M, Futerman AH, Silva LC. Changes in membrane biophysical properties induced by sphingomyelinase depend on the sphingolipid N-acyl chain. Journal of Lipid Research. 55: 53-61. PMID 24163422 DOI: 10.1194/Jlr.M042002 |
0.312 |
|
| 2013 |
Shibata N, Carlin AF, Spann NJ, Saijo K, Morello CS, McDonald JG, Romanoski CE, Maurya MR, Kaikkonen MU, Lam MT, Crotti A, Reichart D, Fox JN, Quehenberger O, Raetz CR, ... ... Merrill AH, et al. 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. The Journal of Biological Chemistry. 288: 35812-23. PMID 24189069 DOI: 10.1074/Jbc.M113.519637 |
0.321 |
|
| 2013 |
Park WJ, Park JW, Erez-Roman R, Kogot-Levin A, Bame JR, Tirosh B, Saada A, Merrill AH, Pewzner-Jung Y, Futerman AH. Protection of a ceramide synthase 2 null mouse from drug-induced liver injury: role of gap junction dysfunction and connexin 32 mislocalization. The Journal of Biological Chemistry. 288: 30904-16. PMID 24019516 DOI: 10.1074/Jbc.M112.448852 |
0.326 |
|
| 2013 |
Zigdon H, Kogot-Levin A, Park JW, Goldschmidt R, Kelly S, Merrill AH, Scherz A, Pewzner-Jung Y, Saada A, Futerman AH. Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain. The Journal of Biological Chemistry. 288: 4947-56. PMID 23283968 DOI: 10.1074/Jbc.M112.402719 |
0.334 |
|
| 2013 |
Merrill AH. Thematic review series on the living history of lipids Journal of Lipid Research. 54: 2945. DOI: 10.1194/Jlr.E044164 |
0.336 |
|
| 2012 |
Spann NJ, Garmire LX, McDonald JG, Myers DS, Milne SB, Shibata N, Reichart D, Fox JN, Shaked I, Heudobler D, Raetz CR, Wang EW, Kelly SL, Sullards MC, Murphy RC, ... Merrill AH, et al. Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell. 151: 138-52. PMID 23021221 DOI: 10.1016/J.Cell.2012.06.054 |
0.342 |
|
| 2012 |
Lucki NC, Li D, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. Molecular and Cellular Biology. 32: 4419-31. PMID 22927646 DOI: 10.1128/Mcb.00378-12 |
0.315 |
|
| 2012 |
Laviad EL, Kelly S, Merrill AH, Futerman AH. Modulation of ceramide synthase activity via dimerization. The Journal of Biological Chemistry. 287: 21025-33. PMID 22539345 DOI: 10.1074/Jbc.M112.363580 |
0.331 |
|
| 2012 |
Hagen-Euteneuer N, Lütjohann D, Park H, Merrill AH, van Echten-Deckert G. Sphingosine 1-phosphate (S1P) lyase deficiency increases sphingolipid formation via recycling at the expense of de novo biosynthesis in neurons. The Journal of Biological Chemistry. 287: 9128-36. PMID 22291021 DOI: 10.1074/Jbc.M111.302380 |
0.361 |
|
| 2012 |
Lucki NC, Bandyopadhyay S, Wang E, Merrill AH, Sewer MB. Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression. Molecular Endocrinology (Baltimore, Md.). 26: 228-43. PMID 22261821 DOI: 10.1210/Me.2011-1150 |
0.359 |
|
| 2012 |
Tidhar R, Ben-Dor S, Wang E, Kelly S, Merrill AH, Futerman AH. Acyl chain specificity of ceramide synthases is determined within a region of 150 residues in the Tram-Lag-CLN8 (TLC) domain. The Journal of Biological Chemistry. 287: 3197-206. PMID 22144673 DOI: 10.1074/Jbc.M111.280271 |
0.309 |
|
| 2011 |
Haynes CA, Allegood JC, Wang EW, Kelly SL, Sullards MC, Merrill AH. Factors to consider in using [U- 13C]palmitate for analysis of sphingolipid biosynthesis by tandem mass spectrometry Journal of Lipid Research. 52: 1583-1594. PMID 21586681 DOI: 10.1194/Jlr.D015586 |
0.305 |
|
| 2011 |
Momin AA, Park H, Portz BJ, Haynes CA, Shaner RL, Kelly SL, Jordan IK, Merrill AH. A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences. Journal of Lipid Research. 52: 1073-83. PMID 21415121 DOI: 10.1194/Jlr.M010454 |
0.315 |
|
| 2011 |
Symolon H, Bushnev A, Peng Q, Ramaraju H, Mays SG, Allegood JC, Pruett ST, Sullards MC, Dillehay DL, Liotta DC, Merrill AH. Enigmol: A novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer Molecular Cancer Therapeutics. 10: 648-657. PMID 21398423 DOI: 10.1158/1535-7163.Mct-10-0754 |
0.316 |
|
| 2011 |
Quo CF, Moffitt RA, Merrill AH, Wang MD. Adaptive control model reveals systematic feedback and key molecules in metabolic pathway regulation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 169-82. PMID 21314456 DOI: 10.1089/Cmb.2010.0215 |
0.307 |
|
| 2011 |
Gupta S, Maurya MR, Merrill AH, Glass CK, Subramaniam S. Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism. Bmc Systems Biology. 5: 26. PMID 21303545 DOI: 10.1186/1752-0509-5-26 |
