Sebastian Bonhoeffer - Publications

Affiliations: 
ETH/Uni Zurich, Zürich, Zürich, Switzerland 

164 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Scire J, Huisman JS, Grosu A, Angst DC, Lison A, Li J, Maathuis MH, Bonhoeffer S, Stadler T. estimateR: an R package to estimate and monitor the effective reproductive number. Bmc Bioinformatics. 24: 310. PMID 37568078 DOI: 10.1186/s12859-023-05428-4  0.746
2022 Vasse M, Bonhoeffer S, Frenoy A. Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments. Isme Communications. 2: 80. PMID 37938266 DOI: 10.1038/s43705-022-00157-w  0.778
2022 Huisman JS, Vaughan TG, Egli A, Tschudin-Sutter S, Stadler T, Bonhoeffer S. The effect of sequencing and assembly on the inference of horizontal gene transfer on chromosomal and plasmid phylogenies. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 377: 20210245. PMID 35989605 DOI: 10.1098/rstb.2021.0245  0.513
2022 Huisman JS, Scire J, Angst DC, Li J, Neher RA, Maathuis MH, Bonhoeffer S, Stadler T. Estimation and worldwide monitoring of the effective reproductive number of SARS-CoV-2. Elife. 11. PMID 35938911 DOI: 10.7554/eLife.71345  0.5
2021 Gostic KM, McGough L, Baskerville EB, Abbott S, Joshi K, Tedijanto C, Kahn R, Niehus R, Hay JA, De Salazar PM, Hellewell J, Meakin S, Munday JD, Bosse NI, Sherrat K, ... ... Bonhoeffer S, et al. Correction: Practical considerations for measuring the effective reproductive number, Rt. Plos Computational Biology. 17: e1009679. PMID 34879070 DOI: 10.1371/journal.pcbi.1009679  0.459
2021 Angst DC, Tepekule B, Sun L, Bogos B, Bonhoeffer S. Comparing treatment strategies to reduce antibiotic resistance in an in vitro epidemiological setting. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33766914 DOI: 10.1073/pnas.2023467118  0.451
2020 Gostic KM, McGough L, Baskerville EB, Abbott S, Joshi K, Tedijanto C, Kahn R, Niehus R, Hay JA, De Salazar PM, Hellewell J, Meakin S, Munday JD, Bosse NI, Sherrat K, ... ... Bonhoeffer S, et al. Practical considerations for measuring the effective reproductive number, Rt. Plos Computational Biology. 16: e1008409. PMID 33301457 DOI: 10.1371/journal.pcbi.1008409  0.525
2020 Benz F, Huisman JS, Bakkeren E, Herter JA, Stadler T, Ackermann M, Diard M, Egli A, Hall AR, Hardt WD, Bonhoeffer S. Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo. The Isme Journal. PMID 33149210 DOI: 10.1038/s41396-020-00819-4  0.74
2020 Gostic KM, McGough L, Baskerville E, Abbott S, Joshi K, Tedijanto C, Kahn R, Niehus R, Hay JA, De Salazar PM, Hellewell J, Meakin S, Munday J, Bosse N, Sherratt K, ... ... Bonhoeffer S, et al. Practical considerations for measuring the effective reproductive number, Rt. Medrxiv : the Preprint Server For Health Sciences. PMID 32607522 DOI: 10.1101/2020.06.18.20134858  0.51
2019 Tepekule B, Abel Zur Wiesch P, Kouyos RD, Bonhoeffer S. Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota. Proceedings of the National Academy of Sciences of the United States of America. PMID 31666328 DOI: 10.1073/Pnas.1912188116  0.344
2019 Sun L, Ashcroft P, Ackermann M, Bonhoeffer S. Stochastic gene expression influences the selection of antibiotic resistance mutations. Molecular Biology and Evolution. PMID 31504754 DOI: 10.1093/Molbev/Msz199  0.756
2019 Bakkeren E, Huisman JS, Fattinger SA, Hausmann A, Furter M, Egli A, Slack E, Sellin ME, Bonhoeffer S, Regoes RR, Diard M, Hardt WD. Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut. Nature. 573: 276-280. PMID 31485077 DOI: 10.1038/S41586-019-1521-8  0.324
2018 Frenoy A, Bonhoeffer S. Death and population dynamics affect mutation rate estimates and evolvability under stress in bacteria. Plos Biology. 16: e2005056. PMID 29750784 DOI: 10.1371/Journal.Pbio.2005056  0.773
2018 Hozé N, Bonhoeffer S, Regoes R. Assessing the public health impact of tolerance-based therapies with mathematical models. Plos Computational Biology. 14: e1006119. PMID 29727455 DOI: 10.1371/Journal.Pcbi.1006119  0.316
