Year |
Citation |
Score |
2023 |
Barasa L, Thompson PR. Protein citrullination: inhibition, identification and insertion. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220240. PMID 37778377 DOI: 10.1098/rstb.2022.0240 |
0.336 |
|
2021 |
Mondal S, Thompson PR. Chemical biology of protein citrullination by the protein A arginine deiminases. Current Opinion in Chemical Biology. 63: 19-27. PMID 33676233 DOI: 10.1016/j.cbpa.2021.01.010 |
0.348 |
|
2020 |
Loring HS, Parelkar SS, Mondal S, Thompson PR. Identification of the first noncompetitive SARM1 inhibitors. Bioorganic & Medicinal Chemistry. 28: 115644. PMID 32828421 DOI: 10.1016/J.Bmc.2020.115644 |
0.385 |
|
2020 |
Humphries F, Shmuel-Galia L, Ketelut-Carneiro N, Li S, Wang B, Nemmara VV, Wilson R, Jiang Z, Khalighinejad F, Muneeruddin K, Shaffer SA, Dutta R, Ionete C, Pesiridis S, Yang S, ... Thompson PR, et al. Succination inactivates gasdermin D and blocks pyroptosis. Science (New York, N.Y.). PMID 32820063 DOI: 10.1126/Science.Abb9818 |
0.333 |
|
2020 |
Li G, Young CH, Snow B, Christensen AO, Demoruelle MK, Nemmara VV, Thompson PR, Rothfuss HM, Cherrington BD. Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. International Journal of Molecular Sciences. 21. PMID 32290104 DOI: 10.3390/Ijms21072634 |
0.383 |
|
2020 |
Wu Z, Deng Q, Pan B, Alam HB, Tian Y, Bhatti UF, Liu B, Mondal S, Thompson PR, Li Y. Inhibition of PAD2 Improves Survival in a Mouse Model of Lethal LPS-Induced Endotoxic Shock. Inflammation. PMID 32239392 DOI: 10.1007/S10753-020-01221-0 |
0.329 |
|
2020 |
Uysal-Onganer P, MacLatchy A, Mahmoud R, Kraev I, Thompson PR, Inal JM, Lange S. Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines. International Journal of Molecular Sciences. 21. PMID 32098295 DOI: 10.3390/Ijms21041495 |
0.323 |
|
2020 |
Loring HS, Icso JD, Nemmara V, Thompson PR. Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1. Biochemistry. PMID 32049506 DOI: 10.1021/Acs.Biochem.9B01078 |
0.341 |
|
2020 |
Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson PR, Buckner JH, Robinson WH, Fox DA, et al. Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan. Science Immunology. 5. PMID 32005681 DOI: 10.1126/sciimmunol.aaz9319 |
0.688 |
|
2019 |
Loring HS, Thompson PR. Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases. Cell Chemical Biology. PMID 31761689 DOI: 10.1016/J.Chembiol.2019.11.002 |
0.343 |
|
2019 |
Sun B, Chang HH, Salinger A, Tomita B, Bawadekar M, Holmes CL, Shelef MA, Weerapana E, Thompson PR, Ho IC. Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination. Jci Insight. 4. PMID 31723060 DOI: 10.1172/Jci.Insight.129687 |
0.324 |
|
2019 |
Mishra N, Schwerdtner L, Sams K, Mondal S, Ahmad F, Schmidt RE, Coonrod SA, Thompson PR, Lerch MM, Bossaller L. Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 31292215 DOI: 10.4049/Jimmunol.1800720 |
0.365 |
|
2019 |
Mondal S, Gong X, Zhang X, Salinger AJ, Zheng L, Sen S, Weerapana E, Zhang X, Thompson P. Halogen Bonding Increases the Potency and Isozyme-selectivity of Protein Arginine Deiminase 1 Inhibitors. Angewandte Chemie (International Ed. in English). PMID 31276611 DOI: 10.1002/Anie.201906334 |
0.436 |
|
2019 |
Sorvillo N, Mizurini D, Coxon C, Martinod K, Tilvawala R, Cherpokova D, Salinger AJ, Seward RJ, Staudinger C, Weerapana E, Shapiro NI, Costello CE, Thompson P, Wagner DD. Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis after Vessel Injury. Circulation Research. PMID 31248335 DOI: 10.1161/Circresaha.118.314571 |
0.329 |
|
2019 |
Zheng L, Nagar M, Maurais AJ, Slade DJ, Parelkar SS, Coonrod SA, Weerapana E, Thompson PR. Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2. Biochemistry. PMID 31243954 DOI: 10.1021/Acs.Biochem.9B00225 |
0.696 |
|
2019 |
Sen S, Mondal S, Zheng L, Salinger AJ, Fast W, Weerapana E, Thompson PR. Development of a Suicide Inhibition Based Protein Labeling (SIBLing) Strategy for Nicotinamide N-methyltransferase. Acs Chemical Biology. PMID 30933557 DOI: 10.1021/Acschembio.9B00211 |
0.406 |
|
2019 |
Cau L, Takahara H, Thompson PR, Serre G, Méchin MC, Simon M. Peptidylarginine Deiminase Inhibitor Cl-amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis. The Journal of Investigative Dermatology. PMID 30878672 DOI: 10.1016/J.Jid.2019.02.026 |
0.383 |
|
2019 |
Nagar M, Tilvawala R, Thompson PR. Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination. Frontiers in Immunology. 10: 244. PMID 30853960 DOI: 10.3389/Fimmu.2019.00244 |
0.407 |
|
2019 |
Mondal S, Thompson PR. Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination. Accounts of Chemical Research. PMID 30844238 DOI: 10.1021/Acs.Accounts.9B00024 |
0.488 |
|
2019 |
Tilvawala R, Thompson PR. Peptidyl arginine deiminases: detection and functional analysis of protein citrullination. Current Opinion in Structural Biology. PMID 30833201 DOI: 10.1016/J.Sbi.2019.01.024 |
0.387 |
|
2018 |
Liu Y, Lightfoot YL, Seto N, Carmona-Rivera C, Moore E, Goel R, O'Neil L, Mistry P, Hoffmann V, Mondal S, Premnath PN, Gribbons K, Dell'Orso S, Jiang K, Thompson PR, et al. Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. Jci Insight. 3. PMID 30518690 DOI: 10.1172/Jci.Insight.124729 |
