| Year |
Citation |
Score |
| 2023 |
Jin Z, Zhao L, Chang Y, Jin R, Hu F, Wu S, Xue Z, Ma Y, Chen C, Zheng M, Chang Y, Jin H, Xie Q, Huang C, Huang H. CRTAC1 enhances the chemosensitivity of non-small cell lung cancer to cisplatin by eliciting RyR-mediated calcium release and inhibiting Akt1 expression. Cell Death & Disease. 14: 563. PMID 37633993 DOI: 10.1038/s41419-023-06088-1 |
0.322 |
|
| 2023 |
Tian Z, Hua X, Zhu J, Li P, Chen R, Li X, Li T, Zhou C, Huang C. ATG7 upregulation contributes to malignant transformation of human bronchial epithelial cells by B[a]PDE via DNMT3B protein degradation and miR-494 promoter methylation. Ecotoxicology and Environmental Safety. 263: 115273. PMID 37480691 DOI: 10.1016/j.ecoenv.2023.115273 |
0.326 |
|
| 2023 |
Huang S, Li J, Wu S, Zheng Z, Wang C, Li H, Zhao L, Zhang X, Huang H, Huang C, Xie Q. C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis. Oncogene. PMID 36882524 DOI: 10.1038/s41388-023-02656-z |
0.328 |
|
| 2022 |
Zhu J, Huang S, Li Y, Xu J, Chen R, Guo M, Qian X, Li T, Tian Z, Jin H, Huang C. NF-κB1 p50 stabilizes HIF-1α protein through suppression of ATG7-dependent autophagy. Cell Death & Disease. 13: 1076. PMID 36575197 DOI: 10.1038/s41419-022-05521-1 |
0.308 |
|
| 2022 |
Xie Q, Hua X, Huang C, Liao X, Tian Z, Xu J, Zhao Y, Jiang G, Huang H, Huang C. SOX2 Promotes Invasion in Human Bladder Cancers through MMP2 Upregulation and FOXO1 Downregulation. International Journal of Molecular Sciences. 23. PMID 36293387 DOI: 10.3390/ijms232012532 |
0.328 |
|
| 2021 |
Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C. ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: e2104365. PMID 34786890 DOI: 10.1002/advs.202104365 |
0.56 |
|
| 2021 |
Zhu J, Lii Y, Chen C, Ma J, Sun W, Tian Z, Li J, Xu J, Liu CS, Zhang D, Huang C, Huang H. Corrigendum to "NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein" [Neoplasia 19 (2017) 672-683]. Neoplasia (New York, N.Y.). 23: 1179-1182. PMID 34731786 DOI: 10.1016/j.neo.2021.09.007 |
0.614 |
|
| 2020 |
Xu J, Yang R, Hua X, Huang M, Tian Z, Li J, Lam HY, Jiang G, Cohen M, Huang C. lncRNA SNHG1 Promotes Basal Bladder Cancer Invasion via Interaction with PP2A Catalytic Subunit and Induction of Autophagy. Molecular Therapy. Nucleic Acids. 21: 354-366. PMID 32650234 DOI: 10.1016/J.Omtn.2020.06.010 |
0.434 |
|
| 2020 |
Yang L, So JY, Skrypek N, Yang HH, Merchant AS, Nelson GW, Chen WD, Ishii H, Chen JM, Hu G, Achyut BR, Yoon EC, Han L, Huang C, Cam MC, et al. Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization. Cancer Research. PMID 32265226 DOI: 10.1158/0008-5472.Can-19-3339 |
0.383 |
|
| 2020 |
Jin H, Ma J, Xu J, Li H, Chang Y, Zang N, Tian Z, Wang X, Zhao N, Liu L, Chen C, Xie Q, Lu Y, Fang Z, Huang X, ... Huang C, et al. Oncogenic role of in human bladder cancer was mediated by its attenuating PHLPP2 expression and BECN1-dependent autophagy. Autophagy. 1-15. PMID 32116109 DOI: 10.1080/15548627.2020.1733262 |
0.465 |
|
| 2019 |
Yang R, Xu J, Hua X, Tian Z, Xie Q, Li J, Jiang G, Cohen M, Sun H, Huang C. Overexpressed miR-200a promotes bladder cancer invasion through direct regulating Dicer/miR-16/JNK2/MMP-2 axis. Oncogene. PMID 31772330 DOI: 10.1038/S41388-019-1120-Z |
0.326 |
|
| 2019 |
Ding J, Li J, Xue C, Wu K, Ouyang W, Zhang D, Yan Y, Huang C. Correction: Cycooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells. The Journal of Biological Chemistry. 294: 14165. PMID 31541029 DOI: 10.1074/Jbc.Aac119.010754 |
0.671 |
|
| 2019 |
Wang J, Zhang N, Peng M, Hua X, Huang C, Tian Z, Xie Q, Zhu J, Li J, Huang H, Huang C. p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation. Neoplasia (New York, N.Y.). 21: 908-920. PMID 31401412 DOI: 10.1016/J.Neo.2019.07.007 |
0.456 |
|
| 2019 |
Yan H, Ren S, Lin Q, Yu Y, Chen C, Hua X, Jin H, Lu Y, Zhang H, Xie Q, Huang C, Huang H. Inhibition of UBE2N-dependent CDK6 protein degradation by miR-934 promotes human bladder cancer cell growth. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900499RR. PMID 31373842 DOI: 10.1096/Fj.201900499Rr |
0.417 |
|
| 2019 |
Hua X, Huang M, Deng X, Xu J, Luo Y, Xie Q, Xu J, Tian Z, Li J, Zhu J, Huang C, Zhao QS, Huang H, Huang C. The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein. Cell Death and Differentiation. PMID 31243344 DOI: 10.1038/S41418-019-0377-7 |
0.397 |
|
| 2019 |
Jin H, Xue L, Mo L, Zhang D, Guo X, Xu J, Li J, Peng M, Zhao X, Zhong M, Xu D, Wu XR, Huang H, Huang C. Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. Cell Adhesion & Migration. 13: 236-248. PMID 31240993 DOI: 10.1080/19336918.2019.1633851 |
0.597 |
|
| 2019 |
Luo Y, Tian Z, Hua X, Huang M, Xu J, Li J, Huang H, Cohen M, Huang C. Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression. Cellular and Molecular Life Sciences : Cmls. PMID 31222373 DOI: 10.1007/S00018-019-03185-3 |
0.428 |
|
| 2019 |
Tian Z, Luo Y, Zhu J, Hua X, Xu J, Huang C, Jin H, Huang H, Huang C. Transcriptionally elevation of miR-494 by new ChlA-F compound via a HuR/JunB axis inhibits human bladder cancer cell invasion. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. PMID 31167152 DOI: 10.1016/J.Bbagrm.2019.05.007 |
0.348 |
|
| 2019 |
Sun W, Li S, Yu Y, Jin H, Xie Q, Hua X, Wang S, Tian Z, Zhang H, Jiang G, Huang C, Huang H. MicroRNA-3648 Is Upregulated to Suppress TCF21, Resulting in Promotion of Invasion and Metastasis of Human Bladder Cancer. Molecular Therapy. Nucleic Acids. 16: 519-530. PMID 31071528 DOI: 10.1016/J.Omtn.2019.04.006 |
0.321 |
|
| 2019 |
Zhu J, Tian Z, Li Y, Hua X, Zhang D, Li J, Jin H, Xu J, Chen W, Niu B, Wu XR, Comincini S, Huang H, Huang C. ATG7 Promotes Bladder Cancer Invasion via Autophagy-Mediated Increased ARHGDIB mRNA Stability. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1801927. PMID 31016112 DOI: 10.1002/Advs.201801927 |
0.644 |
|
| 2019 |
Xie Q, Chen C, Li H, Xu J, Wu L, Yu Y, Ren S, Li H, Hua X, Yan H, Rao D, Zhang H, Jin H, Huang H, Huang C. miR-3687 Overexpression Promotes Bladder Cancer Cell Growth by Inhibiting the Negative Effect of FOXP1 on Cyclin E2 Transcription. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30935821 DOI: 10.1016/J.Ymthe.2019.03.006 |
0.413 |
|
| 2019 |
Zhu J, Li Y, Luo Y, Xu J, Liufu H, Tian Z, Huang C, Li J, Huang C. A Feedback Loop Formed by ATG7/Autophagy, FOXO3a/miR-145 and PD-L1 Regulates Stem-Like Properties and Invasion in Human Bladder Cancer. Cancers. 11. PMID 30871066 DOI: 10.3390/Cancers11030349 |
0.324 |
|
| 2019 |
Huang C, Liao X, Jin H, Xie F, Zheng F, Li J, Zhou C, Jiang G, Wu XR, Huang C. MEG3, as a Competing Endogenous RNA, Binds with miR-27a to Promote PHLPP2 Protein Translation and Impairs Bladder Cancer Invasion. Molecular Therapy. Nucleic Acids. 16: 51-62. PMID 30826633 DOI: 10.1016/J.Omtn.2019.01.014 |
0.412 |
|
| 2019 |
Peng M, Wang J, Tian Z, Zhang D, Jin H, Liu C, Xu J, Li J, Hua X, Xu J, Huang C, Huang C. Autophagy-Mediated Mir6981 Degradation Exhibits Cdkn1b Promotion of PHLPP1 Protein Translation. Autophagy. PMID 30821592 DOI: 10.1080/15548627.2019.1586254 |
0.622 |
|
| 2019 |
Jiang G, Huang C, Liao X, Li J, Wu XR, Zeng F, Huang C. The RING domain in the anti-apoptotic protein XIAP stabilizes c-Myc protein and preserves anchorage-independent growth of bladder cancer cells. The Journal of Biological Chemistry. PMID 30819803 DOI: 10.1074/Jbc.Ra118.005621 |
0.428 |
|
| 2019 |
Zhu J, Huang G, Hua X, Li Y, Yan H, Che X, Tian Z, Liufu H, Huang C, Li J, Xu J, Dai W, Huang H, Huang C. CD44s is a crucial ATG7 downstream regulator for stem-like property, invasion, and lung metastasis of human bladder cancer (BC) cells. Oncogene. PMID 30635654 DOI: 10.1038/S41388-018-0664-7 |
0.333 |
|
| 2019 |
Hua X, Xu J, Huang C, Li J, Tian Z, Huang H. Abstract 785: The inhibitory effect of compound ChlA-F onhuman bladder cancer cell invasion can be attributed to its blockage of SOX2 protein Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-785 |
0.342 |
|
| 2019 |
Tian Z, Hua X, Xu J, Zhu J, li J, Huang C. Abstract 4340: A novel fluoride (ChlA-F) transcriptionally upregulates miR494 via a HuR/JunB axis to inhibit cell invasion in human bladder cancers Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4340 |
0.342 |
|
| 2019 |
He F, Zhang F, Liu Y, Shapiro E, Lepor H, Tang M, Huang C, Wu X. Mp51-13 Hyper-Phosphorylation Of Pten Is A Principal Mechanism Of Pten Inactivation In Human Bladder Cancer The Journal of Urology. 201. DOI: 10.1097/01.Ju.0000556486.12569.Ae |
0.334 |
|
| 2018 |
Guo X, Huang H, Jin H, Xu J, Risal S, Li J, Li X, Yan H, Zeng X, Xue L, Chen C, Huang C. ISO, via Upregulating MiR-137 Transcription, Inhibits GSK3β-HSP70-MMP-2 Axis, Resulting in Attenuating Urothelial Cancer Invasion. Molecular Therapy. Nucleic Acids. 12: 337-349. PMID 30195772 DOI: 10.1016/J.Omtn.2018.05.017 |
0.353 |
|
| 2018 |
Hua X, Xu J, Deng X, Xu J, Li J, Zhu DQ, Zhu J, Jin H, Tian Z, Huang H, Zhao QS, Huang C. New Compound ChlA-F Induces Autophagy-dependent Anti-cancer Effect via Upregulating Sestrin-2 in Human Bladder Cancer. Cancer Letters. PMID 30118841 DOI: 10.1016/J.Canlet.2018.08.013 |
0.384 |
|
| 2018 |
Li X, Tian Z, Jin H, Xu J, Hua X, Yan H, Liufu H, Wang J, Li J, Zhu J, Huang H, Huang C. Decreased c-Myc mRNA Stability miR-141-3p/AUF1 Axis Is Crucial for p63α Inhibition of Cyclin D1 Transcription and Bladder Cancer Cell Tumorigenicity. Molecular and Cellular Biology. PMID 30104251 DOI: 10.1128/Mcb.00273-18 |
0.483 |
|
| 2018 |
Peng M, Wang J, Zhang D, Jin H, Li J, Wu XR, Huang C. PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein. Oncogene. PMID 29930380 DOI: 10.1038/S41388-018-0374-1 |
0.679 |
|
| 2018 |
Jin H, Sun W, Zhang Y, Yan H, Liufu H, Wang S, Chen C, Gu J, Hua X, Zhou L, Jiang G, Rao D, Xie Q, Huang H, Huang C. MicroRNA-411 Downregulation Enhances Tumor Growth by Upregulating MLLT11 Expression in Human Bladder Cancer. Molecular Therapy. Nucleic Acids. 11: 312-322. PMID 29858066 DOI: 10.1016/J.Omtn.2018.03.003 |
0.334 |
|
| 2018 |
Han F, Liu WB, Shi XY, Yang JT, Zhang X, Li ZM, Jiang X, Yin L, Li JJ, Huang CS, Cao J, Liu JY. SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer. Ebiomedicine. PMID 29739711 DOI: 10.1016/J.Ebiom.2018.04.026 |
0.36 |
|
| 2018 |
Jiang G, Huang C, Li J, Huang H, Wang J, Li Y, Xie F, Jin H, Zhu J, Huang C. Transcriptional and Posttranscriptional Upregulation of p27 Mediates Growth Inhibition of Isorhapontigenin (ISO) on Human Bladder Cancer Cells. Carcinogenesis. PMID 29409027 DOI: 10.1093/Carcin/Bgy015 |
