Karnam S. Murthy - Publications

Affiliations: 
Physiology Virginia Commonwealth University, Richmond, VA, United States 
Area:
Physiology Biology, Molecular Biology

174 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Singh K, Randhwa G, Salloum FN, Grider JR, Murthy KS. Decreased smooth muscle function, peristaltic activity, and gastrointestinal transit in dystrophic (mdx) mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13968. PMID 32789934 DOI: 10.1111/Nmo.13968  0.511
2019 Crowe MS, Wang H, Blakeney BA, Mahavadi S, Singh K, Murthy KS, Grider JR. Expression and function of umami receptors T1R1/T1R3 in gastric smooth muscle. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13737. PMID 31721379 DOI: 10.1111/Nmo.13737  0.447
2019 Wang H, Murthy KS, Grider JR. Expression patterns of L-amino acid receptors in the murine STC-1 enteroendocrine cell line. Cell and Tissue Research. PMID 31410629 DOI: 10.1007/S00441-019-03074-Y  0.347
2019 Randhawa G, Singh K, Mahavadi S, Cain C, Salloum FN, Murthy KS, Grider JR. Hydrogen Sulfide Improves Aberrant Gastric Smooth Muscle Function in Duchenne Muscular Dystrophy Mice The Faseb Journal. DOI: 10.25772/Sytj-Tq93  0.454
2018 Mahavadi S, Nalli AD, Wang H, Kendig DM, Crowe MS, Lyall V, Grider JR, Murthy KS. Regulation of gastric smooth muscle contraction via Ca2+-dependent and Ca2+-independent actin polymerization. Plos One. 13: e0209359. PMID 30571746 DOI: 10.1371/Journal.Pone.0209359  0.57
2018 Blakeney BA, Crowe MS, Mahavadi S, Murthy KS, Grider JR. Branched Short-Chain Fatty Acid Isovaleric Acid Causes Colonic Smooth Muscle Relaxation via cAMP/PKA Pathway. Digestive Diseases and Sciences. PMID 30560338 DOI: 10.1007/S10620-018-5417-5  0.339
2018 May AT, Crowe MS, Blakeney BA, Mahavadi S, Wang H, Grider JR, Murthy KS. Identification of expression and function of the glucagon-like peptide-1 receptor in colonic smooth muscle. Peptides. 112: 48-55. PMID 30508636 DOI: 10.1016/J.Peptides.2018.11.007  0.577
2018 Mahavadi S, Grider JR, Murthy KS. Muscarinic m2 receptor-mediated actin polymerization via PI3 kinase γ and integrin-linked kinase in gastric smooth muscle. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13495. PMID 30393912 DOI: 10.1111/Nmo.13495  0.552
2018 Crowe MS, Mahavadi S, Blakeney BA, Murthy KS, Grider JR. Su1667 - Expression and Function of Umami (T1R1/T1R3) and Sweet (T1R2/T1R3) Nutrient Receptors in Mouse Gastric Smooth Muscle Gastroenterology. 154: S-568. DOI: 10.1016/S0016-5085(18)32089-4  0.479
2018 Blakeney BA, Crowe MS, Mahavadi S, Murthy KS, Grider JR. Su1203 - Effect of the Branched Chain Fatty Acid Isovaleric Acid (IVA) on Smooth Muscle Contractility and Colonic Peristalsis Gastroenterology. 154: S-502. DOI: 10.1016/S0016-5085(18)31903-6  0.387
2017 Nalli AD, Wang H, Bhattacharya S, Blakeney BA, Murthy KS. Inhibition of RhoA/Rho kinase pathway and smooth muscle contraction by hydrogen sulfide. Pharmacology Research & Perspectives. 5. PMID 28971603 DOI: 10.1002/Prp2.343  0.794
2017 Nalli AD, Bhattacharya S, Wang H, Kendig DM, Grider JR, Murthy KS. Augmentation of cGMP/PKG Pathway and Colonic Motility by Hydrogen Sulfide. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00161.2017. PMID 28705807 DOI: 10.1152/Ajpgi.00161.2017  0.75
2017 Mahavadi S, Sriwai W, Manion O, Grider JR, Murthy KS. Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle. Plos One. 12: e0178574. PMID 28678840 DOI: 10.1371/Journal.Pone.0178574  0.475
2017 Qian J, Mummalaneni S, Phan TT, Heck GL, DeSimone JA, West D, Mahavadi S, Hojati D, Murthy KS, Rhyu MR, Spielman AI, Özdener MH, Lyall V. Cyclic-AMP regulates postnatal development of neural and behavioral responses to NaCl in rats. Plos One. 12: e0171335. PMID 28192441 DOI: 10.1371/Journal.Pone.0171335  0.31
2016 Qian J, Mummalaneni SK, Alkahtani RM, Mahavadi S, Murthy KS, Grider JR, Lyall V. Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells. Plos One. 11: e0166565. PMID 27846263 DOI: 10.1371/Journal.Pone.0166565  0.324
2016 Zhang Y, Li F, Xiao X, Deng W, Yin C, Zhang T, Murthy KS, Hu W. Regulator of G protein signaling 4 is a novel target of GATA-6 transcription factor. Biochemical and Biophysical Research Communications. PMID 27746176 DOI: 10.1016/J.Bbrc.2016.10.024  0.391
2016 Zhang Y, Li F, Wang H, Yin C, Huang J, Mahavadi S, Murthy KS, Hu W. Immune/Inflammatory Response and Hypocontractility of Rabbit Colonic Smooth Muscle After TNBS-Induced Colitis. Digestive Diseases and Sciences. PMID 26879904 DOI: 10.1007/S10620-016-4078-5  0.479
2015 Al-Qudah M, Alkahtani R, Akbarali HI, Murthy KS, Grider JR. Stimulation of synthesis and release of brain-derived neurotropic factor from intestinal smooth muscle cells by substance P and pituitary adenylate cyclase-activating peptide. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 27: 1162-74. PMID 26088546 DOI: 10.1111/Nmo.12604  0.405
2015 Li C, Iness A, Yoon J, Grider JR, Murthy KS, Kellum JM, Kuemmerle JF. Noncanonical STAT3 activation regulates excess TGF-β1 and collagen I expression in muscle of stricturing Crohn's disease. Journal of Immunology (Baltimore, Md. : 1950). 194: 3422-31. PMID 25740948 DOI: 10.4049/Jimmunol.1401779  0.44
2015 Liu M, Shen S, Kendig DM, Mahavadi S, Murthy KS, Grider JR, Qiao LY. Inhibition of NMDAR reduces bladder hypertrophy and improves bladder function in cyclophosphamide induced cystitis. The Journal of Urology. 193: 1676-83. PMID 25572034 DOI: 10.1016/J.Juro.2014.12.092  0.315
2015 Nalli AD, Rajagopal S, Mahavadi S, Grider JR, Murthy KS. Inhibition of RhoA-dependent pathway and contraction by endogenous hydrogen sulfide in rabbit gastric smooth muscle cells. American Journal of Physiology. Cell Physiology. 308: C485-95. PMID 25567809 DOI: 10.1152/Ajpcell.00280.2014  0.606