2018 Sun L, Alexander HK, Bogos B, Kiviet DJ, Ackermann M, Bonhoeffer S. Effective polyploidy causes phenotypic delay and influences bacterial evolvability. Plos Biology. 16: e2004644. PMID 29470493 DOI: 10.1371/Journal.Pbio.2004644  0.759
2018 Kühnert D, Kouyos R, Shirreff G, Pečerska J, Scherrer AU, Böni J, Yerly S, Klimkait T, Aubert V, Günthard HF, Stadler T, Bonhoeffer S. Quantifying the fitness cost of HIV-1 drug resistance mutations through phylodynamics. Plos Pathogens. 14: e1006895. PMID 29462208 DOI: 10.1371/Journal.Ppat.1006895  0.627
2017 Bertels F, Marzel A, Leventhal G, Mitov V, Fellay J, Günthard HF, Böni J, Yerly S, Klimkait T, Aubert V, Battegay M, Rauch A, Cavassini M, Calmy A, Bernasconi E, ... ... Bonhoeffer S, et al. Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T Cell Decline and Per-Parasite Pathogenicity. Molecular Biology and Evolution. PMID 29029206 DOI: 10.1093/Molbev/Msx246  0.343
2017 Uecker H, Bonhoeffer S. Modeling antimicrobial cycling and mixing: Differences arising from an individual-based versus a population-based perspective. Mathematical Biosciences. PMID 28962827 DOI: 10.1016/J.Mbs.2017.09.002  0.323
2017 Allen RC, Engelstädter J, Bonhoeffer S, McDonald BA, Hall AR. Reversing resistance: different routes and common themes across pathogens. Proceedings. Biological Sciences. 284. PMID 28954914 DOI: 10.1098/Rspb.2017.1619  0.345
2017 Tepekule B, Uecker H, Derungs I, Frenoy A, Bonhoeffer S. Modeling antibiotic treatment in hospitals: A systematic approach shows benefits of combination therapy over cycling, mixing, and mono-drug therapies. Plos Computational Biology. 13: e1005745. PMID 28915236 DOI: 10.1371/Journal.Pcbi.1005745  0.776
2017 Liechti JI, Leventhal GE, Bonhoeffer S. Host population structure impedes reversion to drug sensitivity after discontinuation of treatment. Plos Computational Biology. 13: e1005704. PMID 28827796 DOI: 10.1371/Journal.Pcbi.1005704  0.381
2017 Shilaih M, Angst DC, Marzel A, Bonhoeffer S, Günthard HF, Kouyos RD. Antibacterial effects of antiretrovirals, potential implications for microbiome studies in HIV. Antiviral Therapy. PMID 28497768 DOI: 10.3851/Imp3173  0.328
2017 Mikaberidze A, Paveley N, Bonhoeffer S, van den Bosch F. Emergence of resistance to fungicides: the role of fungicide dose. Phytopathology. PMID 28079455 DOI: 10.1094/Phyto-08-16-0297-R  0.352
2017 Fingerhuth SM, Low N, Bonhoeffer S, Althaus CL. P3.212 Antibiotic resistance detection is essential for gonorrhoea point-of-care testing: a mathematical modelling study Sexually Transmitted Infections. 93. DOI: 10.1136/Sextrans-2017-053264.447  0.305
2016 Alexander HK, Mayer SI, Bonhoeffer S. Population heterogeneity in mutation rate increases the frequency of higher-order mutants and reduces long-term mutational load. Molecular Biology and Evolution. PMID 27836985 DOI: 10.1093/Molbev/Msw244  0.325
2016 Polster R, Petropoulos CJ, Bonhoeffer S, Guillaume F. Epistasis and pleiotropy affect the modularity of the genotype-phenotype map of cross-resistance in HIV-1. Molecular Biology and Evolution. PMID 27678053 DOI: 10.1093/Molbev/Msw206  0.335
2016 Fingerhuth SM, Bonhoeffer S, Low N, Althaus CL. Antibiotic-Resistant Neisseria gonorrhoeae Spread Faster with More Treatment, Not More Sexual Partners. Plos Pathogens. 12: e1005611. PMID 27196299 DOI: 10.1371/Journal.Ppat.1005611  0.337
2016 Leventhal GE, Bonhoeffer S. Potential Pitfalls in Estimating Viral Load Heritability. Trends in Microbiology. PMID 27185643 DOI: 10.1016/J.Tim.2016.04.008  0.321
2016 Legros M, Bonhoeffer S. A combined within-host and between-hosts modelling framework for the evolution of resistance to antimalarial drugs. Journal of the Royal Society, Interface / the Royal Society. 13. PMID 27075004 DOI: 10.1098/Rsif.2016.0148  0.366
2016 Nagaraja P, Alexander HK, Bonhoeffer S, Dixit NM. Influence of recombination on acquisition and reversion of immune escape and compensatory mutations in HIV-1. Epidemics. 14: 11-25. PMID 26972510 DOI: 10.1016/J.Epidem.2015.09.001  0.355