0.458 |
|
| 2018 |
Zhu Y, Murphy A, Kluz T, Li B, Costa M, Huang C, Sun H. Abstract 5857: Isorhapontigenin inhibits triple-negative breast cancer via activating NRF2-mediated pathway Cancer Research. 78: 5857-5857. DOI: 10.1158/1538-7445.Am2018-5857 |
0.385 |
|
| 2018 |
Hua X, Che X, Xu J, Huang C, Huang G, Dai W. Abstract 4383: CD44s is a crucial ATG7 downstream regulator for formation of sphere, a key stem-like property, invasion and lung metastasis of human bladder cancer/BC cells Cancer Research. 78: 4383-4383. DOI: 10.1158/1538-7445.Am2018-4383 |
0.337 |
|
| 2018 |
Hua X, Xu J, Jin H, Huang C. Abstract 107: Interaction of BIR domain of XIAP with Sp1/E2F1 activates MMP2 and bladder cancer cell invasion by inhibiting src protein translation Tumor Biology. DOI: 10.1158/1538-7445.Am2018-107 |
0.379 |
|
| 2018 |
Tian Z, Jin H, Li J, Huang C, Huang C. Abstract 1062: Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer Tumor Biology. DOI: 10.1158/1538-7445.Am2018-1062 |
0.315 |
|
| 2018 |
Hua X, Jin H, Huang H, Li J, Huang C. MP65-17 MICRORNA-411 DOWNREGULATION PROMOTES TUMORIGENESIS AND INHIBITS CHEMOTHERAPY SENSITIVITY BY UPREGULATING MLLT11 EXPRESSION IN HUMAN BLADDER CANCER. Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2083 |
0.398 |
|
| 2017 |
Yu Y, Jin H, Xu J, Gu J, Li X, Xie Q, Huang H, Li J, Tian Z, Jiang G, Chen C, He F, Wu XR, Huang C. XIAP Overexpression Promotes Bladder Cancer Invasion in Vitro and Lung Metastasis in Vivo via Enhancing Nucleolin-Mediated Rho-GDIβ mRNA Stability. International Journal of Cancer. PMID 29250796 DOI: 10.1002/Ijc.31223 |
0.425 |
|
| 2017 |
Liao X, Huang C, Zhang D, Wang J, Li J, Jin H, Huang C. Mitochondrial Catalase Induces Cells Transformation Through Nucleolin-dependent Cox-2 mRNA Stabilization. Free Radical Biology & Medicine. PMID 29097213 DOI: 10.1016/J.Freeradbiomed.2017.10.387 |
0.635 |
|
| 2017 |
Huang H, Jin H, Zhao H, Wang J, Li X, Yan H, Wang S, Guo X, Xue L, Li J, Peng M, Wang A, Zhu J, Wu XR, Chen C, ... Huang C, et al. RhoGDIβ Promotes Sp1/MMP-2 Expression and Bladder Cancer Invasion Through Perturbing miR-200c-Targeted JNK2 Protein Translation. Molecular Oncology. PMID 28846829 DOI: 10.1002/1878-0261.12132 |
0.374 |
|
| 2017 |
Jin H, Xie Q, Guo X, Xu J, Wang A, Li J, Zhu J, Wu XR, Huang H, Huang C. p63α protein upregulates heat shock protein 70 expression via E2F1 transcription factor 1, promoting Wasf3/Wave3/MMP9 signaling and bladder cancer invasion. The Journal of Biological Chemistry. PMID 28794159 DOI: 10.1074/Jbc.M117.792010 |
0.437 |
|
| 2017 |
Zhu J, Li Y, Chen C, Ma J, Sun W, Tian Z, Li J, Xu J, Liu CS, Zhang D, Huang C, Huang H. NF-κB p65 Overexpression Promotes Bladder Cancer Cell Migration via FBW7-Mediated Degradation of RhoGDIα Protein. Neoplasia (New York, N.Y.). 19: 672-683. PMID 28772241 DOI: 10.1016/J.Neo.2017.06.002 |
0.649 |
|
| 2017 |
Zhu J, Li Y, Tian Z, Hua X, Gu J, Li J, Liu C, Jin H, Wang Y, Jiang G, Huang H, Huang C. ATG7 Overexpression Is Crucial for Tumorigenic Growth of Bladder Cancer In Vitro and In Vivo by Targeting the ETS2/miRNA196b/FOXO1/p27 Axis. Molecular Therapy. Nucleic Acids. 7: 299-313. PMID 28624205 DOI: 10.1016/J.Omtn.2017.04.012 |
0.478 |
|
| 2017 |
Jiang G, Huang C, Li J, Huang H, Jin H, Zhu J, Wu XR, Huang C. Role of STAT3 and FOXO1 in the divergent therapeutic responses of non-metastatic and metastatic bladder cancer cells to miR-145. Molecular Cancer Therapeutics. PMID 28223425 DOI: 10.1158/1535-7163.Mct-16-0631 |
0.337 |
|
| 2017 |
Huang C, Zeng X, Jiang G, Liao X, Liu C, Li J, Jin H, Zhu J, Sun H, Wu XR, Huang C. XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell. Journal of Hematology & Oncology. 10: 6. PMID 28057023 DOI: 10.1186/S13045-016-0376-9 |
0.405 |
|
| 2017 |
Liao X, Huang C, Li J, Huang C. Abstract 533: XIAP BIR domain suppresses miR-200a expression and subsequently promotes EGFR protein translation and anchorage-independent growth of bladder cancer cell Cancer Research. 77: 533-533. DOI: 10.1158/1538-7445.Am2017-533 |
0.362 |
|
| 2017 |
Li Y, Zhu J, Li J, Huang C. Abstract 526: NFκB p65 overexpression promotes bladder cancer migration via FBW7-mediated degradation of RhoGDIα protein Cancer Research. 77: 526-526. DOI: 10.1158/1538-7445.Am2017-526 |
0.469 |
|
| 2017 |
Zhu J, Li Y, Huang C, Huang H. Abstract 3310: Atg7 overexpression promotes bladder cancer invasionviaautophagic removal of AUF1 protein and subsequently increased RhoGDI2 mRNA stabilityin vitroandin vivo Cancer Research. 77: 3310-3310. DOI: 10.1158/1538-7445.Am2017-3310 |
0.471 |
|
| 2017 |
Huang C, Liao X, Li J, Huang C. Abstract 1898: MEG3 as a competing endogenous RNA binds with miR-27a to promote PHLPP2 protein translation, and consequently impairs bladder cancer invasion Cancer Research. 77: 1898-1898. DOI: 10.1158/1538-7445.Am2017-1898 |
0.303 |
|
| 2017 |
Wang X, Zhang F, Lepor H, Tang M, Huang C, Wu X. Mp98-16 Down-Regulation Of Pyruvate Kinase 2 By Rnai And Small Molecule Inhibitor Overcomes Cisplatin Resistance Of Bladder Cancer Cells In Vitro And In Vivo The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.3081 |
0.385 |
|
| 2017 |
Huang C, Liao X, Li J, Wu X, Huang C. Mp98-08 Long Non-Coding Rna, Meg3, Suppresses Bladder Cancer Invasion By Competitively Binding Mir-27A And Promoting Protein Translation Of Phlpp2 Tumor Suppressor The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.3073 |
0.306 |
|
| 2017 |
Zhu J, Li Y, Huang C, Wu X. Mp34-12 Overexpression Of Autophagy-Related Gene Atg7 Promotes Bladder Cancer Invasion Via Autophagic Removal Of Pre-Mrna Processing Protein Auf1 And Increased Stability Of Rhogdi? Mrna In Vitro And In Vivo The Journal of Urology. 197. DOI: 10.1016/J.Juro.2017.02.1029 |
0.361 |
|
| 2016 |
Zhang R, Che X, Zhang J, Li Y, Li J, Deng X, Zhu J, Jin H, Zhao Q, Huang C. Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation. Oncotarget. PMID 27556506 DOI: 10.18632/Oncotarget.11440 |
0.461 |
|
| 2016 |
Huang H, Zhu J, Li Y, Zhang L, Gu J, Xie Q, Jin H, Che X, Li J, Huang C, Chen LC, Lyu J, Gao J, Huang C. Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells. Autophagy. 0. PMID 27467530 DOI: 10.1080/15548627.2016.1196313 |
0.445 |
|
| 2016 |
Liang Y, Zhu J, Huang H, Xiang D, Li Y, Zhang D, Li J, Wang Y, Jin H, Jiang G, Liu Z, Huang C. SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers. Autophagy. 0. PMID 27171279 DOI: 10.1080/15548627.2016.1179403 |
0.668 |
|
| 2016 |
Zhou H, He F, Mendelsohn CL, Tang MS, Huang C, Wu XR. FGFR3b Extracellular Loop Mutation Lacks Tumorigenicity In Vivo but Collaborates with p53/pRB Deficiency to Induce High-grade Papillary Urothelial Carcinoma. Scientific Reports. 6: 25596. PMID 27157475 DOI: 10.1038/Srep25596 |
0.373 |
|
| 2016 |
Xu J, Wang Y, Hua X, Xu J, Tian Z, Jin H, Li J, Wu XR, Huang C. Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100). Oncotarget. PMID 27095572 DOI: 10.18632/Oncotarget.8746 |
0.454 |
|
| 2016 |
Jiang G, Wu AD, Huang C, Gu J, Zhang L, Huang H, Liao X, Li J, Zhang D, Zeng X, Jin H, Huang H, Huang C. Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis. Cancer Prevention Research (Philadelphia, Pa.). PMID 27080594 DOI: 10.1158/1940-6207.CAPR-15-0338 |
0.601 |
|
| 2016 |
Huang C, Zhang P, Zhang D, Weng X. The Prognostic Implication of Slug in All Tumor Patients-A Systematic Meta Analysis. European Journal of Clinical Investigation. PMID 26919035 DOI: 10.1111/eci.12608 |
0.5 |
|
| 2016 |
Xie Q, Guo X, Gu J, Zhang L, Jin H, Huang H, Li J, Huang C. p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation. Oncotarget. PMID 26918608 DOI: 10.18632/oncotarget.7674 |
0.357 |
|
| 2016 |
Xia X, Huang C, Zhang D, Zhang Y, Xue S, Wang X, Zhang Q, Guo L. Molecular cloning, characterization, and the response of Cu/Zn superoxide dismutase and catalase to PBDE-47 and -209 from the freshwater bivalve Anodonta woodiana. Fish & Shellfish Immunology. PMID 26915310 DOI: 10.1016/j.fsi.2016.02.025 |
0.508 |
|
| 2016 |
Zeng X, Xu Z, Gu J, Huang H, Gao G, Zhang X, Li J, Jin H, Jiang G, Sun H, Huang C. Induction of miR-137 by isorhapontigenin (ISO) direct targeted Sp1 protein translation and mediated its anti-cancer activity both in vitro and in vivo. Molecular Cancer Therapeutics. PMID 26832795 DOI: 10.1158/1535-7163.Mct-15-0606 |
0.434 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Huang C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.516 |
|
| 2016 |
Li ZL, Nan J, Huang C, Liang B, Liu WZ, Cheng HY, Zhang C, Zhang D, Kong D, Kanamaru K, Kobayashi T, Wang AJ, Katayama A. Spatial Abundance and Distribution of Potential Microbes and Functional Genes Associated with Anaerobic Mineralization of Pentachlorophenol in a Cylindrical Reactor. Scientific Reports. 6: 19015. PMID 26750760 DOI: 10.1038/srep19015 |
0.47 |
|
| 2016 |
He F, Liu Y, Lepor H, Tang M, Huang C, Wu X. MP45-05 UROTHELIUM-SPECIFIC AND TEMPORALLY CONTROLLED BI-ALLELIC INACTIVATION OF BOTH PTEN AND P53 TRIGGERS BASAL-SUBTYPE MUSCLE-INVASIVE BLADDER CANCER Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.282 |
0.458 |
|
| 2015 |
Huang CL, Zhang W, Ni ZY, Zuo T, Zhou M, Xu J, Yang ZF, Li L, Xiao J, Zhang DY. Efficacy of video-assisted thoracoscopic surgery for 29 patients with tuberculosis-destroyed lung. International Journal of Clinical and Experimental Medicine. 8: 18391-8. PMID 26770443 |
0.44 |
|
| 2015 |
Ma X, Huang D, Zhao W, Sun L, Xiong H, Zhang Y, Jin M, Zhang D, Huang C, Wang H, Zhang W, Sun N, He L, Tang J. Clinical characteristics and prognosis of childhood rhabdomyosarcoma: a ten-year retrospective multicenter study. International Journal of Clinical and Experimental Medicine. 8: 17196-205. PMID 26770312 |
0.45 |
|
| 2015 |
Wang Y, Xu J, Gao G, Li J, Huang H, Jin H, Zhu J, Che X, Huang C. Tumor-suppressor NFκB2 p100 interacts with ERK2 and stabilizes PTEN mRNA via inhibition of miR-494. Oncogene. PMID 26686085 DOI: 10.1038/Onc.2015.470 |
0.472 |
|
| 2015 |
Xu Z, Zeng X, Xu J, Xu D, Li J, Jin H, Jiang G, Han X, Huang C. Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis. Neuro-Oncology. PMID 26681767 DOI: 10.1093/Neuonc/Nov298 |
0.33 |
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| 2015 |
