Ake Lernmark - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Immunology, Medicine and Surgery, Pathology, Molecular Biology

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Year Citation  Score
2024 Zhao LP, Papadopoulos GK, Skyler JS, Pugliese A, Parikh HM, Kwok WW, Lybrand TP, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07). Diabetes Care. PMID 38498185 DOI: 10.2337/dc23-1947  0.369
2024 Hakola L, Mramba LK, Uusitalo U, Andrén Aronsson C, Hummel S, Niinistö S, Erlund I, Yang J, Rewers MJ, Akolkar B, McIndoe RA, Rich SS, Hagopian WA, Ziegler A, Lernmark Å, et al. Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study. European Journal of Nutrition. PMID 38413484 DOI: 10.1007/s00394-024-03346-6  0.319
2023 Lönnrot M, Lynch KF, Rewers M, Lernmark Å, Vehik K, Akolkar B, Hagopian W, Krischer J, McIndoe RA, Toppari J, Ziegler AG, Petrosino JF, Lloyd R, Hyöty H. Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study. Diabetes Care. PMID 37607456 DOI: 10.2337/dc23-0518  0.304
2023 Krischer JP, Lernmark Å, Hagopian WA, Rewers MJ, McIndoe R, Toppari J, Ziegler AG, Akolkar B. SARS-CoV-2 - No Increased Islet Autoimmunity or Type 1 Diabetes in Teens. The New England Journal of Medicine. 389: 474-475. PMID 37530831 DOI: 10.1056/NEJMc2216477  0.407
2023 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Lernmark Å, Metzger BE, Nathan DM, Kirkman MS. Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Clinical Chemistry. PMID 37473453 DOI: 10.1093/clinchem/hvad080  0.305
2023 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Lernmark Å, Metzger BE, Nathan DM, Kirkman MS. Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Diabetes Care. PMID 37471273 DOI: 10.2337/dci23-0036  0.305
2023 Lernmark Å, Akolkar B, Hagopian W, Krischer J, McIndoe R, Rewers M, Toppari J, Vehik K, Ziegler AG. Possible heterogeneity of initial pancreatic islet beta-cell autoimmunity heralding type 1 diabetes. Journal of Internal Medicine. PMID 37143363 DOI: 10.1111/joim.13648  0.447
2023 Liu X, Johnson SB, Lynch KF, Cordan K, Pate R, Butterworth MD, Lernmark Å, Hagopian WA, Rewers MJ, McIndoe RA, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Yang J. Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5-15-Year-Old Children Followed in the TEDDY Study. Diabetes Care. PMID 37141102 DOI: 10.2337/dc23-0036  0.336
2022 Vehik K, Boulware D, Killian M, Rewers M, McIndoe R, Toppari J, Lernmark Å, Akolkar B, Ziegler AG, Rodriguez H, Schatz DA, Krischer JP, Hagopian W. Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests. Diabetes Care. 45: 2342-2349. PMID 36150054 DOI: 10.2337/dc22-0828  0.386
2022 Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study. Diabetes Care. 45: 2271-2281. PMID 36150053 DOI: 10.2337/dc21-2612  0.385
2022 Kwon BC, Achenbach P, Anand V, Frohnert BI, Hagopian W, Hu J, Koski E, Lernmark Å, Lou O, Martin F, Ng K, Toppari J, Veijola R. Islet Autoantibody Levels Differentiate Progression Trajectories in Individuals with Presymptomatic Type 1 Diabetes. Diabetes. PMID 36112006 DOI: 10.2337/db22-0360  0.381
2022 Salami F, Tamura R, You L, Lernmark Å, Larsson HE, Lundgren M, Krischer J, Ziegler AG, Toppari J, Veijola R, Rewers M, Haller MJ, Hagopian W, Akolkar B, Törn C. HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children. Pediatric Diabetes. PMID 36082496 DOI: 10.1111/pedi.13413  0.433
2022 Andersson Svärd A, Benatti E, Lundgren M, Lernmark Å, Maziarz M, Elding Larsson H. Possible Relationship between the HLA-DRA1 Intron Haplotype of Three Single-Nucleotide Polymorphisms in Intron 1 of the HLA-DRA1 Gene and Autoantibodies in Children at Increased Genetic Risk for Autoimmune Type 1 Diabetes. Immunohorizons. 6: 614-629. PMID 35981747 DOI: 10.4049/immunohorizons.2200039  0.317
2022 Zhao LP, Skyler J, Papadopoulos GK, Pugliese A, Najera JA, Bondinas GP, Moustakas AK, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Association of HLA-DQ Heterodimer Residues -18β and β57 With Progression From Islet Autoimmunity to Diabetes in the Diabetes Prevention Trial-Type 1. Diabetes Care. PMID 35621697 DOI: 10.2337/dc21-1628  0.395
2022 Kwon BC, Anand V, Achenbach P, Dunne JL, Hagopian W, Hu J, Koski E, Lernmark Å, Lundgren M, Ng K, Toppari J, Veijola R, Frohnert BI. Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories. Nature Communications. 13: 1514. PMID 35314671 DOI: 10.1038/s41467-022-28909-1  0.363
2022 Jacobsen LM, Vehik K, Veijola R, Warncke K, Toppari J, Steck AK, Gesualdo P, Akolkar B, Lundgren M, Hagopian WA, She JX, Rewers M, Ziegler AG, Krischer JP, Larsson HE, et al. Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study. Diabetes Care. PMID 35043162 DOI: 10.2337/dc21-0422  0.378
2021 Lundstig A, McDonald SL, Maziarz M, Weldon WC, Vaziri-Sani F, Lernmark Å, Nilsson AL. Erratum: Neutralizing Ljungan virus antibodies in children with newly diagnosed type 1 diabetes. The Journal of General Virology. 102. PMID 34242157 DOI: 10.1099/jgv.0.001621  0.322
2021 Lernmark Å. Etiology of Autoimmune Islet Disease: Timing Is Everything. Diabetes. PMID 34155043 DOI: 10.2337/dbi18-0034  0.401
2021 Zhao LP, Papadopoulos GK, Lybrand TP, Moustakas AK, Bondinas GP, Carlsson A, Larsson HE, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, et al. The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes. Ebiomedicine. 69: 103431. PMID 34153873 DOI: 10.1016/j.ebiom.2021.103431  0.325
2021 Lundstig A, McDonald SL, Maziarz M, Weldon WC, Vaziri-Sani F, Lernmark Å, Nilsson AL. Neutralizing Ljungan virus antibodies in children with newly diagnosed type 1 diabetes. The Journal of General Virology. 102. PMID 34020728 DOI: 10.1099/jgv.0.001602  0.421
2021 Bogdani M, Faxius L, Fex M, Ramelius A, Wernersson A, Mordes JP, Blankenhorn EP, Lernmark Å. The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DR Rats. Frontiers in Endocrinology. 12: 629242. PMID 33815287 DOI: 10.3389/fendo.2021.629242  0.339
2021 Xhonneux LP, Knight O, Lernmark Å, Bonifacio E, Hagopian WA, Rewers MJ, She JX, Toppari J, Parikh H, Smith KGC, Ziegler AG, Akolkar B, Krischer JP, McKinney EF. Transcriptional networks in at-risk individuals identify signatures of type 1 diabetes progression. Science Translational Medicine. 13. PMID 33790023 DOI: 10.1126/scitranslmed.abd5666  0.382
2021 Bonifacio E, Weiß A, Winkler C, Hippich M, Rewers MJ, Toppari J, Lernmark Å, She JX, Hagopian WA, Krischer JP, Vehik K, Schatz DA, Akolkar B, Ziegler AG. An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. PMID 33627366 DOI: 10.2337/dc20-2122  0.367
2021 Johnson SB, Lynch KF, Roth R, Lundgren M, Parikh HM, Akolkar B, Hagopian W, Krischer J, Rewers M, She JX, Toppari J, Ziegler AG, Lernmark Å. First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child's genetic risk. Diabetologia. PMID 33404683 DOI: 10.1007/s00125-020-05344-9  0.312
2020 Andersson Svärd A, Kaur S, Trôst K, Suvitaival T, Lernmark Å, Maziarz M, Pociot F, Overgaard AJ. Characterization of plasma lipidomics in adolescent subjects with increased risk for type 1 diabetes in the DiPiS cohort. Metabolomics : Official Journal of the Metabolomic Society. 16: 109. PMID 33033923 DOI: 10.1007/s11306-020-01730-x  0.367
2020 Zhao LP, Papadopoulos GK, Kwok WW, Moustakas AK, Bondinas GP, Carlsson A, Larsson HE, Ludvigsson J, Marcus C, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Next Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes. Diabetes. PMID 32868339 DOI: 10.2337/Db20-0374  0.345
2020 Ferrat LA, Vehik K, Sharp SA, Lernmark Å, Rewers MJ, She JX, Ziegler AG, Toppari J, Akolkar B, Krischer JP, Weedon MN, Oram RA, Hagopian WA. A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nature Medicine. 26: 1247-1255. PMID 32770166 DOI: 10.1038/S41591-020-0930-4  0.42
2020 Vehik K, Bonifacio E, Lernmark A, Yu L, Williams A, Schatz D, Rewers M, She JX, Toppari J, Hagopian W, Akolkar B, Ziegler AG, Krischer JP. Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study. Diabetes Care. PMID 32641373 DOI: 10.2337/Dc19-2547  0.501
2020 Widén C, Holmer H, Sättlin S, Renvert S, Lernmark Å, Persson GR. Periodontal conditions, retinopathy, and serum markers in individuals with type 1 diabetes. Journal of Periodontology. PMID 32484239 DOI: 10.1002/Jper.19-0641  0.497
2020 Zhao LP, Papadopoulos GK, Kwok WW, Moustakas AK, Bondinas GP, Larsson HE, Ludvigsson J, Marcus C, Samuelsson U, Wang R, Pyo CW, Nelson WC, Geraghty DE, Lernmark Å. Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association with the Risk of Type 1 Diabetes in DQ2 and DQ8 Children. Diabetes. PMID 32245799 DOI: 10.2337/Db20-0075  0.315
2020 Lind A, Eriksson D, Akel O, Ramelius A, Palm L, Lernmark Å, Kämpe O, Elding Larsson H, Landegren N. Screening for autoantibody targets in post-vaccination narcolepsy using proteome arrays. Scandinavian Journal of Immunology. e12864. PMID 32056243 DOI: 10.1111/Sji.12864  0.304
2020 Li Q, Parikh H, Butterworth MD, Lernmark Å, Hagopian W, Rewers M, She JX, Toppari J, Ziegler AG, Akolkar B, Fiehn O, Fan S, Krischer JP. Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study. Diabetes. PMID 32029481 DOI: 10.2337/Db19-0756  0.373
2020 Bogdani M, Speake C, Dufort MJ, Johnson PY, Larmore MJ, Day AJ, Wight TN, Lernmark Å, Greenbaum CJ. Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates. Diabetologia. PMID 31907557 DOI: 10.1007/S00125-019-05066-7  0.413
2019 Vehik K, Lynch KF, Wong MC, Tian X, Ross MC, Gibbs RA, Ajami NJ, Petrosino JF, Rewers M, Toppari J, Ziegler AG, She JX, Lernmark A, Akolkar B, Hagopian WA, et al. Prospective virome analyses in young children at increased genetic risk for type 1 diabetes. Nature Medicine. PMID 31792456 DOI: 10.1038/S41591-019-0667-0  0.43
2019 Mattila M, Erlund I, Lee HS, Niinistö S, Uusitalo U, Andrén Aronsson C, Hummel S, Parikh H, Rich SS, Hagopian W, Toppari J, Lernmark Å, Ziegler AG, Rewers M, Krischer JP, et al. Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study. Diabetologia. PMID 31728565 DOI: 10.1007/S00125-019-05028-Z  0.462
2019 Carlsson A, Shepherd M, Ellard S, Weedon M, Lernmark Å, Forsander G, Colclough K, Brahimi Q, Valtonen-Andre C, Ivarsson SA, Elding Larsson H, Samuelsson U, Örtqvist E, Groop L, Ludvigsson J, et al. Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study. Diabetes Care. PMID 31704690 DOI: 10.2337/Dc19-0747  0.487
2019 Johnson RK, Vanderlinden L, DeFelice BC, Kechris K, Uusitalo U, Fiehn O, Sontag M, Crume T, Beyerlein A, Lernmark Å, Toppari J, Ziegler AG, She JX, Hagopian W, Rewers M, et al. Metabolite-related dietary patterns and the development of islet autoimmunity. Scientific Reports. 9: 14819. PMID 31616039 DOI: 10.1038/S41598-019-51251-4  0.364
2019 Lind A, Akel O, Wallenius M, Ramelius A, Maziarz M, Zhao LP, Geraghty DE, Palm L, Lernmark Å, Larsson HE. HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy. Plos One. 14: e0222882. PMID 31577807 DOI: 10.1371/Journal.Pone.0222882  0.304
2019 Zhao LP, Papadopoulos GK, Kwok B, Xu B, Kong M, Moustakas AK, Bondinas GP, Carlsson A, Elding-Larsson H, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Wang R, Pyo CW, et al. Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4 and 5 Include Potentially "Causal Residues" Responsible for the Risk of Childhood Type 1 Diabetes. Diabetes. PMID 31127057 DOI: 10.2337/Db19-0273  0.396
2019 Krischer JP, Liu X, Vehik K, Akolkar B, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Lernmark Å. Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report. Diabetes Care. PMID 30967432 DOI: 10.2337/Dc18-2282  0.482
2019 Aydemir Ö, Noble JA, Bailey J, Lernmark Å, Marsh P, Svärd AA, Bearoff F, Blankenhorn EP, Mordes JP. Genetic Variation Within the Gene Modulates Susceptibility to Type 1 Diabetes in HLA-DR3 Homozygotes. Diabetes. PMID 30962219 DOI: 10.2337/Db18-1128  0.399
2019 Dunne JL, Richardson SJ, Atkinson MA, Craig ME, Dahl-Jørgensen K, Flodström-Tullberg M, Hyöty H, Insel RA, Lernmark Å, Lloyd RE, Morgan NG, Pugliese A. Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes. Diabetologia. PMID 30675626 DOI: 10.1007/S00125-019-4811-7  0.468
2019 Hippich M, Beyerlein A, Hagopian WA, Krischer JP, Vehik K, Knoop J, Winker C, Toppari J, Lernmark Å, Rewers MJ, Steck AK, She JX, Akolkar B, Robertson CC, Onengut-Gumuscu S, et al. Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families. Diabetes. PMID 30655385 DOI: 10.2337/Db18-0882  0.416
2019 Fex G, Lernmark A. Effect of D-glucose on the incorporation of 32P into phospholipids of mouse pancreatic islets. Febs Letters. 25: 287-291. PMID 11946771 DOI: 10.1016/0014-5793(72)80505-2  0.333
2019 Ferrat LA, Vehik K, Sharp SA, Lernmark Å, Ziegler A, Rewers M, She J, Toppari J, Akolkar B, Krischer J, Weedon MN, Rich SS, Oram RA, Hagopian W. 210-OR: A Combined Method Improves Risk Prediction for Childhood Type 1 Diabetes in the TEDDY Study Diabetes. 68. DOI: 10.2337/Db19-210-Or  0.357
2019 LYNCH KF, FENG T, QIAN X, HAGOPIAN W, LERNMARK Å, ZIEGLER A, TOPPARI J, REWERS M, SHE J, SCHATZ D, AKOLKAR B, KRISCHER J, HUANG S, VEHIK K. 1682-P: A Rule-Based Discovery of Gene-Environment Interactions on Risk of Islet Autoimmunity: TEDDY Study Diabetes. 68: 1682-P. DOI: 10.2337/Db19-1682-P  0.362
2019 Anand V, Liu B, Ghalwash M, Koski E, Ng K, Dunne JL, Hagopian W, Lundgren M, Lernmark Å, Ilonen J, Veijola R, Rewers M. 1345-P: Presymptomatic and Clinical T1D in The U.S., Sweden, and Finland: Joint Analysis of Four Birth Cohort Studies Diabetes. 68. DOI: 10.2337/Db19-1345-P  0.337
2018 Cerqueiro Bybrant M, Grahnquist L, Örtqvist E, Andersson C, Forsander G, Elding Larsson H, Lernmark Å, Ludvigsson J, Marcus C, Carlsson A, Ivarsson SA. Tissue transglutaminase autoantibodies in children with newly diagnosed type 1 diabetes are related to human leukocyte antigen but not to islet autoantibodies: A Swedish nationwide prospective population-based cohort study. Autoimmunity. 1-7. PMID 30444426 DOI: 10.1080/08916934.2018.1494160  0.479
2018 Stewart CJ, Ajami NJ, O'Brien JL, Hutchinson DS, Smith DP, Wong MC, Ross MC, Lloyd RE, Doddapaneni H, Metcalf GA, Muzny D, Gibbs RA, Vatanen T, Huttenhower C, Xavier RJ, ... ... Lernmark A, et al. Temporal development of the gut microbiome in early childhood from the TEDDY study. Nature. 562: 583-588. PMID 30356187 DOI: 10.1038/S41586-018-0617-X  0.367
2018 Vatanen T, Franzosa EA, Schwager R, Tripathi S, Arthur TD, Vehik K, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Stewart CJ, et al. The human gut microbiome in early-onset type 1 diabetes from the TEDDY study. Nature. 562: 589-594. PMID 30356183 DOI: 10.1038/S41586-018-0620-2  0.425
2018 Rewers M, Hyöty H, Lernmark Å, Hagopian W, She JX, Schatz D, Ziegler AG, Toppari J, Akolkar B, Krischer J. The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update. Current Diabetes Reports. 18: 136. PMID 30353256 DOI: 10.1007/S11892-018-1113-2  0.512
2018 Endesfelder D, Castell WZ, Bonifacio E, Rewers M, Hagopian WA, She JX, Lernmark Å, Toppari J, Vehik K, Williams AJK, Yu L, Akolkar B, Krischer JP, Ziegler AG, Achenbach P, et al. Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children. Diabetes. PMID 30305370 DOI: 10.2337/Db18-0594  0.477
2018 Beyerlein A, Bonifacio E, Vehik K, Hippich M, Winkler C, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, She JX, Toppari J, Akolkar B, Rich SS, et al. Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study. Journal of Medical Genetics. PMID 30287597 DOI: 10.1136/Jmedgenet-2018-105532  0.455
2018 Hampe CS, Radtke JR, Wester A, Carlsson A, Cedervall E, Jönsson B, Ivarsson SA, Elding Larsson H, Larsson K, Lindberg B, Neiderud J, Rolandsson O, Lernmark Å. Reduced display of conformational epitopes in the N-terminal truncated GAD65 isoform: relevance for people with stiff person syndrome or DQ8/8-positive Type 1 diabetes mellitus. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 30264481 DOI: 10.1111/Dme.13827  0.424
2018 Salami F, Lee HS, Freyhult E, Larsson HE, Lernmark Å, Törn C. Reduction in White Blood Cell, Neutrophil and Red Blood Cell counts Related to Gender, HLA and Islet Autoantibodies in Swedish TEDDY Children at Increased Risk for Type 1 Diabetes. Diabetes. PMID 30104249 DOI: 10.2337/Db18-0355  0.416
2018 Persson M, Becker C, Larsson HE, Lernmark Å, Forsander G, Ivarsson SA, Ludvigsson J, Samuelsson U, Marcus C, Carlsson A. The Better Diabetes Diagnosis (BDD) study - A review of a nationwide prospective cohort study in Sweden. Diabetes Research and Clinical Practice. 140: 236-244. PMID 29626585 DOI: 10.1016/J.Diabres.2018.03.057  0.501
2018 Bonifacio E, Beyerlein A, Hippich M, Winkler C, Vehik K, Weedon MN, Laimighofer M, Hattersley AT, Krumsiek J, Frohnert BI, Steck AK, Hagopian WA, Krischer JP, Lernmark Å, Rewers MJ, et al. Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children. Plos Medicine. 15: e1002548. PMID 29614081 DOI: 10.1371/Journal.Pmed.1002548  0.457
2018 Lind A, Lynch KF, Lundgren M, Lernmark Å, Almgren P, Ramelius A, Puustinen L, Hyöty H, Lundstig A. First trimester enterovirus IgM and beta cell autoantibodies in mothers to children affected by type 1 diabetes autoimmunity before 7 years of age. Journal of Reproductive Immunology. 127: 1-6. PMID 29550618 DOI: 10.1016/J.Jri.2018.02.004  0.431
2018 Ahlqvist E, Storm P, Käräjämäki A, Martinell M, Dorkhan M, Carlsson A, Vikman P, Prasad RB, Aly DM, Almgren P, Wessman Y, Shaat N, Spégel P, Mulder H, Lindholm E, et al. Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables. The Lancet. Diabetes & Endocrinology. PMID 29503172 DOI: 10.1016/S2213-8587(18)30051-2  0.478
