Frank Jirik - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Neuroscience Biology

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Shin W, Alpaugh W, Hallihan LJ, Sinha S, Crowther E, Martin GR, Scheidl-Yee T, Yang X, Yoon G, Goldsmith T, Berger ND, de Almeida LG, Dufour A, Dobrinski I, Weinfeld M, ... Jirik FR, et al. PNKP is required for maintaining the integrity of progenitor cell populations in adult mice. Life Science Alliance. 4. PMID 34226276 DOI: 10.26508/lsa.202000790  0.368
2019 Martin GR, Blomquist CM, Henare KL, Jirik FR. Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice. Scientific Reports. 9: 14281. PMID 31582793 DOI: 10.1038/S41598-019-50656-5  0.325
2019 Martin GR, Henare K, Salazar C, Scheidl-Yee T, Eggen LJ, Tailor PP, Kim JH, Podstawka J, Fritzler MJ, Kelly MM, Yipp BG, Jirik FR. Expression of a constitutively active human mutant in hematopoietic cells produces an -dependent vasculopathy in mice. Life Science Alliance. 2. PMID 31221625 DOI: 10.26508/lsa.201800215  0.42
2016 Miller KA, Keenan CM, Martin GR, Jirik FR, Sharkey KA, Wieser ME. The expression levels of cellular prion protein affect copper isotopic shifts in the organs of mice Journal of Analytical Atomic Spectrometry. 31: 2015-2022. DOI: 10.1039/C6Ja00195E  0.344
2015 Downey CM, Jirik FR. DNA mismatch repair deficiency accelerates lung neoplasm development in K-ras(LA1/+) mice: a brief report. Cancer Medicine. 4: 897-902. PMID 25773971 DOI: 10.1002/cam4.420  0.393
2011 Martin GR, Keenan CM, Sharkey KA, Jirik FR. Endogenous prion protein attenuates experimentally induced colitis. The American Journal of Pathology. 179: 2290-301. PMID 21924230 DOI: 10.1016/J.Ajpath.2011.07.025  0.348
2009 Downey CM, Horton CR, Carlson BA, Parsons TE, Hatfield DL, Hallgrímsson B, Jirik FR. Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease. Plos Genetics. 5: e1000616. PMID 19696890 DOI: 10.1371/Journal.Pgen.1000616  0.351
2008 Sandercock LE, Hahn JN, Li L, Luchman HA, Giesbrecht JL, Peterson LA, Jirik FR. Mgmt deficiency alters the in vivo mutational spectrum of tissues exposed to the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Carcinogenesis. 29: 866-74. PMID 18281247 DOI: 10.1093/carcin/bgn030  0.501
2007 Ford-Hutchinson AF, Ali Z, Lines SE, Hallgrímsson B, Boyd SK, Jirik FR. Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 1245-59. PMID 17456009 DOI: 10.1359/Jbmr.070420  0.324
2006 Hegan DC, Narayanan L, Jirik FR, Edelmann W, Liskay RM, Glazer PM. Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, Msh2, Msh3 and Msh6. Carcinogenesis. 27: 2402-8. PMID 16728433 DOI: 10.1093/Carcin/Bgl079  0.597
2006 Hallgrímsson B, Brown JJ, Ford-Hutchinson AF, Sheets HD, Zelditch ML, Jirik FR. The brachymorph mouse and the developmental-genetic basis for canalization and morphological integration. Evolution & Development. 8: 61-73. PMID 16409383 DOI: 10.1111/J.1525-142X.2006.05075.X  0.302
2005 Fortier M, Soni K, Laurin N, Wang SP, Mauriège P, Jirik FR, Mitchell GA. Human hormone-sensitive lipase (HSL): expression in white fat corrects the white adipose phenotype of HSL-deficient mice. Journal of Lipid Research. 46: 1860-7. PMID 15961788 DOI: 10.1194/Jlr.M500081-Jlr200  0.369
