| Year |
Citation |
Score |
| 2024 |
Northey JJ, Hayward MK, Yui Y, Stashko C, Kai F, Mouw JK, Thakar D, Lakins JN, Ironside AJ, Samson S, Mukhtar RA, Hwang ES, Weaver VM. Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk. Cell Stem Cell. 31: 106-126.e13. PMID 38181747 DOI: 10.1016/j.stem.2023.12.002 |
0.34 |
|
| 2023 |
Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM. Expression of Concern: α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini. Journal of Cell Science. 136. PMID 37855733 DOI: 10.1242/jcs.261623 |
0.77 |
|
| 2023 |
Tharp K, Park S, Timblin G, Richards A, Twells N, Riley N, Peltan E, Shon J, Stevenson E, Tsui K, Palomba F, Lefebvre A, Soens R, Ayad N, Hoeve-Scott JT, ... ... Weaver VM, et al. The microenvironment dictates glycocalyx construction and immune surveillance. Research Square. PMID 37645943 DOI: 10.21203/rs.3.rs-3164966/v1 |
0.713 |
|
| 2023 |
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, ... ... Weaver VM, et al. Design of a mucin-selective protease for targeted degradation of cancer-associated mucins. Nature Biotechnology. PMID 37537499 DOI: 10.1038/s41587-023-01840-6 |
0.468 |
|
| 2023 |
Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM. A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer. Nature Communications. 14: 3561. PMID 37322009 DOI: 10.1038/s41467-023-39085-1 |
0.371 |
|
| 2023 |
Wu B, Liu DA, Guan L, Myint PK, Chin L, Dang H, Xu Y, Ren J, Li T, Yu Z, Jabban S, Mills GB, Nukpezah J, Chen YH, Furth EE, ... ... Weaver VM, et al. Stiff matrix induces exosome secretion to promote tumour growth. Nature Cell Biology. PMID 36797475 DOI: 10.1038/s41556-023-01092-1 |
0.362 |
|
| 2023 |
Northey JJ, Weaver VM. Extracellular Matrix Glycation and Crosslinking in Mammary Tumor Progression. Methods in Molecular Biology (Clifton, N.J.). 2614: 247-260. PMID 36587129 DOI: 10.1007/978-1-0716-2914-7_15 |
0.389 |
|
| 2022 |
Bell ES, Shah P, Zuela-Sopilniak N, Kim D, Varlet AA, Morival JLP, McGregor AL, Isermann P, Davidson PM, Elacqua JJ, Lakins JN, Vahdat L, Weaver VM, Smolka MB, Span PN, et al. Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer. Oncogene. PMID 35896617 DOI: 10.1038/s41388-022-02420-9 |
0.368 |
|
| 2022 |
Northey JJ, Weaver VM. Mechanosensitive steroid hormone signaling and cell fate. Endocrinology. PMID 35678467 DOI: 10.1210/endocr/bqac085 |
0.32 |
|
| 2022 |
Metcalf KJ, Hayward MK, Berens E, Ironside AJ, Stashko C, Hwang ES, Weaver VM. Immunosuppressive glycoproteins associate with breast tumor fibrosis and aggression. Matrix Biology Plus. 14: 100105. PMID 35392183 DOI: 10.1016/j.mbplus.2022.100105 |
0.33 |
|
| 2022 |
Samson S, Northey JJ, Acerbi I, Goga A, Flink CL, Weaver VM, LaBarge MA. NCI's publication affiliation conundrum: Reframing innovation to incentivize an equitable path for advocate representation. Translational Oncology. 16: 101325. PMID 34974281 DOI: 10.1016/j.tranon.2021.101325 |
0.533 |
|
| 2021 |
Rudnick JA, Monkkonen T, Mar FA, Barnes JM, Starobinets H, Goldsmith J, Roy S, Bustamante Eguiguren S, Weaver VM, Debnath J. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes & Development. PMID 34168038 DOI: 10.1101/gad.345629.120 |
0.388 |
|
| 2021 |
Hayward MK, Muncie JM, Weaver VM. Tissue mechanics in stem cell fate, development, and cancer. Developmental Cell. PMID 34107299 DOI: 10.1016/j.devcel.2021.05.011 |
0.422 |
|
| 2021 |
Drain AP, Zahir N, Northey JJ, Zhang H, Huang PJ, Maller O, Lakins JN, Yu X, Leight JL, Alston-Mills BP, Hwang ES, Chen YY, Park CC, Weaver VM. Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer. The Journal of Experimental Medicine. 218. PMID 33822843 DOI: 10.1084/jem.20191360 |
0.802 |
|
| 2021 |
Metcalf KJ, Alazzeh A, Werb Z, Weaver VM. Leveraging microenvironmental synthetic lethalities to treat cancer. The Journal of Clinical Investigation. 131. PMID 33720045 DOI: 10.1172/JCI143765 |
0.535 |
|
| 2020 |
Barkovskaya A, Buffone A, Žídek M, Weaver VM. Proteoglycans as Mediators of Cancer Tissue Mechanics. Frontiers in Cell and Developmental Biology. 8: 569377. PMID 33330449 DOI: 10.3389/fcell.2020.569377 |
0.391 |
|
| 2020 |
Maller O, Drain AP, Barrett AS, Borgquist S, Ruffell B, Zakharevich I, Pham TT, Gruosso T, Kuasne H, Lakins JN, Acerbi I, Barnes JM, Nemkov T, Chauhan A, Gruenberg J, ... ... Weaver VM, et al. Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression. Nature Materials. PMID 33257795 DOI: 10.1038/s41563-020-00849-5 |
0.554 |
|
| 2020 |
Muncie JM, Ayad NME, Lakins JN, Xue X, Fu J, Weaver VM. Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells. Developmental Cell. PMID 33207224 DOI: 10.1016/j.devcel.2020.10.015 |
0.338 |
|
| 2020 |
Weaver VM, Bissell MJ. Zena Werb (1945-2020): Mourning the loss of a tissue microenvironment icon. Proceedings of the National Academy of Sciences of the United States of America. PMID 33122428 DOI: 10.1073/pnas.2020162117 |
0.448 |
|
| 2020 |
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, ... ... Weaver VM, et al. Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Science Translational Medicine. 12. PMID 32817366 DOI: 10.1126/Scitranslmed.Aay8798 |
0.304 |
|
| 2020 |
Jiang H, Torphy RJ, Steiger K, Hongo H, Ritchie AJ, Kriegsmann M, Horst D, Umetsu SE, Joseph NM, McGregor K, Pishvaian MJ, Blais EM, Lu B, Li M, Hollingsworth M, ... ... Weaver VM, et al. Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix. The Journal of Clinical Investigation. PMID 32749238 DOI: 10.1172/Jci136760 |
0.402 |
|
| 2020 |
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, ... ... Weaver VM, et al. Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217. The Journal of Clinical Investigation. PMID 32721948 DOI: 10.1172/Jci129249 |
0.38 |
|
| 2020 |
Piersma B, Hayward MK, Weaver VM. The fibrotic tumor stroma. Biochimica Et Biophysica Acta. Reviews On Cancer. 188356. PMID 32147542 DOI: 10.1016/J.Bbcan.2020.188356 |
0.477 |
|
| 2020 |
Ayad NME, Weaver VM. Tension in tumour cells keeps metabolism high. Nature. 578: 517-518. PMID 32094916 DOI: 10.1038/D41586-020-00314-Y |
0.302 |
|
| 2020 |
Sahai E, Astsaturov I, Cukierman E, DeNardo DG, Egeblad M, Evans RM, Fearon D, Greten FR, Hingorani SR, Hunter T, Hynes RO, Jain RK, Janowitz T, Jorgensen C, Kimmelman AC, ... ... Weaver V, et al. A framework for advancing our understanding of cancer-associated fibroblasts. Nature Reviews. Cancer. PMID 31980749 DOI: 10.1038/S41568-019-0238-1 |
0.553 |
|
| 2020 |
Buffone A, Weaver VM. Don't sugarcoat it: How glycocalyx composition influences cancer progression. The Journal of Cell Biology. 219. PMID 31874115 DOI: 10.1083/Jcb.201910070 |
0.491 |
|
| 2020 |
Tsai K, Weaver VM. Abstract A49: A dual blockade of N-CoR2- and immune checkpoints induces complete remissions in treatment-refractory tumors Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A49 |
0.398 |
|
| 2019 |