Du P, Zhao H, Li H, Zhang D, Huang CH, Deng M, Liu C, Cao H. Transformation, products, and pathways of chlorophenols via electro-enzymatic catalysis: How to control toxic intermediate products. Chemosphere. 144: 1674-1681. PMID 26519798 DOI: 10.1016/J.Chemosphere.2015.10.038 |
0.479 |
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| 2015 |
Gao MK, Chen YM, Liu Q, Huang C, Li ZY, Zhang DH. Three-Dimensional Path Planning and Guidance of Leg Vascular Based on Improved Ant Colony Algorithm in Augmented Reality. Journal of Medical Systems. 39: 315. PMID 26319273 DOI: 10.1007/s10916-015-0315-2 |
0.441 |
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| 2015 |
Liu WB, Han F, Jiang X, Chen HQ, Zhao H, Liu Y, Li YH, Huang C, Cao J, Liu JY. TMEM196 acts as a novel functional tumour suppressor inactivated by DNA methylation and is a potential prognostic biomarker in lung cancer. Oncotarget. PMID 26056045 DOI: 10.18632/Oncotarget.4237 |
0.381 |
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| 2015 |
He F, Melamed J, Tang MS, Huang C, Wu XR. Oncogenic HRAS Activates Epithelial-to-Mesenchymal Transition and Confers Stemness to p53-Deficient Urothelial Cells to Drive Muscle Invasion of Basal Subtype Carcinomas. Cancer Research. 75: 2017-28. PMID 25795707 DOI: 10.1158/0008-5472.Can-14-3067 |
0.388 |
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| 2015 |
Zhang D, Huang C, Xin W, Ma X, Zhang W, Zhang T, Du G. Preclinical pharmacokinetic evaluation and metabolites identification of methyl salicylate-2-O-β-d-lactoside in rats using LC-MS/MS and Q-TOF-MS methods. Journal of Pharmaceutical and Biomedical Analysis. 109: 1-10. PMID 25746501 DOI: 10.1016/j.jpba.2015.02.022 |
0.452 |
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| 2015 |
Zhang D, Liang Y, Xie Q, Gao G, Wei J, Huang H, Li J, Gao J, Huang C. A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability. The Journal of Biological Chemistry. 290: 4784-800. PMID 25561743 DOI: 10.1074/Jbc.M114.598219 |
0.647 |
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| 2015 |
Jin H, Yu Y, Hu Y, Lu C, Li J, Gu J, Zhang L, Huang H, Zhang D, Wu XR, Gao J, Huang C. Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines. Oncotarget. 6: 522-36. PMID 25402510 DOI: 10.18632/Oncotarget.2680 |
0.638 |
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| 2015 |
Jiang S, Xiang D, Chen Q, Goodlin-Fahncke W, Huang C, Yang S, Zhang D, Zhao A. Public support of community corrections in China. International Journal of Offender Therapy and Comparative Criminology. 59: 772-89. PMID 24406472 DOI: 10.1177/0306624X13518381 |
0.438 |
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| 2015 |
Jin H, Li J, Huang C. Abstract 5107: Divergent behaviors and underlying mechanisms of cell migration and invasion in non-metastatic T24 and its metastatic derivative T24T bladder cancer cell lines Cancer Research. 75: 5107-5107. DOI: 10.1158/1538-7445.Am2015-5107 |
0.428 |
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| 2015 |
Xue L, Jiang G, Li J, Huang C. Abstract 5104: Isorhapontigenin (ISO) inhibits cancer invasion by enhancing FOXO1 transcription through targeting STAT1 phosphorylation at Tyr701 Cancer Research. 75: 5104-5104. DOI: 10.1158/1538-7445.Am2015-5104 |
0.39 |
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| 2015 |
An J, Zhang D, Huang C. Abstract 5103: Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration Cancer Research. 75: 5103-5103. DOI: 10.1158/1538-7445.Am2015-5103 |
0.67 |
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| 2015 |
Huang C, Zhu J, Li J. Abstract 4641: Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the Cheliensisin A (Chel A) inhibition of cell transformation Cancer Research. 75: 4641-4641. DOI: 10.1158/1538-7445.Am2015-4641 |
0.405 |
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| 2015 |
Zhou H, Liu Y, Lepor H, Tang M, Huang C, Wu X. MP36-20 DEFINING THE MOLECULAR DRIVERS OF HIGH-GRADE NON-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.748 |
0.403 |
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| 2015 |
He F, Liu Y, Melamed J, Lepor H, Tang M, Huang C, Wu X. MP36-19 RAS ACTIVATION SYNERGIZES WITH P53 DEFICIENCY TO PROVOKE EPITHELIAL-MESENCHYMAL TRANSITION FORMING CANCER PROGENITOR CELLS AND TRIGGERING BASAL SUBTYPE MUSCLE INVASIVE BLADDER CANCER Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.747 |
0.409 |
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| 2015 |
Jiang G, Li J, Tang M, Wu X, Huang C. Mp49-06 Stat3 Activation Status Contributes To The Differential Responses Of Metastatic And No-Metastatic Human Bladder Cancer Cells To Mir-145 Inhibition Of Anchorage-Independent Growth Through Regulation Of Foxo1 Expression The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.510 |
0.377 |
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| 2015 |
Zhou H, Huang K, Liu Y, He F, Wang X, Mo L, Lepor H, Tang M, Huang C, Wu X. MP45-19 UPREGULATION OF ISOENZYME M2 OF PYRUVATE KINASE IN BLADDER CANCER: IMPLICATION IN TUMOR INITIATION, PROGRESSION AND THERAPEUTIC TARGETING. Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1517 |
0.487 |
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| 2015 |
Zhang D, Huang C, Zeng X, Xu Z, Wu X, Tang M. Mp45-15 Mir-137 Inhibited Sp1 Protein Translation And Mediated Anti-Cancer Activity Of Isorhapontigenin (Iso) The Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1513 |
0.563 |
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| 2014 |
Li XH, Gong QM, Ling Y, Huang C, Yu DM, Gu LL, Liao XW, Zhang DH, Hu XQ, Han Y, Kong XF, Zhang XX. Inherent lipid metabolic dysfunction in glycogen storage disease IIIa. Biochemical and Biophysical Research Communications. 455: 90-7. PMID 25451272 DOI: 10.1016/j.bbrc.2014.10.096 |
0.503 |
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| 2014 |
Han F, Liu W, Jiang X, Shi X, Yin L, Ao L, Cui Z, Li Y, Huang C, Cao J, Liu J. SOX30, a novel epigenetic silenced tumor suppressor, promotes tumor cell apoptosis by transcriptional activating p53 in lung cancer. Oncogene. PMID 25435374 DOI: 10.1038/Onc.2014.370 |
0.416 |
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| 2014 |
Zhang D, Liu J, Mi X, Liang Y, Li J, Huang C. The N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axis. Cell Death & Disease. 5: e1535. PMID 25412313 DOI: 10.1038/Cddis.2014.496 |
0.625 |
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| 2014 |
Zhu J, Zhang J, Huang H, Li J, Yu Y, Jin H, Li Y, Deng X, Gao J, Zhao Q, Huang C. Crucial role of c-Jun phosphorylation at Ser63/73 mediated by PHLPP protein degradation in the cheliensisin a inhibition of cell transformation. Cancer Prevention Research (Philadelphia, Pa.). 7: 1270-81. PMID 25281487 DOI: 10.1158/1940-6207.Capr-14-0233 |
0.456 |
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| 2014 |
Zuo Z, Che X, Wang Y, Li B, Li J, Dai W, Lin CP, Huang C. High mobility group Box-1 inhibits cancer cell motility and metastasis by suppressing activation of transcription factor CREB and nWASP expression. Oncotarget. 5: 7458-70. PMID 25277185 DOI: 10.18632/Oncotarget.2150 |
0.477 |
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| 2014 |
Cao Z, Li X, Li J, Luo W, Huang C, Chen J. X-linked inhibitor of apoptosis protein (XIAP) lacking RING domain localizes to the nuclear and promotes cancer cell anchorage-independent growth by targeting the E2F1/Cyclin E axis. Oncotarget. 5: 7126-37. PMID 25216527 DOI: 10.18632/Oncotarget.2227 |
0.456 |
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| 2014 |
Jiang X, Guo X, Xu X, Teng M, Huang C, Zhang D, Zhang Q, Zhang J, Huang Y. Hypoxia regulates CD9-mediated keratinocyte migration via the P38/MAPK pathway. Scientific Reports. 4: 6304. PMID 25200404 DOI: 10.1038/srep06304 |
0.533 |
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| 2014 |
Wei J, Du K, Cai Q, Ma L, Jiao Z, Tan J, Xu Z, Li J, Luo W, Chen J, Gao J, Zhang D, Huang C. Lead induces COX-2 expression in glial cells in a NFAT-dependent, AP-1/NFκB-independent manner. Toxicology. 325: 67-73. PMID 25193092 DOI: 10.1016/J.Tox.2014.08.012 |
0.621 |
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| 2014 |
Fang Y, Wang Y, Wang Y, Meng Y, Zhu J, Jin H, Li J, Zhang D, Yu Y, Wu XR, Huang C. A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition. The Biochemical Journal. 463: 383-92. PMID 25121353 DOI: 10.1042/Bj20140103 |
0.657 |
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| 2014 |
Gao G, Chen L, Huang C. Anti-cancer drug discovery: update and comparisons in yeast, Drosophila, and zebrafish. Current Molecular Pharmacology. 7: 44-51. PMID 24993385 DOI: 10.2174/1874467207666140702113629 |
0.315 |
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| 2014 |
Gao G, Chen L, Li J, Zhang D, Fang Y, Huang H, Chen X, Huang C. Isorhapontigenin (ISO) inhibited cell transformation by inducing G0/G1 phase arrest via increasing MKP-1 mRNA Stability. Oncotarget. 5: 2664-77. PMID 24797581 DOI: 10.18632/Oncotarget.1872 |
0.657 |
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| 2014 |
Guo W, Liu J, Jian J, Li J, Wan Y, Huang C. IKK-β/NF-κB p65 mediates p27(Kip1) protein degradation in arsenite response. Biochemical and Biophysical Research Communications. 447: 563-8. PMID 24751519 DOI: 10.1016/J.Bbrc.2014.04.055 |
0.436 |
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| 2014 |
Zhang D, Wang Y, Liang Y, Zhang M, Wei J, Zheng X, Li F, Meng Y, Zhu NW, Li J, Wu XR, Huang C. Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration. Journal of Cell Science. 127: 2920-33. PMID 24727615 DOI: 10.1242/Jcs.148130 |
0.666 |
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| 2014 |
Xin W, Huang C, Zhang X, Xin S, Zhou Y, Ma X, Zhang D, Li Y, Zhou S, Zhang D, Zhang T, Du G. Methyl salicylate lactoside inhibits inflammatory response of fibroblast-like synoviocytes and joint destruction in collagen-induced arthritis in mice. British Journal of Pharmacology. 171: 3526-38. PMID 24712652 DOI: 10.1111/bph.12715 |
0.498 |
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| 2014 |
Yu H, He X, Xie W, Xiong J, Sheng H, Guo S, Huang C, Zhang D, Zhang K. Elastase LasB of Pseudomonas aeruginosa promotes biofilm formation partly through rhamnolipid-mediated regulation. Canadian Journal of Microbiology. 60: 227-35. PMID 24693981 DOI: 10.1139/cjm-2013-0667 |
0.528 |
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| 2014 |