0.378 |
|
| 2010 |
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH, Sullards MC, Wang E, Murphy RC, Raetz CR, et al. A mouse macrophage lipidome. The Journal of Biological Chemistry. 285: 39976-85. PMID 20923771 DOI: 10.1074/Jbc.M110.182915 |
0.36 |
|
| 2010 |
Sims K, Haynes CA, Kelly S, Allegood JC, Wang E, Momin A, Leipelt M, Reichart D, Glass CK, Sullards MC, Merrill AH. Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. The Journal of Biological Chemistry. 285: 38568-79. PMID 20876532 DOI: 10.1074/Jbc.M110.170621 |
0.401 |
|
| 2010 |
Chen Y, Liu Y, Sullards MC, Merrill AH. An introduction to sphingolipid metabolism and analysis by new technologies. Neuromolecular Medicine. 12: 306-19. PMID 20680704 DOI: 10.1007/S12017-010-8132-8 |
0.317 |
|
| 2010 |
Quehenberger O, Armando AM, Brown AH, Milne SB, Myers DS, Merrill AH, Bandyopadhyay S, Jones KN, Kelly S, Shaner RL, Sullards CM, Wang E, Murphy RC, Barkley RM, Leiker TJ, et al. Lipidomics reveals a remarkable diversity of lipids in human plasma. Journal of Lipid Research. 51: 3299-305. PMID 20671299 DOI: 10.1194/Jlr.M009449 |
0.308 |
|
| 2010 |
Andreyev AY, Fahy E, Guan Z, Kelly S, Li X, McDonald JG, Milne S, Myers D, Park H, Ryan A, Thompson BM, Wang E, Zhao Y, Brown HA, Merrill AH, et al. Subcellular organelle lipidomics in TLR-4-activated macrophages. Journal of Lipid Research. 51: 2785-97. PMID 20574076 DOI: 10.1194/Jlr.M008748 |
0.351 |
|
| 2010 |
Pewzner-Jung Y, Brenner O, Braun S, Laviad EL, Ben-Dor S, Feldmesser E, Horn-Saban S, Amann-Zalcenstein D, Raanan C, Berkutzki T, Erez-Roman R, Ben-David O, Levy M, Holzman D, Park H, ... ... Merrill AH, et al. A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. The Journal of Biological Chemistry. 285: 10911-23. PMID 20110366 DOI: 10.1074/Jbc.M109.077610 |
0.396 |
|
| 2010 |
Pewzner-Jung Y, Park H, Laviad EL, Silva LC, Lahiri S, Stiban J, Erez-Roman R, Brügger B, Sachsenheimer T, Wieland F, Prieto M, Merrill AH, Futerman AH. A critical role for ceramide synthase 2 in liver homeostasis: I. alterations in lipid metabolic pathways. The Journal of Biological Chemistry. 285: 10902-10. PMID 20110363 DOI: 10.1074/Jbc.M109.077594 |
0.411 |
|
| 2010 |
Yin J, Miyazaki K, Shaner RL, Merrill AH, Kannagi R. Altered sphingolipid metabolism induced by tumor hypoxia - New vistas in glycolipid tumor markers Febs Letters. 584: 1872-1878. PMID 19913543 DOI: 10.1016/J.Febslet.2009.11.019 |
0.307 |
|
| 2010 |
Park H, Haynes CA, Nairn AV, Kulik M, Dalton S, Moremen K, Merrill AH. Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. Journal of Lipid Research. 51: 480-9. PMID 19786568 DOI: 10.1194/Jlr.M000984 |
0.324 |
|
| 2010 |
Reinartz A, Haynes CA, Knuechel R, Merrill AH, Gassler N. Lipid-Induced Up-Regulation of Acyl-CoA Synthetase 5 Promotes Apoptosis in Human Hepatoctes Biophysical Journal. 98: 466a. DOI: 10.1016/J.Bpj.2009.12.2531 |
0.385 |
|
| 2009 |
Momin AA, Park H, Allegood JC, Leipelt M, Kelly SL, Merrill AH, Hanada K. Characterization of mutant serine palmitoyltransferase 1 in LY-B cells. Lipids. 44: 725-32. PMID 19536577 DOI: 10.1007/S11745-009-3316-4 |
0.321 |
|
| 2009 |
Goldfinger M, Laviad EL, Hadar R, Shmuel M, Dagan A, Park H, Merrill AH, Ringel I, Futerman AH, Tirosh B. De novo ceramide synthesis is required for N-linked glycosylation in plasma cells. Journal of Immunology (Baltimore, Md. : 1950). 182: 7038-47. PMID 19454701 DOI: 10.4049/Jimmunol.0802990 |
0.36 |
|
| 2009 |
Hu W, Bielawski J, Samad F, Merrill AH, Cowart LA. Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity Journal of Lipid Research. 50: 1852-1862. PMID 19369694 DOI: 10.1194/Jlr.M800635-Jlr200 |
0.335 |
|
| 2009 |
Coward J, Ambrosini G, Musi E, Truman JP, Haimovitz-Friedman A, Allegood JC, Wang E, Merrill AH, Schwartz GK. Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway. Autophagy. 5: 184-93. PMID 19098447 DOI: 10.4161/Auto.5.2.7361 |
0.352 |
|
| 2009 |
Zitomer NC, Mitchell T, Voss KA, Bondy GS, Pruett ST, Garnier-Amblard EC, Liebeskind LS, Park H, Wang E, Sulllards MC, Merrill AH, Riley RT. Ceramide synthase inhibition by fumonisin B1 causes accumulation of 1-deoxysphinganine. A novel category of bioactive 1-deoxysphingoid bases and 1-deoxydihydroceramides biosynthesized by mammalian cell lines and animals Journal of Biological Chemistry. 284: 4786-4795. PMID 19095642 DOI: 10.1074/Jbc.M808798200 |