Muncie JM, Falcón-Banchs R, Lakins JN, Sohn LL, Weaver VM. Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics. Journal of Visualized Experiments : Jove. PMID 31609314 DOI: 10.3791/60334 |
0.388 |
|
| 2019 |
Zheng Y, Xue X, Shao Y, Wang S, Esfahani SN, Li Z, Muncie JM, Lakins JN, Weaver VM, Gumucio DL, Fu J. Controlled modelling of human epiblast and amnion development using stem cells. Nature. PMID 31511693 DOI: 10.1038/S41586-019-1535-2 |
0.339 |
|
| 2019 |
Eliazer S, Muncie JM, Christensen J, Sun X, D'Urso RS, Weaver VM, Brack AS. Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells. Cell Stem Cell. PMID 31495781 DOI: 10.1016/J.Stem.2019.08.007 |
0.352 |
|
| 2019 |
Ayad NME, Kaushik S, Weaver VM. Tissue mechanics, an important regulator of development and disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 374: 20180215. PMID 31431174 DOI: 10.1098/Rstb.2018.0215 |
0.43 |
|
| 2019 |
Kai F, Drain AP, Weaver VM. The Extracellular Matrix Modulates the Metastatic Journey. Developmental Cell. 49: 332-346. PMID 31063753 DOI: 10.1016/J.Devcel.2019.03.026 |
0.467 |
|
| 2019 |
Huang S, Weaver VM, Tsai KKC. Abstract 5184: N-CoR2 epigenetically regulates adhesion-dependent branching morphogenesis and its loss correlates with malignant progression of the mammary gland Cancer Research. 79: 5184-5184. DOI: 10.1158/1538-7445.Sabcs18-5184 |
0.458 |
|
| 2019 |
Kai F, Ou G, Long A, Guo W, Tourdot R, Radhakrishnan R, Chen C, Dumont S, Weaver VM. Abstract 1028: Extracellular matrix dimensionality reduces cellular cortical tension to stimulate pro-survival signaling in mammary epithelial cells Cancer Research. 79: 1028-1028. DOI: 10.1158/1538-7445.Am2019-1028 |
0.471 |
|
| 2018 |
Libby AR, Joy DA, So PL, Mandegar MA, Muncie JM, Mendoza-Camacho FN, Weaver VM, Conklin BR, McDevitt TC. Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. Elife. 7. PMID 30298816 DOI: 10.7554/Elife.36045 |
0.38 |
|
| 2018 |
Barnes JM, Kaushik S, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lee M, Lee HW, Tung JC, Maller O, Barrett AS, Lu KV, Lakins JN, Hansen KC, ... ... Weaver VM, et al. A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma. Nature Cell Biology. PMID 30202050 DOI: 10.1038/S41556-018-0183-3 |
0.546 |
|
| 2018 |
Tharp KM, Weaver VM. Modeling tissue polarity in context. Journal of Molecular Biology. PMID 30055167 DOI: 10.1016/J.Jmb.2018.07.015 |
0.442 |
|
| 2018 |
Sampayo RG, Toscani AM, Rubashkin MG, Thi K, Masullo LA, Violi IL, Lakins JN, Cáceres A, Hines WC, Coluccio Leskow F, Stefani FD, Chialvo DR, Bissell MJ, Weaver VM, Simian M. Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells. The Journal of Cell Biology. PMID 29980625 DOI: 10.1083/Jcb.201703037 |
0.778 |
|
| 2018 |
Muncie JM, Weaver VM. The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate. Current Topics in Developmental Biology. 130: 1-37. PMID 29853174 DOI: 10.1016/Bs.Ctdb.2018.02.002 |
0.48 |
|
| 2018 |
Samson S, Northey JJ, Plaks V, Baas C, Dean I, LaBarge MA, Goga A, Van't Veer LJ, Weaver VM. New Horizons in Advocacy Engaged Physical Sciences and Oncology Research. Trends in Cancer. 4: 260-264. PMID 29606307 DOI: 10.1016/J.Trecan.2018.02.002 |
0.589 |
|
| 2018 |
Northcott JM, Dean IS, Mouw JK, Weaver VM. Feeling Stress: The Mechanics of Cancer Progression and Aggression. Frontiers in Cell and Developmental Biology. 6: 17. PMID 29541636 DOI: 10.3389/Fcell.2018.00017 |
0.481 |
|
| 2018 |
Takai K, Drain AP, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive basal-like breast cancers. Genes & Development. PMID 29483153 DOI: 10.1101/Gad.301366.117 |
0.625 |
|
| 2018 |
Ilkhanizadeh S, Sabelström H, Miroshnikova YA, Frantz A, Zhu W, Idilli A, Lakins JN, Schmidt C, Quigley D, Fenster T, Yuan E, Trzeciak JR, Saxena S, Lindberg OR, Mouw J, ... ... Weaver VM, et al. Antisecretory Factor-mediated Inhibition of Cell Volume Dynamics Produces Anti-tumor Activity in Glioblastoma. Molecular Cancer Research : McR. PMID 29431617 DOI: 10.1158/1541-7786.Mcr-17-0413 |
0.393 |
|
| 2018 |
Weaver VM. Cell and tissue mechanics: the new cell biology frontier. Molecular Biology of the Cell. 28: 1815-1818. PMID 28684606 DOI: 10.1091/Mbc.E17-05-0320 |
0.412 |
|
| 2018 |
Drain AP, Takai K, Lawson DA, Littlepage LE, Karpuj M, Kessenbrock K, Le A, Inoue K, Weaver VM, Werb Z. Abstract LB-055: Discoidin domain receptor 1 (DDR1) ablation promotes tissue fibrosis and hypoxia to induce aggressive, basal-like breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-055 |
0.635 |
|
| 2018 |
Kaushik S, Barnes JM, Bainer RO, Sa JK, Woods EC, Kai F, Przybyla L, Lakins JN, Phillips JJ, Nam D, Bertozzi CR, Weaver VM. TMIC-43. A TENSION-MEDIATED GLYCOCALYX FEEDBACK LOOP PROMOTES A MESENCHYMAL, STEM-LIKE PHENOTYPE IN GLIOBLASTOMA Neuro-Oncology. 20: vi265-vi266. DOI: 10.1093/Neuonc/Noy148.1102 |
0.454 |
|
| 2018 |
Barrett AS, Maller O, Pickup MW, Weaver VM, Hansen KC. Compartment resolved proteomics reveals a dynamic matrisome in a biomechanically driven model of pancreatic ductal adenocarcinoma Journal of Immunology and Regenerative Medicine. 1: 67-75. DOI: 10.1016/J.Regen.2018.03.002 |
0.384 |
|
| 2017 |
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR. A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression. Elife. 6. PMID 29266001 DOI: 10.7554/Elife.25752 |
0.616 |
|
| 2017 |
Northey JJ, Przybyla L, Weaver VM. Tissue Force Programs Cell Fate and Tumor Aggression. Cancer Discovery. PMID 29038232 DOI: 10.1158/2159-8290.Cd-16-0733 |
0.495 |
|
| 2017 |
Miroshnikova YA, Rozenberg GI, Cassereau L, Pickup M, Mouw JK, Ou G, Templeman KL, Elloumi-Hannachi I, Gooch K, Sarang-Sieminski AL, García AJ, Weaver VM. α5β1-integrinpromotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. Molecular Biology of the Cell. PMID 28877984 DOI: 10.1091/Mbc.E17-02-0126 |
0.506 |
|
| 2017 |
Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. Development of aggressive pancreatic ductal adenocarcinomas depends on granulocyte-colony stimulating factor secretion in carcinoma cells. Cancer Immunology Research. PMID 28775207 DOI: 10.1158/2326-6066.Cir-16-0311 |
0.404 |
|
| 2017 |
Salvador F, Martin A, López-Menéndez C, Moreno-Bueno G, Santos V, Vazquez-Naharro A, Santamaría PG, Morales S, Dubus P, Muinelo-Romay L, López López R, Tung JC, Weaver VM, Portillo F, Cano A. Lysyl oxidase-like protein LOXL2 promotes lung metastasis of breast cancer. Cancer Research. PMID 28720577 DOI: 10.1158/0008-5472.Can-16-3152 |
0.484 |
|
| 2017 |
Oudin MJ, Weaver VM. Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28424337 DOI: 10.1101/Sqb.2016.81.030817 |
0.467 |
|
| 2017 |
Mekhdjian AH, Kai F, Rubashkin MG, Prahl LS, Przybyla LM, McGregor AL, Bell ES, Barnes JM, DuFort CC, Ou G, Chang AC, Cassereau L, Tan SJ, Pickup MW, Lakins JN, ... ... Weaver VM, et al. Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix. Molecular Biology of the Cell. PMID 28381423 DOI: 10.1091/Mbc.E16-09-0654 |