2015 Rajagopal S, Nalli AD, Kumar DP, Bhattacharya S, Hu W, Mahavadi S, Grider JR, Murthy KS. Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation. The Journal of Pharmacology and Experimental Therapeutics. 352: 509-18. PMID 25550199 DOI: 10.1124/Jpet.114.221929  0.778
2015 Rico AL, Grants I, Needleman BJ, Williams KC, Soghomonyan S, Turco F, Cuomo R, Grider JR, Kendig DM, Murthy K, Harzman A, Ochoa-Cortes F, Christofi FL. 63 Gliomodulation of Neuronal and Motor Behavior in the Human GI Tract Gastroenterology. 148: S-18. DOI: 10.1016/S0016-5085(15)30063-9  0.303
2014 Anderson CD, Kendig DM, Al-Qudah M, Mahavadi S, Murthy KS, Grider JR. Role of various kinases in muscarinic M3 receptor-mediated contraction of longitudinal muscle of rat colon. Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi. 50: 103-19. PMID 25891767 DOI: 10.1540/Jsmr.50.103  0.587
2014 Bala V, Rajagopal S, Kumar DP, Nalli AD, Mahavadi S, Sanyal AJ, Grider JR, Murthy KS. Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-ε pathway and modulated by endogenous H2S. Frontiers in Physiology. 5: 420. PMID 25404917 DOI: 10.3389/Fphys.2014.00420  0.399
2014 Kendig DM, Hurst NR, Bradley ZL, Mahavadi S, Kuemmerle JF, Lyall V, DeSimone J, Murthy KS, Grider JR. Activation of the umami taste receptor (T1R1/T1R3) initiates the peristaltic reflex and pellet propulsion in the distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G1100-7. PMID 25324508 DOI: 10.1152/Ajpgi.00251.2014  0.392
2014 Rajagopal S, Nalli AD, Kumar DP, Bhattacharya S, Hu W, Mahavadi S, Grider JR, Murthy KS. Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation. The Journal of Pharmacology and Experimental Therapeutics. PMID 25204340 DOI: 10.1124/jpet.114.218156  0.7
2014 Mahavadi S, Nalli AD, Kumar DP, Hu W, Kuemmerle JF, Grider JR, Murthy KS. Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle. American Journal of Physiology. Cell Physiology. 307: C402-11. PMID 24944202 DOI: 10.1152/Ajpcell.00123.2014  0.563
2014 Nalli AD, Kumar DP, Al-Shboul O, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS. Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG. Cell Biochemistry and Biophysics. 70: 867-80. PMID 24777815 DOI: 10.1007/S12013-014-9992-6  0.545
2014 Nalli AD, Kumar DP, Mahavadi S, Al-Shboul O, Alkahtani R, Kuemmerle JF, Grider JR, Murthy KS. Hypercontractility of intestinal longitudinal smooth muscle induced by cytokines is mediated by the nuclear factor-κB/AMP-activated kinase/myosin light chain kinase pathway. The Journal of Pharmacology and Experimental Therapeutics. 350: 89-98. PMID 24769544 DOI: 10.1124/Jpet.113.212522  0.598
2014 Al-Shboul O, Nalli AD, Kumar DP, Zhou R, Mahavadi S, Kuemmerle JF, Grider JR, Murthy KS. Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation. American Journal of Physiology. Cell Physiology. 306: C1129-41. PMID 24740538 DOI: 10.1152/Ajpcell.00021.2014  0.602
2014 Li C, Micci MA, Murthy KS, Pasricha PJ. Substance P is essential for maintaining gut muscle contractility: a novel role for coneurotransmission revealed by botulinum toxin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G839-48. PMID 24699329 DOI: 10.1152/Ajpgi.00436.2012  0.525
2014 Huang J, Nalli AD, Mahavadi S, Kumar DP, Murthy KS. Inhibition of Gαi activity by Gβγ is mediated by PI 3-kinase-γ- and cSrc-dependent tyrosine phosphorylation of Gαi and recruitment of RGS12. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G802-10. PMID 24578342 DOI: 10.1152/Ajpgi.00440.2013  0.536
2014 Mahavadi S, Sriwai W, Huang J, Grider JR, Murthy KS. Inhibitory signaling by CB1 receptors in smooth muscle mediated by GRK5/β-arrestin activation of ERK1/2 and Src kinase. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G535-45. PMID 24407588 DOI: 10.1152/Ajpgi.00397.2013  0.559
2014 Al-Qudah M, Anderson CD, Mahavadi S, Bradley ZL, Akbarali HI, Murthy KS, Grider JR. Brain-derived neurotrophic factor enhances cholinergic contraction of longitudinal muscle of rabbit intestine via activation of phospholipase C. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G328-37. PMID 24356881 DOI: 10.1152/Ajpgi.00203.2013  0.548
2014 Mahavadi S, Nalli A, Al-Shboul O, Murthy KS. Inhibition of MLC20 phosphorylation downstream of Ca2+ and RhoA: A novel mechanism involving phosphorylation of myosin phosphatase interacting protein (M-RIP) by PKG and stimulation of MLC phosphatase activity. Cell Biochemistry and Biophysics. 68: 1-8. PMID 23723008 DOI: 10.1007/S12013-013-9677-6  0.518
2013 Mahavadi S, Bhattacharya S, Kumar DP, Clay C, Ross G, Akbarali HI, Grider JR, Murthy KS. Increased PDE5 activity and decreased Rho kinase and PKC activities in colonic muscle from caveolin-1-/- mice impair the peristaltic reflex and propulsion. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G964-74. PMID 24157969 DOI: 10.1152/Ajpgi.00165.2013  0.798
2013 Li C, Flynn RS, Grider JR, Murthy KS, Kellum JM, Akbari H, Kuemmerle JF. Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide. Inflammatory Bowel Diseases. 19: 2829-39. PMID 24051933 DOI: 10.1097/Mib.0B013E3182A8452E  0.373
2013 Sriwai W, Mahavadi S, Al-Shboul O, Grider JR, Murthy KS. Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA. Plos One. 8: e66743. PMID 23825105 DOI: 10.1371/Journal.Pone.0066743  0.527
2013 Alkahtani R, Mahavadi S, Al-Shboul O, Alsharari S, Grider JR, Murthy KS. Changes in the expression of smooth muscle contractile proteins in TNBS- and DSS-induced colitis in mice. Inflammation. 36: 1304-15. PMID 23794034 DOI: 10.1007/S10753-013-9669-0  0.518
2013 Bhattacharya S, Mahavadi S, Al-Shboul O, Rajagopal S, Grider JR, Murthy KS. Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1. American Journal of Physiology. Cell Physiology. 305: C334-47. PMID 23784544 DOI: 10.1152/Ajpcell.00334.2012  0.797
