Year |
Citation |
Score |
2022 |
Banta KL, Xu X, Chitre AS, Au-Yeung A, Takahashi C, O'Gorman WE, Wu TD, Mittman S, Cubas R, Comps-Agrar L, Fulzele A, Bennett EJ, Grogan JL, Hui E, Chiang EY, et al. Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8 T cell responses. Immunity. 55: 512-526.e9. PMID 35263569 DOI: 10.1016/j.immuni.2022.02.005 |
0.243 |
|
2021 |
Xu X, Masubuchi T, Cai Q, Zhao Y, Hui E. Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors. Elife. 10. PMID 34734802 DOI: 10.7554/eLife.74276 |
0.29 |
|
2020 |
Wu W, Zhou Q, Masubuchi T, Shi X, Li H, Xu X, Huang M, Meng L, He X, Zhu H, Gao S, Zhang N, Jing R, Sun J, Wang H, ... Hui E, et al. Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy. Cell. PMID 32730808 DOI: 10.1016/J.Cell.2020.07.018 |
0.389 |
|
2020 |
Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, Bennett EJ, Fu G, Hui E. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2. The Journal of Cell Biology. 219. PMID 32437509 DOI: 10.1083/Jcb.201905085 |
0.36 |
|
2019 |
Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, Hui E. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. PMID 31757674 DOI: 10.1016/J.Immuni.2019.11.003 |
0.34 |
|
2019 |
Sasmal DK, Feng W, Roy S, Leung P, He Y, Cai C, Cao G, Lian H, Qin J, Hui E, Schreiber H, Adams EJ, Huang J. TCR-pMHC bond conformation controls TCR ligand discrimination. Cellular & Molecular Immunology. PMID 31530899 DOI: 10.1038/S41423-019-0273-6 |
0.389 |
|
2019 |
Hui E. Understanding T cell signaling using membrane reconstitution. Immunological Reviews. 291: 44-56. PMID 31402497 DOI: 10.1111/Imr.12767 |
0.476 |
|
2018 |
Zhao Y, Harrison DL, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Reports. 24: 379-390.e6. PMID 29996099 DOI: 10.1016/J.Celrep.2018.06.054 |
0.343 |
|
2017 |
Carbone CB, Kern N, Fernandes RA, Hui E, Su X, Garcia KC, Vale RD. In vitro reconstitution of T cell receptor-mediated segregation of the CD45 phosphatase. Proceedings of the National Academy of Sciences of the United States of America. PMID 29042512 DOI: 10.1073/Pnas.1710358114 |
0.59 |
|
2017 |
Hui E, Cheung J, Zhu J, Su X, Taylor MJ, Wallweber HA, Sasmal DK, Huang J, Kim JM, Mellman I, Vale RD. T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition. Science (New York, N.Y.). PMID 28280247 DOI: 10.1126/Science.Aaf1292 |
0.534 |
|
2016 |
Su X, Ditlev JA, Hui E, Xing W, Banjade S, Okrut J, King DS, Taunton J, Rosen MK, Vale RD. Phase separation of signaling molecules promotes T cell receptor signal transduction. Science (New York, N.Y.). PMID 27056844 DOI: 10.1126/Science.Aad9964 |
0.571 |
|
2016 |
Su X, Ditlev J, Hui E, Banjade S, Okrut J, Taunton J, Rosen M, Vale R. Abstract A087: Phase separation of signaling molecules promotes T cell receptor signal transduction Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A087 |
0.586 |
|
2016 |
Su X, Ditlev J, Hui E, Rosen M, Vale R. Abstract B101: Mechanism of T cell activation by phase separation Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B101 |
0.57 |
|
2015 |
Chang CW, Hui E, Bai J, Bruns D, Chapman ER, Jackson MB. A structural role for the synaptobrevin 2 transmembrane domain in dense-core vesicle fusion pores. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5772-80. PMID 25855187 DOI: 10.1523/Jneurosci.3983-14.2015 |
0.795 |