0.504 |
|
| 2017 |
Barnes JM, Przybyla L, Weaver VM. Tissue mechanics regulate brain development, homeostasis and disease. Journal of Cell Science. 130: 71-82. PMID 28043968 DOI: 10.1242/Jcs.191742 |
0.443 |
|
| 2017 |
Woods EC, Kai F, Barnes JM, Pedram K, Pickup MW, Hollander MJ, Weaver VM, Bertozzi CR. Author response: A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression Elife. DOI: 10.7554/Elife.25752.021 |
0.492 |
|
| 2017 |
Dean I, Acerbi I, Mouw J, Shi Q, Chen Y, Liphardt J, Hwang S, Weaver V. Abstract C24: Interplay between ECM stiffness, miR-203 and mammographic density Cancer Epidemiology, Biomarkers & Prevention. 26. DOI: 10.1158/1538-7755.Disp16-C24 |
0.378 |
|
| 2017 |
Barnes JM, Woods EC, Bainer RO, Miroshnikova YA, Lu K, Bergers G, Bertozzi C, Weaver VM. Abstract PR05: Glycoprotein-mediated tissue mechanics regulate glioblastoma aggression Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Pr05 |
0.645 |
|
| 2017 |
Weaver V. Abstract IA09: Extrinsic and intrinsic force regulate cancer progression and aggression Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Ia09 |
0.545 |
|
| 2017 |
Thakar D, Low-Nam ST, Groves JT, Weaver VM. Abstract 5912: Tumor micoenvironment modulates RTK signaling Cancer Research. 77: 5912-5912. DOI: 10.1158/1538-7445.Am2017-5912 |
0.34 |
|
| 2017 |
Tsai KK, Chan T, Hsu C, Pai VC, Huang S, Weaver VM. Abstract 4763: Metronomic chemotherapy prevents therapy-induced stromal activation and induction of cancer stem cells Cancer Research. 77: 4763-4763. DOI: 10.1158/1538-7445.Am2017-4763 |
0.423 |
|
| 2017 |
Kaushik S, Phillips JJ, Weaver VM. Abstract 3985: NCoR2 regulates glioblastoma progression and treatment resistance Cancer Research. 77: 3985-3985. DOI: 10.1158/1538-7445.Am2017-3985 |
0.431 |
|
| 2017 |
Zhang H, Ziaee S, Silva BA, Weaver V, Park C. Stromal Stiffness Increases YAP-Dependent Mediated Cell Survival of Breast Cancer Cells International Journal of Radiation Oncology*Biology*Physics. 99: S149. DOI: 10.1016/j.ijrobp.2017.06.345 |
0.313 |
|
| 2016 |
Chang TT, Thakar D, Weaver VM. Force-dependent breaching of the basement membrane. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 28025167 DOI: 10.1016/J.Matbio.2016.12.005 |
0.435 |
|
| 2016 |
Kaushik S, Pickup MW, Weaver VM. From transformation to metastasis: deconstructing the extracellular matrix in breast cancer. Cancer Metastasis Reviews. PMID 27914000 DOI: 10.1007/S10555-016-9650-0 |
0.486 |
|
| 2016 |
Chan TS, Hsu CC, Pai VC, Liao WY, Huang SS, Tan KT, Yen CJ, Hsu SC, Chen WY, Shan YS, Li CR, Lee MT, Jiang KY, Chu JM, Lien GS, ... Weaver VM, et al. Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells. The Journal of Experimental Medicine. PMID 27881732 DOI: 10.1084/Jem.20151665 |
0.436 |
|
| 2016 |
Miroshnikova YA, Mouw JK, Barnes JM, Pickup MW, Lakins JN, Kim Y, Lobo K, Persson AI, Reis GF, McKnight TR, Holland EC, Phillips JJ, Weaver VM. Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression. Nature Cell Biology. PMID 27820599 DOI: 10.1038/Ncb3429 |
0.393 |
|
| 2016 |
Takai K, Le A, Weaver VM, Werb Z. Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer. Oncotarget. PMID 27756881 DOI: 10.18632/Oncotarget.12658 |
0.591 |
|
| 2016 |
Weaver VM, Gilbert PM. Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease. Seminars in Cell & Developmental Biology. PMID 27641825 DOI: 10.1016/J.Semcdb.2016.09.004 |
0.73 |
|
| 2016 |
Przybyla L, Lakins JN, Weaver VM. Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. Cell Stem Cell. PMID 27452175 DOI: 10.1016/J.Stem.2016.06.018 |
0.425 |
|
| 2016 |
Ou G, Thakar D, Tung JC, Miroshnikova YA, Dufort CC, Gutierrez E, Groisman A, Weaver VM. Visualizing mechanical modulation of nanoscale organization of cell-matrix adhesions. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 27334548 DOI: 10.1039/C6Ib00031B |
0.399 |
|
| 2016 |
Przybyla L, Muncie JM, Weaver VM. Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. Annual Review of Cell and Developmental Biology. PMID 27298087 DOI: 10.1146/Annurev-Cellbio-111315-125150 |
0.463 |
|
| 2016 |
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... ... Weaver VM, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/Nm.4082 |
0.396 |
|
| 2016 |
Kai F, Laklai H, Weaver VM. Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease. Trends in Cell Biology. PMID 27056543 DOI: 10.1016/J.Tcb.2016.03.007 |
0.459 |
|
| 2016 |
Le LT, Cazares O, Mouw JK, Chatterjee S, Macias H, Moran A, Ramos J, Keely PJ, Weaver VM, Hinck L. Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. The Journal of Cell Biology. 212: 707-19. PMID 26975850 DOI: 10.1083/Jcb.201507054 |
0.497 |
|
| 2016 |
Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT. Physiological Ranges of Matrix Rigidity Modulate Primary Mouse Hepatocyte Function In Part Through Hepatocyte Nuclear Factor 4 Alpha. Hepatology (Baltimore, Md.). PMID 26755329 DOI: 10.1002/Hep.28450 |
0.354 |
|
| 2016 |
Przybyla L, Lakins JN, Sunyer R, Trepat X, Weaver VM. Monitoring developmental force distributions in reconstituted embryonic epithelia. Methods (San Diego, Calif.). 94: 101-13. PMID 26342256 DOI: 10.1016/J.Ymeth.2015.09.003 |
0.372 |
|
| 2016 |
Maller O, Cassereau L, Drain A, Ruffell B, Acerbi I, Broz M, Munson J, Swartz M, Krummel M, Coussens L, Weaver V. Abstract A098: A role for fibrosis in promoting pro-tumor immune response in breast cancer Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A098 |
0.456 |
|
| 2016 |
Northey JJ, Yui Y, Mouw JK, Lakins JN, Weaver VM. Abstract PR04: Tissue tension promotes mammary stemness and breast cancer aggression Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-Pr04 |
0.502 |
|
| 2016 |
Barnes JM, Miroshnikova YA, Tung JC, Bainer RO, Weaver VM. Abstract PR10: A glycoprotein-mediated mechanical switch promotes glioma aggression Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-Pr10 |
0.465 |
|
| 2016 |
Liu S, Bainer R, Yui Y, Flinders C, Mallick P, Weaver V, Mumenthaler S. Abstract A23: Characterization of diverging molecular and phenotypic responses under changing extracellular matrix stiffness in MCF10A cells Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-A23 |
0.531 |
|
| 2016 |
Gruosso T, Gigoux M, Bertos N, Saleh S, Omeroglu A, Zuo D, Zhao H, Souleimanova M, Weaver V, Meterissian S, Hallett M, Park M. Abstract A15: Mechanisms of CD8+ T cell immunosuppression in triple negative breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-A15 |
0.4 |
|
| 2016 |
Laklai H, Miroshnikova Y, Pickup M, Collisson E, Grace K, Barrett A, Hill R, Lakins J, Schlaepfer D, Mouw J, LeBleu V, Novitskiy S, Johansen J, Poli V, Kalluri R, ... ... Weaver V, et al. Abstract A50: Genotype tunes PDAC tension to induce matricellular-fibrosis and tumor aggression Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A50 |
