Douglas G. Mashek - Publications

Affiliations: 
Nutrition University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Nutrition, Biochemistry, Pathology

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Najt CP, Adhikari S, Heden TD, Cui W, Gansemer ER, Rauckhorst AJ, Markowski TW, Higgins L, Kerr EW, Boyum MD, Alvarez J, Brunko S, Mehra D, Puchner EM, Taylor EB, ... Mashek DG, et al. Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism. Cell Reports. 42: 112435. PMID 37104088 DOI: 10.1016/j.celrep.2023.112435  0.334
2021 Lopresti MW, Cui W, Abernathy B, Fredrickson G, Barrow F, Desai AS, Revelo XS, Mashek D. Hepatic Lysosomal Acid Lipase Overexpression Worsens Hepatic Inflammation in Mice Fed a Western Diet. Journal of Lipid Research. 100133. PMID 34624333 DOI: 10.1016/j.jlr.2021.100133  0.393
2021 Heden TD, Chow LS, Hughey CC, Mashek DG. Regulation and role of glycophagy in skeletal muscle energy metabolism. Autophagy. 1-12. PMID 34506219 DOI: 10.1080/15548627.2021.1969633  0.31
2020 Mashek DG. Hepatic lipid droplets: A balancing act between energy storage and metabolic dysfunction in NAFLD. Molecular Metabolism. 101115. PMID 33186758 DOI: 10.1016/j.molmet.2020.101115  0.326
2020 O'Brien CM, Mulukutla BC, Mashek DG, Hu WS. Regulation of Metabolic Homeostasis in Cell Culture Bioprocesses. Trends in Biotechnology. 38: 1113-1127. PMID 32941791 DOI: 10.1016/J.Tibtech.2020.02.005  0.361
2020 Seibert JT, Najt CP, Heden TD, Mashek DG, Chow LS. Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond. Trends in Endocrinology and Metabolism: Tem. PMID 32917515 DOI: 10.1016/J.Tem.2020.08.002  0.302
2020 Kopczynski D, Hentschel A, Coman C, Schebb NH, Hornemann T, Mashek DG, Hartung NM, Shevchuk O, Schött HF, Lorenz K, Torta F, Burla B, Zahedi RP, Sickmann A, Kreutz MR, et al. Simple targeted assays for metabolic pathways and signaling: a powerful tool for targeted proteomics. Analytical Chemistry. PMID 32865986 DOI: 10.1021/Acs.Analchem.0C02793  0.339
2020 Cui W, Sathyanarayan A, Lopresti M, Aghajan M, Chen C, Mashek DG. Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis. Autophagy. 1-16. PMID 32070194 DOI: 10.1080/15548627.2020.1728097  0.41
2020 Zhang E, Cui W, Lopresti M, Mashek MG, Najt CP, Hu H, Mashek DG. Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting. Journal of Lipid Research. PMID 31932301 DOI: 10.1194/Jlr.Ra119000336  0.46
2020 Mashek DG, Cui W, Shang L, Najt CP. Hepatic Lipid Droplets in Liver Function and Disease Liver. 245-254. DOI: 10.1002/9781119436812.Ch21  0.392
2019 Najt CP, Khan SA, Heden TD, Witthuhn BA, Perez M, Heier JL, Mead LE, Franklin MP, Karanja KK, Graham MJ, Mashek MT, Bernlohr DA, Parker L, Chow LS, Mashek DG. Lipid Droplet-Derived Monounsaturated Fatty Acids Traffic via PLIN5 to Allosterically Activate SIRT1. Molecular Cell. PMID 31901447 DOI: 10.1016/J.Molcel.2019.12.003  0.486
2019 Nerstedt A, Kurhe Y, Cansby E, Caputo M, Gao L, Vorontsov E, Stahlman M, Nuñez-Durán E, Boren J, Marschall HU, Mashek DG, Saunders DN, Sihlbom C, Hoy AJ, Mahlapuu M. Lipid Droplet-Associated Kinase STK25 Regulates Peroxisomal Activity and Metabolic Stress Response in Steatotic Liver. Journal of Lipid Research. PMID 31857389 DOI: 10.1194/Jlr.Ra119000316  0.465
2019 Shang L, Mashek DG. The underpinnings of PNPLA3-mediated fatty liver emerge. Hepatology (Baltimore, Md.). PMID 31378994 DOI: 10.1002/Hep.30888  0.377