0.344 |
|
2018 |
Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ. Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix. Nature Communications. 9: 4783. PMID 30429478 DOI: 10.1038/S41467-018-07306-7 |
0.662 |
|
2018 |
Nemmara VV, Thompson PR. Development of Activity-Based Proteomic Probes for Protein Citrullination. Current Topics in Microbiology and Immunology. PMID 30203394 DOI: 10.1007/82_2018_132 |
0.467 |
|
2018 |
Loring HS, Thompson PR. Kinetic Mechanism of Nicotinamide N-Methyltransferase. Biochemistry. PMID 30148963 DOI: 10.1021/Acs.Biochem.8B00775 |
0.393 |
|
2018 |
Nemmara VV, Tilvawala R, Salinger AJ, Miller L, Nguyen SH, Weerapana E, Thompson PR. Citrullination Inactivates Nicotinamide-N-methyltransferase. Acs Chemical Biology. PMID 30044909 DOI: 10.1021/Acschembio.8B00578 |
0.365 |
|
2018 |
DeVore SB, Young CH, Li G, Sundararajan A, Ramaraj T, Mudge J, Schilkey F, Muth A, Thompson PR, Cherrington BD. Histone citrullination represses miRNA expression resulting in increased oncogene mRNAs in somatolactotrope cells. Molecular and Cellular Biology. PMID 29987187 DOI: 10.1128/Mcb.00084-18 |
0.681 |
|
2018 |
Ledet MM, Anderson R, Harman R, Muth A, Thompson PR, Coonrod SA, Van de Walle GR. BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway. Bmc Cancer. 18: 412. PMID 29649984 DOI: 10.1186/S12885-018-4323-8 |
0.677 |
|
2018 |
Tilvawala R, Nguyen SH, Maurais AJ, Nemmara VV, Nagar M, Salinger AJ, Nagpal S, Weerapana E, Thompson PR. The Rheumatoid Arthritis-Associated Citrullinome. Cell Chemical Biology. PMID 29628436 DOI: 10.1016/J.Chembiol.2018.03.002 |
0.411 |
|
2018 |
Carmona-Rivera C, Bicker KL, Thompson PR, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis". Science Immunology. 3. PMID 29602804 DOI: 10.1126/sciimmunol.aar3701 |
0.705 |
|
2018 |
Mondal S, Parelkar SS, Nagar M, Thompson PR. Photochemical Control of Protein Arginine Deiminase (PAD) Activity. Acs Chemical Biology. PMID 29517899 DOI: 10.1021/Acschembio.8B00053 |
0.409 |
|
2018 |
Wong A, Bryzek D, Dobosz E, Scavenius C, Svoboda P, Rapala-Kozik M, Lesner A, Frydrych I, Enghild J, Mydel P, Pohl J, Thompson PR, Potempa J, Koziel J. A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA. Journal of Immunology (Baltimore, Md. : 1950). PMID 29475987 DOI: 10.4049/Jimmunol.1701391 |
0.318 |
|
2018 |
Nemmara VJ, Subramanian V, Muth A, Mondal S, Salinger AJ, Maurais AJ, Tilvawala R, Weerapana E, Thompson PR. The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs). Acs Chemical Biology. PMID 29341591 DOI: 10.1021/Acschembio.7B00957 |
0.731 |
|
2017 |
Young CH, Rothfuss HM, Gard PF, Muth A, Thompson PR, Ashley RL, Cherrington BD. Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells. Reproduction (Cambridge, England). 153: 1-10. PMID 29565015 DOI: 10.1530/Rep-16-0494 |
0.702 |
|
2017 |
Qin H, Liu X, Li F, Miao L, Li T, Xu B, An X, Muth A, Thompson PR, Coonrod SA, Zhang X. PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling. Cancer Letters. PMID 28844713 DOI: 10.1016/J.Canlet.2017.08.019 |
0.683 |
|
2017 |
Sun B, Dwivedi N, Bechtel TJ, Paulsen JL, Muth A, Bawadekar M, Li G, Thompson PR, Shelef MA, Schiffer CA, Weerapana E, Ho IC. Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα. Science Immunology. 2. PMID 28783661 DOI: 10.1126/Sciimmunol.Aal3062 |
0.669 |
|
2017 |
Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, et al. Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis. Science Immunology. 2. PMID 28649674 DOI: 10.1126/Sciimmunol.Aag3358 |
0.734 |
|
2017 |
Kenny EF, Herzig A, Krüger R, Muth A, Mondal S, Thompson PR, Brinkmann V, Von Bernuth H, Zychlinsky A. Diverse stimuli engage different neutrophil extracellular trap pathways. Elife. 6. PMID 28574339 DOI: 10.7554/Elife.24437 |
0.687 |
|
2017 |
Kosgodage US, Trindade RP, Thompson PR, Inal JM, Lange S. Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy. International Journal of Molecular Sciences. 18. PMID 28486412 DOI: 10.3390/Ijms18051007 |
0.316 |
|
2017 |
Clancy KW, Russell AM, Subramanian V, Nguyen H, Qian Y, Campbell RM, Thompson PR. Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription. Acs Chemical Biology. PMID 28485572 DOI: 10.1021/Acschembio.7B00241 |
0.377 |
|
2017 |
Muth A, Subramanian V, Beaumont E, Nagar M, Kerry P, McEwan P, Srinath H, Clancy KW, Parelkar SS, Thompson PR. Development of a selective inhibitor of Protein Arginine Deiminase 2. Journal of Medicinal Chemistry. PMID 28328217 DOI: 10.1021/Acs.Jmedchem.7B00274 |
0.699 |
|
2017 |
Foyn H, Thompson PR, Arnesen T. DTNB-Based Quantification of In Vitro Enzymatic N-Terminal Acetyltransferase Activity. Methods in Molecular Biology (Clifton, N.J.). 1574: 9-15. PMID 28315240 DOI: 10.1007/978-1-4939-6850-3_2 |
0.335 |
|
2017 |
Cau L, Pendaries V, Lhuillier E, Thompson PR, Serre G, Takahara H, Méchin MC, Simon M. Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown. Journal of Dermatological Science. PMID 28242341 DOI: 10.1016/J.Jdermsci.2017.02.280 |
0.39 |
|
2017 |