2016 Cadosch D, Abel Zur Wiesch P, Kouyos R, Bonhoeffer S. The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB. Plos Computational Biology. 12: e1004749. PMID 26967493 DOI: 10.1371/Journal.Pcbi.1004749  0.309
2015 Frost SD, Pybus OG, Gog JR, Viboud C, Bonhoeffer S, Bedford T. Eight challenges in phylodynamic inference. Epidemics. 10: 88-92. PMID 25843391 DOI: 10.1016/J.Epidem.2014.09.001  0.338
2015 Yang WL, Kouyos RD, Böni J, Yerly S, Klimkait T, Aubert V, Scherrer AU, Shilaih M, Hinkley T, Petropoulos C, Bonhoeffer S, Günthard HF. Persistence of transmitted HIV-1 drug resistance mutations associated with fitness costs and viral genetic backgrounds. Plos Pathogens. 11: e1004722. PMID 25798934 DOI: 10.1371/Journal.Ppat.1004722  0.363
2015 Fu F, Nowak MA, Bonhoeffer S. Spatial heterogeneity in drug concentrations can facilitate the emergence of resistance to cancer therapy. Plos Computational Biology. 11: e1004142. PMID 25789469 DOI: 10.1371/Journal.Pcbi.1004142  0.59
2015 Bonhoeffer S, Fraser C, Leventhal GE. High heritability is compatible with the broad distribution of set point viral load in HIV carriers. Plos Pathogens. 11: e1004634. PMID 25658741 DOI: 10.1371/Journal.Ppat.1004634  0.347
2015 Leventhal GE, Hill AL, Nowak MA, Bonhoeffer S. Evolution and emergence of infectious diseases in theoretical and real-world networks. Nature Communications. 6: 6101. PMID 25592476 DOI: 10.1038/Ncomms7101  0.687
2015 Vuilleumier S, Bonhoeffer S. Contribution of recombination to the evolutionary history of HIV. Current Opinion in Hiv and Aids. 10: 84-9. PMID 25565174 DOI: 10.1097/Coh.0000000000000137  0.337
2015 Fingerhuth S, Bonhoeffer S, Low N, Althaus C. 001.1 Evolution and spread of antibiotic-resistant gonorrhoea Sexually Transmitted Infections. 91: A25.1-A25. DOI: 10.1136/Sextrans-2015-052270.79  0.339
2014 Alexander HK, Martin G, Martin OY, Bonhoeffer S. Evolutionary rescue: linking theory for conservation and medicine. Evolutionary Applications. 7: 1161-79. PMID 25558278 DOI: 10.1111/Eva.12221  0.327
2014 Boskova V, Bonhoeffer S, Stadler T. Inference of epidemiological dynamics based on simulated phylogenies using birth-death and coalescent models. Plos Computational Biology. 10: e1003913. PMID 25375100 DOI: 10.1371/Journal.Pcbi.1003913  0.589
2014 Kouyos RD, Metcalf CJ, Birger R, Klein EY, Abel zur Wiesch P, Ankomah P, Arinaminpathy N, Bogich TL, Bonhoeffer S, Brower C, Chi-Johnston G, Cohen T, Day T, Greenhouse B, Huijben S, et al. The path of least resistance: aggressive or moderate treatment? Proceedings. Biological Sciences / the Royal Society. 281: 20140566. PMID 25253451 DOI: 10.1098/Rspb.2014.0566  0.34
2014 Abel zur Wiesch P, Kouyos R, Abel S, Viechtbauer W, Bonhoeffer S. Cycling empirical antibiotic therapy in hospitals: meta-analysis and models. Plos Pathogens. 10: e1004225. PMID 24968123 DOI: 10.1371/Journal.Ppat.1004225  0.354
2014 Moradigaravand D, Kouyos R, Hinkley T, Haddad M, Petropoulos CJ, Engelstädter J, Bonhoeffer S. Recombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1. Plos Genetics. 10: e1004439. PMID 24967626 DOI: 10.1371/Journal.Pgen.1004439  0.386
2014 Ocampo PS, Lázár V, Papp B, Arnoldini M, Abel zur Wiesch P, Busa-Fekete R, Fekete G, Pál C, Ackermann M, Bonhoeffer S. Antagonism between bacteriostatic and bactericidal antibiotics is prevalent. Antimicrobial Agents and Chemotherapy. 58: 4573-82. PMID 24867991 DOI: 10.1128/Aac.02463-14  0.716
2014 Avila D, Keiser O, Egger M, Kouyos R, Böni J, Yerly S, Klimkait T, Vernazza PL, Aubert V, Rauch A, Bonhoeffer S, Günthard HF, Stadler T, Spycher BD. Social meets molecular: Combining phylogenetic and latent class analyses to understand HIV-1 transmission in Switzerland. American Journal of Epidemiology. 179: 1514-25. PMID 24821749 DOI: 10.1093/Aje/Kwu076  0.564
2014 Tazzyman SJ, Bonhoeffer S. Plasmids and evolutionary rescue by drug resistance. Evolution; International Journal of Organic Evolution. 68: 2066-78. PMID 24749717 DOI: 10.1111/Evo.12423  0.353