2019 Josephrajan A, Hertzel AV, Bohm EK, McBurney MW, Ichiro-Imai S, Mashek D, Kim DH, Bernlohr DA. Unconventional Secretion Of Adipocyte Fatty Acid Binding Protein 4 Is Mediated By Autophagic Proteins In a Sirtuin-1 Dependent Manner. Diabetes. PMID 31171562 DOI: 10.2337/Db18-1367  0.453
2019 Zhang E, Najt CP, Hu H, Mashek DG. Hepatic perilipin 5 promotes lipophagy and alters lipid droplet and mitochondrial dynamics The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.490.19  0.357
2018 Muratore KA, Najt CP, Livezey NM, Marti J, Mashek DG, Arriaga EA. Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis. Analytical and Bioanalytical Chemistry. PMID 29663061 DOI: 10.1007/S00216-018-1016-8  0.37
2017 Ploeger JM, Manivel JC, Boatner LN, Mashek DG. Caloric restriction prevents carcinogen-initiated liver cancer in mice. Cancer Prevention Research (Philadelphia, Pa.). PMID 28847977 DOI: 10.1158/1940-6207.Capr-17-0174  0.409
2017 Schulze RJ, Sathyanarayan A, Mashek DG. Breaking fat: The regulation and mechanisms of lipophagy. Biochimica Et Biophysica Acta. PMID 28642194 DOI: 10.1016/J.Bbalip.2017.06.008  0.361
2017 Franklin MP, Sathyanarayan A, Mashek DG. Acyl-CoA Thioesterase 1 (ACOT1) Regulates PPAR〈 to Couple Fatty Acid Flux with Oxidative Capacity During Fasting. Diabetes. PMID 28607105 DOI: 10.2337/Db16-1519  0.478
2017 Shepherd SO, Strauss JA, Wang Q, Dube JJ, Goodpaster B, Mashek DG, Chow LS. Training alters the distribution of perilipin proteins in muscle following acute free fatty acid exposure. The Journal of Physiology. PMID 28560826 DOI: 10.1113/Jp274374  0.323
2017 Chow LS, Mashek DG, Wang Q, Shepherd SO, Goodpaster BH, Dube JJ. Effect of acute physiological free fatty acid elevation in the context of hyperinsulinemia on fiber type specific IMCL accumulation. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00209.2017. PMID 28450549 DOI: 10.1152/Japplphysiol.00209.2017  0.317
2017 Sathyanarayan A, Mashek MT, Mashek DG. ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism. Cell Reports. 19: 1-9. PMID 28380348 DOI: 10.1016/J.Celrep.2017.03.026  0.498
2016 Kamarajugadda S, Becker JR, Hanse EA, Mashek DG, Mashek MT, Hendrickson AM, Mullany LK, Albrecht JH. Cyclin D1 represses peroxisome proliferator-activated receptor alpha and inhibits fatty acid oxidation. Oncotarget. PMID 27351284 DOI: 10.18632/Oncotarget.10274  0.407
2016 Mulukutla BC, Yongky A, Le T, Mashek DG, Hu WS. Regulation of Glucose Metabolism - A Perspective From Cell Bioprocessing. Trends in Biotechnology. PMID 27265890 DOI: 10.1016/J.Tibtech.2016.04.012  0.372
2016 Zhang W, Bu SY, Mashek MT, O-Sullivan I, Sibai Z, Khan SA, Ilkayeva O, Newgard CB, Mashek DG, Unterman TG. Integrated Regulation of Hepatic Lipid and Glucose Metabolism by Adipose Triacylglycerol Lipase and FoxO Proteins. Cell Reports. PMID 27050511 DOI: 10.1016/J.Celrep.2016.03.021  0.488
2016 Bowman TA, O'Keeffe KR, D'Aquila T, Yan QW, Griffin JD, Killion EA, Salter DM, Mashek DG, Buhman KK, Greenberg AS. Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption. Molecular Metabolism. 5: 210-20. PMID 26977393 DOI: 10.1016/J.Molmet.2016.01.001  0.498
2016 Sathyanarayan A, Mashek MT, Mashek DG. Hepatic ATGL manipulation regulates lipid metabolism through altered autophagy The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.1127.1  0.46