Kenny EF, Herzig A, Krüger R, Muth A, Mondal S, Thompson PR, Brinkmann V, Bernuth Hv, Zychlinsky A. Author response: Diverse stimuli engage different neutrophil extracellular trap pathways Elife. DOI: 10.7554/Elife.24437.032 |
0.631 |
|
2016 |
Zhang X, Liu X, Zhang M, Li T, Muth A, Thompson PR, Coonrod SA, Zhang X. Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development. Scientific Reports. 6: 38727. PMID 27929094 DOI: 10.1038/Srep38727 |
0.707 |
|
2016 |
Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, et al. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. Jci Insight. 1: e90045. PMID 27777982 DOI: 10.1172/Jci.Insight.90045 |
0.317 |
|
2016 |
Khan SA, Edwards BS, Muth A, Thompson PR, Cherrington BD, Navratil AM. GnRH stimulates peptidylarginine deiminase catalyzed histone citrullination in gonadotrope cells. Molecular Endocrinology (Baltimore, Md.). me20161085. PMID 27603413 DOI: 10.1210/Me.2016-1085 |
0.702 |
|
2016 |
Papadaki G, Kambas K, Choulaki C, Vlachou K, Drakos E, Bertsias G, Ritis K, Boumpas DT, Thompson PR, Verginis P, Sidiropoulos P. Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation. European Journal of Immunology. PMID 27585946 DOI: 10.1002/Eji.201646542 |
0.334 |
|
2016 |
Fuhrmann J, Subramanian V, Kojetin DJ, Thompson PR. Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation. Cell Chemical Biology. PMID 27524296 DOI: 10.1016/J.Chembiol.2016.07.008 |
0.742 |
|
2016 |
Kawalkowska J, Quirke AM, Ghari F, Davis S, Subramanian V, Thompson PR, Williams RO, Fischer R, La Thangue NB, Venables PJ. Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses. Scientific Reports. 6: 26430. PMID 27210478 DOI: 10.1038/Srep26430 |
0.368 |
|
2016 |
Ghari F, Quirke AM, Munro S, Kawalkowska J, Picaud S, McGouran J, Subramanian V, Muth A, Williams R, Kessler B, Thompson PR, Fillipakopoulos P, Knapp S, Venables PJ, La Thangue NB. Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response. Science Advances. 2: e1501257. PMID 26989780 DOI: 10.1126/Sciadv.1501257 |
0.714 |
|
2016 |
Li G, Hayward IN, Jenkins BR, Rothfuss HM, Young CH, Nevalainen MT, Muth A, Thompson PR, Navratil AM, Cherrington BD. Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland. Plos One. 11: e0147503. PMID 26799659 DOI: 10.1371/Journal.Pone.0147503 |
0.696 |
|
2016 |
Grayson P, Carmona-Rivera C, Graf J, Irizarry-Caro J, Phillips K, Preston K, Purmalek M, Subramaniam V, Thompson P, Waldman M, Kaplan M. OP0054 Neuroimmunomodulation of Neutrophils as A Novel Mechanism of Levamisole-Induced Vasculitis Annals of the Rheumatic Diseases. 75: 74.3-75. DOI: 10.1136/Annrheumdis-2016-Eular.2963 |
0.336 |
|
2016 |
Kawalkowska J, Quirke A, Ghari F, Subramanian V, Li R, Thompson P, Williams R, Fischer R, Thangue NL, Venables P. A7.01 Abrogation of collagen-induced arthritis by a second generation peptidyl arginine deiminase inhibitor is associated with a shift from TH1/TH17 to TH2-mediated immune responses Annals of the Rheumatic Diseases. 75: A56.1-A56. DOI: 10.1136/Annrheumdis-2016-209124.132 |
0.343 |
|
2015 |
Fuhrmann J, Thompson PR. Protein Arginine Methylation and Citrullination in Epigenetic Regulation. Acs Chemical Biology. PMID 26686581 DOI: 10.1021/Acschembio.5B00942 |
0.764 |
|
2015 |
Clancy KW, Weerapana E, Thompson PR. Detection and identification of protein citrullination in complex biological systems. Current Opinion in Chemical Biology. 30: 1-6. PMID 26517730 DOI: 10.1016/J.Cbpa.2015.10.014 |
0.431 |
|
2015 |
Fuhrmann J, Subramanian V, Thompson PR. Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angewandte Chemie (International Ed. in English). PMID 26458230 DOI: 10.1002/Anie.201506737 |
0.731 |
|
2015 |
Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer. Oncotarget. PMID 26440311 DOI: 10.18632/Oncotarget.5937 |
0.708 |
|
2015 |
Lewallen DM, Bicker KL, Subramanian V, Clancy KW, Slade DJ, Martell J, Dreyton CJ, Sokolove J, Weerapana E, Thompson PR. Chemical Proteomic Platform To Identify Citrullinated Proteins. Acs Chemical Biology. PMID 26360112 DOI: 10.1021/Acschembio.5B00438 |
0.8 |
|
2015 |
Kholia S, Jorfi S, Thompson PR, Causey CP, Nicholas AP, Inal JM, Lange S. A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy. Journal of Extracellular Vesicles. 4: 26192. PMID 26095379 DOI: 10.3402/Jev.V4.26192 |
0.719 |
|
2015 |
Horibata S, Vo TV, Subramanian V, Thompson PR, Coonrod SA. Utilization of the Soft Agar Colony Formation Assay to Identify Inhibitors of Tumorigenicity in Breast Cancer Cells. Journal of Visualized Experiments : Jove. PMID 26067809 DOI: 10.3791/52727 |
0.332 |
|
2015 |
Fuhrmann J, Clancy KW, Thompson PR. Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation. Chemical Reviews. 115: 5413-61. PMID 25970731 DOI: 10.1021/Acs.Chemrev.5B00003 |
0.746 |
|
2015 |
Witalison EE, Thompson PR, Hofseth LJ. Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation. Current Drug Targets. PMID 25642720 DOI: 10.2174/1389450116666150202160954 |
0.457 |
|
2015 |
Witalison EE, Cui X, Hofseth AB, Subramanian V, Causey CP, Thompson PR, Hofseth LJ. Inhibiting protein arginine deiminases has antioxidant consequences. The Journal of Pharmacology and Experimental Therapeutics. 353: 64-70. PMID 25635139 DOI: 10.1124/Jpet.115.222745 |