2014 Fraser C, Lythgoe K, Leventhal GE, Shirreff G, Hollingsworth TD, Alizon S, Bonhoeffer S. Virulence and pathogenesis of HIV-1 infection: an evolutionary perspective. Science (New York, N.Y.). 343: 1243727. PMID 24653038 DOI: 10.1126/Science.1243727  0.385
2014 Leventhal GE, Günthard HF, Bonhoeffer S, Stadler T. Using an epidemiological model for phylogenetic inference reveals density dependence in HIV transmission. Molecular Biology and Evolution. 31: 6-17. PMID 24085839 DOI: 10.1093/Molbev/Mst172  0.613
2014 Mikaberidze A, McDonald BA, Bonhoeffer S. Can high-risk fungicides be used in mixtures without selecting for fungicide resistance? Phytopathology. 104: 324-31. PMID 24025048 DOI: 10.1094/Phyto-07-13-0204-R  0.305
2013 Hool A, Leventhal GE, Bonhoeffer S. Virus-induced target cell activation reconciles set-point viral load heritability and within-host evolution. Epidemics. 5: 174-80. PMID 24267873 DOI: 10.1016/J.Epidem.2013.09.002  0.354
2013 Oña L, Kouyos RD, Lachmann M, Bonhoeffer S. On the role of resonance in drug failure under HIV treatment interruption. Theoretical Biology & Medical Modelling. 10: 44. PMID 23844869 DOI: 10.1186/1742-4682-10-44  0.371
2013 Saenz RA, Bonhoeffer S. Nested model reveals potential amplification of an HIV epidemic due to drug resistance. Epidemics. 5: 34-43. PMID 23438429 DOI: 10.1016/J.Epidem.2012.11.002  0.408
2013 Stadler T, Bonhoeffer S. Uncovering epidemiological dynamics in heterogeneous host populations using phylogenetic methods. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120198. PMID 23382421 DOI: 10.1098/Rstb.2012.0198  0.591
2013 Stadler T, Kühnert D, Bonhoeffer S, Drummond AJ. Birth-death skyline plot reveals temporal changes of epidemic spread in HIV and hepatitis C virus (HCV). Proceedings of the National Academy of Sciences of the United States of America. 110: 228-33. PMID 23248286 DOI: 10.1073/Pnas.1207965110  0.587
2012 Alexander HK, Bonhoeffer S. Pre-existence and emergence of drug resistance in a generalized model of intra-host viral dynamics. Epidemics. 4: 187-202. PMID 23351371 DOI: 10.1016/J.Epidem.2012.10.001  0.42
2012 Arnoldini M, Mostowy R, Bonhoeffer S, Ackermann M. Evolution of stress response in the face of unreliable environmental signals. Plos Computational Biology. 8: e1002627. PMID 22916000 DOI: 10.1371/Journal.Pcbi.1002627  0.7
2012 Mostowy R, Kouyos RD, Hoof I, Hinkley T, Haddad M, Whitcomb JM, Petropoulos CJ, Ke?mir C, Bonhoeffer S. Estimating the fitness cost of escape from HLA presentation in HIV-1 protease and reverse transcriptase. Plos Computational Biology. 8: e1002525. PMID 22654656 DOI: 10.1371/Journal.Pcbi.1002525  0.314
2012 Cadosch D, Bonhoeffer S, Kouyos R. Assessing the impact of adherence to anti-retroviral therapy on treatment failure and resistance evolution in HIV. Journal of the Royal Society, Interface / the Royal Society. 9: 2309-20. PMID 22417909 DOI: 10.1098/Rsif.2012.0127  0.403
2012 Kouyos RD, Leventhal GE, Hinkley T, Haddad M, Whitcomb JM, Petropoulos CJ, Bonhoeffer S. Exploring the complexity of the HIV-1 fitness landscape. Plos Genetics. 8: e1002551. PMID 22412384 DOI: 10.1371/Journal.Pgen.1002551  0.355
2012 Leventhal GE, Kouyos R, Stadler T, Wyl Vv, Yerly S, Böni J, Cellerai C, Klimkait T, Günthard HF, Bonhoeffer S. Inferring epidemic contact structure from phylogenetic trees. Plos Computational Biology. 8: e1002413. PMID 22412361 DOI: 10.1371/Journal.Pcbi.1002413  0.566
2012 Stadler T, Kouyos R, von Wyl V, Yerly S, Böni J, Bürgisser P, Klimkait T, Joos B, Rieder P, Xie D, Günthard HF, Drummond AJ, Bonhoeffer S. Estimating the basic reproductive number from viral sequence data. Molecular Biology and Evolution. 29: 347-57. PMID 21890480 DOI: 10.1093/Molbev/Msr217  0.606
2012 Legros M, Bonhoeffer S. Evolution of drug resistance in malaria parasites Malaria Journal. 11. DOI: 10.1186/1475-2875-11-S1-P63  0.336