2013 Al-Shboul O, Mahavadi S, Sriwai W, Grider JR, Murthy KS. Differential expression of multidrug resistance protein 5 and phosphodiesterase 5 and regulation of cGMP levels in phasic and tonic smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G314-24. PMID 23764893 DOI: 10.1152/Ajpgi.00457.2012  0.574
2013 Ahmed R, Mahavadi S, Al-Shboul O, Bhattacharya S, Grider JR, Murthy KS. Characterization of signaling pathways coupled to melatonin receptors in gastrointestinal smooth muscle. Regulatory Peptides. 184: 96-103. PMID 23541890 DOI: 10.1016/J.Regpep.2013.03.028  0.791
2013 Mahavadi S, Bhattacharya S, Kim J, Fayed S, Al-Shboul O, Grider JR, Murthy KS. Caveolae-dependent internalization and homologous desensitization of VIP/PACAP receptor, VPAC₂, in gastrointestinal smooth muscle. Peptides. 43: 137-45. PMID 23499767 DOI: 10.1016/J.Peptides.2013.03.008  0.797
2013 Rajagopal S, Kumar DP, Mahavadi S, Bhattacharya S, Zhou R, Corvera CU, Bunnett NW, Grider JR, Murthy KS. Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G527-35. PMID 23275618 DOI: 10.1152/Ajpgi.00388.2012  0.8
2013 Sriwai W, Mahavadi S, Al-Shboul O, Grider JR, Murthy KS. Feedback inhibition of PAR2-AP-stimulated Rho kinase activity by PKA derived from NF-kB pathway. Plos One. DOI: 10.1371/Journal.Pone.0066743.G006  0.394
2012 Kumar DP, Rajagopal S, Mahavadi S, Mirshahi F, Grider JR, Murthy KS, Sanyal AJ. Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells. Biochemical and Biophysical Research Communications. 427: 600-5. PMID 23022524 DOI: 10.1016/J.Bbrc.2012.09.104  0.396
2012 Zhang Y, Li F, Liu S, Wang H, Mahavadi S, Murthy KS, Khalili K, Hu W. MEKK1-MKK4-JNK-AP1 pathway negatively regulates Rgs4 expression in colonic smooth muscle cells. Plos One. 7: e35646. PMID 22545125 DOI: 10.1371/Journal.Pone.0035646  0.544
2012 Kumar DP, Mahavadi S, Mirshahi F, Fuchs M, Murthy KS, Sanyal AJ. Mo2082 Expression and Function of the Transmembrane Bile Acid Receptor TGR5 in Human and Murine Pancreatic β Cells Gastroenterology. 143: e26. DOI: 10.1053/J.Gastro.2012.07.083  0.303
2012 Mahavadi S, Sriwai W, Kumar DP, Zhou R, Grider JR, Murthy KS. 491 Down-Regulation of MicroRNA-133a Due to Oxidative Stress Mediates Up-Regulation of RHOA Expression and Increase in Rho Kinase Activity and Gastric Muscle Contraction in Diabetes Gastroenterology. 142: S-105. DOI: 10.1016/S0016-5085(12)60396-5  0.46
2012 Bala V, Rajagopal S, Kumar DP, Mahavadi S, Zhou R, Bradley ZL, Bunnett NW, Corvera CU, Auwerx J, Grider JR, Sanyal AJ, Murthy KS. 202 Hydrogen Sulfide (H2S) Inhibits Bile Acid Receptor TGR5-Mediated GLP-1 Release From Enteroendrocrine Cells: Possible Involvement of H2S in Altered Glucose Metabolism in Diabetes Gastroenterology. 142: S-50. DOI: 10.1016/S0016-5085(12)60191-7  0.31
2011 Flynn RS, Mahavadi S, Murthy KS, Grider JR, Kellum JM, Akbari H, Kuemmerle JF. Endogenous IGFBP-3 regulates excess collagen expression in intestinal smooth muscle cells of Crohn's disease strictures. Inflammatory Bowel Diseases. 17: 193-201. PMID 20848532 DOI: 10.1002/Ibd.21351  0.466
2011 Mahavadi S, Flynn RS, Grider JR, Qiao LY, Murthy KS, Hazelgrove KB, Kuemmerle JF. Amelioration of excess collagen IαI, fibrosis, and smooth muscle growth in TNBS-induced colitis in IGF-I(+/-) mice. Inflammatory Bowel Diseases. 17: 711-9. PMID 20722057 DOI: 10.1002/Ibd.21437  0.445
2011 Sriwai W, Murthy KS, Srisawang P, Maladad K. Protease-Activated Receptor-2 Reduces Cyclohexamide-Induced Apoptosis in K562 Myeloid Leukemia Cells Gastroenterology. 140: S-477. DOI: 10.1016/S0016-5085(11)61964-1  0.319
2011 Mahavadi S, Grider JR, Murthy KS. O-Linked β-N-Acetylglucosamine Modification of Mypt1 Reciprocally Regulates Its Phosphorylation at Ser 695 and Thr 696 by PKG and Rho Kinase, Respectively: A Novel Mechanism That Contributes to Increased Smooth Muscle Tone in Diabetes Gastroenterology. 140: S-375. DOI: 10.1016/S0016-5085(11)61533-3  0.452
2011 Mahavadi S, Manion O, Ghosh S, Murthy KS. Activation of the Receptor for Advanced Glycation END Products (RAGE) and Oxidative Stress Mediate Up-Regulation of RHOA/Rho Kinase Pathway and Smooth Muscle Contraction in Diabetes Gastroenterology. 140: S-374. DOI: 10.1016/S0016-5085(11)61527-8  0.492
2011 Bala V, Mahavadi S, Lyall V, Murthy KS, Grider JR. Characterization of Receptors and Signaling Pathways Coupled to Umami Taste in Enteroendocrine Cells Gastroenterology. 140: S-324. DOI: 10.1016/S0016-5085(11)61313-9  0.317
2011 Bala V, Mahavadi S, Rajagopal S, Zhou R, Kuemmerle JF, Sanyal AJ, Murthy KS. Bile Acid-Induced Stimulation of ERK1/2 Activity, GLP-1 and PYY Release in Enteroendocrine Cells is Mediated by the Activation of Epac/PLC-ɛ Signaling Pathway via G S -Coupled TGR5 Gastroenterology. 140: S-147. DOI: 10.1016/S0016-5085(11)60598-2  0.377
2011 Flynn RS, Grider JR, Murthy KS, Bradley ZL, Kuemmerle JF. Cilengitide Blocks αVβ3 Integrin-Mediated, Rgd-Dependent Activation of Latent TGF-β1 and Attenuates Fibrosis in TNBS-Induced Colitis and Human Muscle of Stricturing Crohn's Disease Gastroenterology. 140: S-109. DOI: 10.1016/S0016-5085(11)60442-3  0.445
2011 Grider J, Bala V, Mahavadi S, Murthy K, Lyall V. The umami taste receptor ligand, monosodium glutamate, induces the peristaltic reflex in rat colon by activation of T1R1/T1R3 taste receptors Autonomic Neuroscience. 163: 62-63. DOI: 10.1016/J.Autneu.2011.05.073  0.323
2010 Li F, Hu DY, Liu S, Mahavadi S, Yen W, Murthy KS, Khalili K, Hu W. RNA-binding protein HuR regulates RGS4 mRNA stability in rabbit colonic smooth muscle cells. American Journal of Physiology. Cell Physiology. 299: C1418-29. PMID 20881234 DOI: 10.1152/Ajpcell.00093.2010  0.374