2018 Leslie RD, Lernmark Å. Genetic risk scores in adult-onset type 1 diabetes. The Lancet. Diabetes & Endocrinology. 6: 168-169. PMID 29475495 DOI: 10.1016/S2213-8587(18)30039-1  0.419
2018 Sharma A, Liu X, Hadley D, Hagopian W, Chen WM, Onengut-Gumuscu S, Törn C, Steck AK, Frohnert BI, Rewers M, Ziegler AG, Lernmark Å, Toppari J, Krischer JP, Akolkar B, et al. Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort. Journal of Autoimmunity. PMID 29310926 DOI: 10.1016/J.Jaut.2017.12.008  0.433
2017 Medina A, Parween S, Ullsten S, Vishnu N, Siu YT, Quach M, Bennet H, Balhuizen A, Åkesson L, Wierup N, Carlsson PO, Ahlgren U, Lernmark Å, Fex M. Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats. Diabetologia. PMID 29209740 DOI: 10.1007/S00125-017-4512-Z  0.484
2017 Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, et al. Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study. Diabetologia. PMID 29080005 DOI: 10.1007/S00125-017-4487-9  0.347
2017 Odermarsky M, Pesonen E, Sorsa T, Lernmark Å, Pussinen PJ, Liuba P. HLA, infections and inflammation in early stages of atherosclerosis in children with type 1 diabetes. Acta Diabetologica. PMID 29064046 DOI: 10.1007/S00592-017-1063-1  0.44
2017 Hagopian W, Lee HS, Liu E, Rewers M, She JX, Ziegler AG, Lernmark Å, Toppari J, Rich SS, Krischer JP, Erlich H, Akolkar B, Agardh D. Co-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity. Pediatrics. PMID 29018046 DOI: 10.1542/Peds.2017-1305  0.469
2017 Elding Larsson H, Lynch KF, Lönnrot M, Haller MJ, Lernmark Å, Hagopian WA, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Rewers MJ, Hyöty H. Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children. Diabetologia. PMID 28990147 DOI: 10.1007/S00125-017-4448-3  0.366
2017 Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M. Erratum to: Understanding and preventing type 1 diabetes through the unique working model of TrialNet. Diabetologia. PMID 28948305 DOI: 10.1007/S00125-017-4446-5  0.451
2017 Lynch KF, Lee HS, Törn C, Vehik K, Krischer JP, Larsson HE, Haller MJ, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Hyöty H, et al. Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies. Journal of Autoimmunity. PMID 28941965 DOI: 10.1016/J.Jaut.2017.09.005  0.391
2017 Krischer JP, Liu X, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report. Diabetes. PMID 28903990 DOI: 10.2337/Db17-0261  0.446
2017 Köhler M, Beyerlein A, Vehik K, Greven S, Umlauf N, Lernmark Å, Hagopian WA, Rewers M, She JX, Toppari J, Akolkar B, Krischer JP, Bonifacio E, Ziegler AG. Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study. Acta Diabetologica. PMID 28856522 DOI: 10.1007/S00592-017-1033-7  0.446
2017 Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M. Understanding and preventing type 1 diabetes through the unique working model of TrialNet. Diabetologia. PMID 28770323 DOI: 10.1007/S00125-017-4384-2  0.425
2017 Lönnrot M, Lynch KF, Elding Larsson H, Lernmark Å, Rewers MJ, Törn C, Burkhardt BR, Briese T, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Krischer JP, et al. Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study. Diabetologia. PMID 28770319 DOI: 10.1007/S00125-017-4365-5  0.436
2017 Zhao LP, Carlsson A, Elding Larsson H, Forsander G, Ivarsson SA, Kockum I, Ludvigsson J, Marcus C, Persson M, Samuelsson U, Örtqvist E, Pyo CW, Bolouri H, Zhao M, Nelson WC, et al. Building and Validating a Prediction model for Pediatric Type 1 Diabetes Risk Using Next Generation Targeted Sequencing of Class II HLA Genes. Diabetes/Metabolism Research and Reviews. PMID 28755385 DOI: 10.1002/Dmrr.2921  0.425
2017 Krischer JP, Lynch KF, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Toppari J, Ziegler AG, Akolkar B. Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study. Diabetes Care. PMID 28646072 DOI: 10.2337/Dc17-0238  0.448
2017 Regnell SE, Lernmark Å. Early prediction of autoimmune (type 1) diabetes. Diabetologia. PMID 28550517 DOI: 10.1007/S00125-017-4308-1  0.532
2017 Lundgren M, Steed LJ, Tamura R, Jonsdottir B, Gesualdo P, Crouch C, Sjöberg M, Hansson G, Hagopian WA, Ziegler AG, Rewers MJ, Lernmark Å, Toppari J, She JX, Akolkar B, et al. Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity. Bmc Pediatrics. 17: 127. PMID 28511706 DOI: 10.1186/S12887-017-0884-Y  0.364
2017 Jonsdottir B, Larsson C, Carlsson A, Forsander G, Ivarsson SA, Lernmark Å, Ludvigsson J, Marcus C, Samuelsson U, Örtqvist E, Larsson HE. Thyroid and Islet Autoantibodies Predict Autoimmune Thyroid Disease at Type 1 Diabetes Diagnosis. The Journal of Clinical Endocrinology and Metabolism. 102: 1277-1285. PMID 28388722 DOI: 10.1210/Jc.2016-2335  0.431
2017 Katsarou A, Gudbjörnsdottir S, Rawshani A, Dabelea D, Bonifacio E, Anderson BJ, Jacobsen LM, Schatz DA, Lernmark Å. Type 1 diabetes mellitus. Nature Reviews. Disease Primers. 3: 17016. PMID 28358037 DOI: 10.1038/nrdp.2017.16  0.386
2017 Yang J, Tamura RN, Aronsson CA, Uusitalo UM, Lernmark Å, Rewers M, Hagopian WA, She JX, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Norris JM, Virtanen SM, Agardh D, et al. Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study. The British Journal of Nutrition. 1-7. PMID 28249640 DOI: 10.1017/S0007114517000332  0.307
2017 Regnell SE, Hessner MJ, Jia S, Åkesson L, Stenlund H, Moritz T, La Torre D, Lernmark Å. Longitudinal analysis of hepatic transcriptome and serum metabolome demonstrates altered lipid metabolism following the onset of hyperglycemia in spontaneously diabetic biobreeding rats. Plos One. 12: e0171372. PMID 28192442 DOI: 10.1371/Journal.Pone.0171372  0.459
2017 Steck AK, Larsson HE, Liu X, Veijola R, Toppari J, Hagopian WA, Haller MJ, Ahmed S, Akolkar B, Lernmark Å, Rewers MJ, Krischer JP. Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls. Pediatric Diabetes. PMID 28127835 DOI: 10.1111/Pedi.12485  0.456
2017 Hummel S, Beyerlein A, Tamura R, Uusitalo U, Aronsson CA, Yang J, Riikonen A, Lernmark Å, Rewers MJ, Hagopian WA, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, et al. First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Diabetes Care. PMID 28096222 DOI: 10.2337/Dc16-1624  0.416
2016 Wester A, Skärstrand H, Lind A, Ramelius A, Carlsson A, Cedervall E, Jönsson B, Ivarsson SA, Larsson HE, Larsson K, Lindberg B, Neiderud J, Fex M, Törn C, Lernmark Å. An Increased Diagnostic Sensitivity of Truncated GAD65 Autoantibodies in Type 1 Diabetes may be Related to HLA-DQ8. Diabetes. PMID 28028075 DOI: 10.2337/Db16-0891  0.492
2016 Paul DS, Teschendorff AE, Dang MA, Lowe R, Hawa MI, Ecker S, Beyan H, Cunningham S, Fouts AR, Ramelius A, Burden F, Farrow S, Rowlston S, Rehnstrom K, Frontini M, et al. Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Nature Communications. 7: 13555. PMID 27898055 DOI: 10.1038/Ncomms13555  0.43
2016 Lernmark Å. Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy. Pediatric Diabetes. 17: 65-72. PMID 27411439 DOI: 10.1111/Pedi.12390  0.439
2016 Radenkovic M, Silver C, Arvastsson J, Lynch K, Lernmark Å, Harris RA, Agardh CD, Cilio CM. Altered regulatory T-cell phenotype in latent autoimmune diabetes of the adults (LADA). Clinical and Experimental Immunology. PMID 27357431 DOI: 10.1111/Cei.12834  0.416
2016 Vehik K, Lynch KF, Schatz DA, Akolkar B, Hagopian W, Rewers M, She JX, Simell O, Toppari J, Ziegler AG, Lernmark Å, Bonifacio E, Krischer JP. Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study. Diabetes Care. PMID 27311490 DOI: 10.2337/Dc16-0181  0.486
2016 Törn C, Liu X, Hagopian W, Lernmark Å, Simell O, Rewers M, Ziegler AG, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, Rich SS, et al. Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study. Scientific Reports. 6: 27887. PMID 27306948 DOI: 10.1038/Srep27887  0.415
2016 Pociot F, Lernmark Å. Genetic risk factors for type 1 diabetes. Lancet (London, England). 387: 2331-9. PMID 27302272 DOI: 10.1016/S0140-6736(16)30582-7  0.476
2016 Warvsten A, Björnfors M, Arvidsson M, Vaziri-Sani F, Jönsson I, Olsson GE, Ahlm C, Elding Larsson H, Lernmark Å, Nilsson AL. Islet autoantibodies present in association with Ljungan virus infection in bank voles (Myodes glareolus) in northern Sweden. Journal of Medical Virology. PMID 27283793 DOI: 10.1002/Jmv.24597  0.325
2016 Zhao LP, Bolouri H, Zhao M, Geraghty DE, Lernmark Å. An Object-Oriented Regression for Building Disease Predictive Models with Multiallelic HLA Genes. Genetic Epidemiology. 40: 315-32. PMID 27080919 DOI: 10.1002/Gepi.21968  0.327
2016 Sharma A, Liu X, Hadley D, Hagopian W, Liu E, Chen WM, Onengut-Gumuscu S, Simell V, Rewers M, Ziegler AG, Lernmark Å, Simell O, Toppari J, Krischer JP, Akolkar B, et al. Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort. Plos One. 11: e0152476. PMID 27015091 DOI: 10.1371/Journal.Pone.0152476  0.339
2016 Regnéll SE, Peterson P, Trinh L, Broberg P, Leander P, Lernmark Å, Månsson S, Larsson HE. Pancreas volume and fat fraction in children with Type 1 diabetes. Diabetic Medicine. 33: 1374-1379. PMID 26996278 DOI: 10.1111/Dme.13115  0.494
2016 Larsson HE, Vehik K, Haller MJ, Liu X, Akolkar B, Hagopian W, Krischer J, Lernmark Å, She JX, Simell O, Toppari J, Ziegler AG, Rewers M. Growth and risk for islet autoimmunity and progression to type 1 diabetes in early childhood: The Environmental Determinants of Diabetes in the Young Study. Diabetes. PMID 26993064 DOI: 10.2337/Db15-1180  0.477
2016 Zhao LP, Alshiekh S, Carlsson A, Elding-Larsson H, Forsander G, Ivarsson SA, Ludvigsson J, Kockum I, Marcus C, Persson M, Samuelsson U, Örtqvist E, Pyo CW, Nelson WC, Geraghty DE, et al. Next generation sequencing reveals that HLA-DRB3, -DRB4 and -DRB5 may be associated with islet autoantibodies and risk for childhood type 1 diabetes. Diabetes. PMID 26740600 DOI: 10.2337/Db15-1115  0.501
2015 Uusitalo U, Liu X, Yang J, Aronsson CA, Hummel S, Butterworth M, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Toppari J, Ziegler AG, Akolkar B, Krischer J, et al. Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study. Jama Pediatrics. 1-9. PMID 26552054 DOI: 10.1001/Jamapediatrics.2015.2757  0.436
2015 Maziarz M, Hagopian W, Palmer JP, Sanjeevi CB, Kockum I, Breslow N, Lernmark Å. Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies. Genes and Immunity. PMID 26513234 DOI: 10.1038/Gene.2015.43  0.473
2015 Leslie RD, Palmer J, Schloot NC, Lernmark A. Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment. Diabetologia. PMID 26498592 DOI: 10.1007/S00125-015-3789-Z  0.514
2015 Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, Greenbaum CJ, Herold KC, Krischer JP, Lernmark Å, Ratner RE, Rewers MJ, Schatz DA, Skyler JS, Sosenko JM, et al. Staging Presymptomatic Type 1 Diabetes: A Scientific Statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care. 38: 1964-74. PMID 26404926 DOI: 10.2337/Dc15-1419  0.443
2015 Gu Urban GJ, Friedman M, Ren P, Törn C, Fex M, Hampe CS, Lernmark Å, Landegren U, Kamali-Moghaddam M. Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome. Scientific Reports. 5: 11196. PMID 26080009 DOI: 10.1038/Srep11196  0.32
2015 Kanatsuna N, Delli A, Andersson C, Nilsson AL, Vaziri-Sani F, Larsson K, Carlsson A, Cedervall E, Jönsson B, Neiderud J, Elding Larsson H, Ivarsson SA, Törn C, Fex M, Lernmark Å. Doubly reactive INS-IGF2 autoantibodies in children with newly diagnosed autoimmune (type 1) diabetes. Scandinavian Journal of Immunology. PMID 26073034 DOI: 10.1111/Sji.12325  0.474
2015 Regnell SE, Peterson P, Trinh L, Broberg P, Leander P, Lernmark Å, Månsson S, Elding Larsson H. Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls. Metabolism: Clinical and Experimental. 64: 872-8. PMID 25982699 DOI: 10.1016/J.Metabol.2015.04.002  0.408
2015 Lönnrot M, Lynch K, Larsson HE, Lernmark Å, Rewers M, Hagopian W, She JX, Simell O, Ziegler AG, Akolkar B, Krischer J, Hyöty H. A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY. Bmc Pediatrics. 15: 24. PMID 25884839 DOI: 10.1186/S12887-015-0333-8  0.343
2015 Nilsson AL, Vaziri-Sani F, Broberg P, Elfaitouri A, Pipkorn R, Blomberg J, Ivarsson SA, Elding Larsson H, Lernmark Å. Serological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children. Journal of Medical Virology. 87: 1130-40. PMID 25873230 DOI: 10.1002/Jmv.24127  0.427
2015 Ling Z, De Pauw P, Jacobs-Tulleneers-Thevissen D, Mao R, Gillard P, Hampe CS, Martens GA, In't Veld P, Lernmark Å, Keymeulen B, Gorus F, Pipeleers D. Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients. The Journal of Clinical Endocrinology and Metabolism. 100: 2314-21. PMID 25816051 DOI: 10.1210/Jc.2015-1216  0.403
2015 Lernmark Å. The streetlight effect--is there light at the end of the tunnel? Diabetes. 64: 1105-7. PMID 25805764 DOI: 10.2337/Db15-0011  0.516
2015 Steck AK, Vehik K, Bonifacio E, Lernmark A, Ziegler AG, Hagopian WA, She J, Simell O, Akolkar B, Krischer J, Schatz D, Rewers MJ. Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care. 38: 808-13. PMID 25665818 DOI: 10.2337/Dc14-2426  0.502
2015 Krischer JP, Lynch KF, Schatz DA, Ilonen J, Lernmark Å, Hagopian WA, Rewers MJ, She JX, Simell OG, Toppari J, Ziegler AG, Akolkar B, Bonifacio E. The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study. Diabetologia. 58: 980-7. PMID 25660258 DOI: 10.1007/S00125-015-3514-Y  0.503
2015 Kemppainen KM, Ardissone AN, Davis-Richardson AG, Fagen JR, Gano KA, León-Novelo LG, Vehik K, Casella G, Simell O, Ziegler AG, Rewers MJ, Lernmark Å, Hagopian W, She JX, Krischer JP, et al. Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care. 38: 329-32. PMID 25519450 DOI: 10.2337/Dc14-0850  0.479
2015 Sarmiento J, Wallis RH, Ning T, Marandi L, Chao G, Veillette A, Lernmark Å, Paterson AD, Poussier P. A functional polymorphism of Ptpn22 is associated with type 1 diabetes in the BioBreeding rat. Journal of Immunology (Baltimore, Md. : 1950). 194: 615-29. PMID 25505293 DOI: 10.4049/Jimmunol.1302689  0.416
2015 Miyadera H, Ohashi J, Lernmark Å, Kitamura T, Tokunaga K. Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA. The Journal of Clinical Investigation. 125: 275-91. PMID 25485681 DOI: 10.1172/Jci74961  0.367
2015 Törn C, Hadley D, Lee HS, Hagopian W, Lernmark Å, Simell O, Rewers M, Ziegler A, Schatz D, Akolkar B, Onengut-Gumuscu S, Chen WM, Toppari J, Mykkänen J, Ilonen J, et al. Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study. Diabetes. 64: 1818-29. PMID 25422107 DOI: 10.2337/Db14-1497  0.415
2015 Elding Larsson H, Larsson C, Lernmark Å. Baseline heterogeneity in glucose metabolism marks the risk for type 1 diabetes and complicates secondary prevention. Acta Diabetologica. 52: 473-81. PMID 25381193 DOI: 10.1007/S00592-014-0680-1  0.486
2015 Skärstrand H, Vaziri-Sani F, Delli AJ, Törn C, Elding Larsson H, Ivarsson S, Agardh D, Lernmark Å. Neuropeptide Y is a minor autoantigen in newly diagnosed type 1 diabetes patients. Pediatric Diabetes. 16: 621-8. PMID 25258030 DOI: 10.1111/Pedi.12222  0.494
2015 Skärstrand H, Krupinska E, Haataja TJK, Vaziri-Sani F, Lagerstedt JO, Lernmark Å. Zinc transporter 8 (ZnT8) autoantibody epitope specificity and affinity examined with recombinant ZnT8 variant proteins in specific ZnT8R and ZnT8W autoantibody-positive type 1 diabetes patients Clinical and Experimental Immunology. 179: 220-229. PMID 25178386 DOI: 10.1111/Cei.12448  0.386
2014 Ahlgren KM, Fall T, Landegren N, Grimelius L, von Euler H, Sundberg K, Lindblad-Toh K, Lobell A, Hedhammar Å, Andersson G, Hansson-Hamlin H, Lernmark Å, Kämpe O. Lack of evidence for a role of islet autoimmunity in the aetiology of canine diabetes mellitus. Plos One. 9: e105473. PMID 25153886 DOI: 10.1371/Journal.Pone.0105473  0.494
2014 Adlercreutz EH, Svensson J, Hansen D, Buschard K, Lernmark A, Mortensen HB, Agardh D. Prevalence of celiac disease autoimmunity in children with type 1 diabetes: regional variations across the Øresund strait between Denmark and southernmost Sweden. Pediatric Diabetes. PMID 25131687 DOI: 10.1111/Pedi.12200  0.444
2014 Flanagan SE, Haapaniemi E, Russell MA, Caswell R, Lango Allen H, De Franco E, McDonald TJ, Rajala H, Ramelius A, Barton J, Heiskanen K, Heiskanen-Kosma T, Kajosaari M, Murphy NP, Milenkovic T, et al. Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease. Nature Genetics. 46: 812-4. PMID 25038750 DOI: 10.1038/Ng.3040  0.309
2014 Lundgren M, Sahlin Å, Svensson C, Carlsson A, Cedervall E, Jönsson B, Jönsson I, Larsson K, Lernmark Å, Neiderud J, Vigård T, Elding Larsson H. Reduced morbidity at diagnosis and improved glycemic control in children previously enrolled in DiPiS follow-up. Pediatric Diabetes. 15: 494-501. PMID 24823816 DOI: 10.1111/Pedi.12151  0.403
2014 Yang J, Lernmark Å, Uusitalo UM, Lynch KF, Veijola R, Winkler C, Larsson HE, Rewers M, She JX, Ziegler AG, Simell OG, Hagopian WA, Akolkar B, Krischer JP, Vehik K, et al. Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes. International Journal of Obesity (2005). 38: 1491-6. PMID 24694666 DOI: 10.1038/Ijo.2014.55  0.445
2014 Paulsson JF, Ludvigsson J, Carlsson A, Casas R, Forsander G, Ivarsson SA, Kockum I, Lernmark Å, Marcus C, Lindblad B, Westermark GT. High plasma levels of islet amyloid polypeptide in young with new-onset of type 1 diabetes mellitus. Plos One. 9: e93053. PMID 24671002 DOI: 10.1371/Journal.Pone.0093053  0.464