2005 Ford-Hutchinson AF, Ali Z, Seerattan RA, Cooper DM, Hallgrímsson B, Salo PT, Jirik FR. Degenerative knee joint disease in mice lacking 3'-phosphoadenosine 5'-phosphosulfate synthetase 2 (Papss2) activity: a putative model of human PAPSS2 deficiency-associated arthrosis. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 13: 418-25. PMID 15882565 DOI: 10.1016/J.Joca.2004.12.011  0.383
2004 Cummings KJ, Pendlebury JD, Jirik FR, Sherwood NM, Wilson RJ. A SIDS-like phenotype is associated with reduced respiratory chemoresponses in PACAP deficient neonatal mice. Advances in Experimental Medicine and Biology. 551: 77-83. PMID 15602947 DOI: 10.1007/0-387-27023-X_13  0.307
2004 Sandercock LE, Kwok MC, Luchman HA, Mark SC, Giesbrecht JL, Samson LD, Jirik FR. Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational spectrum. Oncogene. 23: 5931-40. PMID 15208683 DOI: 10.1038/Sj.Onc.1207791  0.543
2004 Moody JL, Jirik FR. Compound heterozygosity for Pten and SHIP augments T-dependent humoral immune responses and cytokine production by CD(4+) T cells. Immunology. 112: 404-12. PMID 15196208 DOI: 10.1111/j.1365-2567.2004.01901.x  0.64
2004 Moody JL, Xu L, Helgason CD, Jirik FR. Anemia, thrombocytopenia, leukocytosis, extramedullary hematopoiesis, and impaired progenitor function in Pten+/-SHIP-/- mice: a novel model of myelodysplasia. Blood. 103: 4503-10. PMID 15001465 DOI: 10.1182/Blood-2003-09-3262  0.697
2003 Moody JL, Pereira CG, Magil A, Fritzler MJ, Jirik FR. Loss of a single allele of SHIP exacerbates the immunopathology of Pten heterozygous mice. Genes and Immunity. 4: 60-6. PMID 12595903 DOI: 10.1038/sj.gene.6363903  0.683
2003 Hadjur S, Jirik FR. Increased sensitivity of Fancc-deficient hematopoietic cells to nitric oxide and evidence that this species mediates growth inhibition by cytokines. Blood. 101: 3877-84. PMID 12521994 DOI: 10.1182/blood-2002-10-3147  0.679
2002 Mark SC, Sandercock LE, Luchman HA, Baross A, Edelmann W, Jirik FR. Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium. Oncogene. 21: 7126-30. PMID 12370835 DOI: 10.1038/Sj.Onc.1205861  0.458
2002 Fox JA, Ung K, Tanlimco SG, Jirik FR. Disruption of a single Pten allele augments the chemotactic response of B lymphocytes to stromal cell-derived factor-1. Journal of Immunology (Baltimore, Md. : 1950). 169: 49-54. PMID 12077227 DOI: 10.4049/Jimmunol.169.1.49  0.546
2001 Hadjur S, Ung K, Wadsworth L, Dimmick J, Rajcan-Separovic E, Scott RW, Buchwald M, Jirik FR. Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase. Blood. 98: 1003-11. PMID 11493445 DOI: 10.1182/Blood.V98.4.1003  0.748
2001 Baross-Francis A, Makhani N, Liskay RM, Jirik FR. Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells. Oncogene. 20: 619-25. PMID 11313994 DOI: 10.1038/Sj.Onc.1204138  0.752
2000 Campbell MR, Thang TY, Jirik FR, Andrew SE. Candidate mutator genes in mismatch repair-deficient thymic lymphomas: No evidence of mutations in the DNA polymerase δ gene Carcinogenesis. 21: 2281-2285. PMID 11133819  0.477
2000 Andrew SE, Xu XS, Baross-Francis A, Narayanan L, Milhausen K, Liskay RM, Jirik FR, Glazer PM. Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions and frameshifts. Carcinogenesis. 21: 1291-5. PMID 10874005 DOI: 10.1093/Carcin/21.7.1291  0.753