0.311 |
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| 2016 |
Northey JJ, Damiano L, Weaver VM. Abstract 911: BRM loss promotes tumor progression through extracellular matrix remodeling and elevated mammary epithelial stem/progenitor activity Cancer Research. 76: 911-911. DOI: 10.1158/1538-7445.Am2016-911 |
0.448 |
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| 2016 |
Dean I, Acerbi I, Au A, Chen Y, Hwang S, Weaver V. Abstract 5100: Interplay between ECM stiffness, miR-203 and mammographic density Cancer Research. 76: 5100-5100. DOI: 10.1158/1538-7445.Am2016-5100 |
0.378 |
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| 2016 |
Weaver V. Tissue Mechanics and Disease Models Biophysical Journal. 110: 1a. DOI: 10.1016/J.Bpj.2015.11.041 |
0.307 |
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| 2015 |
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Weaver VM, et al. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 28: 831-833. PMID 28843279 DOI: 10.1016/J.Ccell.2015.11.002 |
0.314 |
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| 2015 |
Ou G, Weaver VM. Tumor-induced solid stress activates β-catenin signaling to drive malignant behavior in normal, tumor-adjacent cells. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 1293-7. PMID 26439949 DOI: 10.1002/Bies.201500090 |
0.451 |
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| 2015 |
Lin C, Pelissier FA, Zhang H, Lakins J, Weaver VM, Park C, LaBarge MA. Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors. Molecular Biology of the Cell. PMID 26337386 DOI: 10.1091/Mbc.E15-07-0456 |
0.691 |
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| 2015 |
Lau J, Ilkhanizadeh S, Wang S, Miroshnikova YA, Salvatierra NA, Wong RA, Schmidt C, Weaver VM, Weiss WA, Persson AI. STAT3 blockade inhibits radiation-induced malignant progression in glioma. Cancer Research. PMID 26282165 DOI: 10.1158/0008-5472.Can-14-3331 |
0.376 |
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| 2015 |
Acerbi I, Cassereau L, Dean I, Shi Q, Au A, Park C, Chen YY, Liphardt J, Hwang ES, Weaver VM. Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 25959051 DOI: 10.1039/C5Ib00040H |
0.486 |
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| 2015 |
Northcott JM, Northey JJ, Barnes JM, Weaver VM. Fighting the force: Potential of homeobox genes for tumor microenvironment regulation. Biochimica Et Biophysica Acta. 1855: 248-53. PMID 25818365 DOI: 10.1016/J.Bbcan.2015.03.004 |
0.478 |
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| 2015 |
Tung JC, Barnes JM, Desai SR, Sistrunk C, Conklin MW, Schedin P, Eliceiri KW, Keely PJ, Seewaldt VL, Weaver VM. Tumor mechanics and metabolic dysfunction. Free Radical Biology & Medicine. 79: 269-80. PMID 25532934 DOI: 10.1016/J.Freeradbiomed.2014.11.020 |
0.434 |
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| 2015 |
Cassereau L, Miroshnikova YA, Ou G, Lakins J, Weaver VM. A 3D tension bioreactor platform to study the interplay between ECM stiffness and tumor phenotype. Journal of Biotechnology. 193: 66-9. PMID 25435379 DOI: 10.1016/J.Jbiotec.2014.11.008 |
0.448 |
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| 2015 |
Bainer R, Yui Y, Mumenthaler S, Mallick P, Liu L, Wu H, Podlaha O, Michor F, Liphardt J, Licht J, Weaver V. Abstract PR09: Extracellular stiffness cues drive spatial reorganization of the genome to globally constrain RNA abundance Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr09 |
0.439 |
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| 2015 |
Iikhanizadeh S, Miroshnikova Y, Frantz A, Zhu W, Idilli A, Quigley D, Lakins J, Magnitsky S, Phillips J, James D, Berger M, Arosio D, Sun D, Weaver V, Weiss W, et al. ATPS-63OSMOTIC SWELLING REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA Neuro-Oncology. 17: v32.1-v32. DOI: 10.1093/Neuonc/Nov204.63 |
0.416 |
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| 2015 |
Tsai K, Weaver V. Metronomic chemotherapy prevents pancreatic cancers from enhanced stemness induced by stroma-derived ELR+ CXC-chemokine signaling Pancreatology. 15: S31. DOI: 10.1016/J.Pan.2015.05.139 |
0.304 |
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| 2014 |
Pickup MW, Mouw JK, Weaver VM. The extracellular matrix modulates the hallmarks of cancer. Embo Reports. 15: 1243-53. PMID 25381661 DOI: 10.15252/Embr.201439246 |
0.507 |
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| 2014 |
Mouw JK, Ou G, Weaver VM. Extracellular matrix assembly: a multiscale deconstruction. Nature Reviews. Molecular Cell Biology. 15: 771-85. PMID 25370693 DOI: 10.1038/Nrm3902 |
0.413 |
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| 2014 |
Weaver VM. The microenvironment matters. Molecular Biology of the Cell. 25: 3254-8. PMID 25360044 DOI: 10.1091/Mbc.E14-06-1080 |
0.312 |
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| 2014 |
Rubashkin MG, Cassereau L, Bainer R, DuFort CC, Yui Y, Ou G, Paszek MJ, Davidson MW, Chen YY, Weaver VM. Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Research. 74: 4597-611. PMID 25183785 DOI: 10.1158/0008-5472.Can-13-3698 |
0.76 |
|
| 2014 |
Venugopalan G, Camarillo DB, Webster KD, Reber CD, Sethian JA, Weaver VM, Fletcher DA, El-Samad H, Rycroft CH. Multicellular architecture of malignant breast epithelia influences mechanics. Plos One. 9: e101955. PMID 25111489 DOI: 10.1371/Journal.Pone.0101955 |
0.47 |
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| 2014 |
Paszek MJ, DuFort CC, Rossier O, Bainer R, Mouw JK, Godula K, Hudak JE, Lakins JN, Wijekoon AC, Cassereau L, Rubashkin MG, Magbanua MJ, Thorn KS, Davidson MW, Rugo HS, ... ... Weaver VM, et al. The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 511: 319-25. PMID 25030168 DOI: 10.1038/Nature13535 |
0.79 |
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| 2014 |
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Weaver VM, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/J.Ccr.2014.04.005 |
0.407 |
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| 2014 |
Michor F, Weaver VM. Understanding tissue context influences on intratumour heterogeneity. Nature Cell Biology. 16: 301-2. PMID 24691256 DOI: 10.1038/Ncb2942 |
0.444 |
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| 2014 |
Rubashkin MG, Ou G, Weaver VM. Deconstructing signaling in three dimensions. Biochemistry. 53: 2078-90. PMID 24649923 DOI: 10.1021/Bi401710D |
0.387 |
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| 2014 |
Mouw JK, Yui Y, Damiano L, Bainer RO, Lakins JN, Acerbi I, Ou G, Wijekoon AC, Levental KR, Gilbert PM, Hwang ES, Chen YY, Weaver VM. Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nature Medicine. 20: 360-7. PMID 24633304 DOI: 10.1038/Nm.3497 |
0.796 |
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| 2014 |