0.71 |
|
2015 |
Lewis HD, Liddle J, Coote JE, Atkinson SJ, Barker MD, Bax BD, Bicker KL, Bingham RP, Campbell M, Chen YH, Chung CW, Craggs PD, Davis RP, Eberhard D, Joberty G, ... ... Thompson PR, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nature Chemical Biology. 11: 189-91. PMID 25622091 DOI: 10.1038/Nchembio.1735 |
0.809 |
|
2015 |
Slade DJ, Fang P, Dreyton CJ, Zhang Y, Fuhrmann J, Rempel D, Bax BD, Coonrod SA, Lewis HD, Guo M, Gross ML, Thompson PR. Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chemical Biology. 10: 1043-53. PMID 25621824 DOI: 10.1021/Cb500933J |
0.806 |
|
2015 |
Subramanian V, Knight JS, Parelkar S, Anguish L, Coonrod SA, Kaplan MJ, Thompson PR. Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors. Journal of Medicinal Chemistry. 58: 1337-44. PMID 25559347 DOI: 10.1021/Jm501636X |
0.45 |
|
2015 |
Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Abstract 238: Citrullination of miRNA regulators by PADs: A potential mechanism for the promotion of colitis and colitis-associated colorectal cancer Cancer Research. 75: 238-238. DOI: 10.1158/1538-7445.Am2015-238 |
0.688 |
|
2014 |
Wang M, Fuhrmann J, Thompson PR. Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Biochemistry. 53: 7884-92. PMID 25485739 DOI: 10.1021/Bi501279G |
0.777 |
|
2014 |
Knight JS, Subramanian V, O'Dell AA, Yalavarthi S, Zhao W, Smith CK, Hodgin JB, Thompson PR, Kaplan MJ. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Annals of the Rheumatic Diseases. PMID 25104775 DOI: 10.1136/Annrheumdis-2014-205365 |
0.3 |
|
2014 |
Dreyton CJ, Knuckley B, Jones JE, Lewallen DM, Thompson PR. Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism. Biochemistry. 53: 4426-33. PMID 24989433 DOI: 10.1021/Bi500554B |
0.812 |
|
2014 |
Slade DJ, Horibata S, Coonrod SA, Thompson PR. A novel role for protein arginine deiminase 4 in pluripotency: the emerging role of citrullinated histone H1 in cellular programming. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 736-40. PMID 24889365 DOI: 10.1002/Bies.201400057 |
0.698 |
|
2014 |
Lange S, Rocha-Ferreira E, Thei L, Mawjee P, Bennett K, Thompson PR, Subramanian V, Nicholas AP, Peebles D, Hristova M, Raivich G. Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates. Journal of Neurochemistry. 130: 555-62. PMID 24762056 DOI: 10.1111/Jnc.12744 |
0.397 |
|
2014 |
Slade DJ, Subramanian V, Thompson PR. Pluripotency: citrullination unravels stem cells. Nature Chemical Biology. 10: 327-8. PMID 24743255 DOI: 10.1038/Nchembio.1504 |
0.671 |
|
2014 |
Dwivedi N, Neeli I, Schall N, Wan H, Desiderio DM, Csernok E, Thompson PR, Dali H, Briand JP, Muller S, Radic M. Deimination of linker histones links neutrophil extracellular trap release with autoantibodies in systemic autoimmunity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2840-51. PMID 24671707 DOI: 10.1096/Fj.13-247254 |
0.336 |
|
2014 |
U KP, Subramanian V, Nicholas AP, Thompson PR, Ferretti P. Modulation of calcium-induced cell death in human neural stem cells by the novel peptidylarginine deiminase-AIF pathway. Biochimica Et Biophysica Acta. 1843: 1162-71. PMID 24607566 DOI: 10.1016/J.Bbamcr.2014.02.018 |
0.335 |
|
2014 |
Lewallen DM, Bicker KL, Madoux F, Chase P, Anguish L, Coonrod S, Hodder P, Thompson PR. A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs. Acs Chemical Biology. 9: 913-21. PMID 24467619 DOI: 10.1021/Cb400841K |
0.774 |
|
2014 |
Dreyton CJ, Anderson ED, Subramanian V, Boger DL, Thompson PR. Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation. Bioorganic & Medicinal Chemistry. 22: 1362-9. PMID 24440480 DOI: 10.1016/J.Bmc.2013.12.064 |
0.465 |
|
2014 |
Knight JS, Luo W, O'Dell AA, Yalavarthi S, Zhao W, Subramanian V, Guo C, Grenn RC, Thompson PR, Eitzman DT, Kaplan MJ. Peptidylarginine deiminase inhibition reduces vascular damage and modulates innate immune responses in murine models of atherosclerosis. Circulation Research. 114: 947-56. PMID 24425713 DOI: 10.1161/Circresaha.114.303312 |
0.307 |
|
2014 |
Rust HL, Subramanian V, West GM, Young DD, Schultz PG, Thompson PR. Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. Acs Chemical Biology. 9: 649-55. PMID 24358983 DOI: 10.1021/Cb400859Z |
0.406 |
|
2014 |
Lewallen DM, Sreelatha A, Dharmarajan V, Madoux F, Chase P, Griffin PR, Orth K, Hodder P, Thompson PR. Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation. Acs Chemical Biology. 9: 433-42. PMID 24274060 DOI: 10.1021/Cb4006886 |
0.399 |
|
2014 |
Slade DJ, Subramanian V, Fuhrmann J, Thompson PR. Chemical and biological methods to detect post-translational modifications of arginine. Biopolymers. 101: 133-43. PMID 23576281 DOI: 10.1002/Bip.22256 |
0.816 |
|
2014 |
Witalison EE, Cui X, Thompson PR, Hofseth LJ. Abstract 3782: Cl-amidine, a PAD inhibitor, prevents UC and CRC in mice: Exploring novel mechanisms of miRNA and oxidative stress regulation Cancer Research. 74: 3782-3782. DOI: 10.1158/1538-7445.Am2014-3782 |
0.379 |
|
2013 |