2014 Krause S, Landherr U, Agardh CD, Hausmann S, Link K, Hansen JM, Lynch KF, Powell M, Furmaniak J, Rees-Smith B, Bonifacio E, Ziegler AG, Lernmark A, Achenbach P. GAD autoantibody affinity in adult patients with latent autoimmune diabetes, the study participants of a GAD65 vaccination trial. Diabetes Care. 37: 1675-80. PMID 24598244 DOI: 10.2337/Dc13-1719  0.43
2014 Gyllenberg A, Piehl F, Alfredsson L, Hillert J, Bomfim IL, Padyukov L, Orho-Melander M, Lindholm E, Landin-Olsson M, Lernmark A, Olsson T, Kockum I. Variability in the CIITA gene interacts with HLA in multiple sclerosis Genes and Immunity. 15: 162-167. PMID 24430172 DOI: 10.1038/Gene.2013.71  0.446
2014 Lee HS, Burkhardt BR, Mcleod W, Smith S, Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP, et al. Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study Diabetes/Metabolism Research and Reviews. 30: 424-434. PMID 24339168 DOI: 10.1002/Dmrr.2510  0.487
2014 Svensson M, Ramelius A, Nilsson AL, Delli AJ, Elding Larsson H, Carlsson A, Forsander G, Ivarsson SA, Ludvigsson J, Kockum I, Marcus C, Samuelsson U, Örtqvist E, Lernmark Å. Antibodies to influenza virus A/H1N1 hemagglutinin in Type 1 diabetes children diagnosed before, during and after the SWEDISH A(H1N1)pdm09 vaccination campaign 2009-2010. Scandinavian Journal of Immunology. 79: 137-48. PMID 24313339 DOI: 10.1111/Sji.12138  0.32
2014 Andersson C, Kolmodin M, Ivarsson SA, Carlsson A, Forsander G, Lindblad B, Ludvigsson J, Kockum I, Marcus C, Samuelsson U, Ortqvist E, Lernmark A, Elding Larsson H, Törn C. Islet cell antibodies (ICA) identify autoimmunity in children with new onset diabetes mellitus negative for other islet cell antibodies. Pediatric Diabetes. 15: 336-44. PMID 24206368 DOI: 10.1111/Pedi.12093  0.486
2014 Elding Larsson H, Vehik K, Gesualdo P, Akolkar B, Hagopian W, Krischer J, Lernmark Å, Rewers M, Simell O, She JX, Ziegler A, Haller MJ. Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease. Pediatric Diabetes. 15: 118-26. PMID 24034790 DOI: 10.1111/Pedi.12066  0.48
2013 Lernmark Å. Depleting T cells in newly diagnosed autoimmune (type 1) diabetes--are we getting anywhere? Diabetes. 62: 3669-70. PMID 24158996 DOI: 10.2337/Db13-1207  0.455
2013 Lernmark A. Is there evidence for post-translational modification of beta cell autoantigens in the aetiology and pathogenesis of type 1 diabetes? Diabetologia. PMID 24022707 DOI: 10.1007/S00125-013-3041-7  0.494
2013 Kanatsuna N, Taneera J, Vaziri-Sani F, Wierup N, Larsson HE, Delli A, Skärstrand H, Balhuizen A, Bennet H, Steiner DF, Törn C, Fex M, Lernmark Ã…. Autoimmunity against INS-IGF2 protein expressed in human pancreatic islets. The Journal of Biological Chemistry. 288: 29013-23. PMID 23935095 DOI: 10.1074/Jbc.M113.478222  0.481
2013 La Torre D, Seppänen-Laakso T, Larsson HE, Hyötyläinen T, Ivarsson SA, Lernmark A, Oresic M. Decreased cord-blood phospholipids in young age-at-onset type 1 diabetes. Diabetes. 62: 3951-6. PMID 23929934 DOI: 10.2337/Db13-0215  0.418
2013 Skärstrand H, Dahlin LB, Lernmark A, Vaziri-Sani F. Neuropeptide Y autoantibodies in patients with long-term type 1 and type 2 diabetes and neuropathy. Journal of Diabetes and Its Complications. 27: 609-17. PMID 23910631 DOI: 10.1016/J.Jdiacomp.2013.06.007  0.483
2013 Larsson HE, Jönsson I, Lernmark A, Ivarsson S, Radtke JR, Hampe CS. Decline in titers of anti-idiotypic antibodies specific to autoantibodies to GAD65 (GAD65Ab) precedes development of GAD65Ab and type 1 diabetes. Plos One. 8: e65173. PMID 23785410 DOI: 10.1371/Journal.Pone.0065173  0.37
2013 Nilsson AL, Vaziri-Sani F, Andersson C, Larsson K, Carlsson A, Cedervall E, Jönsson B, Neiderud J, Elding Larsson H, Ivarsson SA, Lernmark Å. Relationship between Ljungan virus antibodies, HLA-DQ8, and insulin autoantibodies in newly diagnosed type 1 diabetes children. Viral Immunology. 26: 207-15. PMID 23682738 DOI: 10.1089/Vim.2013.0008  0.427
2013 Vehik K, Fiske SW, Logan CA, Agardh D, Cilio CM, Hagopian W, Simell O, Roivainen M, She JX, Briese T, Oikarinen S, Hyoty H, Ziegler AG, Rewers M, Lernmark A, et al. Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY. Diabetes/Metabolism Research and Reviews. 29: 557-67. PMID 23674484 DOI: 10.1002/Dmrr.2427  0.372
2013 Jonsdottir B, Andersson C, Carlsson A, Delli A, Forsander G, Ludvigsson J, Marcus C, Samuelsson U, Ortqvist E, Lernmark A, Ivarsson SA, Larsson HE. Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents. Diabetologia. 56: 1735-42. PMID 23666211 DOI: 10.1007/S00125-013-2934-9  0.454
2013 Lee HS, Briese T, Winkler C, Rewers M, Bonifacio E, Hyoty H, Pflueger M, Simell O, She JX, Hagopian W, Lernmark A, Akolkar B, Krischer JP, Ziegler AG. Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes. Diabetologia. 56: 1705-11. PMID 23657799 DOI: 10.1007/S00125-013-2924-Y  0.47
2013 Ludvigsson J, Carlsson A, Deli A, Forsander G, Ivarsson SA, Kockum I, Lindblad B, Marcus C, Lernmark Å, Samuelsson U. Decline of C-peptide during the first year after diagnosis of Type 1 diabetes in children and adolescents. Diabetes Research and Clinical Practice. 100: 203-9. PMID 23529064 DOI: 10.1016/J.Diabres.2013.03.003  0.341
2013 Andersson C, Carlsson A, Cilio C, Cedervall E, Ivarsson SA, Jonsdottir B, Jönsson B, Larsson K, Neiderud J, Lernmark A, Elding Larsson H. Glucose tolerance and beta-cell function in islet autoantibody-positive children recruited to a secondary prevention study. Pediatric Diabetes. 14: 341-9. PMID 23469940 DOI: 10.1111/Pedi.12023  0.356
2013 Galgani M, Nugnes R, Bruzzese D, Perna F, De Rosa V, Procaccini C, Mozzillo E, Cilio CM, Elding Larsson H, Lernmark A, La Cava A, Franzese A, Matarese G. Meta-immunological profiling of children with type 1 diabetes identifies new biomarkers to monitor disease progression. Diabetes. 62: 2481-91. PMID 23396400 DOI: 10.2337/Db12-1273  0.449
2013 Lernmark A, Larsson HE. Immune therapy in type 1 diabetes mellitus. Nature Reviews. Endocrinology. 9: 92-103. PMID 23296174 DOI: 10.1038/Nrendo.2012.237  0.45
2013 Regnéll SE, Lernmark Å. The environment and the origins of islet autoimmunity and Type 1 diabetes. Diabetic Medicine. 30: 155-160. PMID 23252770 DOI: 10.1111/Dme.12099  0.511
2013 Skärstrand H, Lernmark A, Vaziri-Sani F. Antigenicity and epitope specificity of ZnT8 autoantibodies in type 1 diabetes. Scandinavian Journal of Immunology. 77: 21-29. PMID 23126564 DOI: 10.1111/Sji.12008  0.384
2013 Bogdani M, Henschel AM, Kansra S, Fuller JM, Geoffrey R, Jia S, Kaldunski ML, Pavletich S, Prosser S, Chen YG, Lernmark A, Hessner MJ. Biobreeding rat islets exhibit reduced antioxidative defense and N-acetyl cysteine treatment delays type 1 diabetes. The Journal of Endocrinology. 216: 111-23. PMID 23111281 DOI: 10.1530/Joe-12-0385  0.394
2013 Samuelsson U, Lindblad B, Carlsson A, Forsander G, Ivarsson S, Kockum I, Lernmark Å, Marcus C, Ludvigsson J. Residual beta cell function at diagnosis of type 1 diabetes in children and adolescents varies with gender and season. Diabetes/Metabolism Research and Reviews. 29: 85-9. PMID 23081842 DOI: 10.1002/Dmrr.2365  0.413
2013 Andersson C, Vaziri-Sani F, Delli A, Lindblad B, Carlsson A, Forsander G, Ludvigsson J, Marcus C, Samuelsson U, Ivarsson S, Lernmark A, Larsson HE. Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes. Pediatric Diabetes. 14: 97-105. PMID 22957668 DOI: 10.1111/J.1399-5448.2012.00916.X  0.449
2013 Delli AJ, Lernmark Å. Autoimmune (type 1) diabetes Autoimmune Diseases. 575-585. DOI: 10.1016/B978-0-12-812102-3.00041-5  0.535
2012 Gyllenberg A, Asad S, Piehl F, Swanberg M, Padyukov L, Van Yserloo B, Rutledge EA, McNeney B, Graham J, Orho-Melander M, Lindholm E, Graff C, Forsell C, Akesson K, Landin-Olsson M, ... ... Lernmark A, et al. Age-dependent variation of genotypes in MHC II transactivator gene (CIITA) in controls and association to type 1 diabetes. Genes and Immunity. 13: 632-40. PMID 23052709 DOI: 10.1038/Gene.2012.44  0.366
2012 Delli AJ, Vaziri-Sani F, Lindblad B, Elding-Larsson H, Carlsson A, Forsander G, Ivarsson SA, Ludvigsson J, Kockum I, Marcus C, Samuelsson U, Örtqvist E, Groop L, Bondinas GP, Papadopoulos GK, et al. Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study. Diabetes. 61: 2556-64. PMID 22787139 DOI: 10.2337/Db11-1659  0.427
2012 Rešić Lindehammer S, Honkanen H, Nix WA, Oikarinen M, Lynch KF, Jönsson I, Marsal K, Oberste S, Hyöty H, Lernmark Å. Seroconversion to islet autoantibodies after enterovirus infection in early pregnancy. Viral Immunology. 25: 254-61. PMID 22746839 DOI: 10.1089/Vim.2012.0022  0.425
2012 Andersen ML, Vaziri-Sani F, Delli A, Pörksen S, Jacobssen E, Thomsen J, Svensson J, Steen Petersen J, Hansen L, Lernmark A, Mortensen HB, Nielsen LB. Association between autoantibodies to the Arginine variant of the Zinc transporter 8 (ZnT8) and stimulated C-peptide levels in Danish children and adolescents with newly diagnosed type 1 diabetes. Pediatric Diabetes. 13: 454-62. PMID 22686132 DOI: 10.1111/J.1399-5448.2012.00857.X  0.355
2012 Asad S, Nikamo P, Gyllenberg A, Bennet H, Hansson O, Wierup N, Carlsson A, Forsander G, Ivarsson SA, Larsson H, Lernmark Å, Lindblad B, Ludvigsson J, Marcus C, et al. HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. Plos One. 7: e35439. PMID 22563461 DOI: 10.1371/Journal.Pone.0035439  0.364
2012 Sorensen JS, Vaziri-Sani F, Maziarz M, Kristensen K, Ellerman A, Breslow N, Lernmark A, Pociot F, Brorsson C, Birkebaek NH. Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years Diabetes Research and Clinical Practice. 96: 204-210. PMID 22251574 DOI: 10.1016/J.Diabres.2011.12.013  0.365
2012 Papadopoulou A, Lynch KF, Anderberg E, Landin-Olsson M, Hansson I, Agardh CD, Lernmark Å, Berntorp K. HLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus. Diabetes Research and Clinical Practice. 95: 260-4. PMID 22104260 DOI: 10.1016/J.Diabres.2011.10.037  0.514
2012 Svensson J, Eising S, Mortensen HB, Christiansen M, Laursen I, Lernmark Å, Nilsson A, Simonsen LB, Carstensen B, Pociot F, Johannesen J. High levels of immunoglobulin E and a continuous increase in immunoglobulin G and immunoglobulin M by age in children with newly diagnosed type 1 diabetes. Human Immunology. 73: 17-25. PMID 22057035 DOI: 10.1016/J.Humimm.2011.10.019  0.444
2012 Ludvigsson J, Carlsson A, Forsander G, Ivarsson S, Kockum I, Lernmark A, Lindblad B, Marcus C, Samuelsson U. C-peptide in the classification of diabetes in children and adolescents. Pediatric Diabetes. 13: 45-50. PMID 21910810 DOI: 10.1111/J.1399-5448.2011.00807.X  0.439
2012 Carlsson A, Kockum I, Lindblad B, Engleson L, Nilsson A, Forsander G, Karlsson AK, Kernell A, Ludvigsson J, Marcus C, Zachrisson I, Ivarsson SA, Lernmark A. Low risk HLA-DQ and increased body mass index in newly diagnosed type 1 diabetes children in the Better Diabetes Diagnosis study in Sweden. International Journal of Obesity (2005). 36: 718-24. PMID 21712811 DOI: 10.1038/Ijo.2011.122  0.446
2011 Regnell SE, Lernmark Å. Hepatic steatosis in type 1 diabetes. The Review of Diabetic Studies : Rds. 8: 454-67. PMID 22580727 DOI: 10.1900/RDS.2011.8.454  0.322
2011 Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A. BB rat Gimap gene expression in sorted lymphoid T and B cells. Life Sciences. 89: 748-54. PMID 21925515 DOI: 10.1016/J.Lfs.2011.08.016  0.331
2011 Lindehammer SR, Fex M, Maziarz M, Hanson I, Maršál K, Lernmark A. Early-pregnancy cytokines in mothers to children developing multiple, persistent islet autoantibodies, type 1 diabetes, or both before 7 years of age. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 66: 495-503. PMID 21819478 DOI: 10.1111/J.1600-0897.2011.01057.X  0.438
2011 Vaziri-Sani F, Delli AJ, Elding-Larsson H, Lindblad B, Carlsson A, Forsander G, Ivarsson SA, Ludvigsson J, Marcus C, Lernmark Å. A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes. Journal of Immunological Methods. 371: 25-37. PMID 21708156 DOI: 10.1016/J.Jim.2011.06.011  0.483
2011 Papadopoulou A, Lynch K, Shaat N, Håkansson R, Ivarsson S, Berntorp K, Agardh C, Lernmark Å. Gestational diabetes mellitus is associated with TCF7L2 gene polymorphisms independent of HLA-DQB1*0602 genotypes and islet cell autoantibodies Diabetic Medicine. 28: 1018-1027. PMID 21672010 DOI: 10.1111/J.1464-5491.2011.03359.X  0.492
2011 Lernmark Ã…, Larsson HE. Editorial Comment on type 1 diabetes and antigen-specific immunotherapy. Journal of Internal Medicine. 270: 132-5. PMID 21668820 DOI: 10.1111/J.1365-2796.2011.02412.X  0.497
2011 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM. Executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clinical Chemistry. 57: 793-8. PMID 21617153 DOI: 10.1373/Clinchem.2011.163634  0.424
2011 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clinical Chemistry. 57: e1-e47. PMID 21617152 DOI: 10.1373/Clinchem.2010.161596  0.308
2011 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM. Position statement executive summary: guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care. 34: 1419-23. PMID 21617111 DOI: 10.2337/Dc11-9997  0.426
2011 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Diabetes Care. 34: e61-99. PMID 21617108 DOI: 10.2337/Dc11-9998  0.422
2011 Nielsen LB, Vaziri-Sani F, Pörksen S, Andersen ML, Svensson J, Bergholdt R, Pociot F, Hougaard P, de Beaufort C, Castaño L, Mortensen HB, Lernmark A, Hansen L. Relationship between ZnT8Ab, the SLC30A8 gene and disease progression in children with newly diagnosed type 1 diabetes. Autoimmunity. 44: 616-23. PMID 21604969 DOI: 10.3109/08916934.2011.576724  0.477
2011 Hagopian WA, Erlich H, Lernmark A, Rewers M, Ziegler AG, Simell O, Akolkar B, Vogt R, Blair A, Ilonen J, Krischer J, She J. The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants. Pediatric Diabetes. 12: 733-43. PMID 21564455 DOI: 10.1111/J.1399-5448.2011.00774.X  0.454
2011 Sterner Y, Törn C, Lee HS, Larsson H, Winkler C, McLeod W, Lynch K, Simell O, Ziegler A, Schatz D, Hagopian W, Rewers M, She JX, Krischer JP, Akolkar B, ... Lernmark A, et al. Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics. Journal of Perinatology : Official Journal of the California Perinatal Association. 31: 764-9. PMID 21527903 DOI: 10.1038/Jp.2011.26  0.426
2011 Larsson HE, Lernmark Ã…. Vaccination against type 1 diabetes. Journal of Internal Medicine. 269: 626-35. PMID 21481019 DOI: 10.1111/J.1365-2796.2011.02386.X  0.502
2011 Jensen RA, Agardh E, Lernmark A, Gudbjörnsdottir S, Smith NL, Siscovick DS, Törn C. HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later. Plos One. 6: e17569. PMID 21412422 DOI: 10.1371/Journal.Pone.0017569  0.509
2011 Larsson HE, Lernmark A. Does immune-tolerance treatment with Alum-formulated GAD65 protect insulin-production in the pancreatic islet β cells? Human Vaccines. 7: 45-9. PMID 21263221 DOI: 10.4161/Hv.7.1.14488  0.534
2011 Andersson C, Larsson K, Vaziri-Sani F, Lynch K, Carlsson A, Cedervall E, Jönsson B, Neiderud J, Månsson M, Nilsson A, Lernmark A, Elding Larsson H, Ivarsson SA. The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes. Autoimmunity. 44: 394-405. PMID 21244337 DOI: 10.3109/08916934.2010.540604  0.46
2011 Moralejo D, Yanay O, Kernan K, Bailey A, Lernmark A, Osborne W. Sustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats. Journal of Bioscience and Bioengineering. 111: 383-7. PMID 21216666 DOI: 10.1016/J.Jbiosc.2010.12.008  0.473
2011 Mendu SK, Åkesson L, Jin Z, Edlund A, Cilio C, Lernmark A, Birnir B. Increased GABAA channel subunits expression in CD8+ but not in CD4+ T cells in BB rats developing diabetes compared to their congenic littermates Molecular Immunology. 48: 399-407. PMID 21112637 DOI: 10.1016/J.Molimm.2010.08.005  0.307
2011 Lindehammer SR, Hansson I, Midberg B, Ivarsson SA, Lynch KF, Dillner J, Lernmark A. Seroconversion to islet autoantibodies between early pregnancy and delivery in non-diabetic mothers. Journal of Reproductive Immunology. 88: 72-9. PMID 21111487 DOI: 10.1016/J.Jri.2010.10.002  0.452
2011 Eising S, Nilsson A, Carstensen B, Hougaard DM, Nørgaard-Pedersen B, Nerup J, Lernmark A, Pociot F. Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes. European Journal of Endocrinology / European Federation of Endocrine Societies. 164: 247-52. PMID 21097569 DOI: 10.1530/Eje-10-0792  0.465
2011 Brorsson C, Vaziri-Sani F, Bergholdt R, Eising S, Nilsson A, Svensson J, Lernmark Å, Pociot F. Correlations between islet autoantibody specificity and the SLC30A8 genotype with HLA-DQB1 and metabolic control in new onset type 1 diabetes. Autoimmunity. 44: 107-14. PMID 20836749 DOI: 10.3109/08916934.2010.509120  0.461
2011 Hansson I, Lynch KF, Hallmans G, Lernmark Å, Rolandsson O. High-titer GAD65 autoantibodies detected in adult diabetes patients using a high efficiency expression vector and cold GAD65 displacement. Autoimmunity. 44: 129-36. PMID 20670115 DOI: 10.3109/08916934.2010.482117  0.447
2011 Sacks DB, Arnold M, Bakris GL, Bruns DE, Horvath AR, Kirkman MS, Lernmark A, Metzger BE, Nathan DM. Translation: Executive Summary: Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus. Laboratory Medicine Online. 1: 173-178. DOI: 10.3343/Lmo.2011.1.4.1  0.416
2011 Åkesson L, Trygg J, Fuller JM, Madsen R, Gabrielsson J, Bruce S, Stenlund H, Tupling T, Pefley R, Lundstedt T, Lernmark A, Moritz T. Serum metabolite signature predicts the acute onset of diabetes in spontaneously diabetic congenic BB rats Metabolomics. 7: 593-603. DOI: 10.1007/S11306-011-0278-3  0.479