2000 Baross-Francis A, Milhausen MK, Andrew SE, Jevon G, Jirik FR. Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene. Carcinogenesis. 21: 1259-62. PMID 10837019 DOI: 10.1093/Carcin/21.6.1259  0.754
2000 Narang M, Waring J, Sabourin L, Rajcan-Separovic E, Parry D, Jirik F, Korneluk R. Skeletal myopathy in mice over-expressing the human myotonic dystrophy protein kinase (DMPK) gene Gene Function & Disease. 1: 134-144. DOI: 10.1002/1438-826X(200010)1:3/4<134::Aid-Gnfd134>3.0.Co;2-W  0.44
1999 Ong CJ, Ip S, Teh SJ, Wong C, Jirik FR, Grusby MJ, Teh HS. A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice Cellular Immunology. 196: 60-68. PMID 10486156 DOI: 10.1006/Cimm.1999.1537  0.39
1999 Andrew SE, Hsiao L, Milhausen K, Jirik FR. Comparison of selectable and plaque assay systems to detect menadione- and UV-induced lacI mutations in mammalian cells Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 427: 89-97. PMID 10393263 DOI: 10.1016/S0027-5107(99)00094-9  0.373
1998 Baross-Francis A, Andrew SE, Penney JE, Jirik FR. Tumors of DNA mismatch repair-deficient hosts exhibit dramatic increases in genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 95: 8739-43. PMID 9671748 DOI: 10.1073/Pnas.95.15.8739  0.741
1998 Andrew SE, McKinnon M, Cheng BS, Francis A, Penney J, Reitmair AH, Mak TW, Jirik FR. Tissues of MSH2-deficient mice demonstrate hypermutability on exposure to a DNA methylating agent. Proceedings of the National Academy of Sciences of the United States of America. 95: 1126-30. PMID 9448296 DOI: 10.1073/pnas.95.3.1126  0.405
1997 Andrew SE, Reitmair AH, Fox J, Hsiao L, Francis A, McKinnon M, Mak TW, Jirik FR. Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice Oncogene. 15: 123-129. PMID 9244348 DOI: 10.1038/Sj.Onc.1201180  0.766
1997 Andrew SE, McKinnon M, Chang B, Francis A, Penney J, Jirik FR. P XV.25 Compared with control mice, MSH2−/− but not MSH2+/− Lacl transgenic mice demonstrate elevated mutation frequencies in response to MNU Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S152. DOI: 10.1016/S0027-5107(97)83148-X  0.454
1996 Andrew SE, Pownall S, Fox J, Hsiao L, Hambleton J, Penney JE, Kohler SW, Jirik FR. A novel lacI transgenic mutation-detection system and its application to establish baseline mutation frequencies in the scid mouse. Mutation Research. 357: 57-66. PMID 8876680 DOI: 10.1016/0027-5107(96)00080-2  0.704
1996 Goldberg YP, Kalchman MA, Metzler M, Nasir J, Zeisler J, Graham R, Koide HB, O'Kusky J, Sharp AH, Ross CA, Jirik F, Hayden MR. Absence of disease phenotype and intergenerational stability of the CAG repeat in transgenic mice expressing the human Huntington disease transcript Human Molecular Genetics. 5: 177-185. PMID 8824873 DOI: 10.1093/Hmg/5.2.177  0.507
1994 Tao W, Teh SJ, Melhado I, Jirik F, Korsmeyer SJ, Teh HS. The T cell receptor repertoire of CD4-8+ thymocytes is altered by overexpression of the BCL-2 protooncogene in the thymus Journal of Experimental Medicine. 179: 145-153. PMID 8270861 DOI: 10.1084/Jem.179.1.145  0.342
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