Dillon MB, Rust HL, Thompson PR, Mowen KA. Automethylation of protein arginine methyltransferase 8 (PRMT8) regulates activity by impeding S-adenosylmethionine sensitivity. The Journal of Biological Chemistry. 288: 27872-80. PMID 23946480 DOI: 10.1074/Jbc.M113.491092 |
0.417 |
|
2013 |
Wang M, Xu RM, Thompson PR. Substrate specificity, processivity, and kinetic mechanism of protein arginine methyltransferase 5. Biochemistry. 52: 5430-40. PMID 23866019 DOI: 10.1021/Bi4005123 |
0.452 |
|
2013 |
Fuhrmann J, Subramanian V, Thompson PR. Targeting the arginine phosphatase YwlE with a catalytic redox-based inhibitor. Acs Chemical Biology. 8: 2024-32. PMID 23838530 DOI: 10.1021/Cb4001469 |
0.771 |
|
2013 |
Knight JS, Zhao W, Luo W, Subramanian V, O'Dell AA, Yalavarthi S, Hodgin JB, Eitzman DT, Thompson PR, Kaplan MJ. Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus. The Journal of Clinical Investigation. 123: 2981-93. PMID 23722903 DOI: 10.1172/Jci67390 |
0.359 |
|
2013 |
Foyn H, Jones JE, Lewallen D, Narawane R, Varhaug JE, Thompson PR, Arnesen T. Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. Acs Chemical Biology. 8: 1121-7. PMID 23557624 DOI: 10.1021/Cb400136S |
0.756 |
|
2013 |
Khandpur R, Carmona-Rivera C, Vivekanandan-Giri A, Gizinski A, Yalavarthi S, Knight JS, Friday S, Li S, Patel RM, Subramanian V, Thompson P, Chen P, Fox DA, Pennathur S, Kaplan MJ. NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis. Science Translational Medicine. 5: 178ra40. PMID 23536012 DOI: 10.1126/Scitranslmed.3005580 |
0.311 |
|
2013 |
Cui X, Witalison EE, Chumanevich AP, Chumanevich AA, Poudyal D, Subramanian V, Schetter AJ, Harris CC, Thompson PR, Hofseth LJ. The induction of microRNA-16 in colon cancer cells by protein arginine deiminase inhibition causes a p53-dependent cell cycle arrest. Plos One. 8: e53791. PMID 23308284 DOI: 10.1371/Journal.Pone.0053791 |
0.312 |
|
2013 |
Bicker KL, Thompson PR. The protein arginine deiminases: Structure, function, inhibition, and disease. Biopolymers. 99: 155-63. PMID 23175390 DOI: 10.1002/Bip.22127 |
0.792 |
|
2012 |
Bicker KL, Sun J, Harrell M, Zhang Y, Pena MM, Thompson PR, Lavigne JJ. Synthetic lectin arrays for the detection and discrimination of cancer associated glycans and cell lines. Chemical Science. 3: 1147-1156. PMID 29051806 DOI: 10.1039/C2Sc00790H |
0.732 |
|
2012 |
Bicker KL, Anguish L, Chumanevich AA, Cameron MD, Cui X, Witalison E, Subramanian V, Zhang X, Chumanevich AP, Hofseth LJ, Coonrod SA, Thompson PR. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. Acs Medicinal Chemistry Letters. 3: 1081-1085. PMID 23420624 DOI: 10.1021/Ml300288D |
0.764 |
|
2012 |
Rohrbach AS, Slade DJ, Thompson PR, Mowen KA. Activation of PAD4 in NET formation. Frontiers in Immunology. 3: 360. PMID 23264775 DOI: 10.3389/Fimmu.2012.00360 |
0.704 |
|
2012 |
McElwee JL, Mohanan S, Griffith OL, Breuer HC, Anguish LJ, Cherrington BD, Palmer AM, Howe LR, Subramanian V, Causey CP, Thompson PR, Gray JW, Coonrod SA. Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. Bmc Cancer. 12: 500. PMID 23110523 DOI: 10.1186/1471-2407-12-500 |
0.712 |
|
2012 |
Bicker KL, Subramanian V, Chumanevich AA, Hofseth LJ, Thompson PR. Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination. Journal of the American Chemical Society. 134: 17015-8. PMID 23030787 DOI: 10.1021/Ja308871V |
0.766 |
|
2012 |
Mohanan S, Cherrington BD, Horibata S, McElwee JL, Thompson PR, Coonrod SA. Potential role of peptidylarginine deiminase enzymes and protein citrullination in cancer pathogenesis. Biochemistry Research International. 2012: 895343. PMID 23019525 DOI: 10.1155/2012/895343 |
0.405 |
|
2012 |
Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation. Proceedings of the National Academy of Sciences of the United States of America. 109: 13331-6. PMID 22853951 DOI: 10.1073/Pnas.1203280109 |
0.782 |
|
2012 |
Kan R, Jin M, Subramanian V, Causey CP, Thompson PR, Coonrod SA. Potential role for PADI-mediated histone citrullination in preimplantation development. Bmc Developmental Biology. 12: 19. PMID 22712504 DOI: 10.1186/1471-213X-12-19 |
0.728 |
|
2012 |
Mohamed BM, Verma NK, Davies AM, McGowan A, Crosbie-Staunton K, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y. Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo. Nanomedicine (London, England). 7: 1181-95. PMID 22625207 DOI: 10.2217/Nnm.11.177 |
0.712 |
|
2012 |
Lewallen DM, Steckler CJ, Knuckley B, Chalmers MJ, Thompson PR. Probing adenylation: Using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates Molecular Biosystems. 8: 1701-1706. PMID 22456874 DOI: 10.1039/C2Mb25053E |
0.735 |
|
2012 |
Evjenth RH, Brenner AK, Thompson PR, Arnesen T, Frøystein NÅ, Lillehaug JR. Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study. The Journal of Biological Chemistry. 287: 10081-8. PMID 22311970 DOI: 10.1074/Jbc.M111.326587 |
0.374 |
|
2012 |
Obianyo O, Thompson PR. Kinetic mechanism of protein arginine methyltransferase 6 (PRMT6). The Journal of Biological Chemistry. 287: 6062-71. PMID 22219200 DOI: 10.1074/Jbc.M111.333609 |
0.463 |
|
2012 |