2010 Örtqvist E, Brooks-Worrell B, Lynch K, Radtke J, Bekris LM, Kockum I, Agardh CD, Cilio CM, Lethagen AL, Persson B, Lernmark A, Reichow J, Oak S, Palmer JP, Hampe CS. Changes in GAD65Ab-specific antiidiotypic antibody levels correlate with changes in C-peptide levels and progression to islet cell autoimmunity Journal of Clinical Endocrinology and Metabolism. 95. PMID 20685858 DOI: 10.1210/Jc.2010-0785  0.402
2010 Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat. Diabetes. 59: 2375-85. PMID 20682698 DOI: 10.2337/Db10-0372  0.476
2010 Yanay O, Moralejo D, Kernan K, Brzezinski M, Fuller JM, Barton RW, Lernmark A, Osborne WR. Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide Journal of Gene Medicine. 12: 538-544. PMID 20527046 DOI: 10.1002/Jgm.1466  0.463
2010 Maziarz M, Janer M, Roach JC, Hagopian W, Palmer JP, Deutsch K, Sanjeevi CB, Kockum I, Breslow N, Lernmark A. The association between the PTPN22 1858CT variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies Genes and Immunity. 11: 406-415. PMID 20445565 DOI: 10.1038/Gene.2010.12  0.446
2010 Akesson C, Uvebrant K, Oderup C, Lynch K, Harris RA, Lernmark A, Agardh CD, Cilio CM. Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency. Clinical and Experimental Immunology. 161: 48-56. PMID 20408863 DOI: 10.1111/J.1365-2249.2010.04114.X  0.452
2010 Delli AJ, Lindblad B, Carlsson A, Forsander G, Ivarsson SA, Ludvigsson J, Marcus C, Lernmark A. Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies. Pediatric Diabetes. 11: 513-20. PMID 20337975 DOI: 10.1111/J.1399-5448.2010.00637.X  0.493
2010 Vaziri-Sani F, Oak S, Radtke J, Lernmark Å, Lynch K, Agardh C-, Cilio CM, Lethagen ÅL, Örtqvist E, Landin-Olsson M, Törn C, Hampe CS. ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset. Autoimmunity. 43: 598-606. PMID 20298127 DOI: 10.3109/08916930903555927  0.49
2010 La Torre D, Lernmark A. Immunology of beta-cell destruction. Advances in Experimental Medicine and Biology. 654: 537-83. PMID 20217514 DOI: 10.1007/978-90-481-3271-3_24  0.399
2010 Burbelo PD, Hirai H, Issa AT, Kingman A, Lernmark A, Ivarsson SA, Notkins AL, Iadarola MJ. Comparison of radioimmunoprecipitation with luciferase immunoprecipitation for autoantibodies to GAD65 and IA-2beta. Diabetes Care. 33: 754-6. PMID 20086252 DOI: 10.2337/Dc09-1938  0.445
2010 Moralejo DH, Hansen CT, Treuting P, Hessner MJ, Fuller JM, Van Yserloo B, Jensen R, Osborne W, Kwitek AE, Lernmark A. Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats. Physiological Genomics. 41: 9-20. PMID 19996157 DOI: 10.1152/Physiolgenomics.00186.2009  0.348
2010 Nilsson A, Lagerquist E, Lynch K, Lernmark Å, Rolandsson O. Temporal Variation of Ljungan Virus Antibody Levels in Relation to Islet Autoantibodies and Possible Correlation to Childhood Type 1 Diabetes The Open Pediatric Medicine Journal. 3: 61-66. DOI: 10.2174/1874309900903010061  0.42
2010 Örtqvist E, Brooks-Worrell B, Lynch K, Radtke J, Bekris LM, Kockum I, Agardh C, Cilio CM, Lethagen AL, Persson B, Lernmark A, Reichow J, Oak S, Palmer JP, Hampe CS. Changes in 65-Kilodalton Glutamate Decarboxylase Antibody-Specific Antiidiotypic Antibody Levels Correlate with Changes in C-Peptide Levels and Progression to Islet Cell Autoimmunity Endocrinology. 151: 4595-4595. DOI: 10.1210/Endo.151.9.9997  0.301
2009 Lynch KF, Subramanian SV, Ohlsson H, Chaix B, Lernmark A, Merlo J. Context and disease when disease risk is low: the case of type 1 diabetes in Sweden. Journal of Epidemiology and Community Health. 64: 789-95. PMID 19833608 DOI: 10.1136/Jech.2008.083667  0.418
2009 Oak S, Radtke J, Landin-Olsson M, Törn C, Lernmark A, Hampe CS. Comparison of three assays for the detection of GAD65Ab-specific anti-idiotypic antibodies. Journal of Immunological Methods. 351: 55-61. PMID 19781546 DOI: 10.1016/J.Jim.2009.09.004  0.359
2009 Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A. Sequence variation and expression of the Gimap gene family in the BB rat. Experimental Diabetes Research. 2009: 835650. PMID 19421422 DOI: 10.1155/2009/835650  0.381
2009 Agardh C, Lynch K, Palmér M, Link K, Lernmark Å. GAD65 vaccination: 5 years of follow-up in a randomised dose-escalating study in adult-onset autoimmune diabetes. Diabetologia. 52: 1363-1368. PMID 19404608 DOI: 10.1007/S00125-009-1371-2  0.339
2009 Fuller JM, Bogdani M, Tupling TD, Jensen RA, Pefley R, Manavi S, Cort L, Blankenhorn EP, Mordes JP, Lernmark A, Kwitek AE. Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene. Physiological Genomics. 38: 89-97. PMID 19351909 DOI: 10.1152/Physiolgenomics.00015.2009  0.377
2009 Papadopoulou A, Lynch K, Shaat N, Nilsson A, Lernmark B, Berntorp K, Ivarsson S, Agardh C, Lernmark Å. The type 1 diabetes protective HLA DQB1*0602 allele is less frequent in gestational diabetes mellitus Diabetologia. 52: 1339-1342. PMID 19347328 DOI: 10.1007/S00125-009-1351-6  0.468
2009 Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP. Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 20: 162-9. PMID 19205800 DOI: 10.1007/S00335-009-9172-Y  0.442
2009 Akesson K, Carlsson A, Ivarsson SA, Johansson C, Weidby BM, Ludvigsson J, Gustavsson B, Lernmark A, Kockum I. The non-inherited maternal HLA haplotype affects the risk for type 1 diabetes. International Journal of Immunogenetics. 36: 1-8. PMID 19055605 DOI: 10.1111/J.1744-313X.2008.00802.X  0.417
2008 Rewers M, She JX, Ziegler AG, Simell OG, Lernmark Å, Hagopian WA, Krischer JP, Akolkar B. The Environmental Determinants of Diabetes in the Young (TEDDY) Study Pediatric Diabetes. 8: 286-298. PMID 19120261 DOI: 10.1196/Annals.1447.062  0.475
2008 Uibo R, Lernmark A. GAD65 autoimmunity-clinical studies. Advances in Immunology. 100: 39-78. PMID 19111163 DOI: 10.1016/S0065-2776(08)00803-1  0.516
2008 Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, ... Lernmark A, et al. Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood. 112: 4905-14. PMID 18796632 DOI: 10.1182/Blood-2008-03-146555  0.312
2008 Larsson K, Carlsson A, Cederwall E, Jönsson B, Neiderud J, Jonsson B, Lernmark A, Ivarsson SA. Annual screening detects celiac disease in children with type 1 diabetes. Pediatric Diabetes. 9: 354-9. PMID 18774995 DOI: 10.1111/J.1399-5448.2008.00367.X  0.373
2008 Resic-Lindehammer S, Larsson K, Ortqvist E, Carlsson A, Cederwall E, Cilio CM, Ivarsson SA, Jönsson BA, Larsson HE, Lynch K, Neiderud J, Nilsson A, Sjöblad S, Lernmark A, et al. Temporal trends of HLA genotype frequencies of type 1 diabetes patients in Sweden from 1986 to 2005 suggest altered risk. Acta Diabetologica. 45: 231-5. PMID 18769865 DOI: 10.1007/S00592-008-0048-5  0.469
2008 Elfving M, Svensson J, Oikarinen S, Jonsson B, Olofsson P, Sundkvist G, Lindberg B, Lernmark A, Hyöty H, Ivarsson SA. Maternal enterovirus infection during pregnancy as a risk factor in offspring diagnosed with type 1 diabetes between 15 and 30 years of age. Experimental Diabetes Research. 2008: 271958. PMID 18670622 DOI: 10.1155/2008/271958  0.455
2008 Larsson HE, Hansson G, Carlsson A, Cederwall E, Jonsson B, Jönsson B, Larsson K, Lynch K, Neiderud J, Lernmark A, Ivarsson SA. Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes. Diabetologia. 51: 1623-30. PMID 18592208 DOI: 10.1007/S00125-008-1074-0  0.486
2008 Burbelo PD, Hirai H, Leahy H, Lernmark A, Ivarsson SA, Iadarola MJ, Notkins AL. A new luminescence assay for autoantibodies to mammalian cell-prepared insulinoma-associated protein 2. Diabetes Care. 31: 1824-6. PMID 18535195 DOI: 10.2337/Dc08-0286  0.349
2008 Akesson L, Gelling RW, Jensen R, Ogimoto K, Fuller JM, Pefley R, Manavi S, Lernmark A, Schwartz MW. Increased lipid oxidation heralds diabetes onset in DR.lyp/lyp rats. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 116: 475-80. PMID 18465680 DOI: 10.1055/S-2008-1062713  0.445
2008 Ivarsson SA, Lernmark A. Comment on: Edghill et al. (2008) Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood: Diabetes 57:1034-1042, 2008. Diabetes. 57: e9. PMID 18443369 DOI: 10.2337/Db08-0091  0.482
2008 Sweet IR, Yanay O, Waldron L, Gilbert M, Fuller JM, Tupling T, Lernmark A, Osborne WR. Treatment of diabetic rats with encapsulated islets. Journal of Cellular and Molecular Medicine. 12: 2644-50. PMID 18373735 DOI: 10.1111/J.1582-4934.2008.00322.X  0.428
2008 Hirai H, Miura J, Hu Y, Larsson H, Larsson K, Lernmark A, Ivarsson SA, Wu T, Kingman A, Tzioufas AG, Notkins AL. Selective screening of secretory vesicle-associated proteins for autoantigens in type 1 diabetes: VAMP2 and NPY are new minor autoantigens. Clinical Immunology (Orlando, Fla.). 127: 366-74. PMID 18359275 DOI: 10.1016/J.Clim.2008.01.018  0.463
2008 Odermarsky M, Lernmark A, Truedsson L, Liuba P. Cutaneous microvascular dysfunction is associated with human leukocyte antigen-DQ in youths with type 1 diabetes. Pediatric Research. 63: 420-2. PMID 18356750 DOI: 10.1203/Pdr.0B013E318165Bfd4  0.489
2008 Steed J, Gilliam LK, Harris RA, Lernmark A, Hampe CS. Antigen presentation of detergent-free glutamate decarboxylase (GAD65) is affected by human serum albumin as carrier protein. Journal of Immunological Methods. 334: 114-21. PMID 18353353 DOI: 10.1016/J.Jim.2008.02.006  0.353
2008 Nalini R, Gaur LK, Maldonado M, Hampe CS, Rodriguez L, Garza G, Lernmark A, Balasubramanyam A. HLA class II alleles specify phenotypes of ketosis-prone diabetes Diabetes Care. 31: 1195-1200. PMID 18316396 DOI: 10.2337/Dc07-1971  0.426
2008 Lynch KF, Lernmark B, Merlo J, Cilio CM, Ivarsson S, Lernmark Å. Cord blood islet autoantibodies and seasonal association with the type 1 diabetes high-risk genotype Journal of Perinatology. 28: 211-217. PMID 18273032 DOI: 10.1038/Sj.Jp.7211912  0.445
2008 Elfving M, Lindberg B, Lynch K, Månsson M, Sundkvist G, Lernmark A, Ivarsson SA. Number of islet autoantibodies present in newly diagnosed type 1 diabetes children born to non-diabetic mothers is affected by islet autoantibodies present at birth Pediatric Diabetes. 9: 127-134. PMID 18221435 DOI: 10.1111/J.1399-5448.2007.00349.X  0.496
2008 Sanjeevi CB, Hagopian WA, Landin-Olsson M, Kockum I, Woo W, Palmer JP, Lernmark A, Dahlquist G. Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DQ8 Tissue Antigens. 51: 281-286. PMID 9550329 DOI: 10.1111/J.1399-0039.1998.Tb03103.X  0.423
2008 Odermarsky M, Lernmark Å, Liuba P. Cutaneous microvascular dysfunction is associated with diabetes-risk HLA in youths with type 1 diabetes Journal of the American College of Cardiology. 51: 345-345. DOI: 10.1016/J.Jacc.2008.02.010  0.5
2008 Blankenhorn E, Cort L, b J, Lernmark Å, Mordes J. Sa.85. Gene Candidates for the Diabetes Susceptibility Locus Iddm14 Identified in Inbred and Recombinant Congenic Rats Clinical Immunology. 127: S108. DOI: 10.1016/J.Clim.2008.03.306  0.437
2007 Fawwaz S, Nikamo P, Törn C, Landin-Olsson M, Lernmark Å, Alarcon-Riquelme M, Kockum I. No evidence of association of the PDCD1 gene with Type 1 diabetes. Diabetic Medicine. 24: 1473-1477. PMID 18042085 DOI: 10.1111/J.1464-5491.2007.02297.X  0.316
2007 Elfving M, Lindberg B, Lynch K, Ivarsson SA, Lernmark A, Hampe CS. Epitope analysis of GAD65 binding in both cord blood and at the time of clinical diagnosis of childhood type 1 diabetes Hormone and Metabolic Research. 39: 790-796. PMID 17992632 DOI: 10.1055/S-2007-992128  0.326
2007 Eising S, Svensson J, Skogstrand K, Nilsson A, Lynch K, Andersen PS, Lernmark Å, Hougaard DM, Pociot F, Nørgaard-Pedersen B, Nerup J. Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case–control study Paediatric and Perinatal Epidemiology. 21: 507-517. PMID 17937736 DOI: 10.1111/J.1365-3016.2007.00846.X  0.393
2007 Odermarsky M, Nilsson A, Lernmark Å, Sjöblad S, Liuba P. Atherogenic vascular and lipid phenotypes in young patients with Type 1 diabetes are associated with diabetes high-risk HLA genotype. American Journal of Physiology-Heart and Circulatory Physiology. 293: 3175-3179. PMID 17906106 DOI: 10.1152/Ajpheart.00795.2007  0.485
2007 Krischer J, Rewers M, Barriga K, Baxter J, Deas A, Eisenbarth G, Emery L, Gesualdo P, Hoffman M, Norris J, Waugh K, Weber S, She JX, Muir A, Schatz D, ... ... Lernmark A, et al. The Environmental Determinants of Diabetes in the Young (TEDDY) study: Study design Pediatric Diabetes. 8: 286-298. PMID 17850472 DOI: 10.1111/J.1399-5448.2007.00269.X  0.476
2007 Jensen R, Gilliam L, Törn C, Landin-Olsson M, Palmer J, Akesson K, Kockum I, Lernmark B, Karlsson AF, Lynch K, Breslow N, Lernmark Å, Sundkvist G. Islet cell autoantibody levels after the diagnosis of young adult diabetic patients. Diabetic Medicine. 24: 1221-1228. PMID 17725633 DOI: 10.1111/J.1464-5491.2007.02235.X  0.415
2007 Akesson L, Hawkins T, Jensen R, Fuller JM, Breslow NE, Lernmark A. Decreased core temperature and increased beta(3)-adrenergic sensitivity in diabetes-prone BB rats. Diabetes Technology & Therapeutics. 9: 354-62. PMID 17705691 DOI: 10.1089/Dia.2006.0036  0.476
2007 Jonson CO, Lernmark A, Ludvigsson J, Rutledge EA, Hinkkanen A, Faresjö M. The importance of CTLA-4 polymorphism and human leukocyte antigen genotype for the induction of diabetes-associated cytokine response in healthy school children Pediatric Diabetes. 8: 185-192. PMID 17659059 DOI: 10.1111/J.1399-5448.2007.00245.X  0.44
2007 Shin JH, Janer M, McNeney B, Blay S, Deutsch K, Sanjeevi CB, Kockum I, Lernmark A, Graham J, Arnqvist H, Björck E, Eriksson J, Nyström L, et al. IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5. Genes and Immunity. 8: 503-12. PMID 17641683 DOI: 10.1038/Sj.Gene.6364413  0.51
2007 Jensen RA, Gilliam LK, Törn C, Landin-Olsson M, Karlsson FA, Palmer JP, Kockum I, Akesson K, Lernmark B, Lynch K, Breslow N, Lernmark A. Multiple factors affect the loss of measurable C-peptide over 6 years in newly diagnosed 15- to 35-year-old diabetic subjects. Journal of Diabetes and Its Complications. 21: 205-13. PMID 17616349 DOI: 10.1016/J.Jdiacomp.2006.01.004  0.38
2007 Thomson G, Valdes AM, Noble JA, Kockum I, Grote MN, Najman J, Erlich HA, Cucca F, Pugliese A, Steenkiste A, Dorman JS, Caillat-Zucman S, Hermann R, Ilonen J, Lambert AP, ... ... Lernmark A, et al. Relative predispositional effects of HLA class II DRB1-DQB1 haplotypes and genotypes on type 1 diabetes: a meta-analysis. Tissue Antigens. 70: 110-27. PMID 17610416 DOI: 10.1111/J.1399-0039.2007.00867.X  0.399
2007 Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA. Low-density cells isolated from the rat thymus resemble branched cortical macrophages and have a reduced capability of rescuing double-positive thymocytes from apoptosis in the BB-DP rat. Journal of Leukocyte Biology. 82: 869-76. PMID 17599904 DOI: 10.1189/Jlb.0407213  0.348
2007 Sedimbi SK, Luo XR, Sanjeevi CB, Lernmark A, Landin-Olsson M, Arnqvist H, Björck E, Nyström L, Ohlson LO, Scherstén B, Ostman J, Aili M, Bååth LE, et al. SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients. Genes and Immunity. 8: 518-21. PMID 17554341 DOI: 10.1038/Sj.Gene.6364406  0.412
2007 Bekris LM, Shephard C, Janer M, Graham J, McNeney B, Shin J, Zarghami M, Griffith W, Farin F, Kavanagh TJ, Lernmark A. Glutamate cysteine ligase catalytic subunit promoter polymorphisms and associations with type 1 diabetes age-at-onset and GAD65 autoantibody levels. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 115: 221-8. PMID 17479437 DOI: 10.1055/S-2007-970574  0.393
2007 Laine AP, Holmberg H, Nilsson A, Ortqvist E, Kiviniemi M, Vaarala O, Akerblom HK, Simell O, Knip M, Ludvigsson J, Ivarsson SA, Larsson K, Lernmark A, Ilonen J. Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations. Disease Markers. 23: 139-45. PMID 17473382 DOI: 10.1155/2007/574363  0.433
2007 Larsson HE, Lynch K, Lernmark B, Hansson G, Lernmark A, Ivarsson SA. Relationship between increased relative birthweight and infections during pregnancy in children with a high-risk diabetes HLA genotype. Diabetologia. 50: 1161-9. PMID 17406854 DOI: 10.1007/S00125-007-0648-6  0.39
2007 Niklasson B, Hultman T, Kallies R, Niedrig M, Nilsson R, Berggren P, Juntti-Berggren L, Efendic S, Lernmark Å, Klitz W. The BioBreeding rat diabetes model is infected with Ljungan virus. Diabetologia. 50: 1559-1560. PMID 17406852 DOI: 10.1007/S00125-007-0659-3  0.353
2007 Bekris LM, Jensen RA, Lagerquist E, Hall TR, Agardh CD, Cilio CM, Lethagen AL, Lernmark A, Robertson JA, Hampe CS. GAD65 autoantibody epitopes in adult patients with latent autoimmune diabetes following GAD65 vaccination. Diabetic Medicine : a Journal of the British Diabetic Association. 24: 521-6. PMID 17367313 DOI: 10.1111/J.1464-5491.2007.02091.X  0.44
2007 Shaat N, Lernmark A, Karlsson E, Ivarsson S, Parikh H, Berntorp K, Groop L. A variant in the transcription factor 7-like 2 (TCF7L2) gene is associated with an increased risk of gestational diabetes mellitus. Diabetologia. 50: 972-9. PMID 17342473 DOI: 10.1007/S00125-007-0623-2  0.513
2007 Hoeldtke RD, Hampe CS, Bekris LM, Hobbs G, Bryner KD, Lernmark A. Antibodies to GAD65 and peripheral nerve function in the DCCT. Journal of Neuroimmunology. 185: 182-9. PMID 17328966 DOI: 10.1016/J.Jneuroim.2007.01.009  0.379
2007 Rui M, Hampe CS, Wang C, Ling Z, Gorus FK, Lernmark A, Pipeleers DG, De Pauw PE. Species and epitope specificity of two 65 kDa glutamate decarboxylase time-resolved fluorometric immunoassays. Journal of Immunological Methods. 319: 133-43. PMID 17210161 DOI: 10.1016/J.Jim.2006.11.007  0.358