2015 Khan SA, Wollaston-Hayden EE, Markowski TW, Higgins L, Mashek DG. Quantitative analysis of the murine lipid droplet-associated proteome during diet-induced hepatic steatosis. Journal of Lipid Research. PMID 26416795 DOI: 10.1194/Jlr.M056812  0.465
2015 Mashek DG, Khan SA, Sathyanarayan A, Ploeger JM, Franklin MP. Hepatic lipid droplet biology: Getting to the root of fatty liver. Hepatology (Baltimore, Md.). PMID 25854913 DOI: 10.1002/Hep.27839  0.451
2015 Khan SA, Sathyanarayan A, Mashek MT, Ong KT, Wollaston-Hayden EE, Mashek DG. ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling. Diabetes. 64: 418-26. PMID 25614670 DOI: 10.2337/Db14-0325  0.742
2015 Sathyanarayan A, Khan S, Mashek M, Mashek D. ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1a/PPAR-a signaling The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.885.24  0.315
2014 Zhang Y, Guo H, Deis JA, Mashek MG, Zhao M, Ariyakumar D, Armien AG, Bernlohr DA, Mashek DG, Chen X. Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanism. The Journal of Biological Chemistry. 289: 22063-77. PMID 24917675 DOI: 10.1074/Jbc.M114.559104  0.418
2014 Chow LS, Mashek DG, Austin E, Eberly LE, Persson XM, Mashek MT, Seaquist ER, Jensen MD. Training status diverges muscle diacylglycerol accumulation during free fatty acid elevation. American Journal of Physiology. Endocrinology and Metabolism. 307: E124-31. PMID 24844260 DOI: 10.1152/Ajpendo.00166.2014  0.371
2014 Ong KT, Mashek MT, Davidson NO, Mashek DG. Hepatic ATGL mediates PPAR-α signaling and fatty acid channeling through an L-FABP independent mechanism. Journal of Lipid Research. 55: 808-15. PMID 24610891 DOI: 10.1194/Jlr.M039867  0.75
2014 Mashek DG, Greenberg AS. Serum TAG analysis differentiates between genetic and obesity-associated NAFLD. Diabetes. 63: 42-4. PMID 24357693 DOI: 10.2337/Db13-1500  0.401
2013 Mashek DG. Hepatic fatty acid trafficking: multiple forks in the road. Advances in Nutrition (Bethesda, Md.). 4: 697-710. PMID 24228201 DOI: 10.3945/An.113.004648  0.482
2013 Nelson DR, Mengistu S, Ranum P, Celio G, Mashek M, Mashek D, Lefebvre PA. New lipid-producing, cold-tolerant yellow-green alga isolated from the Rocky Mountains of Colorado. Biotechnology Progress. 29: 853-61. PMID 23754623 DOI: 10.1002/Btpr.1755  0.315
2013 Mamedova LK, Yuan K, Laudick AN, Fleming SD, Mashek DG, Bradford BJ. Toll-like receptor 4 signaling is required for induction of gluconeogenic gene expression by palmitate in human hepatic carcinoma cells. The Journal of Nutritional Biochemistry. 24: 1499-507. PMID 23465595 DOI: 10.1016/J.Jnutbio.2012.12.009  0.386
2013 Ong KT, Mashek MT, Bu SY, Mashek DG. Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 313-21. PMID 22993196 DOI: 10.1096/Fj.12-213454  0.743
2013 Hansen TJ, Hondzo M, Mashek MT, Mashek DG, Lefebvre PA. Algal swimming velocities signal fatty acid accumulation. Biotechnology and Bioengineering. 110: 143-52. PMID 22833390 DOI: 10.1002/Bit.24619  0.362
2012 Zhang W, Zhang X, Wang H, Guo X, Li H, Wang Y, Xu X, Tan L, Mashek MT, Zhang C, Chen Y, Mashek DG, Foretz M, Zhu C, Zhou H, et al. AMP-activated protein kinase α1 protects against diet-induced insulin resistance and obesity. Diabetes. 61: 3114-25. PMID 22829451 DOI: 10.2337/Db11-1373  0.399