Dwivedi N, Upadhyay J, Neeli I, Khan S, Pattanaik D, Myers L, Kirou KA, Hellmich B, Knuckley B, Thompson PR, Crow MK, Mikuls TR, Csernok E, Radic M. Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps. Arthritis and Rheumatism. 64: 982-992. PMID 22034172 DOI: 10.1002/Art.33432 |
0.711 |
|
2012 |
Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. Acs Chemical Biology. 7: 160-5. PMID 22004374 DOI: 10.1021/Cb200258Q |
0.817 |
|
2012 |
Obianyo O, Thompson PR. Reply to Frankel: Inconvenient Truths for PRMT6 Kinetic Studies Journal of Biological Chemistry. 287: 9513-9513. DOI: 10.1074/Jbc.N111.333609 |
0.353 |
|
2012 |
Bicker KL, Sun J, Harrell M, Zhang Y, Pena MM, Thompson PR, Lavigne JJ. Synthetic lectin arrays for the detection and discrimination of cancer associated glycans and cell lines Chemical Science. 3: 1147-1156. DOI: 10.1039/c2sc00790h |
0.716 |
|
2011 |
Causey CP, Jones JE, Slack JL, Kamei D, Jones LE, Subramanian V, Knuckley B, Ebrahimi P, Chumanevich AA, Luo Y, Hashimoto H, Sato M, Hofseth LJ, Thompson PR. The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. Journal of Medicinal Chemistry. 54: 6919-35. PMID 21882827 DOI: 10.1021/Jm2008985 |
0.782 |
|
2011 |
Obianyo O, Causey CP, Jones JE, Thompson PR. Activity-based protein profiling of protein arginine methyltransferase 1. Acs Chemical Biology. 6: 1127-35. PMID 21838253 DOI: 10.1021/Cb2001473 |
0.815 |
|
2011 |
Rust HL, Thompson PR. Kinase consensus sequences: a breeding ground for crosstalk. Acs Chemical Biology. 6: 881-92. PMID 21721511 DOI: 10.1021/Cb200171D |
0.357 |
|
2011 |
Zhang X, Gamble MJ, Stadler S, Cherrington BD, Causey CP, Thompson PR, Roberson MS, Kraus WL, Coonrod SA. Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. Plos Genetics. 7: e1002112. PMID 21655091 DOI: 10.1371/Journal.Pgen.1002112 |
0.721 |
|
2011 |
Lange S, Gögel S, Leung KY, Vernay B, Nicholas AP, Causey CP, Thompson PR, Greene ND, Ferretti P. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Developmental Biology. 355: 205-14. PMID 21539830 DOI: 10.1016/J.Ydbio.2011.04.015 |
0.693 |
|
2011 |
Slack JL, Jones LE, Bhatia MM, Thompson PR. Autodeimination of protein arginine deiminase 4 alters protein-protein interactions but not activity Biochemistry. 50: 3997-4010. PMID 21466234 DOI: 10.1021/Bi200309E |
0.483 |
|
2011 |
Rust HL, Zurita-Lopez CI, Clarke S, Thompson PR. Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1. Biochemistry. 50: 3332-45. PMID 21417440 DOI: 10.1021/Bi102022E |
0.394 |
|
2011 |
Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ. Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G929-38. PMID 21415415 DOI: 10.1152/Ajpgi.00435.2010 |
0.787 |
|
2011 |
Bicker KL, Sun J, Lavigne JJ, Thompson PR. Boronic acid functionalized peptidyl synthetic lectins: combinatorial library design, peptide sequencing, and selective glycoprotein recognition. Acs Combinatorial Science. 13: 232-43. PMID 21405093 DOI: 10.1021/Co100054E |
0.73 |
|
2011 |
Willis VC, Gizinski AM, Banda NK, Causey CP, Knuckley B, Cordova KN, Luo Y, Levitt B, Glogowska M, Chandra P, Kulik L, Robinson WH, Arend WP, Thompson PR, Holers VM. N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. Journal of Immunology (Baltimore, Md. : 1950). 186: 4396-404. PMID 21346230 DOI: 10.4049/Jimmunol.1001620 |
0.803 |
|
2011 |
Slack JL, Causey CP, Luo Y, Thompson PR. Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4. Acs Chemical Biology. 6: 466-76. PMID 21265574 DOI: 10.1021/Cb1003515 |
0.769 |
|
2011 |
Slack JL, Causey CP, Thompson PR. Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cellular and Molecular Life Sciences : Cmls. 68: 709-20. PMID 20706768 DOI: 10.1007/S00018-010-0480-X |
0.741 |
|
2011 |
Bicker KL, Obianyo O, Rust HL, Thompson PR. A combinatorial approach to characterize the substrate specificity of protein arginine methyltransferase 1. Molecular Biosystems. 7: 48-51. PMID 20607165 DOI: 10.1039/C0Mb00015A |
0.763 |
|
2011 |
Taki H, Gomi T, Knuckley B, Thompson PR, Vugrek O, Hirata K, Miyahara T, Shinoda K, Hounoki H, Sugiyama E, Usui I, Urakaze M, Tobe K, Ishimoto T, Inoue R, et al. Purification of enzymatically inactive peptidylarginine deiminase type 6 from mouse ovary that reveals hexameric structure different from other dimeric isoforms Advances in Bioscience and Biotechnology. 2: 304-310. DOI: 10.4236/Abb.2011.24044 |
0.751 |
|
2010 |
Jones JE, Dreyton CJ, Flick H, Causey CP, Thompson PR. Mechanistic studies of agmatine deiminase from multiple bacterial species. Biochemistry. 49: 9413-23. PMID 20939536 DOI: 10.1021/Bi101405Y |
0.794 |
|
2010 |
Knuckley B, Jones JE, Bachovchin DA, Slack J, Causey CP, Brown SJ, Rosen H, Cravatt BF, Thompson PR. A fluopol-ABPP HTS assay to identify PAD inhibitors. Chemical Communications (Cambridge, England). 46: 7175-7. PMID 20740228 DOI: 10.1039/C0Cc02634D |
0.796 |
|
2010 |
Obianyo O, Causey CP, Osborne TC, Jones JE, Lee YH, Stallcup MR, Thompson PR. A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation. Chembiochem : a European Journal of Chemical Biology. 11: 1219-23. PMID 20480486 DOI: 10.1002/Cbic.201000209 |
0.825 |
|
2010 |