2007 Agardh D, Nilsson A, Carlsson A, Kockum I, Lernmark A, Ivarsson SA. Tissue transglutaminase autoantibodies and human leucocyte antigen in Down's syndrome patients with coeliac disease. Acta Paediatrica. 91: 34-38. PMID 11883815 DOI: 10.1080/080352502753457914  0.315
2006 Lernmark B, Lynch K, Lernmark Å. Cord Blood Islet Autoantibodies Are Related to Stress in the Mother during Pregnancy Annals of the New York Academy of Sciences. 1079: 345-349. PMID 17130577 DOI: 10.1196/Annals.1375.053  0.375
2006 Hagopian WA, Lernmark Å, Rewers MJ, Simell OG, She JX, Ziegler AG, Krischer JP, Akolkar B. TEDDY- The environmental determinants of diabetes in the young - An observational clinical trial Annals of the New York Academy of Sciences. 1079: 320-326. PMID 17130573 DOI: 10.1196/Annals.1375.049  0.433
2006 Gupta M, Graham J, McNeeny B, Zarghami M, Landin-Olsson M, Hagopian WA, Palmer J, Lernmark A, Sanjeevi CB. MHC class I chain-related gene-A is associated with IA2 and IAA but not GAD in Swedish type 1 diabetes mellitus. Annals of the New York Academy of Sciences. 1079: 229-39. PMID 17130560 DOI: 10.1196/Annals.1375.036  0.426
2006 Fuller JM, Kwitek AE, Hawkins TJ, Moralejo DH, Lu W, Tupling TD, MacMurray AJ, Borchardt G, Hasinoff M, Lernmark A. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats Diabetes. 55: 3351-3357. PMID 17130479 DOI: 10.2337/Db06-0715  0.412
2006 Balasubramanyam A, Garza G, Rodriguez L, Hampe CS, Gaur LK, Lernmark Å, Maldonado MR. Accuracy and predictive value of classification schemes for ketosis-prone diabetes Diabetes Care. 29: 2575-2579. PMID 17130187 DOI: 10.2337/Dc06-0749  0.37
2006 Holm BC, Svensson J, Åkesson C, Arvastsson J, Ljungberg J, Lynch K, Ivarsson S, Lernmark Å, Cilio CM. Evidence for immunological priming and increased frequency of CD4(+) CD25(+) cord blood T cells in children born to mothers with type 1 diabetes. Clinical and Experimental Immunology. 146: 493-502. PMID 17100770 DOI: 10.1111/J.1365-2249.2006.03243.X  0.407
2006 Geoffrey R, Jia S, Kwitek AE, Woodliff J, Ghosh S, Lernmark A, Wang X, Hessner MJ. Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. Journal of Immunology (Baltimore, Md. : 1950). 177: 7275-86. PMID 17082646 DOI: 10.4049/Jimmunol.177.10.7275  0.439
2006 Gebe JA, Unrath KA, Falk BA, Ito K, Wen L, Daniels TL, Lernmark A, Nepom GT. Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice. Clinical Immunology (Orlando, Fla.). 121: 294-304. PMID 16979383 DOI: 10.1016/J.Clim.2006.08.002  0.467
2006 Roach JC, Deutsch K, Li S, Siegel AF, Bekris LM, Einhaus DC, Sheridan CM, Glusman G, Hood L, Lernmark A, Janer M. Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. American Journal of Human Genetics. 79: 614-27. PMID 16960798 DOI: 10.1086/507876  0.399
2006 Zangeneh F, Arora PS, Dyck PJ, Bekris L, Lernmark A, Achenbach SJ, Oberg AL, Rizza RA. Effects of duration of type 2 diabetes mellitus on insulin secretion. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 12: 388-93. PMID 16939949 DOI: 10.4158/Ep.12.4.388  0.513
2006 Niklasson B, Samsioe A, Blixt M, Sandler S, Sjöholm A, Lagerquist E, Lernmark Å, Klitz W. Prenatal viral exposure followed by adult stress produces glucose intolerance in a mouse model Diabetologia. 49: 2192-2199. PMID 16821045 DOI: 10.1007/S00125-006-0339-8  0.363
2006 Shaat N, Karlsson E, Lernmark A, Ivarsson S, Lynch K, Parikh H, Almgren P, Berntorp K, Groop L. Common variants in MODY genes increase the risk of gestational diabetes mellitus. Diabetologia. 49: 1545-51. PMID 16752173 DOI: 10.1007/S00125-006-0258-8  0.443
2006 Bekris LM, Kavanagh TJ, Lernmark A. Targeting type 1 diabetes before and at the clinical onset of disease. Endocrine, Metabolic & Immune Disorders Drug Targets. 6: 103-24. PMID 16611168 DOI: 10.2174/187153006776056576  0.453
2006 Sanjeevi C, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark Å. The combination of several polymorphic amino acid residues in the DQ alpha and DQ beta chains forms a domain structure pattern and is associated with insulin-dependent diabetes mellitus Annals of the New York Academy of Sciences. 958: 362-375. PMID 12021143 DOI: 10.1111/J.1749-6632.2002.Tb03006.X  0.318
2006 Holm B, Lindholm E, Lynch K, Bakhatadze E, Arvastsson J, Lernmark A, Agardh C, Cilio C. Su.27. Association of Foxp3 Polymorphism with Gad65 Autoantibodies in Type 1 Diabetes Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.454  0.477
2005 Bekris LM, Shephard C, Peterson M, Hoehna J, Van Yserloo B, Rutledge E, Farin F, Kavanagh TJ, Lernmark A. Glutathione-s-transferase M1 and T1 polymorphisms and associations with type 1 diabetes age-at-onset. Autoimmunity. 38: 567-75. PMID 16390810 DOI: 10.1080/08916930500407238  0.467
2005 Shaat N, Ekelund M, Lernmark Å, Ivarsson S, Almgren P, Berntorp K, Groop L. Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus Diabetologia. 48: 2544-2551. PMID 16320083 DOI: 10.1007/S00125-005-0035-0  0.518
2005 Valdes AM, Thomson G, Graham J, Zarghami M, McNeney B, Kockum I, Smith A, Lathrop M, Steenkiste AR, Dorman JS, Noble JA, Hansen JA, Pugliese A, Lernmark A. D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus Diabetologia. 48: 2540-2543. PMID 16320082 DOI: 10.1007/S00125-005-0011-8  0.432
2005 Pihoker C, Gilliam LK, Hampe CS, Lernmark Å. Autoantibodies in diabetes. Diabetes. 54: 52-61. PMID 16306341 DOI: 10.2337/Diabetes.54.Suppl_2.S52  0.531
2005 Hawkins T, Fuller J, Olson K, Speros S, Lernmark A. DR.lyp/lyp bone marrow maintains lymphopenia and promotes diabetes in lyp/lyp but not in +/+ recipient DR.lyp BB rats. Journal of Autoimmunity. 25: 251-7. PMID 16246525 DOI: 10.1016/J.Jaut.2005.06.003  0.405
2005 Åkesson K, Nyström L, Färnkvist L, Ostman J, Lernmark Å, Kockum I. Increased risk of diabetes among relatives of female insulin-treated patients diagnosed at 15-34 years of age Diabetic Medicine. 22: 1551-1557. PMID 16241921 DOI: 10.1111/J.1464-5491.2005.01694.X  0.447
2005 Lernmark A, Agardh CD. Immunomodulation with human recombinant autoantigens. Trends in Immunology. 26: 608-12. PMID 16153889 DOI: 10.1016/J.It.2005.08.015  0.544
2005 Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA. Aberrancies in the differentiation and maturation of dendritic cells from bone-marrow precursors are linked to various genes on chromosome 4 and other chromosomes of the BB-DP rat. Journal of Autoimmunity. 25: 1-12. PMID 16023326 DOI: 10.1016/J.Jaut.2005.05.002  0.328
2005 Agardh CD, Cilio CM, Lethagen A, Lynch K, Leslie RD, Palmér M, Harris RA, Robertson JA, Lernmark A. Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes. Journal of Diabetes and Its Complications. 19: 238-46. PMID 15993359 DOI: 10.1016/J.Jdiacomp.2004.12.003  0.409
2005 Larsson HE, Lynch K, Lernmark B, Nilsson A, Hansson G, Almgren P, Lernmark A, Ivarsson SA. Diabetes-associated HLA genotypes affect birthweight in the general population. Diabetologia. 48: 1484-91. PMID 15991024 DOI: 10.1007/S00125-005-1813-4  0.498
2005 Lernmark Å. Type 1 diabetes--does suppressing T cells increase insulin? The New England Journal of Medicine. 352: 2642-2644. PMID 15972873 DOI: 10.1056/Nejme058114  0.512
2005 Padoa CJ, Crowther NJ, Thomas JW, Hall TR, Bekris LM, Torn C, Landin-Olsson M, Ortqvist E, Palmer JP, Lernmark A, Hampe CS. Epitope analysis of insulin autoantibodies using recombinant Fab. Clinical and Experimental Immunology. 140: 564-71. PMID 15932520 DOI: 10.1111/J.1365-2249.2005.02802.X  0.471
2005 Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA. Defects in differentiation of bone-marrow derived dendritic cells of the BB rat are partly associated with IDDM2 (the lyp gene) and partly associated with other genes in the BB rat background. Journal of Autoimmunity. 25: 46-56. PMID 15922563 DOI: 10.1016/J.Jaut.2005.03.008  0.356
2005 Lernmark A. Type 1 diabetes as a model for prediction and diagnosis. Autoimmunity. 37: 341-5. PMID 15518056 DOI: 10.1080/08916930410001726012  0.435
2005 Luo D, Rogers CN, Steed JT, Gilliam LK, Hampe CS, Lernmark A. Development of glutamic acid decarboxylase 65 (GAD65) autoantibody assay using biotin-GAD65 fusion protein. Journal of Biotechnology. 111: 97-104. PMID 15196774 DOI: 10.1016/J.Jbiotec.2004.03.009  0.382
2005 Thomson G, Valdes AM, Dorman JS, Steenkiste A, Noble JA, Concannon P, Smith AG, John H, Lernmark A, Pugliese A. The HLA component of type 1 diabetes Human Immunology. 66: 64. DOI: 10.1016/J.Humimm.2005.08.122  0.481
2004 Veitenhansl M, Stegner K, Hierl FX, Dieterle C, Feldmeier H, Gutt B, Landgraf R, Garrow AP, Vileikyte L, Findlow A, Waterman C, Boulton AJ, Shankhdhar K, Shankhdhar L, Shankhdhar U, et al. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 47: A1-A464. PMID 27770180 DOI: 10.1007/Bf03375463  0.454
2004 Sweet IR, Cook DL, Lernmark A, Greenbaum CJ, Krohn KA. Non-invasive imaging of beta cell mass: a quantitative analysis. Diabetes Technology & Therapeutics. 6: 652-9. PMID 15628819 DOI: 10.1089/Dia.2004.6.652  0.321
2004 Hessner MJ, Wang X, Meyer L, Geoffrey R, Jia S, Fuller J, Lernmark A, Ghosh S. Involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the BioBreeding rat. Journal of Immunology (Baltimore, Md. : 1950). 173: 6993-7002. PMID 15557196 DOI: 10.4049/Jimmunol.173.11.6993  0.441
2004 Maioli M, Alejandro E, Tonolo G, Gilliam LK, Bekris L, Hampe CS, Obinu DA, Manconi A, Puddu L, Lynch K, Lernmark A. Epitope-restricted 65-kilodalton glutamic acid decarboxylase autoantibodies among new-onset Sardinian type 2 diabetes patients define phenotypes of autoimmune diabetes. The Journal of Clinical Endocrinology and Metabolism. 89: 5675-82. PMID 15531528 DOI: 10.1210/Jc.2004-0864  0.425
2004 Larsson K, Elding-Larsson H, Cederwall E, Kockum K, Neiderud J, Sjöblad S, Lindberg B, Lernmark B, Cilio C, Ivarsson SA, Lernmark A. Genetic and perinatal factors as risk for childhood type 1 diabetes. Diabetes/Metabolism Research and Reviews. 20: 429-37. PMID 15386804 DOI: 10.1002/Dmrr.506  0.501
2004 Luo D, Gilliam LK, Greenbaum C, Bekris L, Hampe CS, Daniels T, Richter W, Marcovina SM, Rolandsson O, Landin-Olsson M, Kockum I, Lernmark A. Conformation-dependent GAD65 autoantibodies in diabetes. Diabetologia. 47: 1581-91. PMID 15365614 DOI: 10.1007/S00125-004-1495-3  0.451
2004 Shaat N, Ekelund M, Lernmark Å, Ivarsson S, Nilsson A, Perfekt R, Berntorp K, Groop L. Genotypic and phenotypic differences between Arabian and Scandinavian women with gestational diabetes mellitus. Diabetologia. 47: 878-884. PMID 15095040 DOI: 10.1007/S00125-004-1388-5  0.486
2004 Agardh E, Gaur LK, Lernmark A, Agardh CD. HLA-DRB1, -DQA1, and -DQB1 subtypes or ACE gene polymorphisms do not seem to be risk markers for severe retinopathy in younger Type 1 diabetic patients. Journal of Diabetes and Its Complications. 18: 32-6. PMID 15019597 DOI: 10.1016/S1056-8727(03)00040-0  0.486
2004 Sweet IR, Cook DL, Lernmark A, Greenbaum CJ, Wallen AR, Marcum ES, Stekhova SA, Krohn KA. Systematic screening of potential beta-cell imaging agents. Biochemical and Biophysical Research Communications. 314: 976-83. PMID 14751228 DOI: 10.1016/J.Bbrc.2003.12.182  0.309
2003 Boutin P, Dina C, Vasseur F, Dubois S, Corset L, Séron K, Bekris L, Cabellon J, Neve B, Vasseur-Delannoy V, Chikri M, Charles MA, Clement K, Lernmark A, Froguel P. GAD2 on chromosome 10p12 is a candidate gene for human obesity Plos Biology. 1. PMID 14691540 DOI: 10.1371/Journal.Pbio.0000068  0.311
2003 Niklasson B, Hörnfeldt B, Nyholm E, Niedrig M, Donoso‐Mantke O, Gelderblom HR, Lernmark Å. Type 1 Diabetes in Swedish Bank Voles (Clethrionomys glareolus): Signs of Disease in Both Colonized and Wild Cyclic Populations at Peak Density Annals of the New York Academy of Sciences. 1005: 170-175. PMID 14679053 DOI: 10.1196/Annals.1288.020  0.482
2003 Moralejo DH, Park HA, Speros SJ, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat. Journal of Autoimmunity. 21: 315-24. PMID 14624755 DOI: 10.1016/S0896-8411(03)00138-0  0.335
2003 Maldonado M, Hampe CS, Gaur LK, D'Amico S, Iyer D, Hammerle LP, Bolgiano D, Rodriguez L, Rajan A, Lernmark A, Balasubramanyam A. Ketosis-prone diabetes: dissection of a heterogeneous syndrome using an immunogenetic and beta-cell functional classification, prospective analysis, and clinical outcomes. The Journal of Clinical Endocrinology and Metabolism. 88: 5090-8. PMID 14602731 DOI: 10.1210/Jc.2003-030180  0.454
2003 Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, Kitzmiller J, Knowler WC, Lebovitz H, Lernmark A, Nathan D, Palmer J, Rizza R, Saudek C, Shaw J, et al. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care. 26: 3160-7. PMID 14578255 DOI: 10.2337/Diacare.26.11.3160  0.463
2003 Elfving AM, Lindberg BA, Nyström L, Sundkvist G, Lernmark A, Ivarsson SA. Islet autoantibodies in cord blood from patients who developed type 1 diabetes mellitus at 15-30 years of age. Autoimmunity. 36: 227-31. PMID 14563016 DOI: 10.1080/0891693031000141040  0.512
2003 Kobayashi T, Tanaka S, Okubo M, Nakanishi K, Murase T, Lernmark A. Unique epitopes of glutamic acid decarboxylase autoantibodies in slowly progressive type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 88: 4768-75. PMID 14557453 DOI: 10.1210/Jc.2002-021529  0.43
2003 Carroll AD, Scampavia L, Luo D, Lernmark A, Ruzicka J. Bead injection ELISA for the determination of antibodies implicated in type 1 diabetes mellitus. The Analyst. 128: 1157-62. PMID 14529023 DOI: 10.1039/B302786D  0.381
2003 Mundinger TO, Mei Q, Figlewicz DP, Lernmark A, Taborsky GJ. Impaired glucagon response to sympathetic nerve stimulation in the BB diabetic rat: effect of early sympathetic islet neuropathy. American Journal of Physiology. Endocrinology and Metabolism. 285: E1047-54. PMID 12876072 DOI: 10.1152/Ajpendo.00136.2003  0.375
2003 Niklasson B, Heller KE, Schønecker B, Bildsøe M, Daniels T, Hampe CS, Widlund P, Simonson WT, Schaefer JB, Rutledge E, Bekris L, Lindberg AM, Johansson S, Ortqvist E, Persson B, ... Lernmark A, et al. Development of type 1 diabetes in wild bank voles associated with islet autoantibodies and the novel ljungan virus. International Journal of Experimental Diabesity Research. 4: 35-44. PMID 12745669 DOI: 10.1080/15438600303733  0.497
2003 Gupta M, Nikitina-Zake L, Zarghami M, Landin-Olsson M, Kockum I, Lernmark A, Sanjeevi CB. Association between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden. Human Immunology. 64: 553-61. PMID 12691706 DOI: 10.1016/S0198-8859(03)00035-1  0.334
2003 Rolandsson O, Hägg E, Janer M, Rutledge E, Gaur LK, Nilsson M, Hallmans G, Lernmark A. High GAD65 autoantibody levels in nondiabetic adults are associated with HLA but not with CTLA-4 or INS VNTR Journal of Internal Medicine. 253: 447-453. PMID 12653874 DOI: 10.1046/J.1365-2796.2003.01115.X  0.416
2002 Lam-Tse W, Lernmark Å, Drexhage H. Animal models of endocrine/organ-specific autoimmune diseases: do they really help us to understand human autoimmunity? Springer Seminars in Immunopathology. 24: 297-321. PMID 12503056 DOI: 10.1007/S00281-002-0110-2  0.323
2002 Rolandsson O, Haney MF, Hagg E, Biber B, Lernmark A. Streptozotocin induced diabetes in minipig: a case report of a possible model for type 1 diabetes? Autoimmunity. 35: 261-4. PMID 12482194 DOI: 10.1080/0891693021000010703  0.477
2002 Plesner A, Greenbaum CJ, Gaur LK, Ernst RK, Lernmark A. Macrophages from high-risk HLA-DQB1*0201/*0302 type 1 diabetes mellitus patients are hypersensitive to lipopolysaccharide stimulation. Scandinavian Journal of Immunology. 56: 522-9. PMID 12410803 DOI: 10.1046/J.1365-3083.2002.01150.X  0.417
2002 Mei Q, Mundinger TO, Lernmark A, Taborsky GJ. Early, selective, and marked loss of sympathetic nerves from the islets of BioBreeder diabetic rats. Diabetes. 51: 2997-3002. PMID 12351439 DOI: 10.1046/J.1529-8027.2003.03016_15.X  0.477
2002 Sims TJ, Lernmark A, Mancl LA, Schifferle RE, Page RC, Persson GR. Serum IgG to heat shock proteins and Porphyromonas gingivalis antigens in diabetic patients with periodontitis. Journal of Clinical Periodontology. 29: 551-62. PMID 12296783 DOI: 10.1034/J.1600-051X.2002.290612.X  0.416
2002 Hampe CS, Kockum I, Landin-Olsson M, Törn C, Ortqvist E, Persson B, Rolandsson O, Palmer J, Lernmark A. GAD65 antibody epitope patterns of type 1.5 diabetic patients are consistent with slow-onset autoimmune diabetes Diabetes Care. 25: 1481-1482. PMID 12145258 DOI: 10.2337/Diacare.25.8.1481  0.53
2002 MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, ... ... Lernmark A, et al. Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Research. 12: 1029-39. PMID 12097339 DOI: 10.1101/Gr.412702  0.453
2002 Gaur LK, Kennedy E, Nitta Y, Nepom GT, Nelson KA, Allen M, Lernmark A. Induction of donor-specific tolerance to islet allografts in nonhuman primates. Annals of the New York Academy of Sciences. 958: 194-8. PMID 12021105 DOI: 10.1111/J.1749-6632.2002.Tb02968.X  0.439
2002 Sweet IR, Cook DL, Wiseman RW, Greenbaum CJ, Lernmark A, Matsumoto S, Teague JC, Krohn KA. Dynamic perifusion to maintain and assess isolated pancreatic islets. Diabetes Technology & Therapeutics. 4: 67-76. PMID 12017423 DOI: 10.1089/15209150252924111  0.346
2002 Mohatt J, Gilliam LK, Bekris L, Ebbesson S, Lernmark A. Type 1 diabetes-related autoantibodies are rare in Alaska native populations International Journal of Circumpolar Health. 61: 21-31. PMID 12002943 DOI: 10.3402/Ijch.V61I1.17402  0.49
