Year |
Citation |
Score |
2004 |
Chen JQ, Eshete M, Alworth WL, Yager JD. Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors alpha and beta to human mitochondrial DNA estrogen response elements. Journal of Cellular Biochemistry. 93: 358-73. PMID 15368362 DOI: 10.1002/Jcb.20178 |
0.72 |
|
2004 |
Blobaum AL, Kent UM, Alworth WL, Hollenberg PF. Novel reversible inactivation of cytochrome P450 2E1 T303A by tert-butyl acetylene: the role of threonine 303 in proton delivery to the active site of cytochrome P450 2E1. The Journal of Pharmacology and Experimental Therapeutics. 310: 281-90. PMID 14988423 DOI: 10.1124/Jpet.104.065508 |
0.33 |
|
2003 |
Rowley CW, Rajnarayanan RV, Hopkins NE, Alworth WL. Differential expression of CYP102 in Bacillus megaterium by 17-beta-estradiol and 4-sec-butylphenol. Biochemical and Biophysical Research Communications. 300: 102-6. PMID 12480527 DOI: 10.1016/S0006-291X(02)02767-5 |
0.712 |
|
2002 |
Blobaum AL, Kent UM, Alworth WL, Hollenberg PF. Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein. Chemical Research in Toxicology. 15: 1561-71. PMID 12482238 DOI: 10.1021/Tx020052X |
0.318 |
|
2002 |
Schoch GA, Nikov GN, Alworth WL, Werck-Reichhart D. Chemical inactivation of the cinnamate 4-hydroxylase allows for the accumulation of salicylic acid in elicited cells. Plant Physiology. 130: 1022-31. PMID 12376665 DOI: 10.1104/Pp.004309 |
0.71 |
|
2002 |
Kent UM, Mills DE, Rajnarayanan RV, Alworth WL, Hollenberg PF. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites. The Journal of Pharmacology and Experimental Therapeutics. 300: 549-58. PMID 11805216 DOI: 10.1124/Jpet.300.2.549 |
0.317 |
|
2001 |
Rajnarayanan RV, Rowley CW, Hopkins NE, Alworth WL. Regulation of phenobarbital-mediated induction of CYP102 (cytochrome P450(BM-3)) in Bacillus megaterium by phytochemicals from soy and green tea. Journal of Agricultural and Food Chemistry. 49: 4930-6. PMID 11600046 DOI: 10.1021/Jf010563+ |
0.718 |
|
2001 |
Nikov GN, Eshete M, Rajnarayanan RV, Alworth WL. Interactions of synthetic estrogens with human estrogen receptors. The Journal of Endocrinology. 170: 137-45. PMID 11431146 DOI: 10.1677/Joe.0.1700137 |
0.674 |
|
2000 |
Nikov GN, Hopkins NE, Boue S, Alworth WL. Interactions of dietary estrogens with human estrogen receptors and the effect on estrogen receptor-estrogen response element complex formation. Environmental Health Perspectives. 108: 867-72. PMID 11017892 DOI: 10.1289/Ehp.00108867 |
0.742 |
|
1999 |
Ertl RP, Alworth WL, Winston GW. Liver microsomal cytochromes P450-dependent alkoxyphenoxazone O-dealkylation in vitro by alligator and rat: activities, inhibition, substrate preference, and discrimination factors. Journal of Biochemical and Molecular Toxicology. 13: 17-27. PMID 9890444 DOI: 10.1002/(Sici)1099-0461(1999)13:1<17::Aid-Jbt3>3.0.Co;2-6 |
0.318 |
|
1998 |
Roberts ES, Alworth WL, Hollenberg PF. Mechanism-based inactivation of cytochromes P450 2E1 and 2B1 by 5-phenyl-1-pentyne. Archives of Biochemistry and Biophysics. 354: 295-302. PMID 9637739 DOI: 10.1006/Abbi.1998.0679 |
0.339 |
|
1998 |