2010 Grider JR, Heuckeroth RO, Kuemmerle JF, Murthy KS. Augmentation of the ascending component of the peristaltic reflex and substance P release by glial cell line-derived neurotrophic factor Neurogastroenterology and Motility. 22: 779-786. PMID 20331804 DOI: 10.1111/J.1365-2982.2010.01489.X  0.315
2010 Li F, Murthy KS, Khalili K, Hu W. Cloning and characterization of rabbit Rgs4 promoter in gut smooth muscle. Gene. 451: 45-53. PMID 19945517 DOI: 10.1016/J.Gene.2009.11.010  0.401
2010 Flynn RS, Murthy KS, Grider JR, Kellum JM, Kuemmerle JF. Endogenous IGF-I and alphaVbeta3 integrin ligands regulate increased smooth muscle hyperplasia in stricturing Crohn's disease. Gastroenterology. 138: 285-93. PMID 19751734 DOI: 10.1053/J.Gastro.2009.09.003  0.452
2010 Mahavadi S, Grider JR, Murthy KS. W1772 Regulation of Receptor-Mediated RHOA/Rho Kinase Pathway and Muscle Contraction by Caveolin-1 in Colonic Smooth Muscle Gastroenterology. 138: S-736-S-737. DOI: 10.1016/S0016-5085(10)63392-6  0.586
2010 Mahavadi S, Grider JR, Murthy KS, Pintar JE, Kuemmerle JF. M1814 Endogenous IGFBP-5 Regulates IGF-I Expression and Intestinal Smooth Muscle Cell Hyperplasia Gastroenterology. 138: S-424. DOI: 10.1016/S0016-5085(10)61957-9  0.482
2010 Alkahtani RM, Mahavadi S, Manion O, Sriwai W, Murthy KS. S2075 Changes in the Expression of Thin Filament-Associated Proteins in Colonic Smooth Muscle From Mice During TNBS-Induced Colitis Gastroenterology. 138: S-314. DOI: 10.1016/S0016-5085(10)61447-3  0.468
2010 Mahavadi S, Gangula PR, Ghosh S, Kuemmerle JF, Grider JR, Murthy KS. S2057 Diabetes-Induced Changes in the Expression of Proteins Involved in the Regulation of Sustained Mlc20 Phosphorylation and cGMP Levels in Gastrointestinal Smooth Muscle Gastroenterology. 138: S-311. DOI: 10.1016/S0016-5085(10)61429-1  0.522
2009 Flynn RS, Mahavadi S, Murthy KS, Kellum JM, Kuemmerle JF. Insulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of G{alpha}i3. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G1232-8. PMID 19808657 DOI: 10.1152/Ajpgi.00323.2009  0.498
2009 Grider JR, Mahavadi S, Li Y, Qiao LY, Kuemmerle JF, Murthy KS, Martin BR. Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G539-49. PMID 19589944 DOI: 10.1152/Ajpgi.00064.2009  0.334
2009 Lyall V, Phan TH, Mummalaneni S, Melone P, Mahavadi S, Murthy KS, DeSimone JA. Regulation of the benzamil-insensitive salt taste receptor by intracellular Ca2+, protein kinase C, and calcineurin. Journal of Neurophysiology. 102: 1591-605. PMID 19553475 DOI: 10.1152/Jn.91301.2008  0.375
2009 Hu W, Li F, Mahavadi S, Murthy KS. Upregulation of RGS4 expression by IL-1beta in colonic smooth muscle is enhanced by ERK1/2 and p38 MAPK and inhibited by the PI3K/Akt/GSK3beta pathway. American Journal of Physiology. Cell Physiology. 296: C1310-20. PMID 19369446 DOI: 10.1152/Ajpcell.00573.2008  0.409
2009 Li F, Deng W, Yen W, Murthy KS, Hu W. W1596 GATA-6 Mediates IL-1β-Induced Up-Regulation of RGS4 in Rabbit Colonic Smooth Muscle Cells Gastroenterology. 136: A-699. DOI: 10.1016/S0016-5085(09)63221-2  0.459
2009 Grider JR, Mahavadi S, Ross GR, Akbarali HI, Murthy KS. M1738 Caveolin-1 Regulates Colonic Propulsion By Inhibiting cGMP-Specific PDE5 Activity and Enhancing cGMP/PKG-Mediated Muscle Relaxation Gastroenterology. 136: A-421. DOI: 10.1016/S0016-5085(09)61938-7  0.535
2009 Sriwai W, Mahavadi S, Murthy KS. S1624 Inhibition of Sustained Smooth Muscle Contraction By PKA and PKG Is Mediated By Phosphorylation of Gα13 and Inhibition of Gα13-Dependent Activation of RHOA Gastroenterology. 136: A-237. DOI: 10.1016/S0016-5085(09)61070-2  0.417
2009 Fayed S, Mahavadi S, Kim J, Khaleduzzaman M, Ahmed SR, Murthy KS. S1622 Characterization of Ghrelin Receptors and Signaling Pathways in Gastric Smooth Muscle Gastroenterology. 136: A-236. DOI: 10.1016/S0016-5085(09)61068-4  0.364
2009 Mahavadi S, Khaleduzzaman M, Grider JR, Murthy KS. S1619 Inhibition of GβγI-Dependent PLC-β3 Activity By PKA and PKG Is Mediated By Phosphorylation of PLC-β3 and GαI-GTPase-Activating Protein RGS2 Gastroenterology. 136: A-236. DOI: 10.1016/S0016-5085(09)61065-9  0.338
2009 Kim J, Fayed S, Mahavadi S, Ross GR, Ahmed SR, Khaleduzzaman M, Murthy KS. 607 Caveolae-Dependent Internalization and Homologous Desensitization of VIP/PACAP Receptor, VPAC2 in Gastrointestinal Smooth Muscle Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60442-X  0.532
2009 Al-Shboul O, Mahavadi S, Strane C, Murthy KS. 269 Expression of AMP-Activated Kinase (AMP Kinase) and Inactivation of Myosin Light Chain (MLC) Kinase By AMP Kinase Determines the Magnitude of Smooth Muscle Contraction in Different Regions of the Stomach Gastroenterology. 136: A-52. DOI: 10.1016/S0016-5085(09)60234-1  0.481
2008 Grider JR, Murthy KS. Autoinhibition of endothelial nitric oxide synthase (eNOS) in gut smooth muscle by nitric oxide. Regulatory Peptides. 151: 75-9. PMID 18926858 DOI: 10.1016/J.Regpep.2008.09.005  0.529
2008 Hu W, Li F, Mahavadi S, Murthy KS. Interleukin-1beta up-regulates RGS4 through the canonical IKK2/IkappaBalpha/NF-kappaB pathway in rabbit colonic smooth muscle. The Biochemical Journal. 412: 35-43. PMID 18260825 DOI: 10.1042/Bj20080042  0.43
2008 Sriwai W, Zhou H, Murthy KS. G(q)-dependent signalling by the lysophosphatidic acid receptor LPA(3) in gastric smooth muscle: reciprocal regulation of MYPT1 phosphorylation by Rho kinase and cAMP-independent PKA. The Biochemical Journal. 411: 543-51. PMID 18237278 DOI: 10.1042/Bj20071299  0.491
2008 Murthy KS. Contractile agonists attenuate cGMP levels by stimulating phosphorylation of cGMP-specific PDE5; an effect mediated by RhoA/PKC-dependent inhibition of protein phosphatase 1. British Journal of Pharmacology. 153: 1214-24. PMID 18204475 DOI: 10.1038/sj.bjp.0707686  0.445