Knuckley B, Causey CP, Jones JE, Bhatia M, Dreyton CJ, Osborne TC, Takahara H, Thompson PR. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry. 49: 4852-63. PMID 20469888 DOI: 10.1021/Bi100363T |
0.822 |
|
2010 |
Jones JE, Causey CP, Lovelace L, Knuckley B, Flick H, Lebioda L, Thompson PR. Characterization and inactivation of an agmatine deiminase from Helicobacter pylori. Bioorganic Chemistry. 38: 62-73. PMID 20036411 DOI: 10.1016/J.Bioorg.2009.11.004 |
0.789 |
|
2010 |
Knuckley B, Causey CP, Pellechia PJ, Cook PF, Thompson PR. Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): Evidence that general acid catalysis promotes efficient inactivation Chembiochem. 11: 161-165. PMID 20014086 DOI: 10.1002/Cbic.200900698 |
0.816 |
|
2009 |
Jones JE, Causey CP, Knuckley B, Slack-Noyes JL, Thompson PR. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential Current Opinion in Drug Discovery and Development. 12: 616-627. PMID 19736621 |
0.798 |
|
2008 |
Causey CP, Thompson PR. An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4). Tetrahedron Letters. 49: 4383-4385. PMID 19587776 DOI: 10.1016/J.Tetlet.2008.05.021 |
0.742 |
|
2008 |
Arnesen T, Thompson PR, Varhaug JE, Lillehaug JR. The protein acetyltransferase ARD1: a novel cancer drug target? Current Cancer Drug Targets. 8: 545-53. PMID 18991565 DOI: 10.2174/156800908786241113 |
0.402 |
|
2008 |
Obianyo O, Osborne TC, Thompson PR. Kinetic mechanism of protein arginine methyltransferase 1. Biochemistry. 47: 10420-7. PMID 18771293 DOI: 10.1021/Bi800904M |
0.442 |
|
2008 |
Li P, Yao H, Zhang Z, Li M, Luo Y, Thompson PR, Gilmour DS, Wang Y. Regulation of p53 target gene expression by peptidylarginine deiminase 4. Molecular and Cellular Biology. 28: 4745-58. PMID 18505818 DOI: 10.1128/Mcb.01747-07 |
0.315 |
|
2008 |
Yao H, Li P, Venters BJ, Zheng S, Thompson PR, Pugh BF, Wang Y. Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis. The Journal of Biological Chemistry. 283: 20060-8. PMID 18499678 DOI: 10.1074/Jbc.M802940200 |
0.341 |
|
2008 |
Osborne T, Roska RL, Rajski SR, Thompson PR. In situ generation of a bisubstrate analogue for protein arginine methyltransferase 1. Journal of the American Chemical Society. 130: 4574-5. PMID 18338885 DOI: 10.1021/Ja077104V |
0.416 |
|
2008 |
Liu X, Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R, Cole PA. The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature. 451: 846-50. PMID 18273021 DOI: 10.1038/Nature06546 |
0.521 |
|
2008 |
Knuckley B, Luo Y, Thompson PR. Profiling Protein Arginine Deiminase 4 (PAD4): A novel screen to identify PAD4 inhibitors Bioorganic and Medicinal Chemistry. 16: 739-745. PMID 17964793 DOI: 10.1016/J.Bmc.2007.10.021 |
0.752 |
|
2007 |
Osborne TC, Obianyo O, Zhang X, Cheng X, Thompson PR. Protein arginine methyltransferase 1: positively charged residues in substrate peptides distal to the site of methylation are important for substrate binding and catalysis. Biochemistry. 46: 13370-81. PMID 17960915 DOI: 10.1021/Bi701558T |
0.431 |
|
2007 |
Zou Y, Broughton DL, Bicker KL, Thompson PR, Lavigne JJ. Peptide borono lectins (PBLs): a new tool for glycomics and cancer diagnostics. Chembiochem : a European Journal of Chemical Biology. 8: 2048-51. PMID 17924602 DOI: 10.1002/Cbic.200700221 |
0.704 |
|
2007 |
Hwang Y, Thompson PR, Wang L, Jiang L, Kelleher NL, Cole PA. A selective chemical probe for coenzyme A-requiring enzymes. Angewandte Chemie (International Ed. in English). 46: 7621-4. PMID 17768748 DOI: 10.1002/Anie.200702485 |
0.495 |
|
2007 |
Knuckley B, Bhatia M, Thompson PR. Protein arginine deiminase 4: Evidence for a reverse protonation mechanism Biochemistry. 46: 6578-6587. PMID 17497940 DOI: 10.1021/Bi700095S |
0.773 |
|
2007 |
Bhatia M, Thompson PR. Methyllysine analogs: rewriting the code. Nature Chemical Biology. 3: 249-50. PMID 17438548 DOI: 10.1038/Nchembio0507-249 |
0.322 |
|
2007 |
Bhatia M, Thompson PR. Kinetic characterization and substrate specificity studies of Protein Arginine Deiminase 4 (PAD4) The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A642 |
0.425 |
|
2006 |
Thompson PR, Fast W. Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock? Acs Chemical Biology. 1: 433-41. PMID 17168521 DOI: 10.1021/Cb6002306 |
0.427 |
|
2006 |
Luo Y, Knuckley B, Bhatia M, Pellechia PJ, Thompson PR. Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): Synthesis and in vitro evaluation of a fluorescently labeled probe Journal of the American Chemical Society. 128: 14468-14469. PMID 17090024 DOI: 10.1021/Ja0656907 |
0.764 |
|
2006 |
Luo Y, Arita K, Bhatia M, Knuckley B, Lee YH, Stallcup MR, Sato M, Thompson PR. Inhibitors and inactivators of protein arginine deiminase 4: Functional and structural characterization Biochemistry. 45: 11727-11736. PMID 17002273 DOI: 10.1021/Bi061180D |
0.764 |
|
2006 |
Luo Y, Knuckley B, Lee YH, Stallcup MR, Thompson PR. A fluoroacetamidine-based inactivator of protein arginine deiminase 4: Design, synthesis, and in vitro and in vivo evaluation Journal of the American Chemical Society. 128: 1092-1093. PMID 16433522 DOI: 10.1021/Ja0576233 |