Hopkins NE, English N, Hughes V, Rowley CW, Wolf CR, Alworth WL. Induction of CYP102 (cytochrome P450BM-3) in Bacillus megaterium by 17 beta-estradiol and 4-sec-butylphenol. Biochemical and Biophysical Research Communications. 244: 868-72. PMID 9535758 DOI: 10.1006/Bbrc.1998.8170 |
0.714 |
|
1996 |
Beebe LE, Roberts ES, Fornwald LW, Hollenberg PF, Alworth WL. Mechanism-based inhibition of mouse P4502b-10 by selected arylalkynes. Biochemical Pharmacology. 52: 1507-13. PMID 8937464 DOI: 10.1016/S0006-2952(96)00525-4 |
0.346 |
|
1996 |
Roberts ES, Pernecky SJ, Alworth WL, Hollenberg PF. A role for threonine 302 in the mechanism-based inactivation of P450 2B4 by 2-ethynylnaphthalene. Archives of Biochemistry and Biophysics. 331: 170-6. PMID 8660695 DOI: 10.1006/Abbi.1996.0295 |
0.328 |
|
1995 |
Roberts ES, Ballou DP, Hopkins NE, Alworth WL, Hollenberg PF. Mechanistic studies of 9-ethynylphenanthrene-inactivated cytochrome P450 2B1. Archives of Biochemistry and Biophysics. 323: 303-12. PMID 7487092 DOI: 10.1006/Abbi.1995.9960 |
0.329 |
|
1993 |
Roberts ES, Hopkins NE, Alworth WL, Hollenberg PF. Mechanism-based inactivation of cytochrome P450 2B1 by 2-ethynylnaphthalene: identification of an active-site peptide. Chemical Research in Toxicology. 6: 470-9. PMID 8374044 DOI: 10.1021/Tx00034A013 |
0.332 |
|
1992 |
Hopkins NE, Foroozesh MK, Alworth WL. Suicide inhibitors of cytochrome P450 1A1 and P450 2B1. Biochemical Pharmacology. 44: 787-96. PMID 1510726 DOI: 10.1016/0006-2952(92)90417-H |
0.324 |
|
1990 |
Viaje A, Lu JY, Hopkins NE, Nettikumara AN, DiGiovanni J, Alworth WL, Slaga TJ. Inhibition of the binding of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene to DNA in mouse skin epidermis by 1-ethynylpyrene. Carcinogenesis. 11: 1139-43. PMID 2115405 DOI: 10.1093/Carcin/11.7.1139 |
0.366 |
|
1989 |
Hammons GJ, Alworth WL, Hopkins NE, Guengerich FP, Kadlubar FF. 2-ethynylnaphthalene as a mechanism-based inactivator of the cytochrome P-450 catalyzed N-oxidation of 2-naphthylamine. Chemical Research in Toxicology. 2: 367-74. PMID 2519725 DOI: 10.1021/Tx00012A003 |
0.321 |
|
1985 |
Gan LS, Lu JY, Hershkowitz DM, Alworth WL. Effects of acetylenic and olefinic pyrenes upon cytochrome P-450 dependent benzo[a]pyrene hydroxylase activity in liver microsomes. Biochemical and Biophysical Research Communications. 129: 591-6. PMID 4015648 DOI: 10.1016/0006-291X(85)90192-5 |
0.31 |
|
1984 |
Gan LS, Acebo AL, Alworth WL. 1-Ethynylpyrene, a suicide inhibitor of cytochrome P-450 dependent benzo[a]pyrene hydroxylase activity in liver microsomes. Biochemistry. 23: 3827-36. PMID 6487578 DOI: 10.1021/Bi00312A006 |
0.32 |
|
1965 |
Alworth WL, Rapoport H. Biosynthesis of the nicotine alkaloids in Nicotiana glutinosa. Interrelationships among nicotine, nornicotine, anabasine, and anatabine. Archives of Biochemistry and Biophysics. 112: 45-53. PMID 5865121 DOI: 10.1016/0003-9861(65)90008-1 |
0.353 |
|
1964 |
Alworth WL, De Selms RC, Rapoport H. The Biosynthesis of Nicotine inNicotiana glutinosafrom Carbon-14 Dioxide Journal of the American Chemical Society. 86: 1608-1616. DOI: 10.1021/Ja01062A034 |
0.304 |
|
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