Shi Q, Ghosh RP, Engelke H, Rycroft CH, Cassereau L, Sethian JA, Weaver VM, Liphardt JT. Rapid disorganization of mechanically interacting systems of mammary acini. Proceedings of the National Academy of Sciences of the United States of America. 111: 658-63. PMID 24379367 DOI: 10.1073/Pnas.1311312110 |
0.34 |
|
| 2014 |
Damiano L, Stewart KM, Cohet N, Mouw JK, Lakins JN, Debnath J, Reisman D, Nickerson JA, Imbalzano AN, Weaver VM. Oncogenic targeting of BRM drives malignancy through C/EBPβ-dependent induction of α5 integrin. Oncogene. 33: 2441-53. PMID 23770848 DOI: 10.1038/Onc.2013.220 |
0.427 |
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| 2014 |
Laklai H, Miroshnikova Y, lakins J, Sergey N, Gorska A, Korets L, Kalluri R, Moses H, Weaver V. Abstract LB-143: Interplay between tissue tension and inflammation in pancreatic tumor progression Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-143 |
0.479 |
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| 2014 |
Bainer R, Yui Y, Mumenthaler S, Mallick P, Podlaha O, Michor F, Liphardt J, Licht J, Weaver V. Abstract 2344: 3D extracellular stiffness cues drive localized changes in gene expression Cancer Research. 74: 2344-2344. DOI: 10.1158/1538-7445.Am2014-2344 |
0.435 |
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| 2014 |
Ilkhanizadeh S, Miroshnikova Y, Frantz A, James D, Berger M, McKnight T, Weaver V, Weiss W, Persson A. NT-11 * TARGETING INTERSTITIAL FLUID PRESSURE TO REDUCE TUMOR GROWTH AND INCREASE DRUG UPTAKE IN BRAIN TUMORS Neuro-Oncology. 16: v161-v161. DOI: 10.1093/Neuonc/Nou265.11 |
0.419 |
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| 2014 |
Persson AI, Ilkhanizadeh S, Miroshnikova YA, Frantz A, Lakins JN, James CD, McKnight TR, Berger MS, Bergers G, Weiss WA, Weaver VM. HIGH INTERSTITIAL FLUID PRESSURE REGULATES TUMOR GROWTH AND DRUG UPTAKE IN HUMAN GLIOBLASTOMA Neuro-Oncology. 16: iii32-iii32. DOI: 10.1093/Neuonc/Nou208.37 |
0.421 |
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| 2014 |
Park C, Zhang H, Weaver V. Tensional Properties of Extracellular Matrix (ECM) Modulate Radiation Resistance via Yes Associated Protein (YAP) International Journal of Radiation Oncology*Biology*Physics. 90: S772. DOI: 10.1016/J.Ijrobp.2014.05.2234 |
0.311 |
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| 2014 |
Rubashkin MG, Dufort C, Oakes P, Paszek M, Ou G, Lakins J, Davidson M, Gardel M, Weaver V. The Nanoscale Organization of Focal Adhesion Signaling Complexes can Reflect Changes in Cellular Contractility and Motility Biophysical Journal. 106: 575a-576a. DOI: 10.1016/J.Bpj.2013.11.3190 |
0.709 |
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| 2013 |
Bainer R, Weaver V. Strength under tension Science. 341: 965-966. PMID 23990548 DOI: 10.1126/Science.1243643 |
0.323 |
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| 2013 |
Pickup MW, Laklai H, Acerbi I, Owens P, Gorska AE, Chytil A, Aakre M, Weaver VM, Moses HL. Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. Cancer Research. 73: 5336-46. PMID 23856251 DOI: 10.1158/0008-5472.Can-13-0012 |
0.48 |
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| 2013 |
Maller O, Hansen KC, Lyons TR, Acerbi I, Weaver VM, Prekeris R, Tan AC, Schedin P. Collagen architecture in pregnancy-induced protection from breast cancer. Journal of Cell Science. 126: 4108-10. PMID 23843613 DOI: 10.1242/Jcs.121590 |
0.52 |
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| 2013 |
Maller O, DuFort CC, Weaver VM. YAP forces fibroblasts to feel the tension. Nature Cell Biology. 15: 570-2. PMID 23728464 DOI: 10.1038/Ncb2777 |
0.441 |
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| 2013 |
Tang Y, Rowe RG, Botvinick EL, Kurup A, Putnam AJ, Seiki M, Weaver VM, Keller ET, Goldstein S, Dai J, Begun D, Saunders T, Weiss SJ. MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis. Developmental Cell. 25: 402-16. PMID 23685250 DOI: 10.1016/J.Devcel.2013.04.011 |
0.377 |
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| 2013 |
Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, ... ... Weaver VM, et al. A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. 3: 1449. PMID 23618955 DOI: 10.1038/Srep01449 |
0.701 |
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| 2013 |
Li CR, Su JJ, Wang WY, Lee MT, Wang TY, Jiang KY, Li CF, Hsu JM, Chen CK, Chen M, Jiang SS, Weaver VM, Tsai KK. Molecular profiling of prostatic acinar morphogenesis identifies PDCD4 and KLF6 as tissue architecture-specific prognostic markers in prostate cancer. The American Journal of Pathology. 182: 363-74. PMID 23219426 DOI: 10.1016/J.Ajpath.2012.10.024 |
0.333 |
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| 2013 |
Maller O, Hansen KC, Weaver V, Prekeris R, Schedin P. Abstract B090: Collagen organization implicated in tumor dormancy Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B090 |
0.515 |
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| 2013 |
Pickup MW, Owens P, Gorska A, Chytil A, Weaver V, Moses H. Abstract A16: Stromal LOX promotes TGFβR2 null breast cancer metastasis Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-A16 |
0.507 |
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| 2013 |
Barnes JM, Weaver VM. Abstract B04: The role of mechanical force and integrin-ECM signaling in glioblastoma aggression Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-B04 |
0.534 |
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| 2013 |
Acerbi I, Hwang S, Munson J, Au A, Zheng S, Yu H, Mouw J, Lakins J, Swartz M, Shi Q, Liphardt J, Ruffell B, Coussen L, Yunn-Yi C, Weaver V. Abstract S2-06: Extracellular matrix stiffness modulates tissue inflammation to promote breast tumor aggression Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-S2-06 |
0.455 |
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| 2012 |
Lakins JN, Chin AR, Weaver VM. Exploring the link between human embryonic stem cell organization and fate using tension-calibrated extracellular matrix functionalized polyacrylamide gels. Methods in Molecular Biology (Clifton, N.J.). 916: 317-50. PMID 22914951 DOI: 10.1007/978-1-61779-980-8_24 |
0.407 |
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| 2012 |
Paszek MJ, DuFort CC, Rubashkin MG, Davidson MW, Thorn KS, Liphardt JT, Weaver VM. Scanning angle interference microscopy reveals cell dynamics at the nanoscale. Nature Methods. 9: 825-7. PMID 22751201 DOI: 10.1038/Nmeth.2077 |
0.676 |
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| 2012 |
Cassereau L, DuFort CC, Weaver VM. Morphogenesis: Laying down the tracks. Nature Materials. 11: 490-2. PMID 22614514 DOI: 10.1038/Nmat3345 |
0.407 |
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| 2012 |
Lu P, Weaver VM, Werb Z. The extracellular matrix: a dynamic niche in cancer progression. The Journal of Cell Biology. 196: 395-406. PMID 22351925 DOI: 10.1083/Jcb.201102147 |