Zhang J, Gao G, Chen L, Li J, Deng X, Zhao QS, Huang C. Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells. Oncotarget. 5: 841-52. PMID 24553354 DOI: 10.18632/Oncotarget.1780 |
0.478 |
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| 2014 |
Yang J, Hu L, Song T, Liu Y, Wu Q, Zhao L, Liu L, Zhao X, Zhang D, Huang C. Proteomic changes in female rat hippocampus following exposure to a terrified sound stress. Journal of Molecular Neuroscience : Mn. 53: 158-65. PMID 24510750 DOI: 10.1007/s12031-014-0242-6 |
0.497 |
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| 2014 |
Huang H, Ma L, Li J, Yu Y, Zhang D, Wei J, Jin H, Xu D, Gao J, Huang C. NF-κB1 inhibits c-Myc protein degradation through suppression of FBW7 expression. Oncotarget. 5: 493-505. PMID 24457827 DOI: 10.18632/Oncotarget.1643 |
0.654 |
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| 2014 |
Zhang R, Wang Y, Li J, Jin H, Song S, Huang C. The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade. The Journal of Biological Chemistry. 289: 6394-403. PMID 24451377 DOI: 10.1074/Jbc.M113.513960 |
0.48 |
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| 2014 |
Cao Z, Li X, Li J, Kang B, Chen J, Luo W, Huang C. SUMOylation of RhoGDIα is required for its repression of cyclin D1 expression and anchorage-independent growth of cancer cells. Molecular Oncology. 8: 285-96. PMID 24342356 DOI: 10.1016/J.Molonc.2013.11.006 |
0.485 |
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| 2014 |
Liu W, Li Z, Huang CH, Guo RT, Zhao L, Zhang D, Chen X, Wu Q, Zhu D. Structural and mutational studies on the unusual substrate specificity of meso-diaminopimelate dehydrogenase from Symbiobacterium thermophilum. Chembiochem : a European Journal of Chemical Biology. 15: 217-22. PMID 24339368 DOI: 10.1002/cbic.201300691 |
0.462 |
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| 2014 |
Jiang X, Huang XC, Ao L, Liu WB, Han F, Cao J, Zhang DY, Huang CS, Liu JY. Total alkaloids of Tripterygium hypoglaucum (levl.) Hutch inhibits tumor growth both in vitro and in vivo. Journal of Ethnopharmacology. 151: 292-8. PMID 24212079 DOI: 10.1016/J.Jep.2013.10.045 |
0.566 |
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| 2014 |
Hu L, Yang J, Song T, Hou N, Liu Y, Zhao X, Zhang D, Wang L, Wang T, Huang C. A new stress model, a scream sound, alters learning and monoamine levels in rat brain. Physiology & Behavior. 123: 105-13. PMID 24096192 DOI: 10.1016/j.physbeh.2013.09.010 |
0.45 |
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| 2014 |
Mo L, Deng F, Chachoua A, Huang WC, Ma HY, Lepor H, Huang C, Wu X. Novel role of X-linked inhibitor of apoptosis protein (XIAP) in bladder cancer cell invasion and prediction of disease progression. Journal of Clinical Oncology. 32. DOI: 10.1200/Jco.2014.32.15_Suppl.E15504 |
0.407 |
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| 2014 |
Zhou H, Huang W, Lepor H, Tang M, Huang C, Wu X. Mp34-10 Crosstalk Between Downstream Effectors Of Receptor Tyrosine Kinase/Ras Pathway Can Be Disrupted By Combinatorial Inhibition: Implication In Targeted Therapy The Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1023 |
0.437 |
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| 2014 |
He F, Huang W, Lepor H, Tang M, Huang C, Wu X. Mp34-09 C-Terminal Hyper-Phosphorylation Of Pten Is A Major Mechanism Of Pten Inactivation In Bladder Cancer: Implications In Tumor Suppression And Molecular Therapy The Journal of Urology. 191. DOI: 10.1016/J.Juro.2014.02.1022 |
0.436 |
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| 2013 |
Du K, Yu Y, Zhang D, Luo W, Huang H, Chen J, Gao J, Huang C. NFκB1 (p50) suppresses SOD2 expression by inhibiting FoxO3a transactivation in a miR190/PHLPP1/Akt-dependent axis. Molecular Biology of the Cell. 24: 3577-83. PMID 24068327 DOI: 10.1091/Mbc.E13-06-0343 |
0.646 |
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| 2013 |
Huang C, Yuan PG, Zhu HM, Peng Z, Zhang DZ. [Report of the Fourth Symposium on the Hotspots and Challenges in Research of Antiviral Therapy for Chronic Hepatitis B]. Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology. 21: 394-6. PMID 24052965 |
0.443 |
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| 2013 |
Zhang J, Gao G, Chen L, Deng X, Li J, Yu Y, Zhang D, Li F, Zhang M, Zhao Q, Huang C. Cheliensisin A inhibits EGF-induced cell transformation with stabilization of p53 protein via a hydrogen peroxide/Chk1-dependent axis. Cancer Prevention Research (Philadelphia, Pa.). 6: 949-58. PMID 23852422 DOI: 10.1158/1940-6207.Capr-13-0097 |
0.673 |
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| 2013 |
Fang Y, Cao Z, Hou Q, Ma C, Yao C, Li J, Wu XR, Huang C. Cyclin d1 downregulation contributes to anticancer effect of isorhapontigenin on human bladder cancer cells. Molecular Cancer Therapeutics. 12: 1492-503. PMID 23723126 DOI: 10.1158/1535-7163.Mct-12-0922 |
0.445 |
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| 2013 |
Cao Z, Zhang R, Li J, Huang H, Zhang D, Zhang J, Gao J, Chen J, Huang C. X-linked inhibitor of apoptosis protein (XIAP) regulation of cyclin D1 protein expression and cancer cell anchorage-independent growth via its E3 ligase-mediated protein phosphatase 2A/c-Jun axis. The Journal of Biological Chemistry. 288: 20238-47. PMID 23720779 DOI: 10.1074/Jbc.M112.448365 |
0.679 |
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| 2013 |
Che X, Liu J, Huang H, Mi X, Xia Q, Li J, Zhang D, Ke Q, Gao J, Huang C. p27 suppresses cyclooxygenase-2 expression by inhibiting p38β and p38δ-mediated CREB phosphorylation upon arsenite exposure. Biochimica Et Biophysica Acta. 1833: 2083-91. PMID 23639288 DOI: 10.1016/J.Bbamcr.2013.04.012 |
0.649 |
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| 2013 |
Yu Y, Li J, Wan Y, Lu J, Gao J, Huang C. GADD45α induction by nickel negatively regulates JNKs/p38 activation via promoting PP2Cα expression. Plos One. 8: e57185. PMID 23536762 DOI: 10.1371/Journal.Pone.0057185 |
0.488 |
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| 2013 |
Fang Y, Meng Y, Li J, Zhang D, Yu Y, Lepor H, Wu X, Huang C. 1133 P27Kip1 Down-Regulates Egfr Expression Via Inhibition Of Jnk/C-Jun Transactivation: A Novel Function Of P27Kip1 In Tumor Suppression Deficient In Metastatic Bladder Cancer Cells The Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.748 |
0.628 |
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| 2012 |
Zhang D, Li J, Zhang M, Gao G, Zuo Z, Yu Y, Zhu L, Gao J, Huang C. The requirement of c-Jun N-terminal kinase 2 in regulation of hypoxia-inducing factor-1α mRNA stability Journal of Biological Chemistry. 287: 34361-34371. PMID 22910906 DOI: 10.1074/Jbc.M112.365882 |
0.619 |
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| 2012 |
Fang Y, Yu Y, Hou Q, Zheng X, Zhang M, Zhang D, Li J, Wu XR, Huang C. The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP. The Journal of Biological Chemistry. 287: 35234-43. PMID 22896709 DOI: 10.1074/Jbc.M112.389494 |
0.68 |
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| 2012 |
Zhang J, Ouyang W, Li J, Zhang D, Yu Y, Wang Y, Li X, Huang C. Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability. Toxicology and Applied Pharmacology. 263: 218-24. PMID 22749963 DOI: 10.1016/J.Taap.2012.06.012 |
0.617 |
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| 2012 |
Liu J, Zhang D, Luo W, Yu J, Li J, Yu Y, Zhang X, Chen J, Wu XR, Huang C. E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration, but not for its RhoGDI binding activity. Plos One. 7: e35682. PMID 22532870 DOI: 10.1371/Journal.Pone.0035682 |
0.613 |
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| 2012 |
Zuo Z, Cai T, Li J, Zhang D, Yu Y, Huang C. Hexavalent chromium Cr(VI) up-regulates COX-2 expression through an NFκB/c-Jun/AP-1-dependent pathway. Environmental Health Perspectives. 120: 547-53. PMID 22472290 DOI: 10.1289/Ehp.1104179 |
0.572 |
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| 2012 |
Zuo Z, Ouyang W, Li J, Costa M, Huang C. Cyclooxygenase-2 (COX-2) mediates arsenite inhibition of UVB-induced cellular apoptosis in mouse epidermal Cl41 cells. Current Cancer Drug Targets. 12: 607-16. PMID 22463588 DOI: 10.2174/156800912801784802 |
0.461 |
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| 2012 |
Li F, Wang H, Li L, Huang C, Lin J, Zhu G, Chen Z, Wu N, Feng H. Superoxide plays critical roles in electrotaxis of fibrosarcoma cells via activation of ERK and reorganization of the cytoskeleton. Free Radical Biology & Medicine. 52: 1888-96. PMID 22406317 DOI: 10.1016/J.Freeradbiomed.2012.02.047 |
0.422 |
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| 2012 |
Yu J, Zhang D, Liu J, Li J, Yu Y, Wu XR, Huang C. RhoGDI SUMOylation at Lys-138 increases its binding activity to Rho GTPase and its inhibiting cancer cell motility. The Journal of Biological Chemistry. 287: 13752-60. PMID 22393046 DOI: 10.1074/Jbc.M111.337469 |
0.644 |
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| 2012 |
Zhou H, Huang HY, Shapiro E, Lepor H, Huang WC, Mohammadi M, Mohr I, Tang MS, Huang C, Wu XR. Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies. Carcinogenesis. 33: 770-80. PMID 22287562 DOI: 10.1093/Carcin/Bgs025 |
0.394 |
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| 2012 |
Yu Y, Li J, Wan Y, Gao J, Huang C. Abstract 5458: GADD45α nickel induction inhibits JNKs/p38 activity by promoting PP2Cα expression Cancer Research. 72: 5458-5458. DOI: 10.1158/1538-7445.Am2012-5458 |
0.471 |
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| 2012 |
Zhang J, Ouyang W, Li J, Yu Y, Li X, Huang C. Abstract 4703: SAHA downregulation of HuR expression is responsible for reduction of cyclin D1 mRNA stability and cell transformation by EGF in Cl41 cells Cancer Research. 72: 4703-4703. DOI: 10.1158/1538-7445.Am2012-4703 |
0.402 |
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| 2012 |
Yu Y, Liu J, Zhang D, Luo W, Yu J, Li J, Zhang X, Chen J, Huang C. Abstract 4312: E3 ligase activity of XIAP RING domain is required for XIAP-mediated cancer cell migration but not for its RhoGDI binding activity Cancer Research. 72: 4312-4312. DOI: 10.1158/1538-7445.Am2012-4312 |
0.627 |
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| 2012 |
Zhang D, Li J, Zhang M, Zuo Z, Yu Y, Huang C. Abstract 2208: JNK2 regulates thehif-1αmRNA stability in a nucleolin-dependent manner Cancer Research. 72: 2208-2208. DOI: 10.1158/1538-7445.Am2012-2208 |