2012 Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Ong KT, Woo SL, Walzem RL, Mashek DG, Dong H, Lu F, Wei L, Huo Y, Wu C. Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice. Plos One. 7: e39286. PMID 22768070 DOI: 10.1371/Journal.Pone.0039286  0.769
2012 Hanse EA, Mashek DG, Becker JR, Solmonson AD, Mullany LK, Mashek MT, Towle HC, Chau AT, Albrecht JH. Cyclin D1 inhibits hepatic lipogenesis via repression of carbohydrate response element binding protein and hepatocyte nuclear factor 4α. Cell Cycle (Georgetown, Tex.). 11: 2681-90. PMID 22751438 DOI: 10.4161/Cc.21019  0.382
2012 Huo Y, Guo X, Li H, Xu H, Halim V, Zhang W, Wang H, Fan YY, Ong KT, Woo SL, Chapkin RS, Mashek DG, Chen Y, Dong H, Lu F, et al. Targeted overexpression of inducible 6-phosphofructo-2-kinase in adipose tissue increases fat deposition but protects against diet-induced insulin resistance and inflammatory responses. The Journal of Biological Chemistry. 287: 21492-500. PMID 22556414 DOI: 10.1074/Jbc.M112.370379  0.755
2011 Greenberg AS, Coleman RA, Kraemer FB, McManaman JL, Obin MS, Puri V, Yan QW, Miyoshi H, Mashek DG. The role of lipid droplets in metabolic disease in rodents and humans. The Journal of Clinical Investigation. 121: 2102-10. PMID 21633178 DOI: 10.1172/Jci46069  0.588
2011 Coleman RA, Mashek DG. Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling. Chemical Reviews. 111: 6359-86. PMID 21627334 DOI: 10.1021/Cr100404W  0.645
2011 Stapleton CM, Mashek DG, Wang S, Nagle CA, Cline GW, Thuillier P, Leesnitzer LM, Li LO, Stimmel JB, Shulman GI, Coleman RA. Lysophosphatidic acid activates peroxisome proliferator activated receptor-γ in CHO cells that over-express glycerol 3-phosphate acyltransferase-1. Plos One. 6: e18932. PMID 21533082 DOI: 10.1371/Journal.Pone.0018932  0.727
2011 Jin D, Guo H, Bu SY, Zhang Y, Hannaford J, Mashek DG, Chen X. Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 754-64. PMID 20974668 DOI: 10.1096/Fj.10-165175  0.478
2011 Ong KT, Mashek MT, Bu SY, Greenberg AS, Mashek DG. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology (Baltimore, Md.). 53: 116-26. PMID 20967758 DOI: 10.1002/Hep.24006  0.79
2011 Schwinkendorf DR, Tsatsos NG, Gosnell BA, Mashek DG. Effects of central administration of distinct fatty acids on hypothalamic neuropeptide expression and energy metabolism. International Journal of Obesity (2005). 35: 336-44. PMID 20714328 DOI: 10.1038/Ijo.2010.159  0.402
2010 Bu SY, Mashek DG. Hepatic long-chain acyl-CoA synthetase 5 mediates fatty acid channeling between anabolic and catabolic pathways. Journal of Lipid Research. 51: 3270-80. PMID 20798351 DOI: 10.1194/Jlr.M009407  0.542
2010 Aipoalani DL, O'Callaghan BL, Mashek DG, Mariash CN, Towle HC. Overlapping roles of the glucose-responsive genes, S14 and S14R, in hepatic lipogenesis. Endocrinology. 151: 2071-7. PMID 20233797 DOI: 10.1210/En.2009-1058  0.409
2009 Bu SY, Mashek MT, Mashek DG. Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity. The Journal of Biological Chemistry. 284: 30474-83. PMID 19737935 DOI: 10.1074/Jbc.M109.036665  0.534
2009 Sapiro JM, Mashek MT, Greenberg AS, Mashek DG. Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity. Journal of Lipid Research. 50: 1621-9. PMID 19304987 DOI: 10.1194/Jlr.M800614-Jlr200  0.469