0.605 |
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| 2012 |
Laklai H, Kalluri R, Moses H, Weaver V, Ijichi H, Lakins J, Miroshnikova Y, Acerbi I, Lopez J, Kassianidou E, Gorska A, Novitskiy S. Abstract A47: Reciprocal dialogue between cellular and extracellular matrix tension and tissue inflammation in pancreatic tumor progression. Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A47 |
0.488 |
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| 2012 |
Weaver VM. Abstract SY28-03: The dynamic interplay between extrinsic and intrinsic force regulates cancer progression Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy28-03 |
0.54 |
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| 2012 |
Yui Y, Mouw J, Yu H, Paszek MM, Lakins J, Weaver V. Abstract LB-494: Forcing integrin signaling perturbs mammary morphogenesis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-494 |
0.475 |
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| 2012 |
Pickup M, Chytil A, Gorska A, Aakre M, Weaver V, Moses H. Abstract 2456: TGF-Beta regulates tumor ECM remodeling and progression to metastasis Cancer Research. 72: 2456-2456. DOI: 10.1158/1538-7445.Am2012-2456 |
0.471 |
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| 2012 |
Yu H, Yui Y, Weaver V. Abstract 1477: Tumor metastasis is modulated by tissue stiffness in MMTV-PyMT breast cancer model Cancer Research. 72: 1477-1477. DOI: 10.1158/1538-7445.Am2012-1477 |
0.509 |
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| 2012 |
Acerbi I, Zheng S, Ruffell B, Au A, Shi Q, Liphardt J, Coussens L, Chen Y, Hwang E, Weaver V. 377 Extra-cellular Matrix Stiffness and Immune Cells Infiltrate Are Associated With Breast Tumor Phenotype European Journal of Cancer. 48: S91. DOI: 10.1016/S0959-8049(12)71063-8 |
0.447 |
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| 2012 |
Miroshnikova Y, Acerbi I, Ilkhanizadeh S, Paszek M, Persson A, Weaver V. 159 The Role of the Biophysical Properties of the Glycocalyx and Extracellular Matrix Tension in Enhancing Glioma Cell Invasion European Journal of Cancer. 48: S38-S39. DOI: 10.1016/S0959-8049(12)70859-6 |
0.715 |
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| 2012 |
Zheng S, Acerbi I, Kuhn N, Au A, Park C, Weaver V. Ionizing Radiation Modifies Tissue Tension, Mechanosignaling, and Apoptosis in Human Breast International Journal of Radiation Oncology*Biology*Physics. 84: S669. DOI: 10.1016/J.Ijrobp.2012.07.1786 |
0.327 |
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| 2011 |
Lu P, Takai K, Weaver VM, Werb Z. Extracellular matrix degradation and remodeling in development and disease. Cold Spring Harbor Perspectives in Biology. 3. PMID 21917992 DOI: 10.1101/Cshperspect.A005058 |
0.607 |
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| 2011 |
Lopez JI, Kang I, You WK, McDonald DM, Weaver VM. In situ force mapping of mammary gland transformation. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 910-21. PMID 21842067 DOI: 10.1039/C1Ib00043H |
0.512 |
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| 2011 |
Samuel MS, Lopez JI, McGhee EJ, Croft DR, Strachan D, Timpson P, Munro J, Schröder E, Zhou J, Brunton VG, Barker N, Clevers H, Sansom OJ, Anderson KI, Weaver VM, et al. Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth. Cancer Cell. 19: 776-91. PMID 21665151 DOI: 10.1016/J.Ccr.2011.05.008 |
0.459 |
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| 2011 |
DuFort CC, Paszek MJ, Weaver VM. Balancing forces: architectural control of mechanotransduction. Nature Reviews. Molecular Cell Biology. 12: 308-19. PMID 21508987 DOI: 10.1038/Nrm3112 |
0.71 |
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| 2011 |
Dvorak HF, Weaver VM, Tlsty TD, Bergers G. Tumor microenvironment and progression. Journal of Surgical Oncology. 103: 468-74. PMID 21480238 DOI: 10.1002/Jso.21709 |
0.421 |
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| 2011 |
Miroshnikova YA, Jorgens DM, Spirio L, Auer M, Sarang-Sieminski AL, Weaver VM. Engineering strategies to recapitulate epithelial morphogenesis within synthetic three-dimensional extracellular matrix with tunable mechanical properties. Physical Biology. 8: 026013. PMID 21441648 DOI: 10.1088/1478-3975/8/2/026013 |
0.45 |
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| 2011 |
Yu H, Mouw JK, Weaver VM. Forcing form and function: biomechanical regulation of tumor evolution. Trends in Cell Biology. 21: 47-56. PMID 20870407 DOI: 10.1016/J.Tcb.2010.08.015 |
0.504 |
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| 2011 |
Miroshnikova YA, Acerbi I, Persson A, Paszek MJ, Weiss WA, Weaver VM. Abstract LB-96: Extrinsic and intrinsic force and GBM aggression Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-96 |
0.742 |
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| 2011 |
Acerbi I, Alfred A, Lopez J, Hwang S, Weaver V. Abstract 416: Mammographic density and ECM stiffness Cancer Research. 71: 416-416. DOI: 10.1158/1538-7445.Am2011-416 |
0.416 |
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| 2010 |
Frantz C, Stewart KM, Weaver VM. The extracellular matrix at a glance. Journal of Cell Science. 123: 4195-200. PMID 21123617 DOI: 10.1242/Jcs.023820 |
0.399 |
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| 2010 |
Egeblad M, Rasch MG, Weaver VM. Dynamic interplay between the collagen scaffold and tumor evolution. Current Opinion in Cell Biology. 22: 697-706. PMID 20822891 DOI: 10.1016/J.Ceb.2010.08.015 |
0.49 |
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| 2010 |
Brown XQ, Bartolak-Suki E, Williams C, Walker ML, Weaver VM, Wong JY. Effect of substrate stiffness and PDGF on the behavior of vascular smooth muscle cells: implications for atherosclerosis. Journal of Cellular Physiology. 225: 115-22. PMID 20648629 DOI: 10.1002/Jcp.22202 |
0.344 |
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| 2010 |
Gilbert PM, Mouw JK, Unger MA, Lakins JN, Gbegnon MK, Clemmer VB, Benezra M, Licht JD, Boudreau NJ, Tsai KK, Welm AL, Feldman MD, Weber BL, Weaver VM. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. The Journal of Clinical Investigation. 120: 1535-50. PMID 20389018 DOI: 10.1172/Jci39534 |
0.74 |
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| 2010 |
Cohet N, Stewart KM, Mudhasani R, Asirvatham AJ, Mallappa C, Imbalzano KM, Weaver VM, Imbalzano AN, Nickerson JA. SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells. Journal of Cellular Physiology. 223: 667-78. PMID 20333683 DOI: 10.1002/Jcp.22072 |
0.463 |
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| 2010 |
Paszek M, Weaver V. Enforcing order on signaling Science. 327: 1335-1336. PMID 20223974 DOI: 10.1126/Science.1187865 |
0.683 |
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| 2010 |