2011 Kouyos RD, von Wyl V, Hinkley T, Petropoulos CJ, Haddad M, Whitcomb JM, Böni J, Yerly S, Cellerai C, Klimkait T, Günthard HF, Bonhoeffer S. Assessing predicted HIV-1 replicative capacity in a clinical setting. Plos Pathogens. 7: e1002321. PMID 22072960 DOI: 10.1371/Journal.Ppat.1002321  0.358
2011 Kouyos RD, Abel Zur Wiesch P, Bonhoeffer S. On being the right size: the impact of population size and stochastic effects on the evolution of drug resistance in hospitals and the community. Plos Pathogens. 7: e1001334. PMID 21533212 DOI: 10.1371/Journal.Ppat.1001334  0.311
2011 Hinkley T, Martins J, Chappey C, Haddad M, Stawiski E, Whitcomb JM, Petropoulos CJ, Bonhoeffer S. A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase. Nature Genetics. 43: 487-9. PMID 21441930 DOI: 10.1038/Ng.795  0.399
2011 Kouyos RD, Abel Zur Wiesch P, Bonhoeffer S. Informed switching strongly decreases the prevalence of antibiotic resistance in hospital wards. Plos Computational Biology. 7: e1001094. PMID 21390265 DOI: 10.1371/Journal.Pcbi.1001094  0.328
2011 zur Wiesch PA, Kouyos R, Engelstädter J, Regoes RR, Bonhoeffer S. Population biological principles of drug-resistance evolution in infectious diseases. The Lancet. Infectious Diseases. 11: 236-47. PMID 21371657 DOI: 10.1016/S1473-3099(10)70264-4  0.38
2011 Mostowy R, Kouyos RD, Fouchet D, Bonhoeffer S. The role of recombination for the coevolutionary dynamics of HIV and the immune response. Plos One. 6: e16052. PMID 21364750 DOI: 10.1371/Journal.Pone.0016052  0.369
2011 Kouyos RD, von Wyl V, Yerly S, Böni J, Rieder P, Joos B, Taffé P, Shah C, Bürgisser P, Klimkait T, Weber R, Hirschel B, Cavassini M, Rauch A, Battegay M, ... ... Bonhoeffer S, et al. Ambiguous nucleotide calls from population-based sequencing of HIV-1 are a marker for viral diversity and the age of infection. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 52: 532-9. PMID 21220770 DOI: 10.1093/Cid/Ciq164  0.364
2010 Martins JZ, Chappey C, Haddad M, Whitcomb JM, Stawiski E, Petropoulos CJ, Bonhoeffer S. Principal component analysis of general patterns of HIV-1 replicative fitness in different drug environments. Epidemics. 2: 85-91. PMID 21352778 DOI: 10.1016/J.Epidem.2010.03.003  0.375
2010 Alizon S, von Wyl V, Stadler T, Kouyos RD, Yerly S, Hirschel B, Böni J, Shah C, Klimkait T, Furrer H, Rauch A, Vernazza PL, Bernasconi E, Battegay M, Bürgisser P, ... ... Bonhoeffer S, et al. Phylogenetic approach reveals that virus genotype largely determines HIV set-point viral load. Plos Pathogens. 6: e1001123. PMID 20941398 DOI: 10.1371/Journal.Ppat.1001123  0.624
2010 Kouyos RD, von Wyl V, Yerly S, Böni J, Taffé P, Shah C, Bürgisser P, Klimkait T, Weber R, Hirschel B, Cavassini M, Furrer H, Battegay M, Vernazza PL, Bernasconi E, ... ... Bonhoeffer S, et al. Molecular epidemiology reveals long-term changes in HIV type 1 subtype B transmission in Switzerland. The Journal of Infectious Diseases. 201: 1488-97. PMID 20384495 DOI: 10.1086/651951  0.31
2010 Schulz zur Wiesch P, Engelstädter J, Bonhoeffer S. Compensation of fitness costs and reversibility of antibiotic resistance mutations. Antimicrobial Agents and Chemotherapy. 54: 2085-95. PMID 20176903 DOI: 10.1128/Aac.01460-09  0.331
2009 Kouyos RD, Fouchet D, Bonhoeffer S. Recombination and drug resistance in HIV: population dynamics and stochasticity. Epidemics. 1: 58-69. PMID 21352751 DOI: 10.1016/J.Epidem.2008.11.001  0.402
2009 Misevic D, Kouyos RD, Bonhoeffer S. Predicting the evolution of sex on complex fitness landscapes. Plos Computational Biology. 5: e1000510. PMID 19763171 DOI: 10.1371/Journal.Pcbi.1000510  0.733
2009 Müller V, von Wyl V, Yerly S, Böni J, Klimkait T, Bürgisser P, Ledergerber B, Günthard HF, Bonhoeffer S. African descent is associated with slower CD4 cell count decline in treatment-naive patients of the Swiss HIV Cohort Study. Aids (London, England). 23: 1269-76. PMID 19461503 DOI: 10.1097/Qad.0B013E32832D4096  0.314