|
2014 |
Liu H, Bai H, Hui E, Yang L, Evans CS, Wang Z, Kwon SE, Chapman ER. Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment. Elife. 3: e01524. PMID 24569478 DOI: 10.7554/Elife.01524 |
0.799 |
|
2014 |
Hui E, Vale RD. In vitro membrane reconstitution of the T-cell receptor proximal signaling network. Nature Structural & Molecular Biology. 21: 133-42. PMID 24463463 DOI: 10.1038/Nsmb.2762 |
0.578 |
|
2014 |
Liu H, Bai H, Hui E, Yang L, Evans CS, Wang Z, Kwon SE, Chapman ER. Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment Elife. 2014. DOI: 10.7554/eLife.01524.001 |
0.807 |
|
2013 |
Liu H, Bai H, Hui E, Yang L, Evans CS, Wang Z, Kwon SE, Chapman ER. Author response: Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment Elife. DOI: 10.7554/Elife.01524.021 |
0.795 |
|
2011 |
Hui E, Gaffaney JD, Wang Z, Johnson CP, Evans CS, Chapman ER. Mechanism and function of synaptotagmin-mediated membrane apposition. Nature Structural & Molecular Biology. 18: 813-21. PMID 21642967 DOI: 10.1038/Nsmb.2075 |
0.798 |
|
2010 |
Zhang Z, Hui E, Chapman ER, Jackson MB. Regulation of exocytosis and fusion pores by synaptotagmin-effector interactions. Molecular Biology of the Cell. 21: 2821-31. PMID 20573977 DOI: 10.1091/Mbc.E10-04-0285 |
0.723 |
|
2009 |
Zhang Z, Hui E, Chapman ER, Jackson MB. Phosphatidylserine regulation of Ca2+-triggered exocytosis and fusion pores in PC12 cells. Molecular Biology of the Cell. 20: 5086-95. PMID 19828732 DOI: 10.1091/Mbc.E09-08-0691 |
0.755 |
|
2009 |
Hui E, Johnson CP, Yao J, Dunning FM, Chapman ER. Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion. Cell. 138: 709-21. PMID 19703397 DOI: 10.1016/J.Cell.2009.05.049 |
0.799 |
|
2008 |
Gaffaney JD, Dunning FM, Wang Z, Hui E, Chapman ER. Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis. The Journal of Biological Chemistry. 283: 31763-75. PMID 18784080 DOI: 10.1074/Jbc.M803355200 |
0.793 |
|
2008 |
Paddock BE, Striegel AR, Hui E, Chapman ER, Reist NE. Ca2+-dependent, phospholipid-binding residues of synaptotagmin are critical for excitation-secretion coupling in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7458-66. PMID 18650324 DOI: 10.1523/Jneurosci.0197-08.2008 |
0.761 |
|
2008 |
Chicka MC, Hui E, Liu H, Chapman ER. Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+. Nature Structural & Molecular Biology. 15: 827-35. PMID 18622390 DOI: 10.1038/Nsmb.1463 |
0.795 |
|
2008 |
Shahin V, Datta D, Hui E, Henderson RM, Chapman ER, Edwardson JM. Synaptotagmin perturbs the structure of phospholipid bilayers. Biochemistry. 47: 2143-52. PMID 18205405 DOI: 10.1021/Bi701879G |
0.769 |
|
2006 |
Czibener C, Sherer NM, Becker SM, Pypaert M, Hui E, Chapman ER, Mothes W, Andrews NW. Ca2+ and synaptotagmin VII-dependent delivery of lysosomal membrane to nascent phagosomes. The Journal of Cell Biology. 174: 997-1007. PMID 16982801 DOI: 10.1083/Jcb.200605004 |
0.754 |
|
2006 |
Hui E, Bai J, Chapman ER. Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I. Biophysical Journal. 91: 1767-77. PMID 16782782 DOI: 10.1529/Biophysj.105.080325 |
0.843 |
|
2005 |
Hui E, Bai J, Wang P, Sugimori M, Llinas RR, Chapman ER. Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 5210-4. PMID 15793006 DOI: 10.1073/Pnas.0500941102 |
0.85 |
|
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