2008 Murthy KS. Inhibitory phosphorylation of soluble guanylyl cyclase by muscarinic m2 receptors via Gbetagamma-dependent activation of c-Src kinase. The Journal of Pharmacology and Experimental Therapeutics. 325: 183-9. PMID 18180373 DOI: 10.1124/Jpet.107.132928  0.564
2008 Murthy KS, Mahavadi S, Huang J, Zhou H, Sriwai W. Phosphorylation of GRK2 by PKA augments GRK2-mediated phosphorylation, internalization, and desensitization of VPAC2 receptors in smooth muscle. American Journal of Physiology. Cell Physiology. 294: C477-87. PMID 18077607 DOI: 10.1152/Ajpcell.00229.2007  0.516
2008 Murthy KS, Sriwai W. Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G327-35. PMID 18006600 DOI: 10.1152/Ajpgi.00430.2007  0.558
2008 Murthy KS, Mahavadi S. W1756 Association of Soluble Guanylyl Cyclase with 90-Kda Heat Shock Protein (Hsp90) Regulates sGC Expression and Activity and Nitric Oxide-Mediated Smooth Muscle Relaxation Gastroenterology. 134: A-709. DOI: 10.1016/S0016-5085(08)63311-9  0.441
2008 Hu W, Li F, Mahavadi S, Murthy KS. W1750 Binding of HuR to Au-Rich Elements Within Rgs4 3'-Untranslated Region Is a Critical Determinant of Rgs4 mRNA Stability in Smooth Muscle Cells Gastroenterology. 134: A-708. DOI: 10.1016/S0016-5085(08)63305-3  0.402
2008 Mahavadi S, Hu W, Li F, Zhou H, Akbarali HI, Murthy KS. T1371 Down-Regulation of Caveolin-1 in Smooth Muscle from TNBS-Induced Colitis Mediates the Increase in Phosphodiesterase-5 Activity and Decrease in cGMP-Induced Muscle Relaxation Gastroenterology. 134: A-541. DOI: 10.1016/S0016-5085(08)62526-3  0.54
2008 Sriwai W, Murthy KS. T1370 Expression of Multi-Drug Resistance Protein 5 (MRP5), a cGMP Export Pump in Gastrointestinal Smooth Muscle Gastroenterology. 134: A-541. DOI: 10.1016/S0016-5085(08)62525-1  0.396
2008 Mahavadi S, Murthy KS. S1695 Inhibitory Phosphorylation of Soluble Guanylyl Cyclase Induced By Cannabinoid CB1 Agonist Is Mediated By C-SRC Kinase and Dependent On Internalization of CB1 Receptors Via GRK5: A Mechanism for Inhibition of Smooth Muscle Relaxation By Cannabinoids Gastroenterology. 134: A-251-A-252. DOI: 10.1016/S0016-5085(08)61166-X  0.557
2008 Sriwai W, Mahavadi S, Li F, Hu W, Murthy KS. S1686 Sustained Contraction of Smooth Muscle By PAR1 Receptors Is Selectively Mediated By RhoA/PKC/Cpi-17 Pathway: Evidence That Co-Activation of the RhoA/Rho Kinase/Mypt1 Pathway Is Suppressed By PKA Released from IκBα Gastroenterology. 134: A-250. DOI: 10.1016/S0016-5085(08)61157-9  0.558
2008 Hu W, Li F, Deng W, Murthy KS. S1683 Regulation of Constitutive and IL-1β-Induced RGS4 Expression in Smooth Muscle Cells Is Mediated Via MEKK1-JNK-Ap1 Pathway Gastroenterology. 134: A-249. DOI: 10.1016/S0016-5085(08)61154-3  0.465
2008 Mahavadi S, Sriwai W, Murthy KS. S1675 Expression of Myosin Light Chain (MLC) Phosphatase Activator (Telokin) and Inhibitor (CPI-17) Determines the Magnitude of Smooth Muscle Relaxation and Contraction, Respectively, in Different Regions of the Stomach Gastroenterology. 134: A-247. DOI: 10.1016/S0016-5085(08)61146-4  0.505
2007 Hu W, Mahavadi S, Li F, Murthy KS. Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1beta. American Journal of Physiology. Cell Physiology. 293: C1991-2000. PMID 17959727 DOI: 10.1152/Ajpcell.00300.2007  0.508
2007 Song Y, Wilkins P, Hu W, Murthy KS, Chen J, Lee Z, Oyesanya R, Wu J, Barbour SE, Fang X. Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells. The Biochemical Journal. 406: 427-36. PMID 17555408 DOI: 10.1042/Bj20070631  0.332
2007 Huang J, Mahavadi S, Sriwai W, Grider JR, Murthy KS. Cross-regulation of VPAC(2) receptor desensitization by M(3) receptors via PKC-mediated phosphorylation of RKIP and inhibition of GRK2. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G867-74. PMID 17170028 DOI: 10.1152/Ajpgi.00326.2006  0.532
2007 Mahavadi S, Huang J, Sriwai W, Rao KR, Murthy KS. Cross-regulation of VPAC2 receptor internalization by m2 receptors via c-Src-mediated phosphorylation of GRK2. Regulatory Peptides. 139: 109-14. PMID 17169446 DOI: 10.1016/J.Regpep.2006.10.013  0.462
2007 Huang J, Zhou H, Mahavadi S, Sriwai W, Murthy KS. Inhibition of Galphaq-dependent PLC-beta1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2. American Journal of Physiology. Cell Physiology. 292: C200-8. PMID 16885398 DOI: 10.1152/Ajpcell.00103.2006  0.493
2006 Choudhury J, Mirshahi F, Murthy KS, Yager DR, Sanyal AJ. Physiologic concentrations of leptin increase collagen production by non-immortalized human hepatic stellate cells. Metabolism: Clinical and Experimental. 55: 1317-22. PMID 16979401 DOI: 10.1016/J.Metabol.2006.05.016  0.327
2006 Zhou H, Huang J, Murthy KS. Molecular cloning and functional expression of a VIP-specific receptor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G728-34. PMID 16959956 DOI: 10.1152/Ajpgi.00138.2006  0.488
2006 Hu W, Mahavadi S, Huang J, Li F, Murthy KS. Characterization of S1P1 and S1P2 receptor function in smooth muscle by receptor silencing and receptor protection. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G605-10. PMID 16675745 DOI: 10.1152/Ajpgi.00147.2006  0.45
2006 Hu W, Huang J, Mahavadi S, Li F, Murthy KS. Lentiviral siRNA silencing of sphingosine-1-phosphate receptors S1P1 and S1P2 in smooth muscle. Biochemical and Biophysical Research Communications. 343: 1038-44. PMID 16574065 DOI: 10.1016/J.Bbrc.2006.03.079  0.476
2006 Huang J, Mahavadi S, Sriwai W, Hu W, Murthy KS. Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway. The Biochemical Journal. 396: 193-200. PMID 16472257 DOI: 10.1042/Bj20051772  0.528
2006 Murthy KS. Signaling for contraction and relaxation in smooth muscle of the gut. Annual Review of Physiology. 68: 345-74. PMID 16460276 DOI: 10.1146/Annurev.Physiol.68.040504.094707  0.543