Su JJ-, Li C, Lee MT-, Chu PYW, Weaver VM, Tsai KK-. A gene expression signature associated with structural differentiation of prostate acini predicts postoperative recurrence of prostate cancer Clinical Cancer Research. 16. DOI: 10.1158/Diag-10-A22 |
0.304 |
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| 2010 |
Yu H, Weaver VM. Abstract LB-198: Collagen remodeling and tissue mechanics at different stages of mammary tumor development Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-198 |
0.38 |
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| 2009 |
Paszek MJ, Boettiger D, Weaver VM, Hammer DA. Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. Plos Computational Biology. 5: e1000604. PMID 20011123 DOI: 10.1371/Journal.Pcbi.1000604 |
0.732 |
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| 2009 |
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell. 139: 891-906. PMID 19931152 DOI: 10.1016/J.Cell.2009.10.027 |
0.744 |
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| 2009 |
Hansma P, Yu H, Schultz D, Rodriguez A, Yurtsev EA, Orr J, Tang S, Miller J, Wallace J, Zok F, Li C, Souza R, Proctor A, Brimer D, Nogues-Solan X, ... ... Weaver V, et al. The tissue diagnostic instrument. The Review of Scientific Instruments. 80: 054303. PMID 19485522 DOI: 10.1063/1.3127602 |
0.358 |
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| 2009 |
Gehler S, Baldassarre M, Lad Y, Leight JL, Wozniak MA, Riching KM, Eliceiri KW, Weaver VM, Calderwood DA, Keely PJ. Filamin A-beta1 integrin complex tunes epithelial cell response to matrix tension. Molecular Biology of the Cell. 20: 3224-38. PMID 19458194 DOI: 10.1091/Mbc.E08-12-1186 |
0.419 |
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| 2009 |
Engler AJ, Humbert PO, Wehrle-Haller B, Weaver VM. Multiscale modeling of form and function. Science (New York, N.Y.). 324: 208-12. PMID 19359578 DOI: 10.1126/Science.1170107 |
0.422 |
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| 2009 |
Vasilatos SN, Broadwater G, Barry WT, Baker JC, Lem S, Dietze EC, Bean GR, Bryson AD, Pilie PG, Goldenberg V, Skaar D, Paisie C, Torres-Hernandez A, Grant TL, Wilke LG, ... ... Weaver VM, et al. CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 901-14. PMID 19258476 DOI: 10.1158/1055-9965.Epi-08-0875 |
0.365 |
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| 2009 |
Butcher DT, Alliston T, Weaver VM. A tense situation: forcing tumour progression. Nature Reviews. Cancer. 9: 108-22. PMID 19165226 DOI: 10.1038/Nrc2544 |
0.378 |
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| 2009 |
Kumar S, Weaver VM. Mechanics, malignancy, and metastasis: the force journey of a tumor cell. Cancer Metastasis Reviews. 28: 113-27. PMID 19153673 DOI: 10.1007/S10555-008-9173-4 |
0.505 |
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| 2009 |
Erler JT, Weaver VM. Three-dimensional context regulation of metastasis. Clinical & Experimental Metastasis. 26: 35-49. PMID 18814043 DOI: 10.1007/S10585-008-9209-8 |
0.482 |
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| 2008 |
Lopez JI, Mouw JK, Weaver VM. Biomechanical regulation of cell orientation and fate Oncogene. 27: 6981-6993. PMID 19029939 DOI: 10.1038/Onc.2008.348 |
0.5 |
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| 2008 |
Rizki A, Weaver VM, Lee SY, Rozenberg GI, Chin K, Myers CA, Bascom JL, Mott JD, Semeiks JR, Grate LR, Mian IS, Borowsky AD, Jensen RA, Idowu MO, Chen F, et al. A human breast cell model of preinvasive to invasive transition. Cancer Research. 68: 1378-87. PMID 18316601 DOI: 10.1158/0008-5472.Can-07-2225 |
0.808 |
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| 2008 |
Yee KL, Weaver VM, Hammer DA. Integrin-mediated signalling through the MAP-kinase pathway. Iet Systems Biology. 2: 8-15. PMID 18248081 DOI: 10.1049/Iet-Syb:20060058 |
0.528 |
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| 2008 |
Fournier AK, Campbell LE, Castagnino P, Liu WF, Chung BM, Weaver VM, Chen CS, Assoian RK. Rac-dependent cyclin D1 gene expression regulated by cadherin- and integrin-mediated adhesion. Journal of Cell Science. 121: 226-33. PMID 18187454 DOI: 10.1242/Jcs.017012 |
0.385 |
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| 2008 |
Hebner C, Weaver VM, Debnath J. Modeling morphogenesis and oncogenesis in three-dimensional breast epithelial cultures. Annual Review of Pathology. 3: 313-39. PMID 18039125 DOI: 10.1146/Annurev.Pathmechdis.3.121806.151526 |
0.402 |
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| 2007 |
Weaver V, Werb Z. G'rab'bing the microenvironment for invasion. Developmental Cell. 13: 462-3. PMID 17925222 DOI: 10.1016/J.Devcel.2007.09.013 |
0.601 |
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| 2007 |
Friedland JC, Lakins JN, Kazanietz MG, Chernoff J, Boettiger D, Weaver VM. alpha6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-kappaB-dependent resistance to apoptosis in 3D mammary acini. Journal of Cell Science. 120: 3700-12. PMID 17911169 DOI: 10.1242/Jcs.03484 |
0.806 |
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| 2007 |
Kass L, Erler JT, Dembo M, Weaver VM. Mammary epithelial cell: influence of extracellular matrix composition and organization during development and tumorigenesis. The International Journal of Biochemistry & Cell Biology. 39: 1987-94. PMID 17719831 DOI: 10.1016/J.Biocel.2007.06.025 |
0.513 |
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| 2007 |
Johnson KR, Leight JL, Weaver VM. Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis. Methods in Cell Biology. 83: 547-83. PMID 17613324 DOI: 10.1016/S0091-679X(07)83023-8 |
0.429 |
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| 2006 |
Boudreau N, Weaver V. Forcing the Third Dimension Cell. 125: 429-431. PMID 16678088 DOI: 10.1016/J.Cell.2006.04.019 |
0.387 |
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| 2006 |
Underwood JM, Imbalzano KM, Weaver VM, Fischer AH, Imbalzano AN, Nickerson JA. The ultrastructure of MCF-10A acini. Journal of Cellular Physiology. 208: 141-8. PMID 16607610 DOI: 10.1002/Jcp.20639 |
0.382 |
|
| 2005 |
Yan Y, Weaver VM, Blair IA. Analysis of protein expression during oxidative stress in breast epithelial cells using a stable isotope labeled proteome internal standard. Journal of Proteome Research. 4: 2007-14. PMID 16335945 DOI: 10.1021/Pr050175D |
0.389 |
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| 2005 |
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM. Tensional homeostasis and the malignant phenotype. Cancer Cell. 8: 241-54. PMID 16169468 DOI: 10.1016/J.Ccr.2005.08.010 |
0.813 |
|
| 2005 |
Yang C, Liu Y, Leskow FC, Weaver VM, Kazanietz MG. Rac-GAP-dependent inhibition of breast cancer cell proliferation by {beta}2-chimerin. The Journal of Biological Chemistry. 280: 24363-70. PMID 15863513 DOI: 10.1074/Jbc.M411629200 |