0.384 |
|
| 2009 |
Deevska GM, Rozenova KA, Giltiay NV, Chambers MA, White J, Boyanovsky BB, Wei J, Daugherty A, Smart EJ, Reid MB, Merrill AH, Nikolova-Karakashian M. Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice. The Journal of Biological Chemistry. 284: 8359-68. PMID 19074137 DOI: 10.1074/Jbc.M807800200 |
0.324 |
|
| 2009 |
Merrill AH, Stokes TH, Momin A, Park H, Portz BJ, Kelly S, Wang E, Sullards MC, Wang MD. Sphingolipidomics: a valuable tool for understanding the roles of sphingolipids in biology and disease. Journal of Lipid Research. 50: S97-102. PMID 19029065 DOI: 10.1194/Jlr.R800073-Jlr200 |
0.312 |
|
| 2008 |
Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC. N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing. Molecular Cancer Therapeutics. 7: 2967-76. PMID 18790777 DOI: 10.1158/1535-7163.Mct-08-0549 |
0.362 |
|
| 2008 |
Machesky NJ, Zhang G, Raghavan B, Zimmerman P, Kelly SL, Merrill AH, Waldman WJ, Van Brocklyn JR, Trgovcich J. Human cytomegalovirus regulates bioactive sphingolipids. The Journal of Biological Chemistry. 283: 26148-60. PMID 18644793 DOI: 10.1074/Jbc.M710181200 |
0.354 |
|
| 2008 |
Pruett ST, Bushnev A, Hagedorn K, Adiga M, Haynes CA, Sullards MC, Liotta DC, Merrill AH. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols Journal of Lipid Research. 49: 1621-1639. PMID 18499644 DOI: 10.1194/Jlr.R800012-Jlr200 |
0.319 |
|
| 2008 |
Haynes CA, Allegood JC, Sims K, Wang EW, Sullards MC, Merrill AH. Quantitation of fatty acyl-coenzyme As in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry Journal of Lipid Research. 49: 1113-1125. PMID 18287618 DOI: 10.1194/Jlr.D800001-Jlr200 |
0.354 |
|
| 2008 |
Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH, Futerman AH. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. The Journal of Biological Chemistry. 283: 5677-84. PMID 18165233 DOI: 10.1074/Jbc.M707386200 |
0.4 |
|
| 2008 |
Merrill A. Abstract ED01-02: Sphingolipid biodiversity and cancer: an endless source of surprises in cell regulation and novel strategies for cancer chemoprevention and chemotherapy Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Ed01-02 |
0.324 |
|
| 2008 |
Sims K, Fluke K, Symolon H, Zheng W, Munter E, Momin A, Pack C, Haynes C, Kelly S, Allegood J, Wang E, Merrill A. Abstract B102: Fenretinide induces lethal autophagy via a novel ensemble of life and death regulators: dihydroceramide and sphinganine versus sphinganine 1-phosphate Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B102 |
0.341 |
|
| 2007 |
Sullards MC, Allegood JC, Kelly S, Wang E, Haynes CA, Park H, Chen Y, Merrill AH. Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics. Methods in Enzymology. 432: 83-115. PMID 17954214 DOI: 10.1016/S0076-6879(07)32004-1 |
0.309 |
|
| 2007 |
Seiferlein M, Humpf HU, Voss KA, Sullards MC, Allegood JC, Wang E, Merrill AH. Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites Molecular Nutrition and Food Research. 51: 1120-1130. PMID 17729221 DOI: 10.1002/Mnfr.200700118 |
0.378 |
|
| 2007 |
Li D, Urs AN, Allegood J, Leon A, Merrill AH, Sewer MB. Cyclic AMP-stimulated interaction between steroidogenic factor 1 and diacylglycerol kinase theta facilitates induction of CYP17. Molecular and Cellular Biology. 27: 6669-85. PMID 17664281 DOI: 10.1128/Mcb.00355-07 |
0.32 |
|
| 2007 |
Morales PR, Dillehay DL, Moody SJ, Pallas DC, Pruett S, Allgood JC, Symolon H, Merrill AH. Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation. Drug and Chemical Toxicology. 30: 197-216. PMID 17613006 DOI: 10.1080/01480540701375018 |
0.307 |
|
| 2007 |
Rao RP, Yuan C, Allegood JC, Rawat SS, Edwards MB, Wang X, Merrill AH, Acharya U, Acharya JK. Ceramide transfer protein function is essential for normal oxidative stress response and lifespan. Proceedings of the National Academy of Sciences of the United States of America. 104: 11364-9. PMID 17592126 DOI: 10.1073/Pnas.0705049104 |
0.312 |
|
| 2007 |
Lamour NF, Stahelin RV, Wijesinghe DS, Maceyka M, Wang E, Allegood JC, Merrill AH, Cho W, Chalfant CE. Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis. Journal of Lipid Research. 48: 1293-304. PMID 17392267 DOI: 10.1194/Jlr.M700083-Jlr200 |
0.325 |