2005 Huang J, Zhou H, Mahavadi S, Sriwai W, Lyall V, Murthy KS. Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G23-31. PMID 15591586 DOI: 10.1152/Ajpgi.00305.2004  0.502
2005 Misra S, Mahavadi S, Grider JR, Murthy KS. Differential expression of Y receptors and signaling pathways in intestinal circular and longitudinal smooth muscle. Regulatory Peptides. 125: 163-72. PMID 15582728 DOI: 10.1016/J.Regpep.2004.08.020  0.55
2004 Murthy KS, Zhou H, Huang J, Pentyala SN. Activation of PLC-delta1 by Gi/o-coupled receptor agonists. American Journal of Physiology. Cell Physiology. 287: C1679-87. PMID 15525688 DOI: 10.1152/Ajpcell.00257.2004  0.449
2004 Hersch E, Huang J, Grider JR, Murthy KS. Gq/G13 signaling by ET-1 in smooth muscle: MYPT1 phosphorylation via ETA and CPI-17 dephosphorylation via ETB. American Journal of Physiology. Cell Physiology. 287: C1209-18. PMID 15475516 DOI: 10.1152/Ajpcell.00198.2004  0.539
2004 Murthy KS. Modulation of soluble guanylate cyclase activity by phosphorylation. Neurochemistry International. 45: 845-51. PMID 15312978 DOI: 10.1016/J.Neuint.2004.03.014  0.505
2004 Misra S, Murthy KS, Zhou H, Grider JR. Coexpression of Y1, Y2, and Y4 receptors in smooth muscle coupled to distinct signaling pathways. The Journal of Pharmacology and Experimental Therapeutics. 311: 1154-62. PMID 15308651 DOI: 10.1124/Jpet.104.071415  0.452
2004 Kuemmerle JF, Murthy KS, Bowers JG. IGFBP-3 activates TGF-beta receptors and directly inhibits growth in human intestinal smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 287: G795-802. PMID 15178549 DOI: 10.1152/Ajpgi.00009.2004  0.441
2004 Zhou H, Murthy KS. Distinctive G protein-dependent signaling in smooth muscle by sphingosine 1-phosphate receptors S1P1 and S1P2. American Journal of Physiology. Cell Physiology. 286: C1130-8. PMID 15075212 DOI: 10.1152/Ajpcell.00429.2003  0.501
2003 Rosenfeldt HM, Amrani Y, Watterson KR, Murthy KS, Panettieri RA, Spiegel S. Sphingosine-1-phosphate stimulates contraction of human airway smooth muscle cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1789-99. PMID 14519658 DOI: 10.1096/Fj.02-0836Com  0.495
2003 Murthy KS, Zhou H, Grider JR, Makhlouf GM. Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G1006-16. PMID 12736149 DOI: 10.1152/Ajpgi.00465.2002  0.564
2003 Murthy KS, Zhou H, Grider JR, Brautigan DL, Eto M, Makhlouf GM. Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. The Biochemical Journal. 374: 145-55. PMID 12733988 DOI: 10.1042/Bj20021274  0.493
2003 Zhou H, Murthy KS. Identification of the G protein-activating sequence of the single-transmembrane natriuretic peptide receptor C (NPR-C). American Journal of Physiology. Cell Physiology. 284: C1255-61. PMID 12676657 DOI: 10.1152/Ajpcell.00520.2002  0.302
2003 Zhou H, Das S, Murthy KS. Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA2 by m3 and m2 receptors. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G472-80. PMID 12576304 DOI: 10.1152/Ajpgi.00345.2002  0.441
2003 Murthy KS, Zhou H. Selective phosphorylation of the IP3R-I in vivo by cGMP-dependent protein kinase in smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G221-30. PMID 12529267 DOI: 10.1152/Ajpgi.00401.2002  0.497
2003 Rao JN, Guo X, Liu L, Zou T, Murthy KS, Yuan JX, Wang JY. Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. American Journal of Physiology. Cell Physiology. 284: C848-59. PMID 12466151 DOI: 10.1152/Ajpcell.00371.2002  0.43
2003 Murthy KS, Zhou H, Grider JR, Makhlouf GM. Stimulatory phosphorylation of cyclic GMP-specific phosphodiesterase 5 (PDE5) by contractile agonists is mediated by RhoA/PKC-dependent inactivation of protein phosphatase type 1 (PP1) Gastroenterology. 124: A465. DOI: 10.1016/S0016-5085(03)82350-8  0.417
2003 Zhou H, Murthy KS. Inhibitory phosphorylation of IP3 receptor type I (IP3R-I) In vivo is selectively mediated by cyclic GMP-dependent protein kinase-1α (PKG-1α) in gastric smooth muscle Gastroenterology. 124: A137. DOI: 10.1016/S0016-5085(03)80676-5  0.52
2003 Zhou H, Mahavadi S, Murthy KS. Transfection of NOS-III into NOS-III deficient tenia coli smooth muscle cells unmasks a novel mechanism of activation of NOS-III via PI 3-Kinase/Akt-dependent phosphorylation Gastroenterology. 124: A136. DOI: 10.1016/S0016-5085(03)80675-3  0.503
2003 Zhou H, Murthy KS, Das S, Grider JR, Makhlouf GM. Multiple signaling pathways for EDG (endothelial differentiation gene) receptors in gastric smooth muscle Gastroenterology. 124: A77-A78. DOI: 10.1016/S0016-5085(03)80383-9  0.453
2002 Murthy KS, Zhou H, Makhlouf GM. PKA-dependent activation of PDE3A and PDE4 and inhibition of adenylyl cyclase V/VI in smooth muscle. American Journal of Physiology. Cell Physiology. 282: C508-17. PMID 11832336 DOI: 10.1152/Ajpcell.00373.2001  0.555
2001 Murthy KS. Activation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth muscle. The Biochemical Journal. 360: 199-208. PMID 11696008 DOI: 10.1042/0264-6021:3600199  0.499
2001 Murthy KS. cAMP inhibits IP(3)-dependent Ca(2+) release by preferential activation of cGMP-primed PKG. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1238-45. PMID 11668033 DOI: 10.1152/Ajpgi.2001.281.5.G1238  0.553
2001 Teng BQ, Grider JR, Murthy KS. Identification of a VIP-specific receptor in guinea pig tenia coli. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G718-25. PMID 11518684 DOI: 10.1152/Ajpgi.2001.281.3.G718  0.398
2001 Murthy KS, Zhou H, Grider JR, Makhlouf GM. Sequential activation of heterotrimeric and monomeric G proteins mediates PLD activity in smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G381-8. PMID 11171620 DOI: 10.1152/Ajpgi.2001.280.3.G381  0.411