0.756 |
|
2006 |
Arita K, Luo Y, Thompson P, Shimizu T, Hashimoto H, Hidaka Y, Yamada M, Sato M. 1P024 Structural basis for histone recognition and inhibition mechanism of human peptidylarginine deiminase 4(1. Protein structure and dynamics (I),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) Seibutsu Butsuri. 46. DOI: 10.2142/Biophys.46.S152_4 |
0.32 |
|
2005 |
Kearney PL, Bhatia M, Jones NG, Yuan L, Glascock MC, Catchings KL, Yamada M, Thompson PR. Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis. Biochemistry. 44: 10570-82. PMID 16060666 DOI: 10.1021/Bi050292M |
0.437 |
|
2005 |
Wang D, Thompson P, Cole PA, Cotter RJ. Structural analysis of a highly acetylated protein using a curved-field reflectron mass spectrometer. Proteomics. 5: 2288-96. PMID 15887180 DOI: 10.1002/Pmic.200401167 |
0.457 |
|
2004 |
Sagar V, Zheng W, Thompson PR, Cole PA. Bisubstrate analogue structure-activity relationships for p300 histone acetyltransferase inhibitors. Bioorganic & Medicinal Chemistry. 12: 3383-90. PMID 15158807 DOI: 10.1016/J.Bmc.2004.03.070 |
0.554 |
|
2004 |
Thompson PR, Wang D, Wang L, Fulco M, Pediconi N, Zhang D, An W, Ge Q, Roeder RG, Wong J, Levrero M, Sartorelli V, Cotter RJ, Cole PA. Regulation of the p300 HAT domain via a novel activation loop. Nature Structural & Molecular Biology. 11: 308-15. PMID 15004546 DOI: 10.1038/Nsmb740 |
0.521 |
|
2004 |
Zheng Y, Thompson PR, Cebrat M, Wang L, Devlin MK, Alani RM, Cole PA. Selective HAT inhibitors as mechanistic tools for protein acetylation. Methods in Enzymology. 376: 188-99. PMID 14975306 DOI: 10.1016/S0076-6879(03)76012-1 |
0.597 |
|
2003 |
Cebrat M, Kim CM, Thompson PR, Daugherty M, Cole PA. Synthesis and analysis of potential prodrugs of coenzyme A analogues for the inhibition of the histone acetyltransferase p300. Bioorganic & Medicinal Chemistry. 11: 3307-13. PMID 12837541 DOI: 10.1016/S0968-0896(03)00265-7 |
0.534 |
|
2002 |
Thompson PR, Boehr DD, Berghuis AM, Wright GD. Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop. Biochemistry. 41: 7001-7. PMID 12033933 DOI: 10.1021/Bi0256680 |
0.718 |
|
2001 |
Thompson PR, Cole PA. Probing the mechanism of enzymatic phosphoryl transfer with a chemical trick Proceedings of the National Academy of Sciences of the United States of America. 98: 8170-8171. PMID 11459948 DOI: 10.1073/Pnas.161273998 |
0.496 |
|
2001 |
Thompson PR, Kurooka H, Nakatani Y, Cole PA. Transcriptional coactivator protein p300. Kinetic characterization of its histone acetyltransferase activity. The Journal of Biological Chemistry. 276: 33721-9. PMID 11445580 DOI: 10.1074/Jbc.M104736200 |
0.56 |
|
2001 |
Boehr DD, Thompson PR, Wright GD. Molecular mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: roles of conserved active site residues. The Journal of Biological Chemistry. 276: 23929-36. PMID 11279088 DOI: 10.1074/Jbc.M100540200 |
0.716 |
|
2000 |
DeLaBarre B, Thompson PR, Wright GD, Berghuis AM. Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases. Nature Structural Biology. 7: 238-44. PMID 10700284 DOI: 10.1038/73359 |
0.521 |
|
1999 |
Thompson PR, Schwartzenhauer J, Hughes DW, Berghuis AM, Wright GD. The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance Journal of Biological Chemistry. 274: 30697-30706. PMID 10521458 DOI: 10.1074/Jbc.274.43.30697 |
0.524 |
|
1999 |
Daigle DM, McKay GA, Thompson PR, Wright GD. Aminoglycoside antibiotic phosphotransferases are also serine protein kinases. Chemistry & Biology. 6: 11-8. PMID 9889150 DOI: 10.1016/S1074-5521(99)80016-7 |
0.788 |
|
1999 |
Wright GD, Thompson PR. Aminoglycoside phosphotransferases: proteins, structure, and mechanism Frontiers in Bioscience : a Journal and Virtual Library. 4. PMID 9872733 DOI: 10.2741/Wright |
0.54 |
|
1998 |
Thompson PR, Hughes DW, Cianciotto NP, Wright GD. Spectinomycin kinase from Legionella pneumophila. Characterization of substrate specificity and identification of catalytically important residues. The Journal of Biological Chemistry. 273: 14788-95. PMID 9614079 DOI: 10.1074/Jbc.273.24.14788 |
0.566 |
|
1997 |
Hon WC, McKay GA, Thompson PR, Sweet RM, Yang DSC, Wright GD, Berghuis AM. Structure of an enzyme required for aminoglycoside antibiotic resistance reveals homology to eukaryotic protein kinases Cell. 89: 887-895. PMID 9200607 DOI: 10.1016/S0092-8674(00)80274-3 |
0.551 |
|
1996 |
Thompson PR, Hughes DW, Wright GD. Mechanism of aminoglycoside 3'-phosphotransferase type IIIa: His188 is not a phosphate-accepting residue Chemistry and Biology. 3: 747-755. PMID 8939691 DOI: 10.1016/S1074-5521(96)90251-3 |
0.529 |
|
1996 |
Thompson PR, Hughes DW, Wright GD. Regiospecificity of aminoglycoside phosphotransferase from Enterococci and Staphylococci (APH(3')-IIIa) Biochemistry. 35: 8686-8695. PMID 8679631 DOI: 10.1021/Bi960389W |
0.511 |
|
1994 |
McKay GA, Thompson PR, Wright GD. Broad spectrum aminoglycoside phosphotransferase type III from Enterococcus: Overexpression, purification, and substrate specificity Biochemistry. 33: 6936-6944. PMID 8204627 DOI: 10.1021/Bi00188A024 |
0.534 |
|
Show low-probability matches. |