|
| 2007 |
Urs AN, Dammer E, Kelly S, Wang E, Merrill AH, Sewer MB. Steroidogenic factor-1 is a sphingolipid binding protein. Molecular and Cellular Endocrinology. 265: 174-8. PMID 17196738 DOI: 10.1016/J.Mce.2006.12.016 |
0.307 |
|
| 2007 |
Brimble SN, Sherrer ES, Uhl EW, Wang E, Kelly S, Merrill AH, Robins AJ, Schulz TC. The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency. Stem Cells (Dayton, Ohio). 25: 54-62. PMID 17008424 DOI: 10.1634/Stemcells.2006-0232 |
0.303 |
|
| 2007 |
Wei J, Wang E, Kelly S, Sullards C, Merrill A. Up‐regulation of de novo sphingolipid biosynthesis through serine palmitoyltransferease in RAW 264.7 cells upon Kdo2‐Lipid A treatment The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A240 |
0.324 |
|
| 2007 |
Liu Y, Haynes C, Allegood J, Kelly S, Wang E, Merrill A. Elevation Of Sphingoid Bases In Hek293 Cells Increases C18‐(Dihydro)Ceramide Biosynthesis Via Alteration Of LASS1 (Cers1) Expression, Activity And Subcellular Localization The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A237-B |
0.319 |
|
| 2006 |
Zheng W, Kollmeyer J, Symolon H, Momin A, Munter E, Wang E, Kelly S, Allegood JC, Liu Y, Peng Q, Ramaraju H, Sullards MC, Cabot M, Merrill AH. Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy. Biochimica Et Biophysica Acta. 1758: 1864-84. PMID 17052686 DOI: 10.1016/J.Bbamem.2006.08.009 |
0.372 |
|
| 2006 |
Dragusin M, Wehner S, Kelly S, Wang E, Merrill AH, Kalff JC, van Echten-Deckert G. Effects of sphingosine-1-phosphate and ceramide-1-phosphate on rat intestinal smooth muscle cells: implications for postoperative ileus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1930-2. PMID 16877527 DOI: 10.1096/Fj.05-5518Fje |
0.325 |
|
| 2006 |
Giussani P, Maceyka M, Le Stunff H, Mikami A, Lépine S, Wang E, Kelly S, Merrill AH, Milstien S, Spiegel S. Sphingosine-1-phosphate phosphohydrolase regulates endoplasmic reticulum-to-golgi trafficking of ceramide. Molecular and Cellular Biology. 26: 5055-69. PMID 16782891 DOI: 10.1128/Mcb.02107-05 |
0.356 |
|
| 2006 |
Curfman CL, Kirkland K, Merrill AH. Recent anticancer agents targeting sphingolipid pathways Expert Opinion On Therapeutic Patents. 16: 1129-1147. DOI: 10.1517/13543776.16.8.1129 |
0.339 |
|
| 2005 |
Maceyka M, Sankala H, Hait NC, Le Stunff H, Liu H, Toman R, Collier C, Zhang M, Satin LS, Merrill AH, Milstien S, Spiegel S. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism. The Journal of Biological Chemistry. 280: 37118-29. PMID 16118219 DOI: 10.1074/Jbc.M502207200 |
0.375 |
|
| 2005 |
Fahy E, Subramaniam S, Brown HA, Glass CK, Merrill AH, Murphy RC, Raetz CR, Russell DW, Seyama Y, Shaw W, Shimizu T, Spener F, van Meer G, VanNieuwenhze MS, White SH, et al. A comprehensive classification system for lipids. Journal of Lipid Research. 46: 839-61. PMID 15722563 DOI: 10.1194/Jlr.E400004-Jlr200 |
0.308 |
|
| 2004 |
Ozbay T, Merrill AH, Sewer MB. ACTH regulates steroidogenic gene expression and cortisol biosynthesis in the human adrenal cortex via sphingolipid metabolism. Endocrine Research. 30: 787-94. PMID 15666826 DOI: 10.1081/Erc-200044040 |
0.386 |
|
| 2004 |
Monick MM, Mallampalli RK, Bradford M, McCoy D, Gross TJ, Flaherty DM, Powers LS, Cameron K, Kelly S, Merrill AH, Hunninghake GW. Cooperative prosurvival activity by ERK and Akt in human alveolar macrophages is dependent on high levels of acid ceramidase activity. Journal of Immunology (Baltimore, Md. : 1950). 173: 123-35. PMID 15210766 DOI: 10.4049/Jimmunol.173.1.123 |
0.304 |
|
| 2004 |
Symolon H, Schmelz EM, Dillehay DL, Merrill AH. Dietary Soy Sphingolipids Suppress Tumorigenesis and Gene Expression in 1,2-Dimethylhydrazine-Treated CF1 Mice and ApcMin/+ Mice Journal of Nutrition. 134: 1157-1161. PMID 15113963 DOI: 10.1093/Jn/134.5.1157 |
0.313 |
|
| 2004 |
Dedov VN, Dedova IV, Merrill AH, Nicholson GA. Activity of partially inhibited serine palmitoyltransferase is sufficient for normal sphingolipid metabolism and viability of HSN1 patient cells. Biochimica Et Biophysica Acta. 1688: 168-75. PMID 14990347 DOI: 10.1016/J.Bbadis.2003.12.005 |
0.344 |
|
| 2004 |
Reiss U, Oskouian B, Zhou J, Gupta V, Sooriyakumaran P, Kelly S, Wang E, Merrill AH, Saba JD. Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. The Journal of Biological Chemistry. 279: 1281-90. PMID 14570870 DOI: 10.1074/Jbc.M309646200 |