2001 Kuemmerle JF, Murthy KS. Coupling of the insulin-like growth factor-I receptor tyrosine kinase to Gi2 in human intestinal smooth muscle: Gbetagamma -dependent mitogen-activated protein kinase activation and growth. Journal of Biological Chemistry. 276: 7187-7194. PMID 11120746 DOI: 10.1074/Jbc.M011145200  0.496
2001 MURTHY KS. Activation of phosphodiesterase 5 and inhibition of guanylate cyclase by cGMP-dependent protein kinase in smooth muscle Biochemical Journal. 360: 199-208. DOI: 10.1042/bj3600199  0.405
2001 Grider JR, Murthy KS, Kuemmerle JF. Stimulation of substance P (SP) release from myenteric synaptosomes by BDNF is mediated by p42/44 MAP kinase Gastroenterology. 120: A308. DOI: 10.1016/S0016-5085(08)81530-2  0.305
2001 Murthy KS, Zhou H, Grider JR, Makhiouf GM. Inhibition of RhoA-dependent sustained smooth muscie contraction by cAMP-and cGMP-dependent protein kinase (PKA and PKG) Gastroenterology. 120: A201. DOI: 10.1016/S0016-5085(08)80997-3  0.463
2001 Murthy KS, Zhou H, Makhlouf GM. Differential signaling by muscarinic m3 and m2 receptors determines sustained myosin light chain (MLC) phosphorylation and smooth muscle contraction Gastroenterology. 120: A20. DOI: 10.1016/S0016-5085(08)80097-2  0.462
2000 Murthy KS, Grider JR, Makhlouf GM. Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G(i-1) and G(i-2). American Journal of Physiology. Cell Physiology. 279: C925-34. PMID 11003572 DOI: 10.1152/Ajpcell.2000.279.4.C925  0.492
2000 Murthy KS, Grider JR, Kuemmerle JF, Makhlouf GM. Sustained muscle contraction induced by agonists, growth factors, and Ca(2+) mediated by distinct PKC isozymes. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G201-10. PMID 10898764 DOI: 10.1152/Ajpgi.2000.279.1.G201  0.51
2000 Murthy KS, Makhlouf GM. Heterologous desensitization mediated by G protein-specific binding to caveolin. The Journal of Biological Chemistry. 275: 30211-9. PMID 10862762 DOI: 10.1074/Jbc.M002194200  0.351
2000 Murthy KS, Teng BQ, Zhou H, Jin JG, Grider JR, Makhlouf GM. G(i-1)/G(i-2)-dependent signaling by single-transmembrane natriuretic peptide clearance receptor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 278: G974-80. PMID 10859228 DOI: 10.1152/Ajpgi.2000.278.6.G974  0.513
2000 Murthy KS, Makhlouf GM. Sustained activation of phospholipase A2 (PLA2) in smooth muscle cells by acetylcholine is mediated by concurrent M3-dependent activation of P42/P44 MAP kinase and M2-dependent activation of P38 MAP kinase Gastroenterology. 118: A713. DOI: 10.1016/S0016-5085(00)84983-5  0.427
2000 Murthy KS, Makhlouf GM. Capacitative Ca2+ influx in smooth muscle is mediated by the cytochrome P450 monoxygenase product, 5,6-epoxyeicosatrienoic acid (5,6-EET) Gastroenterology. 118: A90. DOI: 10.1016/S0016-5085(00)82436-1  0.427
2000 Murthy KS, Makhlouf GM. G protein-independent activation of phospholipase C-Δ1 (PLC-Δ1) in intestinal smooth muscle is mediated by capacitative Ca2+ influx Gastroenterology. 118: A89. DOI: 10.1016/S0016-5085(00)82435-X  0.475
1999 Murthy KS, Makhlouf GM. Identification of the G protein-activating domain of the natriuretic peptide clearance receptor (NPR-C). The Journal of Biological Chemistry. 274: 17587-92. PMID 10364194 DOI: 10.1074/Jbc.274.25.17587  0.335
1999 Murthy KS, Makhlouf GM. Differential regulation of phospholipase A2 (PLA2)-dependent Ca2+ signaling in smooth muscle by cAMP- and cGMP-dependent protein kinases. Inhibitory phosphorylation of PLA2 by cyclic nucleotide-dependent protein kinases. The Journal of Biological Chemistry. 273: 34519-26. PMID 9852121 DOI: 10.1074/Jbc.273.51.34519  0.488
1999 Teng B, Murthy KS, Kuemmerle JF, Grider JR, Makhlouf GM. Selective expression of vasoactive intestinal peptide (VIP)2/pituitary adenylate cyclase-activating polypeptide (PACAP)3 receptors in rabbit and guinea pig gastric and tenia coli smooth muscle cells. Regulatory Peptides. 77: 127-34. PMID 9809806 DOI: 10.1016/S0167-0115(98)00112-8  0.478
1998 Murthy KS, Makhlouf GM. cGMP-mediated Carelease from IP-insensitive Castores in smooth muscle. American Journal of Physiology. Cell Physiology. 274: C1199-C1205. PMID 29591072 DOI: 10.1152/Ajpcell.1998.274.5.C1199  0.544
1998 Murthy KS, Teng BQ, Jin JG, Makhlouf GM. G protein-dependent activation of smooth muscle eNOS via natriuretic peptide clearance receptor. American Journal of Physiology. Cell Physiology. 275: C1409-C1416. PMID 29585753 DOI: 10.1152/Ajpcell.1998.275.6.C1409  0.517
1998 Teng BQ, Murthy KS, Kuemmerle JF, Grider JR, Sase K, Michel T, Makhlouf GM. Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G342-G351. PMID 29585533 DOI: 10.1152/Ajpgi.1998.275.2.G342  0.493
1998 Murthy KS, Makhlouf GM. Regulation of adenylyl cyclase type V/VI in smooth muscle: interplay of inhibitory G protein and Ca2+ influx. Molecular Pharmacology. 54: 122-8. PMID 9658197 DOI: 10.1124/Mol.54.1.122  0.428
1998 Murthy KS, Makhlouf GM. Coexpression of ligand-gated P2X and G protein-coupled P2Y receptors in smooth muscle. Preferential activation of P2Y receptors coupled to phospholipase C (PLC)-beta1 via Galphaq/11 and to PLC-beta3 via Gbetagammai3. The Journal of Biological Chemistry. 273: 4695-704. PMID 9468531 DOI: 10.1074/Jbc.273.8.4695  0.41
1998 Murthy K, Makhlouf G. Inhibitory regulation of adenylyl cyclase types V/VI in smooth muscle is mediated by interplay of G13 and Ca2+ influx Gastroenterology. 114: A1167. DOI: 10.1016/S0016-5085(98)84745-8  0.357
1998 Murthy K, Makhlouf G. G13-mediated activation of PLD induces translocation of PKC-ε and sustained muscle contraction Gastroenterology. 114: A1167. DOI: 10.1016/S0016-5085(98)84744-6  0.447
1998 Teng B, Murthy K, Jin J, Makhlouf G. Functional expression of natriuretic peptide clearance receptor (NPR-C) in rabbit gastric muscle cells Gastroenterology. 114: A846. DOI: 10.1016/S0016-5085(98)83447-1  0.336