0.597 |
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| 2011 |
Li F, Wang H, Huang C, Lin J, Zhu G, Hu R, Feng H. Hydrogen peroxide contributes to the manganese superoxide dismutase promotion of migration and invasion in glioma cells. Free Radical Research. 45: 1154-61. PMID 21749277 DOI: 10.3109/10715762.2011.604321 |
0.401 |
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| 2011 |
Cai T, Li X, Ding J, Luo W, Li J, Huang C. A cross-talk between NFAT and NF-κB pathways is crucial for nickel-induced COX-2 expression in Beas-2B cells. Current Cancer Drug Targets. 11: 548-59. PMID 21486220 DOI: 10.2174/156800911795656001 |
0.452 |
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| 2011 |
Liu J, Zhang D, Luo W, Yu Y, Yu J, Li J, Zhang X, Zhang B, Chen J, Wu XR, Rosas-Acosta G, Huang C. X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility via Rho GDP dissociation inhibitor (RhoGDI)-dependent regulation of the cytoskeleton. The Journal of Biological Chemistry. 286: 15630-40. PMID 21402697 DOI: 10.1074/Jbc.M110.176982 |
0.667 |
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| 2011 |
Cai T, Che H, Yao T, Chen Y, Huang C, Zhang W, Du K, Zhang J, Cao Y, Chen J, Luo W. Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 119: 169-77. PMID 20937724 DOI: 10.1093/Toxsci/Kfq308 |
0.383 |
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| 2011 |
Guo W, Yang Z, Xia Q, Liu J, Yu Y, Li J, Zuo Z, Zhang D, Li X, Shi X, Huang C. Arsenite stabilizes HIF-1α protein through p85α-mediated up-regulation of inducible Hsp70 protein expression. Cellular and Molecular Life Sciences : Cmls. 68: 475-88. PMID 20835880 DOI: 10.1007/S00018-010-0459-7 |
0.652 |
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| 2011 |
Song L, Gao M, Dong W, Hu M, Li J, Shi X, Hao Y, Li Y, Huang C. Abstract 4211: p85alpha mediates p53 K370 acetylation by p300 and regulates its promoter-specific transactivity in the cellular UVB response Cancer Research. 71: 4211-4211. DOI: 10.1158/1538-7445.Am2011-4211 |
0.403 |
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| 2011 |
Yu Y, Liu J, Zhang D, Luo W, Yu J, Li J, Zhang X, Wu X, Acosta GR, Huang C. Abstract 2442: XIAP mediates cancer cell motility via RhoGDI-dependent regulation of cytoskeleton Cancer Research. 71: 2442-2442. DOI: 10.1158/1538-7445.Am2011-2442 |
0.645 |
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| 2011 |
Zhang D, Liu J, Yu Y, Zuo Z, Guo W, Zhao X, Li J, Hu Y, Yang W, Shi X, Huang C. Abstract 1330: p27 suppresses arsenite-induced Hsp27/Hsp70 expressions through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways Cancer Research. 71: 1330-1330. DOI: 10.1158/1538-7445.Am2011-1330 |
0.665 |
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| 2010 |
Liu J, Zhang D, Mi X, Xia Q, Yu Y, Zuo Z, Guo W, Zhao X, Cao J, Yang Q, Zhu A, Yang W, Shi X, Li J, Huang C. p27 suppresses arsenite-induced Hsp27/Hsp70 expression through inhibiting JNK2/c-Jun- and HSF-1-dependent pathways. The Journal of Biological Chemistry. 285: 26058-65. PMID 20566634 DOI: 10.1074/Jbc.M110.100271 |
0.66 |
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| 2010 |
Luo W, Li J, Zhang D, Cai T, Song L, Yin XM, Desai D, Amin S, Chen J, Huang C. Bid mediates anti-apoptotic COX-2 induction through the IKKbeta/NFkappaB pathway due to 5-MCDE exposure. Current Cancer Drug Targets. 10: 96-106. PMID 20088789 DOI: 10.2174/156800910790980160 |
0.644 |
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| 2010 |
Song L, Dong W, Gao M, Li J, Hu M, Guo N, Huang C. A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression. Biochimica Et Biophysica Acta. 1803: 323-32. PMID 20080131 DOI: 10.1016/J.Bbamcr.2010.01.006 |
0.447 |
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| 2010 |
Zhang D, Li J, Costa M, Gao J, Huang C. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70. Cancer Research. 70: 813-23. PMID 20068160 DOI: 10.1158/0008-5472.Can-09-0448 |
0.612 |
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| 2010 |
Zhang D, Cai T, Li J, Costa M, Huang C. Abstract 4373: JNK1 participates in the VHL-independent HIF-1α degradation pathway by regulating Hsp90/Hsp70 turnover and the HDAC6-dependent chaperone activity Cancer Research. 70: 4373-4373. DOI: 10.1158/1538-7445.Am10-4373 |
0.643 |
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| 2010 |
Cai T, Zuo Z, Ding J, Zhang D, Li J, Huang C. Abstract 4371: PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells Cancer Research. 70: 4371-4371. DOI: 10.1158/1538-7445.Am10-4371 |
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Guo W, Zuo Z, Yang Z, Xia Q, Liu J, Li J, Zhang D, Shi X, Huang C. Abstract 4370: Arsenite stabilizes HIF-1α protein through p85α-mediated upregulation of inducible Hsp70 protein expression Cancer Research. 70: 4370-4370. DOI: 10.1158/1538-7445.Am10-4370 |
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Yang Z, Song L, Huang C. Gadd45 Proteins as Critical Signal Transducers Linking NF-κB to MAPK Cascades Current Cancer Drug Targets. 9: 915-930. PMID 20025601 DOI: 10.2174/156800909790192383 |
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Yu Y, Wan Y, Huang C. The biological functions of NF-kappaB1 (p50) and its potential as an anti-cancer target. Current Cancer Drug Targets. 9: 566-71. PMID 19519322 DOI: 10.2174/156800909788486759 |
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Ding J, Ning B, Huang Y, Zhang D, Li J, Chen CY, Huang C. PI3K/Akt/JNK/c-Jun signaling pathway is a mediator for arsenite-induced cyclin D1 expression and cell growth in human bronchial epithelial cells. Current Cancer Drug Targets. 9: 500-9. PMID 19519318 DOI: 10.2174/156800909788486740 |
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Ding J, He G, Gong W, Wen W, Sun W, Ning B, Huang S, Wu K, Huang C, Wu M, Xie W, Wang H. Effects of nickel on cyclin expression, cell cycle progression and cell proliferation in human pulmonary cells. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 18: 1720-9. PMID 19505905 DOI: 10.1158/1055-9965.Epi-09-0115 |
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Ding J, Huang Y, Ning B, Gong W, Li J, Wang H, Chen CY, Huang C. TNF-alpha induction by nickel compounds is specific through ERKs/AP-1-dependent pathway in human bronchial epithelial cells. Current Cancer Drug Targets. 9: 81-90. PMID 19200052 DOI: 10.2174/156800909787313995 |
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Zhang D, Li J, Gao J, Huang C. c-Jun/AP-1 pathway-mediated cyclin D1 expression participates in low dose arsenite-induced transformation in mouse epidermal JB6 Cl41 cells. Toxicology and Applied Pharmacology. 235: 18-24. PMID 19059425 DOI: 10.1016/J.Taap.2008.11.002 |
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Ouyang W, Zhang D, Li J, Verma UN, Costa M, Huang C. Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation. Journal of Cellular Physiology. 218: 205-14. PMID 18792914 DOI: 10.1002/Jcp.21590 |
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DU HJ, Tang N, Liu BC, Shi XL, Huang CS, Gao A, Shen FH, Ye M, You BR. [Benzo (a) pyrene-induced human embryo lung cell cycle alterations through positive regulation of mitogen-activated protein kinase signal pathways]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine]. 41: 277-80. PMID 17959047 |
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Shen F, Fan X, Liu B, Jia X, Gao A, Du H, Ye M, You B, Huang C, Shi X. Downregulation of cyclin D1-CDK4 protein in human embryonic lung fibroblasts (HELF) induced by silica is mediated through the ERK and JNK pathway. Cell Biology International. 32: 1284-92. PMID 18703151 DOI: 10.1016/J.Cellbi.2008.07.015 |
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Song L, Li J, Hu M, Huang C. Both IKKalpha and IKKbeta are implicated in the arsenite-induced AP-1 transactivation correlating with cell apoptosis through NF-kappaB activity-independent manner. Experimental Cell Research. 314: 2187-98. PMID 18508047 DOI: 10.1016/J.Yexcr.2008.04.002 |
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Jiao S, Liu B, Gao A, Ye M, Jia X, Zhang F, Liu H, Shi X, Huang C. Benzo(a)pyrene-caused increased G1-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts. Toxicology Letters. 178: 167-75. PMID 18448277 DOI: 10.1016/J.Toxlet.2008.03.012 |
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Zhang D, Li J, Song L, Ouyang W, Gao J, Huang C. A JNK1/AP-1-dependent, COX-2 induction is implicated in 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation through regulating cell cycle progression. Molecular Cancer Research : McR. 6: 165-74. PMID 18234971 DOI: 10.1158/1541-7786.Mcr-07-0181 |
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Luo W, Liu J, Li J, Zhang D, Liu M, Addo JK, Patil S, Zhang L, Yu J, Buolamwini JK, Chen J, Huang C. Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway. The Journal of Biological Chemistry. 283: 8624-33. PMID 18218619 DOI: 10.1074/Jbc.M707860200 |
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Ouyang W, Luo W, Zhang D, Jian J, Ma Q, Li J, Shi X, Chen J, Gao J, Huang C. PI-3K/Akt pathway-dependent cyclin D1 expression is responsible for arsenite-induced human keratinocyte transformation. Environmental Health Perspectives. 116: 1-6. PMID 18197291 DOI: 10.1289/Ehp.10403 |
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Li J, Zhang D, Stoner GD, Huang C. Differential effects of black raspberry and strawberry extracts on BaPDE-induced activation of transcription factors and their target genes. Molecular Carcinogenesis. 47: 286-94. PMID 18085529 DOI: 10.1002/Mc.20377 |
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Zhang X, Jin B, Huang C. The PI3K/Akt pathway and its downstream transcriptional factors as targets for chemoprevention. Current Cancer Drug Targets. 7: 305-16. PMID 17979625 DOI: 10.2174/156800907780809741 |
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Zhang K, Li N, Chen Z, Shao K, Zhou F, Zhang C, Mu X, Wan J, Li B, Feng X, Shi S, Xiong M, Cao K, Wang X, Huang C, et al. High expression of nuclear factor of activated T cells in Chinese primary non-small cell lung cancer tissues. International Journal of Biological Markers. 22: 221-225. PMID 17922467 DOI: 10.5301/Jbm.2008.5470 |