0.365 |
|
| 2003 |
Riebeling C, Allegood JC, Wang E, Merrill AH, Futerman AH. Two Mammalian Longevity Assurance Gene (LAG1) Family Members, trh1 and trh4, Regulate Dihydroceramide Synthesis Using Different Fatty Acyl-CoA Donors Journal of Biological Chemistry. 278: 43452-43459. PMID 12912983 DOI: 10.1074/Jbc.M307104200 |
0.379 |
|
| 2003 |
Menaldino DS, Bushnev A, Sun A, Liotta DC, Symolon H, Desai K, Dillehay DL, Peng Q, Wang E, Allegood J, Trotman-Pruett S, Sullards MC, Merrill AH. Sphingoid bases and de novo ceramide synthesis: Enzymes involved, pharmacology and mechanisms of action Pharmacological Research. 47: 373-381. PMID 12676511 DOI: 10.1016/S1043-6618(03)00054-9 |
0.328 |
|
| 2002 |
Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill AH. Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1585: 188-192. PMID 12531553 DOI: 10.1016/S1388-1981(02)00340-2 |
0.387 |
|
| 2002 |
Patten Hitt E, DeLong MJ, Merrill AH. Benzo(a)pyrene activates extracellular signal-related and p38 mitogen-activated protein kinases in HT29 colon adenocarcinoma cells: involvement in NAD(P)H:quinone reductase activity and cell proliferation. Toxicology and Applied Pharmacology. 183: 160-7. PMID 12383707 DOI: 10.1006/Taap.2002.9483 |
0.313 |
|
| 2002 |
Venkataraman K, Riebeling C, Bodennec J, Riezman H, Allegood JC, Sullards MC, Merrill AH, Futerman AH. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. The Journal of Biological Chemistry. 277: 35642-9. PMID 12105227 DOI: 10.1074/Jbc.M205211200 |
0.401 |
|
| 2002 |
Merrill AH, Sandhoff K. Chapter 14 Sphingolipids: metabolism and cell signaling New Comprehensive Biochemistry. 36: 373-407. DOI: 10.1016/S0167-7306(02)36016-2 |
0.359 |
|
| 2001 |
Riley RT, Enongene E, Voss KA, Norred WP, Meredith FI, Sharma RP, Spitsbergen J, Williams DE, Carlson DB, Merrill AH. Sphingolipid perturbations as mechanisms for fumonisin carcinogenesis. Environmental Health Perspectives. 109: 301-8. PMID 11359699 DOI: 10.1289/Ehp.01109S2301 |
0.369 |
|
| 2001 |
Merrill AH, Sullards MC, Wang E, Voss KA, Riley RT. Sphingolipid metabolism: Roles in signal transduction and disruption by fumonisins Environmental Health Perspectives. 109: 283-289. PMID 11359697 DOI: 10.1289/Ehp.01109S2283 |
0.398 |
|
| 2001 |
Merrill A. Regulation of de novo sphingolipid biosynthesis: A necessary but dangerous pathway Biochemical Society Transactions. 29: A108-A108. DOI: 10.1042/Bst029A108B |
0.307 |
|
| 2001 |
Linn SC, Kim HS, Keane EM, Andras LM, Wang E, Merrill AH. Regulation of de novo sphingolipid biosynthesis and the toxic consequences of its disruption Biochemical Society Transactions. 29: 831-835. DOI: 10.1042/Bst0290831 |
0.392 |
|
| 2000 |
Sullards MC, Lynch DV, Merrill AH, Adams J. Structure determination of soybean and wheat glucosylceramides by tandem mass spectrometry Journal of Mass Spectrometry. 35: 347-353. PMID 10767763 DOI: 10.1002/(Sici)1096-9888(200003)35:3<347::Aid-Jms941>3.0.Co;2-3 |
0.304 |
|
| 2000 |
Schmelz EM, Sullards MC, Dillehay DL, Merrill AH. Colonic cell proliferation and aberrant crypt foci formation are inhibited by dairy glycosphingolipids in 1,2-dimethylhydrazine-treated CF1 mice Journal of Nutrition. 130: 522-527. PMID 10702579 DOI: 10.1093/Jn/130.3.522 |
0.325 |
|
| 1999 |
Riley RT, Norred WP, Wang E, Merrill AH. Alteration in sphingolipid metabolism: Bioassays for fumonisin- and ISP-I-like activity in tissues, cells and other matrices Natural Toxins. 7: 407-414. PMID 11122537 DOI: 10.1002/1522-7189(199911/12)7:6<407::Aid-Nt84>3.0.Co;2-0 |
0.326 |
|
| 1999 |
Merrill AH, Nikolova-Karakashian M, Schmelz EM, Morgan ET, Stewart J. Regulation of cytochrome P450 expression by sphingolipids Chemistry and Physics of Lipids. 102: 131-139. PMID 11001567 DOI: 10.1016/S0009-3084(99)00081-X |
0.359 |
|
| 1999 |
Warden LA, Menaldino DS, Wilson T, Liotta DC, Smith ER, Merrill AH. Identification of ammonium ion and 2,6-bis(ω-aminobutyl)-3,5- diiminopiperazine as endogenous factors that account for the 'burst' of sphingosine upon changing the medium of J774 cells in culture Journal of Biological Chemistry. 274: 33875-33880. PMID 10567348 DOI: 10.1074/Jbc.274.48.33875 |
0.375 |
|
| 1999 |