2009 Novak M, Pfeiffer T, Ackermann M, Bonhoeffer S. Bacterial growth properties at low optical densities. Antonie Van Leeuwenhoek. 96: 267-74. PMID 19390987 DOI: 10.1007/S10482-009-9342-7  0.701
2009 von Wyl V, Yerly S, Bürgisser P, Klimkait T, Battegay M, Bernasconi E, Cavassini M, Furrer H, Hirschel B, Vernazza PL, Francioli P, Bonhoeffer S, Ledergerber B, Günthard HF. Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment-experienced patients in Switzerland. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 48: 979-87. PMID 19228107 DOI: 10.1086/597352  0.377
2009 Magnus C, Rusert P, Bonhoeffer S, Trkola A, Regoes RR. Estimating the stoichiometry of human immunodeficiency virus entry. Journal of Virology. 83: 1523-31. PMID 19019953 DOI: 10.1128/Jvi.01764-08  0.351
2009 Kouyos RD, Salathé M, Otto SP, Bonhoeffer S. The role of epistasis on the evolution of recombination in host-parasite coevolution. Theoretical Population Biology. 75: 1-13. PMID 18957303 DOI: 10.1016/J.Tpb.2008.09.007  0.301
2008 Marconi V, Bonhoeffer S, Paredes R, Lu J, Hoh R, Martin JN, Deeks SG, Kuritzkes DR. Viral dynamics and in vivo fitness of HIV-1 in the presence and absence of enfuvirtide. Journal of Acquired Immune Deficiency Syndromes (1999). 48: 572-6. PMID 18645515 DOI: 10.1097/Qai.0B013E31817Bbc4E  0.383
2008 Salathé M, Kouyos RD, Regoes RR, Bonhoeffer S. Rapid parasite adaptation drives selection for high recombination rates. Evolution; International Journal of Organic Evolution. 62: 295-300. PMID 18039325 DOI: 10.1111/J.1558-5646.2007.00265.X  0.311
2007 Kouyos RD, Salathé M, Bonhoeffer S. The Red Queen and the persistence of linkage-disequilibrium oscillations in finite and infinite populations. Bmc Evolutionary Biology. 7: 211. PMID 17986336 DOI: 10.1186/1471-2148-7-211  0.309
2007 Débarre F, Bonhoeffer S, Regoes RR. The effect of population structure on the emergence of drug resistance during influenza pandemics. Journal of the Royal Society, Interface / the Royal Society. 4: 893-906. PMID 17609176 DOI: 10.1098/Rsif.2007.1126  0.363
2007 Kouyos RD, Silander OK, Bonhoeffer S. Epistasis between deleterious mutations and the evolution of recombination. Trends in Ecology & Evolution. 22: 308-15. PMID 17337087 DOI: 10.1016/J.Tree.2007.02.014  0.327
2006 Soyer OS, Bonhoeffer S. Evolution of complexity in signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 103: 16337-42. PMID 17060629 DOI: 10.1073/Pnas.0604449103  0.623
2006 Kouyos RD, Althaus CL, Bonhoeffer S. Stochastic or deterministic: what is the effective population size of HIV-1? Trends in Microbiology. 14: 507-11. PMID 17049239 DOI: 10.1016/J.Tim.2006.10.001  0.335
2006 Brandin E, Thorstensson R, Bonhoeffer S, Albert J. Rapid viral decay in simian immunodeficiency virus-infected macaques receiving quadruple antiretroviral therapy. Journal of Virology. 80: 9861-4. PMID 16973590 DOI: 10.1128/Jvi.00394-06  0.349
2006 Novak M, Pfeiffer T, Lenski RE, Sauer U, Bonhoeffer S. Experimental tests for an evolutionary trade-off between growth rate and yield in E. coli. The American Naturalist. 168: 242-51. PMID 16874633 DOI: 10.1086/506527  0.642
2006 Funk GA, Oxenius A, Fischer M, Opravil M, Joos B, Flepp M, Weber R, Günthard HF, Bonhoeffer S. HIV replication elicits little cytopathic effects in vivo: analysis of surrogate markers for virus production, cytotoxic T cell response and infected cell death. Journal of Medical Virology. 78: 1141-6. PMID 16847964 DOI: 10.1002/Jmv.20674  0.35
2006 Regoes RR, Bowen EF, Cope AV, Gor D, Hassan-Walker AF, Prentice HG, Johnson MA, Sweny P, Burroughs AK, Griffiths PD, Bonhoeffer S, Emery VC. Modelling cytomegalovirus replication patterns in the human host: factors important for pathogenesis. Proceedings. Biological Sciences / the Royal Society. 273: 1961-7. PMID 16822758 DOI: 10.1098/Rspb.2006.3506  0.303
2006 Regoes RR, Bonhoeffer S. Emergence of drug-resistant influenza virus: population dynamical considerations. Science (New York, N.Y.). 312: 389-91. PMID 16627735 DOI: 10.1126/Science.1122947  0.371