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Huang X, Dai J, Huang C, Zhang Q, Bhanot O, Pelle E. Deferoxamine synergistically enhances iron-mediated AP-1 activation: a showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase. Free Radical Research. 41: 1135-42. PMID 17886035 DOI: 10.1080/10715760701609061 |
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Ding J, Wu K, Zhang D, Luo W, Li J, Ouyang W, Song L, Huang C. Activation of both nuclear factor of activated T cells and inhibitor of nuclear factor-kappa B kinase beta-subunit-/nuclear factor-kappa B is critical for cyclooxygenase-2 induction by benzo[a]pyrene in human bronchial epithelial cells. Cancer Science. 98: 1323-9. PMID 17640307 DOI: 10.1111/J.1349-7006.2007.00530.X |
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Huang C, Zhang D, Li J, Tong Q, Stoner GD. Differential inhibition of UV-induced activation of NF kappa B and AP-1 by extracts from black raspberries, strawberries, and blueberries. Nutrition and Cancer. 58: 205-12. PMID 17640167 DOI: 10.1080/01635580701328453 |
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Tong C, Yin Z, Song Z, Dockendorff A, Huang C, Mariadason J, Flavell RA, Davis RJ, Augenlicht LH, Yang W. c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression. The American Journal of Pathology. 171: 297-303. PMID 17591974 DOI: 10.2353/Ajpath.2007.061036 |
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Stoner GD, Wang LS, Zikri N, Chen T, Hecht SS, Huang C, Sardo C, Lechner JF. Cancer prevention with freeze-dried berries and berry components. Seminars in Cancer Biology. 17: 403-10. PMID 17574861 DOI: 10.1016/J.Semcancer.2007.05.001 |
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Ouyang W, Hu Y, Li J, Ding M, Lu Y, Zhang D, Yan Y, Song L, Qu Q, Desai D, Amin S, Huang C. Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells. Carcinogenesis. 28: 2218-26. PMID 17522069 DOI: 10.1093/Carcin/Bgm115 |
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Ouyang W, Zhang D, Ma Q, Li J, Huang C. Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells. Environmental Health Perspectives. 115: 513-8. PMID 17450217 DOI: 10.1289/Ehp.9588 |
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Gao A, Liu B, Shi X, Jia X, Ye M, Jiao S, You B, Huang C. Phosphatidylinositol-3 kinase/Akt/p70S6K/AP-1 signaling pathway mediated benzo(a)pyrene-induced cell cycle alternation via cell cycle regulatory proteins in human embryo lung fibroblasts. Toxicology Letters. 170: 30-41. PMID 17383120 DOI: 10.1016/J.Toxlet.2007.02.008 |
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Song Z, Tong C, Liang J, Dockendorff A, Huang C, Augenlicht LH, Yang W. JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo. European Journal of Pharmacology. 560: 95-100. PMID 17292881 DOI: 10.1016/J.Ejphar.2007.01.020 |
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Song L, Li J, Ye J, Yu G, Ding J, Zhang D, Ouyang W, Dong Z, Kim SO, Huang C. p85alpha acts as a novel signal transducer for mediation of cellular apoptotic response to UV radiation. Molecular and Cellular Biology. 27: 2713-31. PMID 17242187 DOI: 10.1128/Mcb.00657-06 |
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Zhang D, Li J, Wu K, Ouyang W, Ding J, Liu ZG, Costa M, Huang C. JNK1, but not JNK2, is required for COX-2 induction by nickel compounds. Carcinogenesis. 28: 883-91. PMID 17065197 DOI: 10.1093/Carcin/Bgl186 |
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Ouyang W, Ma Q, Li J, Zhang D, Ding J, Huang Y, Xing MM, Huang C. Benzo[a]pyrene diol-epoxide (B[a]PDE) upregulates COX-2 expression through MAPKs/AP-1 and IKKbeta/NF-kappaB in mouse epidermal Cl41 cells. Molecular Carcinogenesis. 46: 32-41. PMID 16921490 DOI: 10.1002/Mc.20260 |
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Jiao S, Liu B, Shi X, Huang C, Gao A, Ye M, Jia X. [c-Jun NH2-terminal kinase and extracellular signal-regulated protein kinase signaling pathways in regulation of benzo(a)pyrene-induced c-Jun activation in human embryo lung fibroblasts]. Chinese Journal of Industrial Hygiene and Occupational Diseases. 25: 385-388. DOI: 10.3760/Cma.J.Issn.1001-9391.2007.07.001 |
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Song L, Li J, Zhang D, Liu ZG, Ye J, Zhan Q, Shen HM, Whiteman M, Huang C. IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response. The Journal of Cell Biology. 175: 607-17. PMID 17116751 DOI: 10.1083/Jcb.200602149 |
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Ding J, Zhang X, Li J, Song L, Ouyang W, Zhang D, Xue C, Costa M, Meléndez JA, Huang C. Nickel compounds render anti-apoptotic effect to human bronchial epithelial Beas-2B cells by induction of cyclooxygenase-2 through an IKKbeta/p65-dependent and IKKalpha- and p50-independent pathway. The Journal of Biological Chemistry. 281: 39022-32. PMID 16982623 DOI: 10.1074/Jbc.M604798200 |
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Tong Q, Zheng L, Li B, Wang D, Huang C, Matuschak GM, Li D. Hypoxia-induced mitogenic factor enhances angiogenesis by promoting proliferation and migration of endothelial cells. Experimental Cell Research. 312: 3559-69. PMID 16982054 DOI: 10.1016/J.Yexcr.2006.07.024 |
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Zhang D, Song L, Li J, Wu K, Huang C. Coordination of JNK1 and JNK2 is critical for GADD45alpha induction and its mediated cell apoptosis in arsenite responses. The Journal of Biological Chemistry. 281: 34113-23. PMID 16973625 DOI: 10.1074/Jbc.M602821200 |
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Tong Q, Zheng L, Lin L, Li B, Wang D, Huang C, Matuschak GM, Li D. Participation of the PI-3K/Akt-NF-kappa B signaling pathways in hypoxia-induced mitogenic factor-stimulated Flk-1 expression in endothelial cells. Respiratory Research. 7: 101. PMID 16872509 DOI: 10.1186/1465-9921-7-101 |
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Ding J, Li J, Xue C, Wu K, Ouyang W, Zhang D, Yan Y, Huang C. Cyclooxygenase-2 induction by arsenite is through a nuclear factor of activated T-cell-dependent pathway and plays an antiapoptotic role in Beas-2B cells. The Journal of Biological Chemistry. 281: 24405-13. PMID 16809336 DOI: 10.1074/Jbc.M600751200 |
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| 2006 |
Yan Y, Li J, Ouyang W, Ma Q, Hu Y, Zhang D, Ding J, Qu Q, Subbaramaiah K, Huang C. NFAT3 is specifically required for TNF-alpha-induced cyclooxygenase-2 (COX-2) expression and transformation of Cl41 cells. Journal of Cell Science. 119: 2985-94. PMID 16803872 DOI: 10.1242/Jcs.03014 |
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| 2006 |
Lu H, Li J, Zhang D, Stoner GD, Huang C. Molecular mechanisms involved in chemoprevention of black raspberry extracts: from transcription factors to their target genes. Nutrition and Cancer. 54: 69-78. PMID 16800774 DOI: 10.1207/S15327914Nc5401_8 |
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Zhang D, Lu H, Li J, Shi X, Huang C. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B. Molecular and Cellular Biochemistry. 293: 161-71. PMID 16786188 DOI: 10.1007/S11010-006-9238-Z |
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Li J, Lu H, Huang C. NFAT3 is required for EGF-induced COX-2 transcription, but neither iNOS transcription nor cell transformation in Cl 41 cells. Molecular and Cellular Biochemistry. 289: 73-82. PMID 16718377 DOI: 10.1007/S11010-006-9149-Z |
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Lu B, Wang L, Stehlik C, Medan D, Huang C, Hu S, Chen F, Shi X, Rojanasakul Y. Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 6785-93. PMID 16709838 DOI: 10.4049/Jimmunol.176.11.6785 |
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Ding J, Zhang R, Li J, Xue C, Huang C. Involvement of nuclear factor of activated T cells 3 (NFAT3) in cyclin D1 induction by B[a]PDE or B[a]PDE and ionizing radiation in mouse epidermal Cl 41 cells. Molecular and Cellular Biochemistry. 287: 117-25. PMID 16645724 DOI: 10.1007/S11010-005-9087-1 |
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Lu H, Ouyang W, Huang C. Inflammation, a key event in cancer development. Molecular Cancer Research : McR. 4: 221-33. PMID 16603636 DOI: 10.1158/1541-7786.Mcr-05-0261 |
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Gao A, Liu BC, Huang CS, Shi XL, Jia XW, You BR, Ye M. [ERK and JNK/AP-1 pathways involved in benzo(a)pyrene induced cell cycle changes in human embryo lung fibroblasts]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases. 24: 72-6. PMID 16600107 |
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Hecht SS, Huang C, Stoner GD, Li J, Kenney PM, Sturla SJ, Carmella SG. Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkappaB and AP-1 activity. Carcinogenesis. 27: 1617-26. PMID 16522666 DOI: 10.1093/Carcin/Bgi366 |
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Tong Q, Zheng L, Lin L, Li B, Wang D, Huang C, Li D. VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway. Respiratory Research. 7: 37. PMID 16512910 DOI: 10.1186/1465-9921-7-37 |
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Ke Q, Li J, Ding J, Ding M, Wang L, Liu B, Costa M, Huang C. Essential role of ROS-mediated NFAT activation in TNF-alpha induction by crystalline silica exposure. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L257-64. PMID 16489119 DOI: 10.1152/Ajplung.00007.2006 |
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Li J, Song L, Zhang D, Wei L, Huang C. Knockdown of NFAT3 blocked TPA-induced COX-2 and iNOS expression, and enhanced cell transformation in Cl41 cells. Journal of Cellular Biochemistry. 99: 1010-20. PMID 16475165 DOI: 10.1002/Jcb.20834 |
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Zhang R, Li J, Burns FJ, Huang C. Ionizing radiation synergistic induction of cyclooxygenase-2 with benzo[a]pyrene diol-epoxide through nuclear factor of activated T cells in mouse epidermal Cl 41 cells. Oncology Reports. 15: 721-7. PMID 16465436 DOI: 10.3892/Or.15.3.721 |
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Ding J, Li J, Chen J, Chen H, Ouyang W, Zhang R, Xue C, Zhang D, Amin S, Desai D, Huang C. Effects of polycyclic aromatic hydrocarbons (PAHs) on vascular endothelial growth factor induction through phosphatidylinositol 3-kinase/AP-1-dependent, HIF-1alpha-independent pathway. The Journal of Biological Chemistry. 281: 9093-100. PMID 16461351 DOI: 10.1074/Jbc.M510537200 |