Wang E, Merrill AH. Ceramide synthase Methods in Enzymology. 311: 15-21. PMID 10563306 DOI: 10.1016/S0076-6879(00)11062-6 |
0.366 |
|
| 1999 |
Augé N, Nikolova-Karakashian M, Carpentier S, Parthasarathy S, Nègre-Salvayre A, Salvayre R, Merrill AH, Levade T. Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase. The Journal of Biological Chemistry. 274: 21533-8. PMID 10419457 DOI: 10.1074/Jbc.274.31.21533 |
0.353 |
|
| 1999 |
Vesper H, Schmelz EM, Nikolova-Karakashian MN, Dillehay DL, Lynch DV, Merrill AH. Sphingolipids in food and the emerging importance of sphingolipids to nutrition. The Journal of Nutrition. 129: 1239-50. PMID 10395583 DOI: 10.1093/Jn/129.7.1239 |
0.343 |
|
| 1998 |
Birt DF, Merrill AH, Barnett T, Enkvetchakul B, Pour PM, Liotta DC, Geisler V, Menaldino DS, Schwartzbauer J. Inhibition of skin carcinomas but not papillomas by sphingosine, N- methylsphingosine, and N-acetylsphingosine Nutrition and Cancer. 31: 119-126. PMID 9770723 DOI: 10.1080/01635589809514690 |
0.301 |
|
| 1998 |
Ciacci-Zanella JR, Merrill AH, Wang E, Jones C. Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cells Food and Chemical Toxicology. 36: 791-804. PMID 9737426 DOI: 10.1016/S0278-6915(98)00034-9 |
0.352 |
|
| 1998 |
Schmelz EM, Dombrink-Kurtzman MA, Roberts PC, Kozutsumi Y, Kawasaki T, Merrill AH. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases Toxicology and Applied Pharmacology. 148: 252-260. PMID 9473533 DOI: 10.1006/Taap.1997.8356 |
0.312 |
|
| 1997 |
Michel C, Van Echten-Deckert G, Rother J, Sandhoff K, Wang E, Merrill AH. Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide Journal of Biological Chemistry. 272: 22432-22437. PMID 9312549 DOI: 10.1074/Jbc.272.36.22432 |
0.365 |
|
| 1997 |
Kok JW, Nikolova-Karakashian M, Klappe K, Alexander C, Merrill AH. Dihydroceramide biology. Structure-specific metabolism and intracellular localization Journal of Biological Chemistry. 272: 21128-21136. PMID 9261117 DOI: 10.1074/Jbc.272.34.21128 |
0.353 |
|
| 1997 |
Nikolova-Karakashian M, Morgan ET, Alexander C, Liotta DC, Merrill AH. Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11) Journal of Biological Chemistry. 272: 18718-18724. PMID 9228043 DOI: 10.1074/Jbc.272.30.18718 |
0.308 |
|
| 1997 |
Schmelz EM, Bushnev AS, Dillehay DL, Liotta DC, Merrill AH. Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. Nutrition and Cancer. 28: 81-5. PMID 9200154 DOI: 10.1080/01635589709514556 |
0.302 |
|
| 1997 |
Smith ER, Jones PL, Boss JM, Merrill AH. Changing J774A.1 cells to new medium perturbs multiple signaling pathways, including the modulation of protein kinase C by endogenous sphingoid bases Journal of Biological Chemistry. 272: 5640-5646. PMID 9038174 DOI: 10.1074/Jbc.272.9.5640 |
0.375 |
|
| 1996 |
Spiegel S, Merrill AH. Sphingolipid metabolism and cell growth regulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 1388-97. PMID 8903509 DOI: 10.1096/Fasebj.10.12.8903509 |
0.352 |
|
| 1996 |
Merrill AH, Wang E, Vales TR, Smith ER, Schroeder JJ, Menaldino DS, Alexander C, Crane HM, Xia J, Liotta DC, Meredith FI, Riley RT. Fumonisin toxicity and sphingolipid biosynthesis. Advances in Experimental Medicine and Biology. 392: 297-306. PMID 8850625 DOI: 10.1007/978-1-4899-1379-1_25 |
0.378 |
|
| 1996 |
Morgan ET, Nikolova-Karakashian M, Chen JQ, Merrill AH. Sphingolipid-dependent signaling in regulation of cytochrome P450 expression Methods in Enzymology. 272: 381-388. PMID 8791797 DOI: 10.1016/S0076-6879(96)72043-8 |
0.329 |
|
| 1996 |
Riley RT, Wang E, Schroeder JJ, Smith ER, Plattner RD, Abbas H, Yoo HS, Merrill AH. Evidence for disruption of sphingolipid metabolism as a contributing factor in the toxicity and carcinogenicity of fumonisins. Natural Toxins. 4: 3-15. PMID 8680751 DOI: 10.1002/19960401Nt2 |
0.376 |
|
| 1996 |
Merrill AH, Liotta DC, Riley RT. Sphingolipids as regulators of cellular growth, differentiation, and behavior Advances in Lipobiology. 1: 273-298. DOI: 10.1016/S1874-5245(96)80012-7 |
0.37 |
|
| 1996 |
Merrill AH. Chapter 12 – Sphingolipids: metabolism and cell signalling New Comprehensive Biochemistry. 31: 309-339. DOI: 10.1016/S0167-7306(08)60519-0 |
0.309 |
|
| 1995 |