1998 Murthy K, Jin J, Teng B, Grider J, Makhlouf G. The natriuretic peptide clearance receptor (NPR-C) is coupled via inhibitory G proteins to activation of PLC-β and inhibition of adenylyl cyclase in tenia coli Gastroenterology. 114: A808. DOI: 10.1016/S0016-5085(98)83298-8  0.346
1997 Kuemmerle JF, Murthy KS, Makhlouf GM. Longitudinal smooth muscle of the mammalian intestine. A model for Ca2+ signaling by cADPR. Cell Biochemistry and Biophysics. 28: 31-44. PMID 9386891 DOI: 10.1007/Bf02738308  0.43
1997 Murthy KS, Makhlouf GM. Differential coupling of muscarinic m2 and m3 receptors to adenylyl cyclases V/VI in smooth muscle. Concurrent M2-mediated inhibition via Galphai3 and m3-mediated stimulation via Gbetagammaq. The Journal of Biological Chemistry. 272: 21317-24. PMID 9261144 DOI: 10.1074/Jbc.272.34.21317  0.468
1997 Murthy KS, Jin JG, Grider JR, Makhlouf GM. Characterization of PACAP receptors and signaling pathways in rabbit gastric muscle cells. The American Journal of Physiology. 272: G1391-9. PMID 9227474 DOI: 10.1152/Ajpgi.1997.272.6.G1391  0.483
1997 Makhlouf GM, Murthy KS. Signal transduction in gastrointestinal smooth muscle. Cellular Signalling. 9: 269-76. PMID 9218127 DOI: 10.1016/S0898-6568(96)00180-5  0.481
1996 Murthy KS, Coy DH, Makhlouf GM. Somatostatin receptor-mediated signaling in smooth muscle. Activation of phospholipase C-beta3 by Gbetagamma and inhibition of adenylyl cyclase by Galphai1 and Galphao. The Journal of Biological Chemistry. 271: 23458-63. PMID 8798553 DOI: 10.1074/Jbc.271.38.23458  0.466
1996 Jin JG, Murthy KS, Grider JR, Makhlouf GM. Stoichiometry of neurally induced VIP release, NO formation, and relaxation in rabbit and rat gastric muscle. The American Journal of Physiology. 271: G357-69. PMID 8770052 DOI: 10.1152/Ajpgi.1996.271.2.G357  0.454
1995 Murthy KS, Makhlouf GM. Interaction of cA-kinase and cG-kinase in mediating relaxation of dispersed smooth muscle cells. The American Journal of Physiology. 268: C171-80. PMID 7840145 DOI: 10.1152/Ajpcell.1995.268.1.C171  0.512
1995 Murthy KS, Kuemmerle JF, Makhlouf GM. Agonist-mediated activation of PLA2 initiates Ca2+ mobilization in intestinal longitudinal smooth muscle. The American Journal of Physiology. 269: G93-102. PMID 7631804 DOI: 10.1152/Ajpgi.1995.269.1.G93  0.412
1995 Kuemmerle JF, Murthy KS, Grider JR, Martin DC, Makhlouf GM. Coexpression of 5-HT2A and 5-HT4 receptors coupled to distinct signaling pathways in human intestinal muscle cells. Gastroenterology. 109: 1791-800. PMID 7498643 DOI: 10.1016/0016-5085(95)90745-9  0.392
1995 Murthy KS, Makhlouf GM. Functional characterization of phosphoinositide-specific phospholipase C-beta 1 and -beta 3 in intestinal smooth muscle. The American Journal of Physiology. 269: C969-78. PMID 7485467 DOI: 10.1152/Ajpcell.1995.269.4.C969  0.426
1994 Murthy KS, Makhlouf GM. Fluoride activates G protein-dependent and -independent pathways in dispersed intestinal smooth muscle cells. Biochemical and Biophysical Research Communications. 202: 1681-7. PMID 8060357 DOI: 10.1006/Bbrc.1994.2128  0.458
1994 Kuemmerle JF, Murthy KS, Makhlouf GM. Agonist-activated, ryanodine-sensitive, IP3-insensitive Ca2+ release channels in longitudinal muscle of intestine. The American Journal of Physiology. 266: C1421-31. PMID 7515567 DOI: 10.1152/Ajpcell.1994.266.5.C1421  0.397
1994 Murthy KS, Jin JG, Makhlouf GM. Inhibition of nitric oxide synthase activity in dispersed gastric muscle cells by protein kinase C. The American Journal of Physiology. 266: G161-5. PMID 7508198 DOI: 10.1152/Ajpgi.1994.266.1.G161  0.54
1993 Murthy KS, Severi C, Grider JR, Makhlouf GM. Inhibition of IP3 and IP3-dependent Ca2+ mobilization by cyclic nucleotides in isolated gastric muscle cells. The American Journal of Physiology. 264: G967-74. PMID 8388644 DOI: 10.1152/Ajpgi.1993.264.5.G967  0.4
1993 Jin JG, Murthy KS, Grider JR, Makhlouf GM. Activation of distinct cAMP- and cGMP-dependent pathways by relaxant agents in isolated gastric muscle cells. The American Journal of Physiology. 264: G470-7. PMID 8384796 DOI: 10.1152/Ajpgi.1993.264.3.G470  0.552
1993 Chijiiwa Y, Murthy KS, Grider JR, Makhlouf GM. Expression of functional receptors for vasoactive intestinal peptide in freshly isolated and cultured gastric muscle cells. Regulatory Peptides. 47: 223-32. PMID 8234906 DOI: 10.1016/0167-0115(93)90389-P  0.425
1993 Murthy KS, Zhang KM, Jin JG, Grider JR, Makhlouf GM. VIP-mediated G protein-coupled Ca2+ influx activates a constitutive NOS in dispersed gastric muscle cells. The American Journal of Physiology. 265: G660-71. PMID 7694477 DOI: 10.1152/Ajpgi.1993.265.4.G660  0.56
1992 Murthy KS, Makhlouf GM. Phosphoinositide metabolism in intestinal smooth muscle: preferential production of Ins(1,4,5)P3 in circular muscle cells. The American Journal of Physiology. 261: G945-51. PMID 1662916 DOI: 10.1152/Ajpgi.1991.261.6.G945  0.523
1992 Murthy KS, Grider JR, Makhlouf GM. InsP3-dependent Ca2+ mobilization in circular but not longitudinal muscle cells of intestine. The American Journal of Physiology. 261: G937-44. PMID 1662915 DOI: 10.1152/Ajpgi.1991.261.6.G937  0.524
1992 Grider JR, Murthy KS, Jin JG, Makhlouf GM. Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release. The American Journal of Physiology. 262: G774-8. PMID 1566853 DOI: 10.1152/Ajpgi.1992.262.4.G774  0.499
1991 McHenry L, Murthy KS, Grider JR, Makhlouf GM. Inhibition of muscle cell relaxation by somatostatin: tissue-specific, cAMP-dependent, pertussis toxin-sensitive. The American Journal of Physiology. 261: G45-9. PMID 1677535 DOI: 10.1152/Ajpgi.1991.261.1.G45  0.554
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