2002 Lernmark Å. Multiple sclerosis and type 1 diabetes: an unlikely alliance The Lancet. 359: 1450-1451. PMID 11988239 DOI: 10.1016/S0140-6736(02)08464-7  0.465
2002 Simonson W, Ramanathan S, Bieg S, Poussier P, Lernmark A. Protein-free diets do not protect high-incidence diabetes-prone BioBreeding rats from diabetes. Metabolism-Clinical and Experimental. 51: 569-574. PMID 11979387 DOI: 10.1053/Meta.2002.31979  0.416
2002 Graham J, Hagopian WA, Kockum I, Li LS, Sanjeevi CB, Lowe RM, Schaefer JB, Zarghami M, Day HL, Landin-Olsson M, Palmer JP, Janer-Villanueva M, Hood L, Sundkvist G, Lernmark A, et al. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes. 51: 1346-55. PMID 11978629 DOI: 10.2337/Diabetes.51.5.1346  0.471
2002 Clark L, Greenbaum C, Jiang J, Lernmark A, Ochs H. The antibody response to bacteriophage is linked to the lymphopenia gene in congenic BioBreeding rats. Fems Immunology and Medical Microbiology. 32: 205-9. PMID 11934565 DOI: 10.1111/J.1574-695X.2002.Tb00555.X  0.31
2002 Lernmark A. Controlling the controls: GAD65 autoreactive T cells in type 1 diabetes. The Journal of Clinical Investigation. 109: 869-70. PMID 11927613 DOI: 10.1172/JCI15381  0.314
2002 Maioli M, Tonolo G, Bekris L, Cirillo R, Schranz D, Cossu E, Ciccarese M, Lernmark A. GAD65 and IA-2 autoantibodies are common in a subset of siblings of Sardinian Type 2 diabetes families. Diabetes Research and Clinical Practice. 56: 41-7. PMID 11879720 DOI: 10.1016/S0168-8227(01)00348-5  0.488
2002 Hampe CS, Hammerle LP, Bekris L, Ortqvist E, Persson B, Lernmark A. Stable GAD65 autoantibody epitope patterns in type 1 diabetes children five years after onset. Journal of Autoimmunity. 18: 49-53. PMID 11869046 DOI: 10.1006/Jaut.2001.0564  0.499
2002 Graham J, Kockum I, Sanjeevi CB, Landin-Olsson M, Nyström L, Sundkvist G, Arnqvist H, Blohmé G, Lithner F, Littorin B, Scherstén B, Wibell L, Östman J, Lernmark Å, Breslow N. Negative association between type 1 diabetes and HLA DQB1*0602-DQA1*0102 is attenuated with age at onset European Journal of Immunogenetics. 26: 117-127. DOI: 10.1111/J.1600-0609.2006.00789.X-I1  0.48
2001 Agardh D, Nilsson A, Tuomi T, Lindberg B, Carlsson AK, Lernmark A, Ivarsson SA. Prediction of silent celiac disease at diagnosis of childhood type 1 diabetes by tissue transglutaminase autoantibodies and HLA. Pediatric Diabetes. 2: 58-65. PMID 15016199 DOI: 10.1034/J.1399-5448.2001.002002058.X  0.461
2001 Halban PA, Kahn SE, Lernmark Å, Rhodes CJ. Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set? Diabetes. 50: 2181-2191. PMID 11574396 DOI: 10.2337/Diabetes.50.10.2181  0.417
2001 Uibo R, Sullivan EP, Uibo O, Lernmark A, Salur L, Kivik T, Mandel M. Comparison of the prevalence of glutamic acid decarboxylase (GAD65) and gliadin antibodies (AGA) in a randomly selected adult estonian population. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 33: 564-7. PMID 11561218 DOI: 10.1055/S-2001-17215  0.436
2001 Novak EJ, Masewicz SA, Liu AW, Lernmark A, Kwok WW, Nepom GT. Activated human epitope-specific T cells identified by class II tetramers reside within a CD4high, proliferating subset. International Immunology. 13: 799-806. PMID 11369708 DOI: 10.1093/Intimm/13.6.799  0.748
2001 Sims TJ, Lernmark A, Smith T, Page RC, Persson GR. Treatment outcome for IDDM patients in relation to glutamic acid decarboxylase autoantibodies and serum IgG to periodontal pathogens. Journal of Clinical Periodontology. 28: 550-7. PMID 11350522 DOI: 10.1034/J.1600-051X.2001.028006550.X  0.353
2001 Rolandsson O, Hägg E, Nilsson M, Hallmans G, Mincheva-Nilsson L, Lernmark A. Prediction of diabetes with body mass index, oral glucose tolerance test and islet cell autoantibodies in a regional population Journal of Internal Medicine. 249: 279-288. PMID 11298847 DOI: 10.1046/J.1365-2796.2001.00813.X  0.47
2001 Törn C, Landin-Olsson M, Lernmark A, Scherstén B, Ostman J, Arnqvist HJ, Björk E, Blohmé G, Bolinder J, Eriksson J, Littorin B, Nyström L, Sundkvist G. Combinations of beta cell specific autoantibodies at diagnosis of diabetes in young adults reflects different courses of beta cell damage. Autoimmunity. 33: 115-20. PMID 11264790 DOI: 10.3109/08916930108995996  0.374
2001 Gaur LK, Nepom GT, Lernmark A. Low-dose streptozotocin induces sustained hyperglycemia in Macaca nemestrina. Autoimmunity. 33: 103-14. PMID 11264789 DOI: 10.3109/08916930108995995  0.436
2001 Barry SC, Ramesh N, Lejnieks DV, Simonson WT, Kemper L, Lernmark A, Osborne WRA. Glucose-regulated insulin expression in diabetic rats Human Gene Therapy. 12: 131-139. PMID 11177550 DOI: 10.1089/104303401750061195  0.404
2001 Hampe CS, Hammerle LP, Falorni A, Robertson J, Lernmark A. Site-directed mutagenesis of K396R of the 65 kDa glutamic acid decarboxylase active site obliterates enzyme activity but not antibody binding. Febs Letters. 488: 185-9. PMID 11163769 DOI: 10.1016/S0014-5793(00)02429-7  0.405
2001 Sacks DB, Lernmark A. Molecular manipulation of autoantibody testing in type 1 diabetes: two for one. Clinical Chemistry. 47: 803-804. DOI: 10.1093/Clinchem/47.5.803  0.52
2000 Hampe CS, Hammerle LP, Bekris L, Örtqvist E, Kockum I, Rolandsson O, Landin-Olsson M, Torn C, Persson B, Lernmark A. Recognition of glutamic acid decarboxylase (GAD) by autoantibodies from different GAD antibody-positive phenotypes Journal of Clinical Endocrinology and Metabolism. 85: 4671-4679. PMID 11134126 DOI: 10.1210/Jcem.85.12.7070  0.472
2000 Törn C, Landin-Olsson M, Ostman J, Scherstén B, Arnqvist H, Blohmé G, Björk E, Bolinder J, Eriksson J, Littorin B, Nyström L, Sundkvist G, Lernmark A. Glutamic acid decarboxylase antibodies (GADA) is the most important factor for prediction of insulin therapy within 3 years in young adult diabetic patients not classified as Type 1 diabetes on clinical grounds. Diabetes/Metabolism Research and Reviews. 16: 442-47. PMID 11114103 DOI: 10.1002/1520-7560(2000)9999:9999<::Aid-Dmrr152>3.0.Co;2-T  0.507
2000 Lowe RM, Graham J, Sund G, Kockum I, Landin-Olsson M, Schaefer JB, Törn C, Lernmark A, Dahlquist G. The length of the CTLA-4 microsatellite (AT)N-repeat affects the risk for type 1 diabetes. Diabetes Incidence in Sweden Study Group. Autoimmunity. 32: 173-80. PMID 11092697 DOI: 10.3109/08916930008994090  0.478
2000 Mire-Sluis AR, Das RG, Lernmark A. The World Health Organization International Collaborative Study for islet cell antibodies. Diabetologia. 43: 1282-1292. PMID 11079747 DOI: 10.1007/S001250051524  0.381
2000 Reijonen H, Daniels TL, Lernmark A, Nepom GT. GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65. Diabetes. 49: 1621-6. PMID 11016444 DOI: 10.2337/Diabetes.49.10.1621  0.376
2000 Hoeldtke RD, Bryner KD, Hobbs GR, Horvath GG, Riggs JE, Christie I, Ganser G, Marcovina SM, Lernmark A. Antibodies to glutamic acid decarboxylase and peripheral nerve function in type 1 diabetes Journal of Clinical Endocrinology and Metabolism. 85: 3297-3308. PMID 10999825 DOI: 10.1210/Jcem.85.9.6830  0.341
2000 Marcovina SM, Landin-Olsson M, Essen-Möller A, Palmer JP, Lernmark Å. Evaluation of a novel radioimmunoassay using 125I-labelled human recombinant GAD65 for the determination of glutamic acid decarboxylase (GAD65) autoantibodies. International Journal of Clinical & Laboratory Research. 30: 21-26. PMID 10984128 DOI: 10.1007/S005990070029  0.469
2000 Novak EJ, Ortqvist E, Nord E, Edwall L, Hampe CS, Bekris L, Persson BE, Lernmark A. Stability of disease-associated antibody titers in pregnant women with type 1 diabetes with or without residual beta-cell function. Diabetes Care. 23: 1019-21. PMID 10895858 DOI: 10.2337/Diacare.23.7.1019  0.788
2000 Ostman J, Landin-Olsson M, Törn C, Palmer J, Lernmark A, Arnqvist H, Björk E, Bolinder J, Blohmé G, Eriksson J, Littorin B, Nyström L, Scherstén B, Sundkvist G, Wibell L. Ketoacidosis in young adults is not related to the islet antibodies at the diagnosis of Type 1 diabetes mellitus--a nationwide study. Diabetic Medicine : a Journal of the British Diabetic Association. 17: 269-74. PMID 10821292 DOI: 10.1046/J.1464-5491.2000.00265.X  0.54
2000 Chessler SD, Lernmark A. Alternative splicing of GAD67 results in the synthesis of a third form of glutamic-acid decarboxylase in human islets and other non-neural tissues. The Journal of Biological Chemistry. 275: 5188-92. PMID 10671565 DOI: 10.1074/Jbc.275.7.5188  0.317
2000 Lernmark Å. Rapid-onset type 1 diabetes with pancreatic exocrine dysfunction. The New England Journal of Medicine. 342: 344-345. PMID 10655534 DOI: 10.1056/Nejm200002033420508  0.521
2000 Bieg S, Simonson WT, Ellefsen K, Lernmark Å. Rel B is an early marker of autoimmune islet inflammation in the biobreeding (BB) rat. Pancreas. 20: 47-54. PMID 10630383 DOI: 10.1097/00006676-200001000-00007  0.371
2000 Törn C, Landin-Olsson M, Lernmark Å, Palmer JP, Arnqvist HJ, Blohmé G, Lithner F, Littorin B, Nyström L, Scherstén B, Sundkvist G, Wibell L, Östman J. Prognostic Factors for the Course of β Cell Function in Autoimmune Diabetes The Journal of Clinical Endocrinology and Metabolism. 85: 4619-4623. DOI: 10.1210/Jc.85.12.4619  0.435
2000 Chung C, Huh K, Lernmark Å. Heterogeneity of diabetes in adult Korean patients Diabetes Research and Clinical Practice. 50: 106. DOI: 10.1016/S0168-8227(00)81819-7  0.433
2000 Lernmark Å, Graham J, Lowe R, Kockum I, Landin-Olsson M. Type 1 diabetes genes and islet cell autoantibodies in different cominations predict age at onset Diabetes Research and Clinical Practice. 50: 89-90. DOI: 10.1016/S0168-8227(00)81761-1  0.462
1999 Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F, Juhl C, ... ... Lernmark A, et al. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 42: A1-A330. PMID 27770183 DOI: 10.1007/Bf03375458  0.453
1999 Hao W, Daniels T, Pipeleers DG, Smismans A, Reijonen H, Nepom GT, Lernmark A. Radioimmunoassay for glutamic acid decarboxylase-65. Diabetes Technology & Therapeutics. 1: 13-20. PMID 11475299 DOI: 10.1089/152091599317521  0.42
1999 Lindberg B, Carlsson A, Ericsson UB, Kockum I, Lernmark A, Landin-Olsson M, Sundkvist G, Ivarsson SA. Prevalence of beta-cell and thyroid autoantibody positivity in schoolchildren during three-year follow-up. Autoimmunity. 31: 175-85. PMID 10739334 DOI: 10.3109/08916939908994062  0.316
1999 Undlien DE, Kockum I, Rønningen KS, Lowe R, Saanjeevi CB, Graham J, Lie BA, Akselsen HE, Lernmark Å, Thorsby E. HLA associations in type 1 diabetes among patients not carrying high-risk DR3-DQ2 or DR4-DQ8 haplotypes. Tissue Antigens. 54: 543-551. PMID 10674967 DOI: 10.1034/J.1399-0039.1999.540602.X  0.447
1999 Lernmark Å. Selecting culprits in type 1 diabetes β-cell killing Journal of Clinical Investigation. 104: 1487-1489. PMID 10587509 DOI: 10.1172/Jci8826  0.5
1999 Kockum I, Sanjeevi CB, Eastman S, Landin-Olsson M, Dahlquist G, Lernmark A. Complex interaction between HLA DR and DQ in conferring risk for childhood type 1 diabetes. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 26: 361-72. PMID 10553503 DOI: 10.1046/J.1365-2370.1999.00173.X  0.462
1999 Stobbe I, Duinkerken G, van Rood JJ, Lernmark A, Keymeulen B, Pipeleers D, De Vries RR, Glass FH, Roep BO. Tolerance to kidney allograft transplanted into Type I diabetic patients persists after in vivo challenge with pancreatic islet allografts that express repeated mismatches. Diabetologia. 42: 1379-80. PMID 10550427 DOI: 10.1007/S001250051456  0.412
1999 Lindberg B, Ivarsson SA, Lernmark A. Islet autoantibodies in cord blood could be a risk factor for future diabetes. Diabetologia. 42: 1375. PMID 10550423 DOI: 10.1007/S001250051452  0.42
1999 Hao W, Davis C, Hirsch IB, Eng LJ, Daniels T, Walsh D, Lernmark A. Plasmapheresis and immunosuppression in stiff-man syndrome with type 1 diabetes: a 2-year study. Journal of Neurology. 246: 731-5. PMID 10460456 DOI: 10.1007/S004150050443  0.47
1999 Klaff LS, Koike G, Jiang J, Wang Y, Bieg S, Pettersson A, Lander E, Jacob H, Lernmark Å. BB rat diabetes susceptibility and body weight regulation genes colocalize on Chromosome 2 Mammalian Genome. 10: 883-887. PMID 10441739 DOI: 10.1007/S003359901108  0.456
1999 Mire-Sluis AR, Das RG, Lernmark Å. The development of a World Health Organisation international standard for islet cell antibodies: the aims and design of an international collaborative study. Diabetes-Metabolism Research and Reviews. 15: 72-77. PMID 10398550 DOI: 10.1002/(Sici)1520-7560(199901/02)15:1<72::Aid-Dmrr11>3.0.Co;2-G  0.494
1999 Lindberg B, Ahlfors K, Carlsson A, Ericsson UB, Landin-Olsson M, Lernmark A, Ludvigsson J, Sundkvist G, Ivarsson SA. Previous exposure to measles, mumps, and rubella--but not vaccination during adolescence--correlates to the prevalence of pancreatic and thyroid autoantibodies. Pediatrics. 104: e12. PMID 10390298 DOI: 10.1542/Peds.104.1.E12  0.381
1999 Moore JK, Gold DP, Dreskin SC, Lernmark A, Bellgrau D. A diabetogenic gene prevents T cells from receiving costimulatory signals. Cellular Immunology. 194: 90-7. PMID 10357884 DOI: 10.1006/Cimm.1999.1501  0.319
1999 Rolandsson O, Hägg E, Hampe C, Sullivan EP, Nilsson M, Jansson G, Hallmans G, Lernmark A. Glutamate decarboxylase (GAD65) and tyrosine phosphatase-like protein (IA-2) autoantibodies index in a regional population is related to glucose intolerance and body mass index Diabetologia. 42: 555-559. PMID 10333047 DOI: 10.1007/S001250051194  0.389
1999 Littorin B, Sundkvist G, Hagopian W, Landin-Olsson M, Lernmark Å, Östman J, Arnqvist HJ, Blohme G, Bolinder J, Eriksson JW, Lithner F, Scherstén B, Wibell L. Islet cell and glutamic acid decarboxylase antibodies present at diagnosis of diabetes predict the need for insulin treatment. A cohort study in young adults whose disease was initially labeled as type 2 or unclassifiable diabetes. Diabetes Care. 22: 409-412. PMID 10097919 DOI: 10.2337/Diacare.22.3.409  0.483
1999 Roep BO, Stobbe I, Duinkerken G, van Rood JJ, Lernmark A, Keymeulen B, Pipeleers D, Claas FH, de Vries RR. Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients. Diabetes. 48: 484-90. PMID 10078547 DOI: 10.2337/Diabetes.48.3.484  0.434
1999 Lindberg B, Ivarsson SA, Landin-Olsson M, Sundkvist G, Svanberg L, Lernmark A. Islet autoantibodies in cord blood from children who developed type I (insulin-dependent) diabetes mellitus before 15 years of age. Diabetologia. 42: 181-7. PMID 10064098 DOI: 10.1007/S001250051137  0.502
1999 Landin-Olsson M, Arnqvist HJ, Blohmé G, Littorin B, Lithner F, Nyström L, Scherstén B, Sundkvist G, Wibell L, Östman J, Lernmark Å. Appearance of Islet Cell Autoantibodies after Clinical Diagnosis of Diabetes Mellitus Autoimmunity. 29: 57-63. PMID 10052686 DOI: 10.3109/08916939908995973  0.481
1999 Hampe CS, Ortqvist E, Rolandsson O, Landin-Olsson M, Törn C, Agren A, Persson B, Schranz DB, Lernmark A. Species-specific autoantibodies in type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 84: 643-8. PMID 10022431 DOI: 10.1210/Jcem.84.2.5503  0.526
1999 Lee ES, Jiang J, Sund GC, Simonson WT, Graham J, Dietsch G, Schimpf B, Bieg S, Peterman G, Lernmark A. Recombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat Diabetes. 48: 43-49. PMID 9892221 DOI: 10.2337/Diabetes.48.1.43  0.487
1999 Lernmark Å. Type 1 Diabetes Clinical Chemistry. 45: 1331-1338. DOI: 10.1159/000336412  0.516
1999 Lindberg B, Ivarsson SA, Lernmark A. Islet autoantibodies in cord blood could be a risk factor for future diabetes [5] Diabetologia. 42: 1443. DOI: 10.1007/s001250051320  0.306
1999 Lindberg B, Ivarsson SA, Lernmark Å. Influence of heredity on the appearance of islet autoantibodies in cordblood from children developing type I diabetes before 15 years of age [2] Diabetologia. 42: 896-897. DOI: 10.1007/Pl00002932  0.448
1998 Hirsch IB, D'Alessio D, Eng L, Davis C, Lernmark A, Chait A. Severe insulin resistance in a patient with type 1 diabetes and stiff-man syndrome treated with insulin lispro. Diabetes Research and Clinical Practice. 41: 197-202. PMID 9829349 DOI: 10.1016/S0168-8227(98)00072-2  0.423
1998 Agardh D, Agardh E, Landin-Olsson M, Gaur LK, Agardh C, Lernmark Å. Inverse relationship between GAD65 antibody levels and severe retinopathy in younger type 1 diabetic patients Diabetes Research and Clinical Practice. 40: 9-14. PMID 9699085 DOI: 10.1016/S0168-8227(98)00007-2  0.471
1998 Schranz DB, Bekris L, Landin-Olsson M, Törn C, Niläng A, Toll A, Grönlund H, Toivola B, Lernmark A. A simple and rapid microSepharose assay for GAD65 and ICA512 autoantibodies in diabetes. Diabetes Incidence Study in Sweden (DISS). Journal of Immunological Methods. 213: 87-97. PMID 9671127 DOI: 10.1016/S0022-1759(98)00025-8  0.512
1998 Schranz DB, Lernmark Å. Immunology in diabetes: an update Diabetes \/ Metabolism Reviews. 14: 3-29. PMID 9605628 DOI: 10.1002/(Sici)1099-0895(199803)14:1<3::Aid-Dmr206>3.0.Co;2-T  0.538
1998 Dotta F, Falorni A, Tiberti C, Dionisi S, Anastasi E, Torresi P, Lernmark A, Di Mario U. Autoantibodies to the GM2-1 islet ganglioside and to GAD-65 at type 1 diabetes onset. Journal of Autoimmunity. 10: 585-8. PMID 9451598 DOI: 10.1006/Jaut.1997.0166  0.512
1997 Ivarsson SA, Ackefors M, Carlsson A, Ekberg G, Falorni A, Kockum I, Landin-Olsson M, Lernmark A, Lindberg B, Sundkvist G, Svanberg L. Glutamate decarboxylase antibodies in non-diabetic pregnancy precedes insulin-dependent diabetes in the mother but not necessarily in the offspring. Autoimmunity. 26: 261-9. PMID 9543187 DOI: 10.3109/08916939709008032  0.494