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Huang C, Li J, Song L, Zhang D, Tong Q, Ding M, Bowman L, Aziz R, Stoner GD. Black raspberry extracts inhibit benzo(a)pyrene diol-epoxide-induced activator protein 1 activation and VEGF transcription by targeting the phosphotidylinositol 3-kinase/Akt pathway. Cancer Research. 66: 581-7. PMID 16397275 DOI: 10.1158/0008-5472.Can-05-1951 |
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Ouyang W, Li J, Ma Q, Huang C. Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells. Carcinogenesis. 27: 864-73. PMID 16387740 DOI: 10.1093/Carcin/Bgi321 |
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Ding M, Huang C, Lu Y, Bowman L, Castranova V, Vallyathan V. Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L291-7. PMID 16169898 DOI: 10.1152/Ajplung.00053.2005 |
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Shen F, Fan X, Liu B, Jia X, Du H, You B, Ye M, Huang C, Shi X. Overexpression of cyclin D1-CDK4 in silica-induced transformed cells is due to activation of ERKs, JNKs/AP-1 pathway. Toxicology Letters. 160: 185-95. PMID 16125882 DOI: 10.1016/J.Toxlet.2005.07.009 |
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Gao A, Liu B, Shen F, Du H, Huang C, Jia X, You B, Ye M. [Vitamin C reverses benzo (a) pyrene-induced cell cycle changes by E2F pathway]. Chinese Journal of Preventive Medicine. 40: 79-83. DOI: 10.3760/J:Issn:0253-9624.2006.02.002 |
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Gao A, Liu B, Huang C, Shi X, Jia X, You B, Ye M. [ERK and JNK/AP-1 pathways involved in benzo(a)pyrene induced cell cycle changes in human embryo lung fibroblasts]. Chinese Journal of Industrial Hygiene and Occupational Diseases. 24: 72-76. DOI: 10.3760/Cma.J.Issn.1001-9391.2006.02.003 |
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Lu H, Shi X, Costa M, Huang C. Carcinogenic effect of nickel compounds. Molecular and Cellular Biochemistry. 279: 45-67. PMID 16283514 DOI: 10.1007/S11010-005-8215-2 |
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Ouyang W, Li J, Shi X, Costa M, Huang C. Essential role of PI-3K, ERKs and calcium signal pathways in nickel-induced VEGF expression. Molecular and Cellular Biochemistry. 279: 35-43. PMID 16283513 DOI: 10.1007/S11010-005-8214-3 |
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Li J, Tong Q, Shi X, Costa M, Huang C. ERKs activation and calcium signaling are both required for VEGF induction by vanadium in mouse epidermal Cl41 cells. Molecular and Cellular Biochemistry. 279: 25-33. PMID 16283512 DOI: 10.1007/S11010-005-8212-5 |
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Ouyang W, Ma Q, Li J, Zhang D, Liu ZG, Rustgi AK, Huang C. Cyclin D1 induction through IκB kinase β/nuclear factor-κB pathway is responsible for arsenite-induced increased cell cycle G 1-S phase transition in human keratinocytes Cancer Research. 65: 9287-9293. PMID 16230390 DOI: 10.1158/0008-5472.Can-05-0469 |
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Wang J, Ouyang W, Li J, Wei L, Ma Q, Zhang Z, Tong Q, He J, Huang C. Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation. Cancer Research. 65: 6601-11. PMID 16061640 DOI: 10.1158/0008-5472.Can-04-4184 |
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Costa M, Davidson TL, Chen H, Ke Q, Zhang P, Yan Y, Huang C, Kluz T. Nickel carcinogenesis: epigenetics and hypoxia signaling. Mutation Research. 592: 79-88. PMID 16009382 DOI: 10.1016/J.Mrfmmm.2005.06.008 |
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Ma C, Bower KA, Lin H, Chen G, Huang C, Shi X, Luo J. The role of epidermal growth factor receptor in ethanol-mediated inhibition of activator protein-1 transactivation. Biochemical Pharmacology. 69: 1785-94. PMID 15878157 DOI: 10.1016/J.Bcp.2005.03.029 |
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Chen J, Yan Y, Li J, Ma Q, Stoner GD, Ye J, Huang C. Differential requirement of signal pathways for benzo[a]pyrene (B[a]P)-induced nitric oxide synthase (iNOS) in rat esophageal epithelial cells. Carcinogenesis. 26: 1035-43. PMID 15718251 DOI: 10.1093/Carcin/Bgi052 |
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Dai J, Huang C, Wu J, Yang C, Frenkel K, Huang X. Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. Toxicology. 203: 199-209. PMID 15363595 DOI: 10.1016/J.Tox.2004.06.009 |
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Li J, Chen H, Ke Q, Feng Z, Tang MS, Liu B, Amin S, Costa M, Huang C. Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells. Molecular Carcinogenesis. 40: 104-15. PMID 15170815 DOI: 10.1002/Mc.20020 |
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Li J, Chen H, Tang MS, Shi X, Amin S, Desai D, Costa M, Huang C. PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells. The Journal of Cell Biology. 165: 77-86. PMID 15067018 DOI: 10.1083/Jcb.20040100420090708C |
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Li J, Tang MS, Liu B, Shi X, Huang C. A critical role of PI-3K/Akt/JNKs pathway in benzo[a]pyrene diol-epoxide (B[a]PDE)-induced AP-1 transactivation in mouse epidermal Cl41 cells. Oncogene. 23: 3932-44. PMID 15021902 DOI: 10.1038/Sj.Onc.1207501 |
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Zhang Z, Gao N, He H, Huang C, Jiang BH, Jia L, Shi X. The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry. Molecular and Cellular Biochemistry. 255: 239-45. PMID 14971664 DOI: 10.1023/B:Mcbi.0000007279.28280.E5 |
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Zhang Z, Gao N, He H, Huang C, Luo J, Shi X. Vanadate activated Akt and promoted S phase entry. Molecular and Cellular Biochemistry. 255: 227-37. PMID 14971663 DOI: 10.1023/B:Mcbi.0000007278.27936.8B |
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Li J, Dokka S, Wang L, Shi X, Castranova V, Yan Y, Costa M, Huang C. Activation of aPKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells. Molecular and Cellular Biochemistry. 255: 217-25. PMID 14971662 DOI: 10.1023/B:Mcbi.0000007277.90298.24 |
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Huang C, Ke Q, Costa M, Shi X. Molecular mechanisms of arsenic carcinogenesis. Molecular and Cellular Biochemistry. 255: 57-66. PMID 14971646 DOI: 10.1023/B:Mcbi.0000007261.04684.78 |
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Li J, Davidson G, Huang Y, Jiang BH, Shi X, Costa M, Huang C. Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells. Cancer Research. 64: 94-101. PMID 14729612 DOI: 10.1158/0008-5472.Can-03-0737 |
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Ding M, Lu Y, Bowman L, Huang C, Leonard S, Wang L, Vallyathan V, Castranova V, Shi X. Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract. The Journal of Biological Chemistry. 279: 10670-6. PMID 14665633 DOI: 10.1074/Jbc.M311465200 |
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Zhang Z, Leonard SS, Huang C, Vallyathan V, Castranova V, Shi X. Role of reactive oxygen species and MAPKs in vanadate-induced G(2)/M phase arrest. Free Radical Biology & Medicine. 34: 1333-42. PMID 12726921 DOI: 10.1016/S0891-5849(03)00145-X |
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Wang L, Medan D, Mercer R, Overmiller D, Leornard S, Castranova V, Shi X, Ding M, Huang C, Rojanasakul Y. Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species. Journal of Cellular Physiology. 195: 99-107. PMID 12599213 DOI: 10.1002/Jcp.10232 |
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| 2003 |
Li J, Ma C, Huang Y, Luo J, Huang C. Differential requirement of EGF receptor and its tyrosine kinase for AP-1 transactivation induced by EGF and TPA. Oncogene. 22: 211-9. PMID 12527890 DOI: 10.1038/Sj.Onc.1206102 |
0.369 |
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| 2002 |
Wang L, Medan D, Mercer R, Shi X, Huang C, Castranova V, Ding M, Rojanasakul Y. Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in mice. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 21: 343-50. PMID 12510963 DOI: 10.1615/Jenvironpatholtoxicoloncol.V21.I4.30 |
0.327 |
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| 2002 |
Huang C, Huang Y, Li J, Hu W, Aziz R, Tang MS, Sun N, Cassady J, Stoner GD. Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts. Cancer Research. 62: 6857-63. PMID 12460899 |
0.323 |
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| 2002 |
Zhang Z, Chen F, Huang C, Shi X. Vanadate induces G2/M phase arrest in p53-deficient mouse embryo fibroblasts. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 21: 223-31. PMID 12435075 DOI: 10.1615/Jenvironpatholtoxicoloncol.V21.I3.30 |
0.39 |
|
| 2002 |
Huang Y, Davidson G, Li J, Yan Y, Chen F, Costa M, Chen LC, Huang C. Activation of nuclear factor-kappaB and not activator protein-1 in cellular response to nickel compounds. Environmental Health Perspectives. 110: 835-9. PMID 12426142 DOI: 10.1289/Ehp.02110S5835 |
0.41 |
|
| 2002 |
Huang C, Li J, Zhang Q, Huang X. Role of bioavailable iron in coal dust-induced activation of activator protein-1 and nuclear factor of activated T cells: difference between Pennsylvania and Utah coal dusts. American Journal of Respiratory Cell and Molecular Biology. 27: 568-74. PMID 12397016 DOI: 10.1165/Rcmb.4821 |
0.408 |
|
| 2002 |
Zhu Y, Wang M, Lin H, Huang C, Shi X, Luo J. Epidermal growth factor up-regulates the transcription of mouse lon homology ATP-dependent protease through extracellular signal-regulated protein kinase- and phosphatidylinositol-3-kinase-dependent pathways. Experimental Cell Research. 280: 97-106. PMID 12372343 DOI: 10.1006/Excr.2002.5621 |
0.465 |
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| 2002 |
Lu B, Wang L, Medan D, Toledo D, Huang C, Chen F, Shi X, Rojanasakul Y. Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kappaB and tumor necrosis factor-alpha in macrophages. American Journal of Physiology. Cell Physiology. 283: C831-8. PMID 12176740 DOI: 10.1152/Ajpcell.00045.2002 |
0.376 |
|
| 2002 |
Ding M, Li J, Leonard SS, Shi X, Costa M, Castranova V, Vallyathan V, Huang C. Differential role of hydrogen peroxide in UV-induced signal transduction. Molecular and Cellular Biochemistry. 234: 81-90. PMID 12162463 DOI: 10.1023/A:1015901232124 |
0.43 |
|
| 2002 |
Li J, Huang B, Shi X, Castranova V, Vallyathan V, Huang C. Involvement of hydrogen peroxide in asbestos-induced NFAT activation. Molecular and Cellular Biochemistry. 234: 161-8. PMID 12162429 |
0.344 |
|
| 2002 |
