Year |
Citation |
Score |
2019 |
Padayatti PS, Lee SC, Stanfield RL, Wen PC, Tajkhorshid E, Wilson IA, Zhang Q. Structural Insights into the Lipid A Transport Pathway in MsbA. Structure (London, England : 1993). PMID 31130486 DOI: 10.1016/J.Str.2019.04.007 |
0.32 |
|
2017 |
Ishchenko A, Peng L, Zinovev E, Vlasov A, Lee SC, Kuklin A, Mishin A, Borshchevskiy V, Zhang Q, Cherezov V. Chemically Stable Lipids for Membrane Protein Crystallization. Crystal Growth & Design. 17: 3502-3511. PMID 29290736 DOI: 10.1021/Acs.Cgd.7B00458 |
0.304 |
|
2016 |
Shah MB, Jang HH, Wilderman PR, Lee D, Li S, Zhang Q, Stout CD, Halpert JR. Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophysical Chemistry. 216: 1-8. PMID 27280734 DOI: 10.1016/J.Bpc.2016.05.007 |
0.309 |
|
2016 |
Shah MB, Liu J, Huo L, Zhang Q, Dearing MD, Wilderman PR, Szklarz GD, Stout CD, Halpert JR. Structure-Function Analysis of Mammalian CYP2B Enzymes using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Molecular Pharmacology. PMID 26826176 DOI: 10.1124/Mol.115.102111 |
0.301 |
|
2015 |
Moeller A, Lee SC, Tao H, Speir JA, Chang G, Urbatsch IL, Potter CS, Carragher B, Zhang Q. Distinct conformational spectrum of homologous multidrug ABC transporters. Structure (London, England : 1993). 23: 450-60. PMID 25661651 DOI: 10.1016/J.Str.2014.12.013 |
0.31 |
|
2015 |
Shah MB, Wilderman PR, Liu J, Jang HH, Zhang Q, Stout CD, Halpert JR. Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison. Molecular Pharmacology. 87: 649-59. PMID 25585967 DOI: 10.1124/Mol.114.097014 |
0.308 |
|
2014 |
Hildebrandt E, Zhang Q, Cant N, Ding H, Dai Q, Peng L, Fu Y, DeLucas LJ, Ford R, Kappes JC, Urbatsch IL. A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR). Biochimica Et Biophysica Acta. 1838: 2825-37. PMID 25065669 DOI: 10.1016/J.Bbamem.2014.07.016 |
0.305 |
|
2013 |
Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E1203-11. PMID 23479627 DOI: 10.1073/Pnas.1221442110 |
0.322 |
|
2013 |
Zhang H, Gay SC, Shah M, Foroozesh M, Liu J, Osawa Y, Zhang Q, Stout CD, Halpert JR, Hollenberg PF. Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: Implications for allosteric modulation of cytochrome P450 catalysis Biochemistry. 52: 355-364. PMID 23276288 DOI: 10.1021/Bi301567Z |
0.311 |
|
2012 |
Tao H, Fu Y, Thompson A, Lee SC, Mahoney N, Stevens RC, Zhang Q. Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 11173-81. PMID 22780816 DOI: 10.1021/La3020404 |
0.321 |
|
2012 |
Wilderman PR, Gay SC, Jang HH, Zhang Q, Stout CD, Halpert JR. Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme. The Febs Journal. 279: 1607-20. PMID 22051155 DOI: 10.1111/J.1742-4658.2011.08411.X |
0.301 |
|
2010 |
Gay SC, Roberts AG, Maekawa K, Talakad JC, Hong WX, Zhang Q, Stout CD, Halpert JR. Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . Biochemistry. 49: 8709-20. PMID 20815363 DOI: 10.1021/Bi100914Z |
0.308 |
|
2010 |
Annalora AJ, Goodin DB, Hong WX, Zhang Q, Johnson EF, Stout CD. Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. Journal of Molecular Biology. 396: 441-51. PMID 19961857 DOI: 10.1016/J.Jmb.2009.11.057 |
0.305 |
|
2010 |
Zhang Q, Lu X, Han X. ChemInform Abstract: Palladium(II)-Catalyzed Asymmetric Cyclization of (Z)-4′-Acetoxy-2′-butenyl 2-Alkynoates. Role of Nitrogen-Containing Ligands in Palladium(II)-Mediated Reactions. Cheminform. 33: no-no. DOI: 10.1002/chin.200218104 |
0.455 |
|
2010 |
Zhang Z, Lu X, Xu Z, Zhang Q, Han X. ChemInform Abstract: Role of Halide Ions in Divalent Palladium-Mediated Reactions: Competition Between β-Heteroatom Elimination and β-Hydride Elimination of a Carbon-Palladium Bond. Cheminform. 32: no-no. DOI: 10.1002/chin.200150031 |
0.445 |
|
2007 |
Stewart CR, Wilson LM, Zhang Q, Pham CL, Waddington LJ, Staples MK, Stapleton D, Kelly JW, Howlett GJ. Oxidized cholesterol metabolites found in human atherosclerotic lesions promote apolipoprotein C-II amyloid fibril formation. Biochemistry. 46: 5552-61. PMID 17429947 DOI: 10.1021/Bi602554Z |
0.561 |
|
2006 |
Bieschke J, Zhang Q, Bosco DA, Lerner RA, Powers ET, Wentworth P, Kelly JW. Small molecule oxidation products trigger disease-associated protein misfolding. Accounts of Chemical Research. 39: 611-9. PMID 16981677 DOI: 10.1021/Ar0500766 |
0.733 |
|
2006 |
Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nature Chemical Biology. 2: 249-53. PMID 16565714 DOI: 10.1038/Nchembio782 |
0.726 |
|
2006 |
Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. Correction: Corrigendum: Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate α-synuclein fibrilization Nature Chemical Biology. 2: 346-346. DOI: 10.1038/Nchembio0606-346B |
0.719 |
|
2005 |
Zhang Q, Kelly JW. Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice? Biochemistry. 44: 9079-85. PMID 15966731 DOI: 10.1021/Bi050378F |
0.53 |
|
2005 |
Bieschke J, Zhang Q, Powers ET, Lerner RA, Kelly JW. Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation. Biochemistry. 44: 4977-83. PMID 15794636 DOI: 10.1021/Bi0501030 |
0.747 |
|
2005 |
Zhang Q, Xu W, Lu X. Cycloisomerization of 1,6-enynes using acetate as a nucleophile under palladium(II) catalysis. The Journal of Organic Chemistry. 70: 1505-7. PMID 15704997 DOI: 10.1021/Jo048414O |
0.51 |
|
2004 |
Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P, Lerner RA, Kelly JW. Metabolite-initiated protein misfolding may trigger Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 4752-7. PMID 15034169 DOI: 10.1073/Pnas.0400924101 |
0.714 |
|
2003 |
Zhang Q, Kelly JW. Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions. Biochemistry. 42: 8756-61. PMID 12873136 DOI: 10.1021/Bi030077A |
0.482 |
|
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