0.405 |
|
| 2005 |
Cowden Dahl KD, Robertson SE, Weaver VM, Simon MC. Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression. Molecular Biology of the Cell. 16: 1901-12. PMID 15689487 DOI: 10.1091/Mbc.E04-12-1082 |
0.448 |
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| 2005 |
Yeung T, Georges PC, Flanagan LA, Marg B, Ortiz M, Funaki M, Zahir N, Ming W, Weaver V, Janmey PA. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motility and the Cytoskeleton. 60: 24-34. PMID 15573414 DOI: 10.1002/Cm.20041 |
0.795 |
|
| 2004 |
Paszek MJ, Weaver VM. The tension mounts: mechanics meets morphogenesis and malignancy. Journal of Mammary Gland Biology and Neoplasia. 9: 325-42. PMID 15838603 DOI: 10.1007/S10911-004-1404-X |
0.746 |
|
| 2004 |
Zahir N, Weaver VM. Death in the third dimension: apoptosis regulation and tissue architecture. Current Opinion in Genetics & Development. 14: 71-80. PMID 15108808 DOI: 10.1016/J.Gde.2003.12.005 |
0.815 |
|
| 2004 |
Weaver VM, Gilbert P. Watch thy neighbor: cancer is a communal affair. Journal of Cell Science. 117: 1287-90. PMID 15020668 DOI: 10.1242/Jcs.01137 |
0.753 |
|
| 2003 |
Zahir N, Lakins JN, Russell A, Ming W, Chatterjee C, Rozenberg GI, Marinkovich MP, Weaver VM. Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors. The Journal of Cell Biology. 163: 1397-407. PMID 14691145 DOI: 10.1083/Jcb.200302023 |
0.806 |
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| 2003 |
Russell AJ, Fincher EF, Millman L, Smith R, Vela V, Waterman EA, Dey CN, Guide S, Weaver VM, Marinkovich MP. Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin. Journal of Cell Science. 116: 3543-56. PMID 12865436 DOI: 10.1242/Jcs.00663 |
0.311 |
|
| 2003 |
Unger M, Weaver VM. The tissue microenvironment as an epigenetic tumor modifier. Methods in Molecular Biology (Clifton, N.J.). 223: 315-47. PMID 12777739 DOI: 10.1385/1-59259-329-1:315 |
0.449 |
|
| 2002 |
Bissell MJ, Radisky DC, Rizki A, Weaver VM, Petersen OW. The organizing principle: Microenvironmental influences in the normal and malignant breast Differentiation. 70: 537-546. PMID 12492495 DOI: 10.1046/J.1432-0436.2002.700907.X |
0.631 |
|
| 2002 |
Weaver VM, Lelièvre S, Lakins JN, Chrenek MA, Jones JCR, Giancotti F, Werb Z, Bissell MJ. β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium Cancer Cell. 2: 205-216. PMID 12242153 DOI: 10.1016/S1535-6108(02)00125-3 |
0.769 |
|
| 2002 |
Weaver VM. Membrane-associated MMP regulators: novel cell adhesion tumor suppressor proteins? Developmental Cell. 2: 6-7. PMID 11782309 DOI: 10.1016/S1534-5807(01)00117-4 |
0.436 |
|
| 2001 |
Chrenek MA, Wong P, Weaver VM. Integrins and cell adhesions as modulators of mammary cell survival and transformation Breast Cancer Research. 3: 224-229. PMID 11434873 DOI: 10.1186/Bcr300 |
0.513 |
|
| 2000 |
Gray J, Chin K, Collins C, Yaswin P, Nonet G, Kowbel D, Kuo W, Garcia E, Solorzano COd, Knowles D, Lockett S, Bissell M, Weaver V, Pinkel D, Albertson D, et al. Two molecular cytogenetic views of breast cancer Breast Cancer Research. 2: 1-2. DOI: 10.1186/Bcr195 |
0.51 |
|
| 1999 |
Guerra-Vladusic FK, Scott G, Weaver V, Vladusic EA, Tsai MS, Benz CC, Lupu R. Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3. International Journal of Oncology. 15: 883-92. PMID 10536169 DOI: 10.3892/Ijo.15.5.883 |
0.428 |
|
| 1999 |
Weaver VM, Bissell MJ. Functional Culture Models to Study Mechanisms Governing Apoptosis in Normal and Malignant Mammary Epithelial Cells Journal of Mammary Gland Biology and Neoplasia. 4: 193-201. PMID 10426398 DOI: 10.1023/A:1018781325716 |
0.633 |
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| 1998 |
Schmeichel KL, Weaver VM, Bissell MJ. Structural Cues from the Tissue Microenvironment Are Essential Determinants of the Human Mammary Epithelial Cell Phenotype Journal of Mammary Gland Biology and Neoplasia. 3: 201-213. PMID 10819528 DOI: 10.1023/A:1018751124382 |
0.601 |
|
| 1998 |
Wang F, Weaver VM, Petersen OW, Larabell CA, Dedhar S, Briand P, Lupu R, Bissell MJ. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proceedings of the National Academy of Sciences of the United States of America. 95: 14821-6. PMID 9843973 DOI: 10.1073/Pnas.95.25.14821 |
0.622 |
|
| 1998 |
Lelièvre SA, Weaver VM, Nickerson JA, Larabell CA, Bhaumik A, Petersen OW, Bissell MJ. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus Proceedings of the National Academy of Sciences of the United States of America. 95: 14711-14716. PMID 9843954 DOI: 10.1073/Pnas.95.25.14711 |
0.752 |
|
| 1998 |
Petersen OW, Ronnov-Jessen L, Weaver VM, Bissell MJ. Differentiation and cancer in the mammary gland: Shedding light on an old dichotomy Advances in Cancer Research. 75: 135-161. PMID 9709809 DOI: 10.1016/S0065-230X(08)60741-1 |
0.594 |
|
| 1997 |
Weaver VM, Petersen OW, Wang F, Larabell CA, Briand P, Damsky C, Bissell MJ. Reversion of the malignant phenotype of human breast cells in three- dimensional culture and in vivo by integrin blocking antibodies Journal of Cell Biology. 137: 231-245. PMID 9105051 DOI: 10.1083/Jcb.137.1.231 |
0.61 |
|
| 1997 |
Lelièvre S, Weaver VM, Larabell CA, Bissell MJ. Extracellular Matrix and Nuclear Matrix Interactions May Regulate Apoptosis and Tissue-Specific Gene Expression: A Concept Whose Time has Come Advances in Molecular and Cell Biology. 24: 1-55. DOI: 10.1016/S1569-2558(08)60211-8 |
0.763 |
|
| 1997 |
Weaver VM, Roskelley CD. Extracellular matrix: The central regulator of cell and tissue homeostasis Trends in Cell Biology. 7: 40-42. DOI: 10.1016/S0962-8924(97)30078-6 |
0.498 |
|
| 1996 |
Weaver VM, Fischer AH, Peterson OW, Bissell MJ. The importance of the microenvironment in breast cancer progression: Recapitulation of mammary tumorigenesis using a unique human mammary epithelial cell model and a three-dimensional culture assay Biochemistry and Cell Biology. 74: 833-851. PMID 9164652 DOI: 10.1139/O96-089 |
0.659 |
|
| 1995 |
Weaver VM, Howlett AR, Langton-Webster B, Petersen OW, Bissell MJ. The development of a functionally relevant cell culture model of progressive human breast cancer Seminars in Cancer Biology. 6: 175-184. PMID 7495986 DOI: 10.1006/Scbi.1995.0021 |
0.627 |
|
| 1993 |
Weaver VM, Welsh J. 1,25-Dihydroxycholecalciferol supplementation prevents hypocalcemia in magnesium-deficient chicks Journal of Nutrition. 123: 764-771. PMID 8463878 DOI: 10.1093/Jn/123.4.764 |
0.548 |
|
| 1991 |
Welsh J, Weaver V, Simboli-Campbell M. Regulation of renal 25(OH)D3 1 alpha-hydroxylase: signal transduction pathways Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 69: 768-770. PMID 1667975 DOI: 10.1139/O91-118 |
0.594 |
|
| 1989 |
Weaver VM, Welsh JJ. Vitamin D metabolism in magnesium deficient chicks Nutrition Research. 9: 1363-1369. DOI: 10.1016/S0271-5317(89)80161-7 |
0.549 |
|
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