1997 Örtqvist E, Falorni A, Scheynius A, Persson B, Lernmark Å. Age governs gender-dependent islet cell autoreactivity and predicts the clinical course in childhood IDDM Acta Paediatrica. 86: 1166-1171. PMID 9401507 DOI: 10.1111/J.1651-2227.1997.Tb14837.X  0.364
1997 Vandewalle CL, Falorni A, Lernmark A, Goubert P, Dorchy H, Coucke W, Semakula C, Van der Auwera B, Kaufman L, Schuit FC, Pipeleers DG, Gorus FK. Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry. Diabetes Care. 20: 1547-52. PMID 9314633 DOI: 10.2337/Diacare.20.10.1547  0.416
1997 Lotfi K, Sund G, Lowe R, Graham J, Landin-Olsson M, Kockum I, Deeb S, Lernmark A. The beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus Diabetologia. 40: 959-962. PMID 9267992 DOI: 10.1007/S001250050774  0.428
1997 Bieg S, Möller C, Olsson T, Lernmark Å. The lymphopenia (lyp) gene controls the intrathymic cytokine ratio in congenic biobreeding rats Diabetologia. 40: 786-792. PMID 9243099 DOI: 10.1007/S001250050750  0.313
1997 Gold DP, Shaikewitz ST, Mueller D, Redd JR, Sellins KS, Pettersson A, Lernmark A, Bellgrau D. T cells from BB-DP rats show a unique cytokine mRNA profile associated with the IDDM1 susceptibility gene, Lyp. Autoimmunity. 22: 149-61. PMID 8734569 DOI: 10.3109/08916939508995312  0.371
1996 Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ. Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401. The Journal of Clinical Investigation. 98: 2597-603. PMID 8958223 DOI: 10.1172/Jci119079  0.456
1996 Lernmark A. Glutamic acid decarboxylase--gene to antigen to disease. Journal of Internal Medicine. 240: 259-77. PMID 8946809 DOI: 10.1046/J.1365-2796.1996.27859000.X  0.364
1996 Agardh D, Gaur LK, Agardh E, Landin-Olsson M, Agardh C, Lernmark Å. HLA-DQB1*0201/0302 is associated with severe retinopathy in patients with IDDM Diabetologia. 39: 1313-1317. PMID 8932997 DOI: 10.1007/S001250050575  0.453
1996 Kobayashi T, Oka Y, Katagiri H, Falorni A, Kasuga A, Takei I, Nakanishi K, Murase T, Kosaka K, Lernmark Å. Association between HLA and islet cell antibodies in diabetic patients with a mitochondrial DNA mutation at base pair 3243 Diabetologia. 39: 1196-1200. PMID 8897007 DOI: 10.1007/Bf02658506  0.444
1996 Falorni A, Ackefors M, Carlberg C, Daniels T, Persson B, Robertson J, Lernmark A. Diagnostic sensitivity of immunodominant epitopes of glutamic acid decarboxylase (GAD65) autoantibodies in childhood IDDM. Diabetologia. 39: 1091-8. PMID 8877294 DOI: 10.1007/Bf00400659  0.323
1996 Kasuga A, Falorni A, Maruyama T, Ozawa Y, Grubin CE, Matsubara K, Takei I, Saruta T, Scheynius A, Lernmark Å. HLA class II is associated with the frequency of glutamic acid decarboxylase M(r) 65,000 autoantibodies in Japanese patients with insulin-dependent diabetes mellitus. Acta Diabetologica. 33: 108-113. PMID 8870811 DOI: 10.1007/Bf00569419  0.39
1996 Graham J, Kockum I, Breslow N, Lernmark Å, Holmberg E. A comparison of three statistical models for IDDM associations with HLA Tissue Antigens. 48: 1-14. PMID 8864169 DOI: 10.1111/J.1399-0039.1996.Tb02599.X  0.345
1996 Östman J, Lernmark Å, Landin-Olsson M, Sundkvist G, Palmer J, Arnqvist H, Blohmé G, Lithner F, Littorin B, Nyström L, Scherstén B, Wibell L. Autoimmune (type 1) diabetes in young adults in Sweden. Hormone and Metabolic Research. 28: 348-350. PMID 8858383 DOI: 10.1055/S-2007-979812  0.443
1996 Kockum I, Lernmark Å, Dahlquist G, Falorni A, Hagopian WA, Landin-Olsson M, Li LC, Luthman H, Palmer JP, Sanjeevi CB, Sundkvist G, Östman J. Genetic and immunological findings in patients with newly diagnosed insulin-dependent diabetes mellitus Hormone and Metabolic Research. 28: 344-347. PMID 8858382 DOI: 10.1055/S-2007-979811  0.413
1996 Kasuga A, Maruyama T, Ozawa Y, Takei I, Falorni A, Lernmark A, Saruta T. Antibody to the M(r) 65,000 isoform of glutamic acid decarboxylase are detected in non-insulin-dependent diabetes in Japanese. Journal of Autoimmunity. 9: 105-11. PMID 8845047 DOI: 10.1006/Jaut.1996.0013  0.414
1996 Sanjeevi CB, Höök P, Landin-Olsson M, Kockum I, Dahlquist G, Lybrand TP, Lernmark A. DR4 subtypes and their molecular properties in a population-based study of Swedish childhood diabetes. Tissue Antigens. 47: 275-83. PMID 8773316 DOI: 10.1111/J.1399-0039.1996.Tb02554.X  0.474
1996 Sanjeevi CB, Falorni A, Kockum I, Hagopian WA, Lernmark Å. HLA and glutamic acid decarboxylase in human insulin-dependent diabetes mellitus. Diabetic Medicine. 13: 209-217. PMID 8689840 DOI: 10.1002/(Sici)1096-9136(199603)13:3<209::Aid-Dia39>3.0.Co;2-2  0.453
1996 Tuomi T, Björses P, Falorni A, Partanen J, Perheentupa J, Lernmark Å, Miettinen A. Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I. The Journal of Clinical Endocrinology and Metabolism. 81: 1488-1494. PMID 8636356 DOI: 10.1210/Jcem.81.4.8636356  0.504
1996 Hallengren B, Falorni A, Landin-Olsson M, Lernmark Å, Papadopoulos KI, Sundkvist G. Islet cell and glutamic acid decarboxylase antibodies in hyperthyroid patients: at diagnosis and following treatment Journal of Internal Medicine. 239: 63-68. PMID 8551202 DOI: 10.1046/J.1365-2796.1996.417758000.X  0.399
1996 Sanjeevi C, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark Å. P831 - Combination of polymorphic residues in HLA-DQα and DQβ chains form a domain structure pattern and are associated with insulin-dependent diabetes (IDDM) Human Immunology. 47: 152. DOI: 10.1016/0198-8859(96)85526-1  0.437
1995 Kockum I, Sanjeevi CB, Eastman S, Landin-Olsson M, Dahlquist G, Lernmark A. Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish children with insulin-dependent diabetes and controls. European Journal of Immunogenetics : Official Journal of the British Society For Histocompatibility and Immunogenetics. 22: 443-65. PMID 8597561 DOI: 10.1111/J.1744-313X.1995.Tb00282.X  0.452
1995 Yu L, Chase HP, Falorni A, Rewers M, Lernmark Å, Eisenbarth GS. Sexual dimorphism in transmission of expression of islet autoantibodies to offspring Diabetologia. 38: 1353-1357. PMID 8582546 DOI: 10.1007/Bf00401769  0.501
1995 Li L, Jiang J, Hagopian WA, Karlsen AE, Skelly M, Baskin DG, Lernmark A. Differential detection of rat islet and brain glutamic acid decarboxylase (GAD) isoforms with sequence-specific peptide antibodies. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 43: 53-9. PMID 7822765 DOI: 10.1177/43.1.7822765  0.353
1995 Sanjeevi CB, Lybrand TP, DeWeese C, Landin-Olsson M, Kockum I, Dahlquist G, Sundkvist G, Stenger D, Lernmark A. Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM. Members of the Swedish Childhood Diabetes Study. Diabetes. 44: 125-31. PMID 7813806 DOI: 10.2337/Diab.44.1.125  0.453
1995 Sanjeevi CB, Landin-Olsson M, Kockum I, Dahlquist G, Lernmark Å. Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus Tissue Antigens. 45: 148-152. PMID 7792764 DOI: 10.1111/J.1399-0039.1995.Tb02434.X  0.411
1995 Lernmark A. Glutamic acid decarboxylase antibodies and diabetes complications. Assay reliability and validity. Diabetes Care. 18: 269-71. PMID 7729309 DOI: 10.2337/Diacare.18.2.269  0.425
1995 Hagopian WA, Sanjeevi CB, Kockum I, Landin-Olsson M, Karlsen AE, Sundkvist G, Dahlquist G, Palmer J, Lernmark Å. Glutamate decarboxylase-, insulin-, and islet cell-antibodies and HLA typing to detect diabetes in a general population-based study of Swedish children. Journal of Clinical Investigation. 95: 1505-1511. PMID 7706455 DOI: 10.1172/Jci117822  0.503
1995 Lernmark A, Klöppel G, Stenger D, Vathanaprida C, Fält K, Landin-Olsson M, Baskin DG, Palmer JP, Gown AM, Petersen JS. Heterogeneity of islet pathology in two infants with recent onset diabetes mellitus. Virchows Archiv : An International Journal of Pathology. 425: 631-40. PMID 7697219 DOI: 10.1007/Bf00199353  0.496
1995 Gottsäter A, Landin-Olsson M, Lernmark Å, Fernlund P, Sundkvist G, Hagopian WA. Glutamate decarboxylase antibody levels predict rate of β-cell decline in adult-onset diabetes Diabetes Research and Clinical Practice. 27: 133-140. PMID 7607051 DOI: 10.1016/0168-8227(95)01026-A  0.433
1995 Falorni A, Örtqvist E, Persson B, Lernmark Å. Radioimmunoassays for glutamic acid decarboxylase (GAD65) and GAD65 autoantibodies using 35S or 3H recombinant human ligands. Journal of Immunological Methods. 186: 89-99. PMID 7561152 DOI: 10.1016/0022-1759(95)00139-2  0.354
1995 Huang X, Yuang J, Goddard A, Foulis A, James RF, Lernmark A, Pujol-Borrell R, Rabinovitch A, Somoza N, Stewart TA. Interferon expression in the pancreases of patients with type I diabetes. Diabetes. 44: 658-64. PMID 7540571 DOI: 10.2337/Diab.44.6.658  0.397
1995 Pettersson A, Wilson D, Daniels T, Tobin S, Jacob HJ, Lander ES, Lernmark A. Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes. Journal of Autoimmunity. 8: 493-505. PMID 7492346 DOI: 10.1016/0896-8411(95)90004-7  0.491
1995 Sanjeevi CB, Kockum I, Lernmark Å. The role of the major histocompatibility complex in insulin-dependent diabetes mellitus Current Opinion in Endocrinology & Diabetes. 2: 3-11. DOI: 10.1097/00060793-199502000-00002  0.479
1994 Richardson RD, Ramsay DS, Lernmark A, Scheurink AJ, Baskin DG, Woods SC. Weight loss in rats following intraventricular transplants of pancreatic islets. The American Journal of Physiology. 266: R59-64. PMID 8304556 DOI: 10.1152/Ajpregu.1994.266.1.R59  0.306
1994 Sundkvist G, Hagopian WA, Landin-Olsson M, Lernmark Å, Ohlsson L, Ericsson C, Ahlmén J. Islet cell antibodies, but not glutamic acid decarboxylase antibodies, are decreased by plasmapheresis in patients with newly diagnosed insulin-dependent diabetes mellitus The Journal of Clinical Endocrinology and Metabolism. 78: 1159-1165. PMID 8175973 DOI: 10.1210/Jcem.78.5.8175973  0.464
1994 Buesa-Gomez J, de la Torre JC, Dyrberg T, Landin-Olsson M, Mauseth RS, Lernmark A, Oldstone MB. Failure to detect genomic viral sequences in pancreatic tissues from two children with acute-onset diabetes mellitus. Journal of Medical Virology. 42: 193-7. PMID 8158114 DOI: 10.1002/Jmv.1890420217  0.366
1994 Grubin CE, Daniels T, Toivola B, Landin-Olsson M, Hagopian WA, Li L, Karlsen AE, Boel E, Michelsen B, Lernmark A. A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetologia. 37: 344-50. PMID 8063033 DOI: 10.1007/Bf00408469  0.369
1994 Gottsäter A, Landin-Olsson M, Lernmark Å, Fernlund P, Sundkvist G. Islet cell antibodies are associated with β -cell failure also in obese adult onset diabetic patients Acta Diabetologica. 31: 226-231. PMID 7888694 DOI: 10.1007/Bf00571956  0.35
1994 Kockum I, Wassmuth R, Holmberg E, Michelsen B, Lernmark Å. Inheritance of MHC class II genes in IDDM studied in population-based affected and control families Diabetologia. 37: 1105-1112. PMID 7867882 DOI: 10.1007/Bf00418374  0.353
1994 Lernmark Å. Molecular biology of IDDM. Diabetologia. 37. PMID 7821743 DOI: 10.1007/Bf00400829  0.508
1994 Sanjeevi CB, Lybrand TP, Landin-Olsson M, Kockum I, Dahlquist G, Hagopian WA, Palmer JP, Lernmark A. Analysis of antibody markers, DRB1, DRB5, DQA1 and DQB1 genes and modeling of DR2 molecules in DR2-positive patients with insulin-dependent diabetes mellitus. Tissue Antigens. 44: 110-9. PMID 7817375 DOI: 10.1111/J.1399-0039.1994.Tb02366.X  0.447
1994 Hao W, Li L, Mehta V, Lernmark Å, Palmer JP. Functional state of the β cell affects expression of both forms of glutamic acid decarboxylase Pancreas. 9: 558-562. PMID 7809009 DOI: 10.1097/00006676-199409000-00003  0.409
1994 Falorni A, Grubin CE, Takei I, Shimada A, Kasuga A, Maruyama T, Ozawa Y, Kasatani T, Saruta T, Li L, Lernmark A. Radioimmunoassay Detects the Frequent Occurrence of Autoantibodies to the Mr 65,000 Isoform of Glutamic Acid Decarboxylase in Japanese Insulin-Dependent Diabetes Autoimmunity. 19: 113-125. PMID 7772701 DOI: 10.3109/08916939409009539  0.524
1994 Jacob HJ, Pettersson A, Wilson D, Mao Y, Lernmark Å, Lander ES. Erratum: Corrigendum: Genetic dissection of autoimmune type I diabetes in the BB rat Nature Genetics. 7: 215-215. DOI: 10.1038/Ng0694-215A  0.451
1993 Hagopian WA, Karlsen AE, Petersen JS, Teague J, Gervassi A, Jiang J, Fujimoto W, Lernmark A. Regulation of glutamic acid decarboxylase diabetes autoantigen expression in highly purified isolated islets from Macaca nemestrina Endocrinology. 132: 2674-2681. PMID 8504767 DOI: 10.1210/Endo.132.6.8504767  0.383
1993 Neifing JL, Greenbaum CJ, Kahn SE, McCulloch DK, Barmeier H, Lernmark Å, Palmer JP. Prospective evaluation of β-cell function in insulin antoantibody-positive relatives of insulin-dependent diabetic patients☆ Metabolism-Clinical and Experimental. 42: 482-486. PMID 8487672 DOI: 10.1016/0026-0495(93)90107-Y  0.4
1993 Hagopian WA, Michelsen B, Karlsen AE, Larsen F, Moody A, Grubin CE, Rowe R, Petersen J, McEvoy R, Lernmark A. Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase. Diabetes. 42: 631-6. PMID 8454115 DOI: 10.2337/Diab.42.4.631  0.35
1993 Ivarsson S-, Eriksson S, Kockum I, Lernmark Å, Lindgren S, Nilsson KO, Sundkvist G, Wassmuth R. HLA-DR3, DQ2 homozygosity in two patients with insulin-dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis. Journal of Internal Medicine. 233: 281-286. PMID 8450297 DOI: 10.1111/J.1365-2796.1993.Tb00988.X  0.504
1993 Petersen JS, Russel S, Marshall MO, Kofod H, Buschard K, Cambon N, Karlsen AE, Boel E, Hagopian WA, Hejnæs KR, Moody A, Dyrberg T, Lernmark A, Madsen OD, Michelsen BK. Differential expression of glutamic acid decarboxylase in rat and human islets Diabetes. 42: 484-495. PMID 8432419 DOI: 10.2337/Diab.42.3.484  0.366
1993 Hagopian WA, Karlsen AE, Gottsäter A, Landin-Olsson M, Grubin CE, Sundkvist G, Petersen JS, Boel E, Dyrberg T, Lernmark A. Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type Journal of Clinical Investigation. 91: 368-374. PMID 8423232 DOI: 10.1172/Jci116195  0.515
1993 Lernmark Å, Möller C, Kockum I, Sanjeevi C. Autoimmune endocrinopathies 3 Islet cell autoimmunity Journal of Internal Medicine. 234: 361-369. PMID 8409832 DOI: 10.1111/J.1365-2796.1993.Tb00757.X  0.356
1993 Gottsäter A, Landin-Olsson M, Fernlund P, Lernmark Å, Sundkvist G. β-Cell Function in Relation to Islet Cell Antibodies During the First 3 Yr After Clinical Diagnosis of Diabetes in Type II Diabetic Patients Diabetes Care. 16: 902-910. PMID 8325204 DOI: 10.2337/Diacare.16.6.902  0.439
1993 Markholst H, Eastman S, Wilson D, Fisher L, Lernmark A. Decreased weight gain in BB rats before the clinical onset of insulin-dependent diabetes. Diabetes Research and Clinical Practice. 21: 31-8. PMID 8253019 DOI: 10.1016/0168-8227(93)90094-L  0.433
1993 Jobe LW, Ubungen R, Goodner CJ, Baskin DG, Braquet P, Lernmark A. Protection from BB rat diabetes by the platelet-activating factor inhibitor BN50730. Autoimmunity. 16: 259-66. PMID 8025205 DOI: 10.3109/08916939309014644  0.416
1993 Jacob HJ, Pettersson A, Wilson D, Mao Y, Lernmark A, Lander ES. Genetic dissection of autoimmune type I diabetes in the BB rat. Nature Genetics. 2: 56-60. PMID 1303251 DOI: 10.1038/Ng0992-56  0.441
1993 Sanjeevi CB, Zeidler A, Shaw S, Rotter J, Nepom GT, Costin G, Raffel L, Eastman S, Kockum I, Wassmuth R, Lernmark Å. Analysis of HLA-DQA1 and -DQB1 genes in Mexican Americans with insulin-dependent diabetes mellitus Tissue Antigens. 42: 72-77. DOI: 10.1111/J.1399-0039.1993.Tb02170.X  0.44
1993 Pettersson A, Sjöberg K, Lernmark Å, Eriksson S. HLA genotypes in coeliac disease and healthy individuals carrying gliadin antibodies European Journal of Gastroenterology & Hepatology. 5: 445-450. DOI: 10.1097/00042737-199306000-00009  0.339
1992 Sundkvist G, Bergqvist A, Weibull H, Bergqvist D, Fält K, Olsson ML, Lernmark A. Islet cell antibody reactivity with human fetal pancreatic islets. Diabetes Research and Clinical Practice. 14: 1-7. PMID 1748059 DOI: 10.1016/0168-8227(91)90046-G  0.425
1992 Landin-Olsson M, Karlsson FA, Lernmark A, Sundkvist G. Islet cell and thyrogastric antibodies in 633 consecutive 15- to 34-yr-old patients in the diabetes incidence study in Sweden. Diabetes. 41: 1022-1027. PMID 1628762 DOI: 10.2337/Diab.41.8.1022  0.471
1992 Jobe LW, Vertrees S, Wilson CA, Jacobs C, Wilson DL, Picha KS, Baker P, Lernmark A. In vivo effects of interleukin-1 beta on blood leukocytes in BB rats prone or resistant to diabetes. Autoimmunity. 11: 233-7. PMID 1581467 DOI: 10.3109/08916939209035160  0.335
1992 Lernmark A, Morris PJ, Rubenstein AH. Diabetes and frontiers of research. Introduction. Diabetologia. 35: A9-11. PMID 1478374 DOI: 10.1007/Bf00586272  0.446
1992 Lernmark A. Immune intervention yes, but for what reason, for whom, when and how ? Diabetologia. 35: 1096-1098. PMID 1473622 DOI: 10.1007/Bf02221688  0.489
1992 Bärmeier H, Ahlmén J, Landin-olsson M, Rajotte RV, Sundkvist G, Warnock G, Lernmark Å. Quantitative analysis of islet glutamic acid decarboxylase p64 autoantibodies in insulin-dependent diabetes mellitus. Autoimmunity. 13: 187-196. PMID 1472630 DOI: 10.3109/08916939209004823  0.449
1992 Gottsäter A, Landin-Olsson M, Fernlund P, Gullberg B, Lernmark Å, Sundkvist G. Pancreatic beta-cell function evaluated by intravenous glucose and glucagon stimulation. A comparison between insulin and C-peptide to measure insulin secretion Scandinavian Journal of Clinical & Laboratory Investigation. 52: 631-639. PMID 1455155 DOI: 10.3109/00365519209115506  0.313