Pushkareva M, Chao R, Bielawska A, Merrill AH, Crane HM, Lagu B, Liotta D, Hannun YA. Stereoselectivity of induction of the retinoblastoma gene product (pRb) dephosphorylation by D-erythro-sphingosine supports a role for pRb in growth suppression by sphingosine. Biochemistry. 34: 1885-92. PMID 7849048 DOI: 10.1021/Bi00006A009 |
0.34 |
|
| 1995 |
Merrill AH, Lingrell S, Wang E, Nikolova-Karakashian M, Vales TR, Vance DE. Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein secretion. The Journal of Biological Chemistry. 270: 13834-41. PMID 7775441 DOI: 10.1074/Jbc.270.23.13834 |
0.349 |
|
| 1995 |
Wu WI, McDonough VM, Nickels JT, Ko J, Fischl AS, Vales TR, Merrill AH, Carman GM. Regulation of lipid biosynthesis in Saccharomyces cerevisiae by fumonisin B1 Journal of Biological Chemistry. 270: 13171-13178. PMID 7768913 DOI: 10.1074/Jbc.270.22.13171 |
0.365 |
|
| 1995 |
Smith ER, Merrill AH. Differential roles of de Novo sphingolipid biosynthesis and turnover in the "Burst" of free sphingosine and sphinganine, and their 1-phosphates and N-Acyl-derivatives, that occurs upon changing the medium of cells in culture Journal of Biological Chemistry. 270: 18749-18758. PMID 7642524 DOI: 10.1074/Jbc.270.32.18749 |
0.379 |
|
| 1995 |
Martinova EA, Merrill AH. Fumonisin B1 alters sphingolipid metabolism and immune function in BALB/c mice: Immunological responses to fumonisin B1 Mycopathologia. 130: 163-170. PMID 7566070 DOI: 10.1007/Bf01103100 |
0.303 |
|
| 1995 |
Chen J, Nikolova-Karakashian M, Merrill AH, Morgan ET. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes Journal of Biological Chemistry. 270: 25233-25238. PMID 7559661 DOI: 10.1074/Jbc.270.42.25233 |
0.354 |
|
| 1994 |
Schmelz EM, Crall KJ, Larocque R, Dillehay DL, Merrill AH. Uptake and metabolism of sphingolipids in isolated intestinal loops of mice Journal of Nutrition. 124: 702-712. PMID 8169662 DOI: 10.1093/Jn/124.5.702 |
0.316 |
|
| 1994 |
Riley RT, Wang E, Merrill AH. Liquid Chromatographic Determination of Sphmgamne and Sphingosine: Use of the Free Sphinganine-to-Sphingosine Ratio as a Biomarker for Consumption of Fumonisins Journal of Aoac International. 77: 533-540. DOI: 10.1093/Jaoac/77.2.533 |
0.322 |
|
| 1993 |
Riley RT, An NH, Showker JL, Yoo HS, Norred WP, Chamberlain WJ, Wang E, Merrill AH, Motelin G, Beasley VR. Alteration of tissue and serum sphinganine to sphingosine ratio: an early biomarker of exposure to fumonisin-containing feeds in pigs. Toxicology and Applied Pharmacology. 118: 105-12. PMID 8430417 DOI: 10.1006/Taap.1993.1015 |
0.335 |
|
| 1993 |
Borek C, Merrill AH. Sphingolipids inhibit multistage carcinogenesis and protein kinase C. Basic Life Sciences. 61: 367-71. PMID 8304947 DOI: 10.1007/978-1-4615-2984-2_34 |
0.35 |
|
| 1992 |
Yoo HS, Norred WP, Wang E, Merrill AH, Riley RT. Fumonisin inhibition of de Novo sphingolipid biosynthesis and cytotoxicity are correlated in LLC-PK1 cells Toxicology and Applied Pharmacology. 114: 9-15. PMID 1585377 DOI: 10.1016/0041-008X(92)90090-F |
0.346 |
|
| 1992 |
Merrill AH. Ceramide: A new lipid 'second messenger'? Nutrition Reviews. 50: 78-87. PMID 1565290 DOI: 10.1111/J.1753-4887.1992.Tb01273.X |
0.31 |
|
| 1992 |
Merrill AH, Wang E, LaRocque R, Mullins RE, Morgan ET, Hargrove JL, Bonkovsky HL, Popova IA. Differences in glycogen, lipids, and enzymes in livers from rats flown on COSMOS 2044 Journal of Applied Physiology. 73. PMID 1526942 DOI: 10.1152/Jappl.1992.73.2.S142 |
0.332 |
|
| 1992 |
Norred WP, Wang E, Yoo H, Riley RT, Merrill AH. In vitro toxicology of fumonisins and the mechanistic implications Mycopathologia. 117: 73-78. PMID 1513375 DOI: 10.1007/Bf00497281 |
0.34 |
|
| 1992 |
Merrill AH, Wang E. Enzymes of ceramide biosynthesis Methods in Enzymology. 209: 427-437. PMID 1495423 DOI: 10.1016/0076-6879(92)09053-6 |
0.36 |
|
| 1991 |
Merrill AH. Cell regulation by sphingosine and more complex sphingolipids Journal of Bioenergetics and Biomembranes. 23: 83-104. PMID 2010436 DOI: 10.1007/Bf00768840 |
0.348 |
|
| 1991 |
Borek C, Ong A, Stevens VL, Wang E, Merrill AH. Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate. Proceedings of the National Academy of Sciences of the United States of America. 88: 1953-7. PMID 2000399 DOI: 10.1073/Pnas.88.5.1953 |
0.348 |
|
| 1991 |
Hannun YA, Merrill AH, Bell RM. Use of sphingosine as inhibitor of protein kinase C Methods in Enzymology. 201: 316-328. PMID 1943771 DOI: 10.1016/0076-6879(91)01028-Z |