Zhang Z, He H, Chen F, Huang C, Shi X. MAPKs mediate S phase arrest induced by vanadate through a p53-dependent pathway in mouse epidermal C141 cells. Chemical Research in Toxicology. 15: 950-956. PMID 12119006 DOI: 10.1021/Tx0255018 |
0.425 |
|
| 2002 |
She QB, Huang C, Zhang Y, Dong Z. Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis. Molecular Carcinogenesis. 33: 244-50. PMID 11933078 DOI: 10.1002/Mc.10041 |
0.482 |
|
| 2002 |
Zhang Z, Huang C, Li J, Shi X. Vanadate-induced cell growth arrest is p53-dependent through activation of p21 in C141 cells. Journal of Inorganic Biochemistry. 89: 142-148. PMID 11931974 DOI: 10.1016/S0162-0134(01)00409-3 |
0.412 |
|
| 2002 |
Li J, Huang B, Shi X, Castranova V, Vallyathan V, Huang C. Involvement of hydrogen peroxide in asbestos-induced NFAT activation. Molecular and Cellular Biochemistry. 234: 161-168. DOI: 10.1023/A:1015962916195 |
0.451 |
|
| 2001 |
Berdyshev EV, Schmid PC, Krebsbach RJ, Hillard CJ, Huang C, Chen N, Dong Z, Schmid HH. Cannabinoid-receptor-independent cell signalling by N-acylethanolamines. The Biochemical Journal. 360: 67-75. PMID 11695993 DOI: 10.1042/0264-6021:3600067 |
0.393 |
|
| 2001 |
Huang C, Zhang Q, Li J, Shi X, Castranova V, Ju G, Costa M, Dong Z. Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo. Molecular and Cellular Biochemistry. 222: 141-7. PMID 11678596 DOI: 10.1023/A:1017953927347 |
0.445 |
|
| 2001 |
Huang C, Li J, Ding M, Costa M, Castranova V, Vallyathan V, Ju G, Shi X. Transactivation of RARE and GRE in the cellular response to arsenic. Molecular and Cellular Biochemistry. 222: 119-25. PMID 11678593 DOI: 10.1023/A:1017975610084 |
0.434 |
|
| 2001 |
Huang C, Li J, Ding M, Leonard SS, Wang L, Castranova V, Vallyathan V, Shi X. UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide. The Journal of Biological Chemistry. 276: 40234-40. PMID 11507090 DOI: 10.1074/Jbc.M103684200 |
0.352 |
|
| 2001 |
Zhang Z, Huang C, Li J, Leonard SS, Lanciotti R, Butterworth L, Shi X. Vanadate-induced cell growth regulation and the role of reactive oxygen species. Archives of Biochemistry and Biophysics. 392: 311-320. PMID 11488607 DOI: 10.1006/Abbi.2001.2464 |
0.438 |
|
| 2001 |
Dong Z, Nomura M, Huang C, Ma W. Effects of tea polyphenols on the signal transduction pathways. Advances in Experimental Medicine and Biology. 492: 55-67. PMID 11480675 DOI: 10.1007/978-1-4615-1283-7_6 |
0.372 |
|
| 2001 |
Huang C, Ding M, Li J, Leonard SS, Rojanasakul Y, Castranova V, Vallyathan V, Ju G, Shi X. Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide. The Journal of Biological Chemistry. 276: 22397-403. PMID 11292823 DOI: 10.1074/Jbc.M010828200 |
0.377 |
|
| 2001 |
Huang C, Ma WY, Ding M, Li J, Shi X, Castranova V, Vallyathan V, Bode AM, Dong Z. Involvement of sphingomyelinase in insulin-induced phosphatidylinositol 3-kinase activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1113-4. PMID 11292685 DOI: 10.1096/Fj.00-0520Fje |
0.338 |
|
| 2001 |
Ding M, Shi X, Lu Y, Huang C, Leonard S, Roberts J, Antonini J, Castranova V, Vallyathan V. Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells. Journal of Biological Chemistry. 276: 9108-9114. PMID 11096084 DOI: 10.1074/Jbc.M007666200 |
0.42 |
|
| 2001 |
Huang C, Li J, Ding M, Wang L, Shi X, Castranova V, Vallyathan V, Ju G, Costa M. Molecular and Cellular Biochemistry. 222: 29-34. DOI: 10.1023/A:1017974131948 |
0.431 |
|
| 2000 |
Dokka S, Toledo D, Wang L, Shi X, Huang C, Leonard S, Rojanasakul Y. Free radical-mediated transgene inactivation of macrophages by endotoxin American Journal of Physiology - Lung Cellular and Molecular Physiology. 279. PMID 11053023 DOI: 10.1152/Ajplung.2000.279.5.L878 |
0.352 |
|
| 2000 |
Nomura M, Ma WY, Huang C, Yang CS, Bowden GT, Miyamoto K, Dong Z. Inhibition of ultraviolet B-induced AP-1 activation by theaflavins from black tea. Molecular Carcinogenesis. 28: 148-55. PMID 10942531 DOI: 10.1002/1098-2744(200007)28:3<148::Aid-Mc3>3.0.Co;2-Q |
0.463 |
|
| 2000 |
Huang C, Zhang Z, Ding M, Li J, Ye J, Leonard SS, Shen HM, Butterworth L, Lu Y, Costa M, Rojanasakul Y, Castranova V, Vallyathan V, Shi X. Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis. The Journal of Biological Chemistry. 275: 32516-22. PMID 10922372 DOI: 10.1074/Jbc.M005366200 |
0.402 |
|
| 2000 |
Huang C, Mattjus P, Ma W, Rincon M, Chen NY, Brown RE, Dong Z. Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice. Journal of Biological Chemistry. 275: 9143-9149. PMID 10734048 DOI: 10.1074/Jbc.275.13.9143 |
0.392 |
|
| 2000 |
Huang C, Li J, Chen N, Ma W, Bowden GT, Dong Z. Inhibition of atypical PKC blocks ultraviolet-induced AP-1 activation by specifically inhibiting ERKs activation. Molecular Carcinogenesis. 27: 65-75. PMID 10657899 DOI: 10.1002/(Sici)1098-2744(200002)27:2<65::Aid-Mc2>3.0.Co;2-E |
0.443 |
|
| 1999 |
Huang C, Li J, Ma WY, Dong Z. JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate. The Journal of Biological Chemistry. 274: 29672-6. PMID 10514437 DOI: 10.1074/Jbc.274.42.29672 |
0.44 |
|
| 1999 |
Shi X, Dong Z, Huang C, Ma W, Liu K, Ye J, Chen F, Leonard SS, Ding M, Castranova V, Vallyathan V. The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-κB Molecular and Cellular Biochemistry. 194: 63-70. PMID 10391125 DOI: 10.1023/A:1006904904514 |
0.352 |
|
| 1999 |
Huang C, Ma W, Dong Z. The extracellular-signal-regulated protein kinases (Erks) are required for UV-induced AP-1 activation in JB6 cells. Oncogene. 18: 2828-2835. PMID 10362253 DOI: 10.1038/Sj.Onc.1202639 |
0.432 |
|
| 1999 |
Chen N, Ma W, Huang C, Dong Z. Translocation of Protein Kinase Cε and Protein Kinase Cδ to Membrane Is Required for Ultraviolet B-induced Activation of Mitogen-activated Protein Kinases and Apoptosis Journal of Biological Chemistry. 274: 15389-15394. PMID 10336426 DOI: 10.1074/Jbc.274.22.15389 |
0.436 |
|
| 1999 |
Huang C, Ma WY, Li J, Goranson A, Dong Z. Requirement of Erk, but not JNK, for arsenite-induced cell transformation. The Journal of Biological Chemistry. 274: 14595-601. PMID 10329651 DOI: 10.1074/Jbc.274.21.14595 |
0.486 |
|
| 1999 |
Huang C, Ma WY, Maxiner A, Sun Y, Dong Z. p38 Kinase Mediates UV-induced Phosphorylation of p53 Protein at Serine 389 Journal of Biological Chemistry. 274: 12229-12235. PMID 10212189 DOI: 10.1074/Jbc.274.18.12229 |
0.402 |
|
| 1999 |
Huang C, Ma W, Goranson A, Dong Z. Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway. Carcinogenesis. 20: 237-242. PMID 10069459 DOI: 10.1093/Carcin/20.2.237 |
0.467 |
|
| 1998 |
Watts RG, Huang C, Young MR, Li JJ, Dong Z, Pennie WD, Colburn NH. Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation Oncogene. 17: 3493-3498. PMID 10030673 DOI: 10.1038/Sj.Onc.1202259 |
0.474 |
|
| 1998 |
Dong Z, Huang C, Ma WY, Malewicz B, Baumann WJ, Kiss Z. Increased synthesis of phosphocholine is required for UV-induced AP-1 activation. Oncogene. 17: 1845-53. PMID 9778051 DOI: 10.1038/Sj.Onc.1202084 |
0.425 |
|
| 1998 |
Huang C, Chen N, Ma W, Dong Z. Vanadium induces AP-1- and NFkappB-dependent transcription activity. International Journal of Oncology. 13: 711-715. PMID 9735400 DOI: 10.3892/Ijo.13.4.711 |
0.408 |
|
| 1998 |
Huang C, Ma W, Dong Z. Potentiation of Insulin-Induced Phosphatidylinositol-3 Kinase Activity by Phorbol Ester Is Mediated by Protein Kinase Cϵ Cellular Signalling. 10: 185-190. PMID 9607141 DOI: 10.1016/S0898-6568(97)00098-3 |
0.352 |
|
| 1998 |
Huang C, Ma WY, Yound MR, Colburn N, Dong Z. Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells Proceedings of the National Academy of Sciences of the United States of America. 95: 156-161. PMID 9419345 DOI: 10.1073/Pnas.95.1.156 |
0.463 |
|
| 1997 |
Huang C, Ma Wy, Ding M, Bowden GT, Dong Z. Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase. The Journal of Biological Chemistry. 272: 27753-7. PMID 9346918 DOI: 10.1074/Jbc.272.44.27753 |
0.409 |
|
| 1997 |
Huang C, Ma W, Ryan CA, Dong Z. Proteinase inhibitors I and II from potatoes specifically block UV-induced activator protein-1 activation through a pathway that is independent of extracellular signal-regulated kinases, c-Jun N-terminal kinases, and P38 kinase Proceedings of the National Academy of Sciences of the United States of America. 94: 11957-11962. PMID 9342344 DOI: 10.1073/Pnas.94.22.11957 |
0.456 |
|
| 1997 |
Huang C, Ma WY, Hanenberger D, Cleary MP, Bowden GT, Dong Z. Inhibition of ultraviolet B-induced activator protein-1 (AP-1) activity by aspirin in AP-1-luciferase transgenic mice. The Journal of Biological Chemistry. 272: 26325-31. PMID 9334204 DOI: 10.1074/Jbc.272.42.26325 |
0.439 |
|
| 1997 |
Huang C, Ma WY, Dawson MI, Rincon M, Flavell RA, Dong Z. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proceedings of the National Academy of Sciences of the United States of America. 94: 5826-30. PMID 9159159 DOI: 10.1073/Pnas.94.11.5826 |
0.36 |
|
| 1997 |
Huang C, Ma W, Dong Z. Signal transduction through atypical PKCs, but not the EGF receptor, is necessary for UVC-induced AP-1 activation in immortal murine cells. Oncogene. 14: 1945-1954. PMID 9150361 DOI: 10.1038/Sj.Onc.1201056 |
0.353 |
|
| 1997 |
Dong Z, Huang C, Brown RE, Ma WY. Inhibition of Activator Protein 1 Activity and Neoplastic Transformation by Aspirin Journal of Biological Chemistry. 272: 9962-9970. PMID 9092536 DOI: 10.1074/Jbc.272.15.9962 |
0.436 |
|
| 1997 |
Huang C, Schmid PC, Ma W, Schmid HHO, Dong Z. Phosphatidylinositol-3 Kinase Is Necessary for 12-O-Tetradecanoylphorbol-13-acetate-induced Cell Transformation and Activated Protein 1 Activation Journal of Biological Chemistry. 272: 4187-4194. PMID 9020132 DOI: 10.1074/Jbc.272.7.4187 |
0.404 |
|
| 1997 |
Huang C, Ma Wy, Bowden GT, Dong Z. Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKClambda/iota. The Journal of Biological Chemistry. 271: 31262-8. PMID 8940130 DOI: 10.1074/Jbc.271.49.31262 |
0.394 |
|
| 1996 |
Huang C, Ma W, Dong Z. Inhibitory effects of ascorbic acid on AP-1 activity and transformation of JB6 cells. International Journal of Oncology. 8: 389-393. PMID 21544374 DOI: 10.3892/Ijo.8.2.389 |
0.405 |
|
| 1996 |
Huang C, Ma WY, Dong Z. Requirement for phosphatidylinositol 3-kinase in epidermal growth factor-induced AP-1 transactivation and transformation in JB6 P+ cells. Molecular and Cellular Biology. 16: 6427-6435. PMID 8887671 DOI: 10.1128/Mcb.16.11.6427 |
0.423 |
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