2006 Müller V, Ledergerber B, Perrin L, Klimkait T, Furrer H, Telenti A, Bernasconi E, Vernazza P, Günthard HF, Bonhoeffer S. Stable virulence levels in the HIV epidemic of Switzerland over two decades. Aids (London, England). 20: 889-94. PMID 16549973 DOI: 10.1097/01.Aids.0000218553.51908.6B  0.356
2006 Kouyos RD, Otto SP, Bonhoeffer S. Effect of varying epistasis on the evolution of recombination. Genetics. 173: 589-97. PMID 16547114 DOI: 10.1534/Genetics.105.053108  0.302
2006 Soyer OS, Pfeiffer T, Bonhoeffer S. Simulating the evolution of signal transduction pathways. Journal of Theoretical Biology. 241: 223-32. PMID 16403533 DOI: 10.1016/J.Jtbi.2005.11.024  0.615
2006 Salathé M, Ackermann M, Bonhoeffer S. The effect of multifunctionality on the rate of evolution in yeast. Molecular Biology and Evolution. 23: 721-2. PMID 16380406 DOI: 10.1093/Molbev/Msj086  0.701
2006 Soyer OS, Salathé M, Bonhoeffer S. Signal transduction networks: topology, response and biochemical processes. Journal of Theoretical Biology. 238: 416-25. PMID 16045939 DOI: 10.1016/J.Jtbi.2005.05.030  0.61
2005 Salathé M, May RM, Bonhoeffer S. The evolution of network topology by selective removal. Journal of the Royal Society, Interface / the Royal Society. 2: 533-6. PMID 16849212 DOI: 10.1098/Rsif.2005.0072  0.563
2005 Althaus CL, Bonhoeffer S. Stochastic interplay between mutation and recombination during the acquisition of drug resistance mutations in human immunodeficiency virus type 1. Journal of Virology. 79: 13572-8. PMID 16227277 DOI: 10.1128/Jvi.79.21.13572-13578.2005  0.414
2005 Brandin E, Broström C, Gille E, Bonhoeffer S, Albert J. Short communication: HIV type 2 dynamics. Aids Research and Human Retroviruses. 21: 608-10. PMID 16060831 DOI: 10.1089/Aid.2005.21.608  0.352
2005 Pfeiffer T, Soyer OS, Bonhoeffer S. The evolution of connectivity in metabolic networks. Plos Biology. 3: e228. PMID 16000019 DOI: 10.1371/Journal.Pbio.0030228  0.604
2005 Regoes RR, Bonhoeffer S. The HIV coreceptor switch: a population dynamical perspective. Trends in Microbiology. 13: 269-77. PMID 15936659 DOI: 10.1016/J.Tim.2005.04.005  0.384
2005 Funk GA, Jansen VA, Bonhoeffer S, Killingback T. Spatial models of virus-immune dynamics. Journal of Theoretical Biology. 233: 221-36. PMID 15619362 DOI: 10.1016/J.Jtbi.2004.10.004  0.33
2005 Salathé M, Scherer A, Bonhoeffer S. Neutral drift and polymorphism in gene-for-gene systems Ecology Letters. 8: 925-932. DOI: 10.1111/J.1461-0248.2005.00794.X  0.33
2004 Bonhoeffer S, Chappey C, Parkin NT, Whitcomb JM, Petropoulos CJ. Evidence for positive epistasis in HIV-1. Science (New York, N.Y.). 306: 1547-50. PMID 15567861 DOI: 10.1126/Science.1101786  0.323
2004 Ciuffi A, Bleiber G, Muñoz M, Martinez R, Loeuillet C, Rehr M, Fischer M, Günthard HF, Oxenius A, Meylan P, Bonhoeffer S, Trono D, Telenti A. Entry and transcription as key determinants of differences in CD4 T-cell permissiveness to human immunodeficiency virus type 1 infection. Journal of Virology. 78: 10747-54. PMID 15367641 DOI: 10.1128/Jvi.78.19.10747-10754.2004  0.326
2004 Hersberger M, Bonhoeffer S, Rampini SK, Opravil M, Marti-Jaun J, Telenti A, Hänseler E, Ledergerber B, Speck RF. CCTTT-repeat polymorphism of the inducible nitric oxide synthase is not associated with HIV pathogenesis. Clinical and Experimental Immunology. 137: 566-9. PMID 15320907 DOI: 10.1111/J.1365-2249.2004.02574.X  0.317
2004 Rusert P, Fischer M, Joos B, Leemann C, Kuster H, Flepp M, Bonhoeffer S, Günthard HF, Trkola A. Quantification of infectious HIV-1 plasma viral load using a boosted in vitro infection protocol. Virology. 326: 113-29. PMID 15262500 DOI: 10.1016/J.Virol.2004.05.022  0.343
2004 Trkola A, Kuster H, Leemann C, Oxenius A, Fagard C, Furrer H, Battegay M, Vernazza P, Bernasconi E, Weber R, Hirschel B, Bonhoeffer S, Günthard HF. Humoral immunity to HIV-1: kinetics of antibody responses in chronic infection reflects capacity of immune system to improve viral set point. Blood. 104: 1784-92. PMID 15187026 DOI: 10.1182/Blood-2004-01-0251  0.314