0.338 |
|
| 1991 |
Merrill AH, Liotta DC. Lipids as hormones and second messengers Current Opinion in Structural Biology. 1: 516-521. DOI: 10.1016/S0959-440X(05)80071-5 |
0.32 |
|
| 1990 |
Stevens VL, Nimkar S, Jamison WC, Liotta DC, Merrill AH. Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C. Biochimica Et Biophysica Acta. 1051: 37-45. PMID 2297538 DOI: 10.1016/0167-4889(90)90171-9 |
0.347 |
|
| 1990 |
Merrill AH, Hoel M, Wang E, Mullins RE, Hargrove JL, Jones DP, Popova IA. Altered carbohydrate, lipid, and xenobiotic metabolism by liver from rats flown on Cosmos 1887. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 4: 95-100. PMID 2295381 DOI: 10.1096/Fasebj.4.1.2295381 |
0.335 |
|
| 1990 |
Merrill AH, Jones DD. An update of the enzymology and regulation of sphingomyelin metabolism. Biochimica Et Biophysica Acta. 1044: 1-12. PMID 2187537 DOI: 10.1016/0005-2760(90)90211-F |
0.361 |
|
| 1990 |
Greenberg P, Merrill AH, Liotta DC, Grabowski GA. Human acid beta-glucosidase: use of sphingosyl and N-alkyl-glucosylamine inhibitors to investigate the properties of the active site. Biochimica Et Biophysica Acta. 1039: 12-20. PMID 2141287 DOI: 10.1016/0167-4838(90)90220-A |
0.302 |
|
| 1989 |
Merrill AH, Nimkar S, Menaldino D, Hannun YA, Loomis C, Bell RM, Tyagi SR, Lambeth JD, Stevens VL, Hunter R, Liotta DC. Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds Biochemistry. 28: 3138-3145. PMID 2742830 DOI: 10.1021/Bi00434A004 |
0.365 |
|
| 1989 |
Merrill AH. Lipid modulators of cell function Nutrition Reviews. 47: 161-169. PMID 2671815 DOI: 10.1111/J.1753-4887.1989.Tb02826.X |
0.361 |
|
| 1989 |
Merrill AH, Stevens VL. Modulation of protein kinase C and diverse cell functions by sphingosine - a pharmacologically interesting compound linking sphingolipids and signal transduction Bba - Molecular Cell Research. 1010: 131-139. PMID 2643437 DOI: 10.1016/0167-4889(89)90152-3 |
0.383 |
|
| 1988 |
Medlock KA, Merrill AH. Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by β-chloroalanine Biochemistry. 27: 7079-7084. PMID 3143407 DOI: 10.1021/Bi00418A061 |
0.338 |
|
| 1988 |
Medlock KA, Merrill AH. Rapid turnover of sphingosine synthesized de novo from [14C]serine by Chinese hamster ovary cells Biochemical and Biophysical Research Communications. 157: 232-237. PMID 3143361 DOI: 10.1016/S0006-291X(88)80037-8 |
0.371 |
|
| 1988 |
Merrill AH, Wang E, Mullins RE. Kinetics of long-chain (sphingoid) base biosynthesis in intact LM cells: Effects of varying the extracellular concentrations of serine and fatty acid precursors of this pathway Biochemistry. 27: 340-345. PMID 3126810 DOI: 10.1021/Bi00401A051 |
0.367 |
|
| 1987 |
Wilson E, Rice WG, Kinkade JM, Merrill AH, Arnold RR, Lambeth JD. Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils. Archives of Biochemistry and Biophysics. 259: 204-14. PMID 2825597 DOI: 10.1016/0003-9861(87)90487-5 |
0.345 |
|
| 1986 |
Merrill AH, Henderson JM, Wang E, Codner MA, Hollins B, Millikan WJ. Activities of the hepatic enzymes of vitamin B6 metabolism for patients with cirrhosis American Journal of Clinical Nutrition. 44: 461-467. PMID 3020959 DOI: 10.1093/Ajcn/44.4.461 |
0.32 |
|
| 1986 |
Merrill AH, Wang E. Highly sensitive methods for assaying the enzymes of vitamin B6 metabolism Methods in Enzymology. 110-116. PMID 3010031 DOI: 10.1016/0076-6879(86)22156-4 |
0.322 |
|
| 1986 |
Merrill AH, Wang E, Yanish M, Nixon DW. Effects of human plasma on lipid metabolism by 3T3-L1 cells Nutrition Research. 6: 923-929. DOI: 10.1016/S0271-5317(86)80067-7 |
0.3 |
|
| 1985 |
Merrill AH, Wang E, Innis WSA, Mullins R. Increases in serum sphingomyelin by 17β-estradiol Lipids. 20: 252-254. PMID 3999932 DOI: 10.1007/Bf02534197 |
0.334 |
|
| 1984 |
Williams RD, Wang E, Merrill AH. Enzymology of long-chain base synthesis by liver: Characterization of serine palmitoyltransferase in rat liver microsomes Archives of Biochemistry and Biophysics. 228: 282-291. PMID 6421234 DOI: 10.1016/0003-9861(84)90069-9 |
0.347 |
|
| 1983 |
Merrill AH. Characterization of serine palmitoyltransferase activity in Chinese hamster ovary cells Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 754: 284-291. PMID 6652105 DOI: 10.1016/0005-2760(83)90144-3 |
0.368 |
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