2007 Mashek DG, Li LO, Coleman RA. Long-chain acyl-CoA synthetases and fatty acid channeling. Future Lipidology. 2: 465-476. PMID 20354580 DOI: 10.2217/17460875.2.4.465  0.651
2007 Wang S, Lee DP, Gong N, Schwerbrock NM, Mashek DG, Gonzalez-Baró MR, Stapleton C, Li LO, Lewin TM, Coleman RA. Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2). Archives of Biochemistry and Biophysics. 465: 347-58. PMID 17689486 DOI: 10.1016/J.Abb.2007.06.033  0.623
2006 Li LO, Mashek DG, An J, Doughman SD, Newgard CB, Coleman RA. Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. The Journal of Biological Chemistry. 281: 37246-55. PMID 17028193 DOI: 10.1074/Jbc.M604427200  0.635
2006 Mashek DG, Li LO, Coleman RA. Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet. Journal of Lipid Research. 47: 2004-10. PMID 16772660 DOI: 10.1194/Jlr.M600150-Jlr200  0.607
2006 Mashek DG, Coleman RA. Cellular fatty acid uptake: the contribution of metabolism. Current Opinion in Lipidology. 17: 274-8. PMID 16680032 DOI: 10.1097/01.Mol.0000226119.20307.2B  0.62
2006 Mashek DG, McKenzie MA, Van Horn CG, Coleman RA. Rat long chain acyl-CoA synthetase 5 increases fatty acid uptake and partitioning to cellular triacylglycerol in McArdle-RH7777 cells. The Journal of Biological Chemistry. 281: 945-50. PMID 16263710 DOI: 10.1074/Jbc.M507646200  0.618
2005 Mashek DG, Bertics SJ, Grummer RR. Effects of Intravenous Triacylglycerol Emulsions on Hepatic Metabolism and Blood Metabolites in Fasted Dairy Cows Journal of Dairy Science. 88: 100-109. PMID 15591372 DOI: 10.3168/Jds.S0022-0302(05)72667-9  0.333
2004 Mashek DG, Bornfeldt KE, Coleman RA, Berger J, Bernlohr DA, Black P, DiRusso CC, Farber SA, Guo W, Hashimoto N, Khodiyar V, Kuypers FA, Maltais LJ, Nebert DW, Renieri A, et al. Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family. Journal of Lipid Research. 45: 1958-61. PMID 15292367 DOI: 10.1194/Jlr.E400002-Jlr200  0.512
2004 Mashek D, Grummer RR. Effects of conjugated linoleic acid isomers on lipid metabolism and gluconeogenesis in monolayer cultures of bovine hepatocytes. Journal of Dairy Science. 87: 67-72. PMID 14765812 DOI: 10.3168/Jds.S0022-0302(04)73143-4  0.408
2003 Mashek DG, Grummer RR. Effects of long chain fatty acids on lipid and glucose metabolism in monolayer cultures of bovine hepatocytes. Journal of Dairy Science. 86: 2390-2396. PMID 12906057 DOI: 10.3168/Jds.S0022-0302(03)73833-8  0.337
2003 Mashek D, Grummer RR. Short communication: Net uptake of nonesterified long chain fatty acids by the perfused caudate lobe of the caprine liver. Journal of Dairy Science. 86: 1218-1220. PMID 12741546 DOI: 10.3168/Jds.S0022-0302(03)73705-9  0.403
2002 Mashek DG, Bertics SJ, Grummer RR. Metabolic fate of long-chain unsaturated fatty acids and their effects on palmitic acid metabolism and gluconeogenesis in bovine hepatocytes. Journal of Dairy Science. 85: 2283-2289. PMID 12362461 DOI: 10.3168/Jds.S0022-0302(02)74308-7  0.394
2002 Andersen JB, Mashek DG, Larsen T, Nielsen MO, Ingvartsen KL. Effects of hyperinsulinaemia under euglycaemic condition on liver fat metabolism in dairy cows in early and mid-lactation Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine. 49: 65-71. PMID 11958469 DOI: 10.1046/J.1439-0442.2002.Jv417.X  0.459
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