1992 Greenbaum CJ, Palmer JP, Nagataki S, Yamaguchi Y, Molenaar JL, Van Beers WA, MacLaren NK, Lernmark A. Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop. Diabetes. 41: 1570-4. PMID 1446798 DOI: 10.2337/Diab.41.12.1570  0.373
1992 Karlsen AE, Hagopian WA, Petersen JS, Boel E, Dyrberg T, Grubin CE, Michelsen BK, Madsen OD, Lernmark A. Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies. Diabetes. 41: 1355-9. PMID 1397711 DOI: 10.2337/Diab.41.10.1355  0.348
1991 Herold KC, Kastern W, Markholst H, Lernmark A. Derivation of non-lymphopenic BB rats with an intercross breeding. Autoimmunity. 3: 83-93. PMID 2577492 DOI: 10.3109/08916938909019957  0.506
1991 Markholst H, Eastman S, Wilson D, Andreasen BE, Lernmark A. Diabetes segregates as a single locus in crosses between inbred BB rats prone or resistant to diabetes. The Journal of Experimental Medicine. 174: 297-300. PMID 2056281 DOI: 10.1084/Jem.174.1.297  0.492
1991 Lernmark Å. Human cell lines from families available for diabetes research Diabetologia. 34: 61-61. PMID 2055345 DOI: 10.1007/Bf00404029  0.401
1991 Bärmeier H, McCulloch DK, Neifing JL, Warnock G, Rajotte RV, Palmer JP, Lernmark Å. Risk for developing type 1 (insulin-dependent) diabetes mellitus and the presence of islet 64K antibodies. Diabetologia. 34: 727-733. PMID 1959705 DOI: 10.1007/Bf00401518  0.493
1991 Karlsen AE, Hagopian WA, Grubin CE, Dube S, Disteche CM, Adler DA, Bärmeier H, Mathewes S, Grant FJ, Foster D, Lernmark A. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10 Proceedings of the National Academy of Sciences of the United States of America. 88: 8337-8341. PMID 1924293 DOI: 10.1073/Pnas.88.19.8337  0.358
1991 Lernmark Å, Molenaar JL, Beers WAMv, Yamaguchi Y, Nagataki S, Ludvigsson J, Maclaren NK, Arnaiz-Villena A, Barbosa J, deBeaufort C, Becker D, Becker F, Betterle C, Bosi E, Bottazzo GF, et al. The Fourth International Serum Exchange Workshop to standardize cytoplasmic islet cell antibodies Diabetologia. 34: 534-535. PMID 1916061 DOI: 10.1007/Bf00403293  0.317
1991 Eastman S, Markholst H, Wilson D, Lernmark A. Leukocytosis at the onset of diabetes in crosses of inbred BB rats. Diabetes Research and Clinical Practice. 12: 113-23. PMID 1879302 DOI: 10.1016/0168-8227(91)90088-U  0.47
1991 Marner B, Bille G, Christy M, Damsgaard EM, Garne S, Heinze E, Larsen S, Lernmark A, Mandrup-Poulsen T, Nerup J. Islet cell cytoplasmic antibodies (ICA) in diabetes and disorders of glucose tolerance. Diabetic Medicine : a Journal of the British Diabetic Association. 8: 812-6. PMID 1837507 DOI: 10.1111/J.1464-5491.1991.Tb02118.X  0.526
1991 Vertrees S, Wilson CA, Ubungen R, Wilson D, Baskin DG, Toivola B, Jacobs C, Boiani N, Baker P, Lernmark A. Interleukin-1 beta regulation of islet and thyroid autoimmunity in the BB rat. Journal of Autoimmunity. 4: 717-32. PMID 1797022 DOI: 10.1016/0896-8411(91)90168-C  0.394
1991 Beck JC, Goodner CJ, Wilson C, Wilson D, Glidden D, Baskin DG, Lernmark A, Braquet P. Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat. Autoimmunity. 9: 225-35. PMID 1777555 DOI: 10.3109/08916939109007648  0.433
1991 Sairenji T, Daibata M, Sorli CH, Qvistbäck H, Humphreys RE, Ludvigsson J, Palmer J, Landin-Olsson M, Sundkvist G, Michelsen B, Lernmark Å, Dyrberg T. Relating homology between the Epstein-Barr virus BOLF1 molecule and HLA-DQw8 β chain to recent onset Type 1 (insulin-dependent) diabetes mellitus Diabetologia. 34: 33-39. PMID 1647336 DOI: 10.1007/Bf00404022  0.413
1991 Lernmark å, Bärmeier H, Dube S, Hagopian W, Karlsen A, Wassmuth R. Autoimmunity of diabetes. Endocrinology and Metabolism Clinics of North America. 20: 589-617. DOI: 10.1016/S0889-8529(18)30260-3  0.468
1990 Michelsen B, Wassmuth R, Ludvigsson J, Lernmark A, Nepom GT, Fisher L. HLA heterozygosity in insulin-dependent diabetes is most frequent at the DQ locus. Scandinavian Journal of Immunology. 31: 405-13. PMID 2333466 DOI: 10.1111/J.1365-3083.1990.Tb02786.X  0.433
1990 Landin-Olsson M, Nilsson KO, Lernmark Å, Sundkvist G. Islet cell antibodies and fasting C-peptide predict insulin requirement at diagnosis of diabetes mellitus. Diabetologia. 33: 561-568. PMID 2253834 DOI: 10.1007/Bf00404145  0.477
1990 Markholst H, Klaff LJ, Klöppel G, Lernmark A, Mordes JP, Palmer J. Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats. Diabetes. 39: 720-7. PMID 2189763 DOI: 10.2337/Diab.39.6.720  0.465
1990 Landin-Olsson M, Borgstrom Å, Blom L, Sundkvist G, Lernmark A, Nyström L, Sandström A, Wall S, Aili M, Bäckman H, Carlsson E, Edenwall H, Elfstrand PO, Granström BW, Gustavsson I, et al. Immunoreactive trypsin(Ogen) in the sera of children with recent-onset insulin-dependent diabetes and matched controls Pancreas. 5: 241-247. PMID 2188253 DOI: 10.1097/00006676-199005000-00001  0.495
1990 Michelsen B, Dyrberg T, Vissing H, Serup P, Lernmark A. HLA-DQ and -DX genes in insulin-dependent diabetes mellitus Current Topics in Microbiology and Immunology. 164: 57-68. PMID 2127393 DOI: 10.1007/978-3-642-75741-9_4  0.501
1990 Bonifacio E, Boitard C, Gleichmann H, Shattock MA, Molenaar JL, Bottazzo GF, Assa S, Arnaiz-Villena A, Barbosa J, Betterle C, Beutner E, Bright G, Chapel H, Codina M, Dawkins R, et al. Assessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays Diabetologia. 33: 731-736. PMID 2073986 DOI: 10.1007/Bf00400345  0.355
1989 Wassmuth R, Lernmark Å. The genetics of susceptibility to diabetes Clinical Immunology and Immunopathology. 53: 358-399. PMID 2680191 DOI: 10.1016/0090-1229(89)90002-0  0.35
1989 Löhr M, Markholst H, Dyrberg T, Klöppel G, Oberholzer M, Lernmark Å. Insulitis and Diabetes are Preceded by a Decrease in p Cell Volume in Diabetes-prone BB Rats Pancreas. 4: 95-100. PMID 2654931 DOI: 10.1097/00006676-198902000-00015  0.465
1989 Bonnevie-Nielsen V, Larsen ML, Frifelt JJ, Michelsen B, Lernmark A. Association of IDDM and attenuated response of 2',5'-oligoadenylate synthetase to yellow fever vaccine Diabetes. 38: 1636-1642. PMID 2573556 DOI: 10.2337/Diab.38.12.1636  0.306
1989 Landin-Olsson M, Karlsson A, Dahlquist G, Blom L, Lernmark Å, Sundkvist G. Islet cell and other organ-specific autoantibodies in all children developing type 1 (insulin-dependent) diabetes mellitus in Sweden during one year and in matched control children. Diabetologia. 32: 387-395. PMID 2547682 DOI: 10.1007/Bf00277264  0.479
1988 Wogensen LD, Mandrup-Poulsen T, Markholst H, Mølvig J, Lernmark A, Holst JJ, Dinarello CA, Nerup J. Interleukin-1 potentiates glucose stimulated insulin release in the isolated perfused pancreas. Acta Endocrinologica. 117: 302-6. PMID 3289298 DOI: 10.1530/Acta.0.1170302  0.32
1988 Markholst H, Lernmark Å. Reduced pancreatic insulin is associated with retarded growth of the pancreas in young prediabetic BB rats. Pancreas. 3: 140-144. PMID 3287368 DOI: 10.1097/00006676-198804000-00005  0.461
1988 Kofod H, Holst JJ, Lernmark Å. Secretion uncouples glucose inhibition of glucagon-producing cells resulting in a simultaneous stimulation of both glucagon and insulin release Regulatory Peptides. 23: 315-322. PMID 3070646 DOI: 10.1016/0167-0115(88)90232-7  0.309
1988 Wallensteen M, Dahlquist G, Persson B, Landin-Olsson M, Lernmark Å, Sundkvist G, Thalme B. Factors influencing the magnitude, duration, and rate of fall of B-cell function in Type 1 (insulin-dependent) diabetic children followed for two years from their clinical diagnosis Diabetologia. 31: 664-669. PMID 3069534 DOI: 10.1007/Bf00278749  0.386
1988 Christie M, Landin-Olsson M, Sundkvist G, Dahlquist G, Lernmark A, Baekkeskov S. Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes Diabetologia. 31: 597-602. PMID 3065114 DOI: 10.1007/Bf00264766  0.489
1988 Matsuba I, Lernmark Å, Michelsen B, Nielsen JH, Scholler J, Vissing H, Welinder B, Tommerup N, Mikkelsen M, Ishikawa H, Ikeda Y, Tanese T. Gene probes to detect cross-culture contamination in hormone producing cell lines. In Vitro Cellular & Developmental Biology – Plant. 24: 1071-1076. PMID 2903855 DOI: 10.1007/Bf02620807  0.316
1988 Madsen OD, Andersen LC, Michelsen B, Owerbach D, Larsson LI, Lernmark A, Steiner DF. Tissue-specific expression of transfected human insulin genes in pluripotent clonal rat insulinoma lines induced during passage in vivo. Proceedings of the National Academy of Sciences of the United States of America. 85: 6652-6. PMID 2842785 DOI: 10.1073/Pnas.85.18.6652  0.351
1988 Kofod H, Andreu D, Thams P, Merrifield RB, Hedeskov CJ, Hansen B, Lernmark A. Insulin release by glucagon and secretin: studies with secretin-glucagon hybrids. The American Journal of Physiology. 254: E454-8. PMID 2833112 DOI: 10.1152/Ajpendo.1988.254.4.E454  0.32
1988 Ivarsson SA, Marner B, Lernmark A, Nilsson KO. Nonislet pancreatic autoantibodies in sibship with permanent neonatal insulin-dependent diabetes mellitus. Diabetes. 37: 347-50. PMID 2453387 DOI: 10.2337/Diab.37.3.347  0.542
1987 Contreas G, Madsen OD, Vissing H, Lernmark A. A simple assay for the detection of antibodies to endocrine islet cell surface antigens. Journal of Immunological Methods. 95: 135-9. PMID 3537136 DOI: 10.1016/0022-1759(86)90328-5  0.403
1987 Pipeleers D, Van de Winkel M, Dyrberg T, Lernmark A. Spontaneously diabetic BB rats have age-dependent islet beta-cell-specific surface antibodies at clinical onset. Diabetes. 36: 1111-5. PMID 3308581 DOI: 10.2337/Diab.36.10.1111  0.493
1987 Olsson ML, Sundkvist G, Lernmark A. Prolonged incubation in the two-colour immunofluorescence test increases the prevalence and titres of islet cell antibodies in type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 30: 327-32. PMID 3301483 DOI: 10.1007/Bf00299026  0.537
1987 Lernmark A. Islet cell antibodies. Diabetic Medicine. 4: 285-292. PMID 2956036 DOI: 10.1111/J.1464-5491.1987.Tb00881.X  0.497
1987 Michelsen B, Lernmark A. Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ. The Journal of Clinical Investigation. 79: 1144-52. PMID 2881947 DOI: 10.1172/Jci112931  0.419
1987 Madsen OD, Larsson LI, Rehfeld JF, Schwartz TW, Lernmark A, Labrecque AD, Steiner DF. Cloned cell lines from a transplantable islet cell tumor are heterogeneous and express cholecystokinin in addition to islet hormones. The Journal of Cell Biology. 103: 2025-34. PMID 2877997 DOI: 10.1083/Jcb.103.5.2025  0.315
1987 Michelsen B, Bækkeskov S, Herold B, Christie M, Lernmark Å. Autoimmune Aspects of Insulin-Dependent Diabetes Mellitus Journal of the Japan Diabetes Society. 30: 1077-1085. DOI: 10.11213/Tonyobyo1958.30.1077  0.502
1987 Bonifacio E, Dawkins RL, Lernmark Å. Immunology and Diabetes Workshops: Report of the Second International Workshop on the Standardisation of Cytoplasmic Islet Cell Antibodies: Summary of a Workshop organised by the Immunology and Diabetes Workshops Committee, supported in part by the Juvenile Diabetes Foundation International, and held at the ?Science at Sea ? 1987? meeting in Perth, Western Australia, from 20?22 January 1987 Diabetologia. 30: 273-273. DOI: 10.1007/Bf00270427  0.502
1986 Svenningsen A, Dyrberg T, Markholst H, Binder C, Lernmark A. Insulin release and pancreatic insulin is reduced in young prediabetic BB rats. Acta Endocrinologica. 112: 367-71. PMID 3529783 DOI: 10.1530/Acta.0.1120367  0.418
1986 Vissing H, Papadopoulos G, Lernmark A. Monoclonal antibodies against pancreatic islet-cell-surface antigens selected by flow cytofluorometry. Scandinavian Journal of Immunology. 23: 425-33. PMID 3518043 DOI: 10.1111/J.1365-3083.1986.Tb03074.X  0.366
1986 Bonnevie-Nielsen V, Lernmark A. An H-2 alloantiserum preserves beta-cell function in mice made diabetic by low-dose streptozocin. Diabetes. 35: 570-3. PMID 3514332 DOI: 10.2337/Diab.35.5.570  0.323
1986 Kofod H, Hansen B, Lernmark A, Hedeskov CJ. Secretin and its C-terminal hexapeptide potentiates insulin release in mouse islets. The American Journal of Physiology. 250: E107-13. PMID 3513606 DOI: 10.1152/Ajpendo.1986.250.2.E107  0.314
1986 Hägglöf B, Rabinovitch A, Mackay P, Huen A, Rubenstein AH, Marner B, Nerup J, Lernmark A. Islet cell and other organ-specific autoantibodies in healthy first-degree relatives to insulin-dependent. Acta Paediatrica Scandinavica. 75: 611-8. PMID 3489346 DOI: 10.1111/J.1651-2227.1986.Tb10260.X  0.467
1986 Björck L, Kryspin-Sörensen I, Dyrberg T, Lernmark A, Kastern W. A deletion in a rat major histocompatibility complex class I gene is linked to the absence of beta 2-microglobulin-containing serum molecules. Proceedings of the National Academy of Sciences of the United States of America. 83: 5630-3. PMID 3016711 DOI: 10.1073/Pnas.83.15.5630  0.31
1986 Bakkeskov S, Bruining J, Srikanta S, Mandrup T, Beaufort C, Eisenbarth G, Nerup J, Lernmark Å. Antibodies to an Mr 64,000 Human Islet Cell Protein in the Prediabetic Period of IDDM Patients Annals of the New York Academy of Sciences. 475: 415-417. DOI: 10.1111/J.1749-6632.1986.Tb20913.X  0.327
1985 Lernmark A, Baekkeskov S, Gerling I, Kastern W, Knutson C, Michelsen B. Immunological aspects of type 1 and 2 diabetes mellitus. Advances in Experimental Medicine and Biology. 189: 107-27. PMID 4036712 DOI: 10.1007/978-1-4757-1850-8_7  0.413
1985 Marner B, Agner T, Binder C, Lernmark Å, Nerup J, Mandrup-Poulsen T, Walldorff S. Increased reduction in fasting C-peptide is associated with islet cell antibodies in Type 1 (insulin-dependent) diabetic patients Diabetologia. 28: 875-880. PMID 3912242 DOI: 10.1007/Bf00703129  0.451
1985 Dyrberg T, King J, Lernmark A, Martin JM. Cortisone fails to affect levels of islet cell surface antibodies and incidence of diabetes in the BB rat. Endocrinology. 116: 47-50. PMID 3880546 DOI: 10.1210/Endo-116-1-47  0.519
1985 Lernmark A. Molecular biology of type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 28: 195-203. PMID 3160627 DOI: 10.1007/Bf00282232  0.493
1985 Deufel T, Grove A, Kofod H, Lernmark A. Locus-specific detection of HLA-DQ and -DR antigens by antibodies against synthetic N-terminal octapeptides of the beta chain. Febs Letters. 189: 329-37. PMID 2995123 DOI: 10.1016/0014-5793(85)81050-4  0.313
1984 Baekkeskov S, Dyrberg T, Lernmark A. Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science (New York, N.Y.). 224: 1348-50. PMID 6374896 DOI: 10.1126/Science.6374896  0.362
1984 Papadopoulos G, Petersen J, Andersen V, Lernmark A, Marner B, Nerup J, Binder C. Spontaneous in vitro immunoglobulin secretion at the diagnosis of insulin-dependent diabetes. Acta Endocrinologica. 105: 521-7. PMID 6372349 DOI: 10.1530/Acta.0.1050521  0.458
1984 Dyrberg T, Poussier P, Nakhooda F, Marliss EB, Lernmark Å. Islet cell surface and lymphocyte antibodies often precede the spontaneous diabetes in the BB rat Diabetologia. 26: 159-165. PMID 6370763 DOI: 10.1007/Bf00281126  0.471
1984 Rabinovitch A, MacKay P, Ludvigsson J, Lernmark A. A prospective analysis of islet-cell cytotoxic antibodies in insulin-dependent diabetic children. Transient effects of plasmapheresis. Diabetes. 33: 224-8. PMID 6365659 DOI: 10.2337/Diab.33.3.224  0.408
1984 Scott J, MacKay PG, Lernmark A. In vitro lymphocyte recognition of islet cells following in vivo priming with allogeneic murine pancreatic islets. Acta Endocrinologica. 105: 87-92. PMID 6229965 DOI: 10.1530/Acta.0.1050087  0.367
1984 Owerbach D, Hägglöf B, Lernmark A, Holmgren G. Susceptibility to insulin-dependent diabetes defined by restriction enzyme polymorphism of HLA-D region genomic DNA. Diabetes. 33: 958-65. PMID 6090247 DOI: 10.2337/Diab.33.10.958  0.438
1983 Dyrberg T, Nakhooda AF, Baekkeskov S, Lernmark A, Poussier P, Marliss EB. Islet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat. Diabetes. 31: 278-81. PMID 6759244 DOI: 10.2337/Diab.31.3.278  0.448
1983 Brogren CH, Lernmark A. Islet cell antibodies in diabetes. Clinics in Endocrinology and Metabolism. 11: 409-30. PMID 6754163 DOI: 10.1016/S0300-595X(82)80022-4  0.396
1983 Ludvigsson J, Heding L, Liedén G, Marner B, Lernmark A. Plasmapheresis in the initial treatment of insulin-dependent diabetes mellitus in children. British Medical Journal (Clinical Research Ed.). 286: 176-8. PMID 6401518 DOI: 10.1136/Bmj.286.6360.176  0.477
1983 Svenningsen A, Dyrberg T, Gerling I, Lernmark A, Mackay P, Rabinovitch A. Inhibition of insulin release after passive transfer of immunoglobulin from insulin-dependent diabetic children to mice. The Journal of Clinical Endocrinology and Metabolism. 57: 1301-4. PMID 6355141 DOI: 10.1210/Jcem-57-6-1301  0.462
1983 Marner B, Lernmark Å, Nerup J, Molenaar JL, Tuk CW, Bruining GJ. Analysis of islet cell antibodies on frozen sections of human pancreas. Diabetologia. 25: 93-96. PMID 6354815 DOI: 10.1007/Bf00250895  0.337
1983 Kanatsuna T, Baekkeskov S, Lernmark A, Ludvigsson J. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release. Diabetes. 32: 520-4. PMID 6354781 DOI: 10.2337/Diab.32.6.520  0.453
1983 Dyrberg T, Poussier P, Nakhooda AF, Marliss EB, Lernmark A. Humoral immunity in the spontaneously diabetic BB rat. Metabolism: Clinical and Experimental. 32: 87-91. PMID 6345998 DOI: 10.1016/S0026-0495(83)80018-3  0.505
1983 Nordén G, Jensen E, Stilbo I, Bottazzo GF, Lernmark A. B-cell function and islet cell and other organ-specific autoantibodies in relatives to insulin-dependent diabetic patients. Acta Medica Scandinavica. 213: 199-203. PMID 6342336 DOI: 10.1111/J.0954-6820.1983.Tb03717.X  0.505
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