2004 Bretscher MT, Althaus CL, Müller V, Bonhoeffer S. Recombination in HIV and the evolution of drug resistance: for better or for worse? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 26: 180-8. PMID 14745836 DOI: 10.1002/Bies.10386  0.42
2003 Müller V, Bonhoeffer S. Mathematical approaches in the study of viral kinetics and drug resistance in HIV-1 infection. Current Drug Targets. Infectious Disorders. 3: 329-44. PMID 14754433 DOI: 10.2174/1568005033481042  0.405
2003 Trkola A, Kuster H, Leemann C, Ruprecht C, Joos B, Telenti A, Hirschel B, Weber R, Bonhoeffer S, Günthard HF. Human immunodeficiency virus type 1 fitness is a determining factor in viral rebound and set point in chronic infection. Journal of Virology. 77: 13146-55. PMID 14645571 DOI: 10.1128/Jvi.77.24.13146-13155.2003  0.362
2003 Metzner KJ, Bonhoeffer S, Fischer M, Karanicolas R, Allers K, Joos B, Weber R, Hirschel B, Kostrikis LG, Günthard HF. Emergence of minor populations of human immunodeficiency virus type 1 carrying the M184V and L90M mutations in subjects undergoing structured treatment interruptions. The Journal of Infectious Diseases. 188: 1433-43. PMID 14624368 DOI: 10.1086/379215  0.402
2003 Bonhoeffer S, Funk GA, Günthard HF, Fischer M, Müller V. Glancing behind virus load variation in HIV-1 infection. Trends in Microbiology. 11: 499-504. PMID 14607066 DOI: 10.1016/J.Tim.2003.09.002  0.348
2002 Bonhoeffer S, Sniegowski P. Virus evolution: the importance of being erroneous. Nature. 420: 367, 369. PMID 12459766 DOI: 10.1038/420367A  0.328
2002 Bonhoeffer S, Barbour AD, De Boer RJ. Procedures for reliable estimation of viral fitness from time-series data. Proceedings. Biological Sciences / the Royal Society. 269: 1887-93. PMID 12350250 DOI: 10.1098/Rspb.2002.2097  0.393
2002 Regoes R, Bonhoeffer S. HIV coreceptor usage and drug treatment. Journal of Theoretical Biology. 217: 443-57. PMID 12234752 DOI: 10.1006/Jtbi.2002.3049  0.335
2002 Müller V, Vigueras-Gómez JF, Bonhoeffer S. Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection Journal of Virology. 76: 8963-8965. PMID 12163616 DOI: 10.1128/Jvi.76.17.8963-8965.2002  0.336
2002 Regoes RR, Staprans SI, Feinberg MB, Bonhoeffer S. Contribution of peaks of virus load to simian immunodeficiency virus pathogenesis Journal of Virology. 76: 2573-2578. PMID 11836438 DOI: 10.1128/Jvi.76.5.2573-2578.2002  0.319
2002 Ortiz GM, Hu J, Goldwitz JA, Chandwani R, Larsson M, Bhardwaj N, Bonhoeffer S, Ramratnam B, Zhang L, Markowitz MM, Nixon DF. Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection Journal of Virology. 76: 411-415. PMID 11739706 DOI: 10.1128/Jvi.76.1.411-415.2002  0.324
2001 Betts MR, Ambrozak DR, Douek DC, Bonhoeffer S, Brenchley JM, Casazza JP, Koup RA, Picker LJ. Analysis of total human immunodeficiency virus (HIV)-specific CD4+ and CD8+ T-cell responses: Relationship to viral load in untreated HIV infection Journal of Virology. 75: 11983-11991. PMID 11711588 DOI: 10.1128/Jvi.75.24.11983-11991.2001  0.31
2001 García F, Plana M, Ortiz GM, Bonhoeffer S, Soriano A, Vidal C, Cruceta A, Arnedo M, Gil C, Pantaleo G, Pumarola T, Gallart T, Nixon DF, Miró JM, Gatell JM. The virological and immunological consequences of structured treatment interruptions in chronic HIV-1 infection. Aids (London, England). 15: F29-40. PMID 11416735 DOI: 10.1097/00002030-200106150-00002  0.362
2001 Funk GA, Fischer M, Joos B, Opravil M, Günthard HF, Ledergerber B, Bonhoeffer S. Quantification of in vivo replicative capacity of HIV-1 in different compartments of infected cells Journal of Acquired Immune Deficiency Syndromes. 26: 397-404. PMID 11391158 DOI: 10.1097/00126334-200104150-00001  0.358
2000 Bonhoeffer S, Rembiszewski M, Ortiz GM, Nixon DF. Risks and benefits of structured antiretroviral drug therapy interruptions in HIV-1 infection Aids. 14: 2313-2322. PMID 11089619 DOI: 10.1097/00002030-200010200-00012  0.373
2000 Regoes RR, Nowak MA, Bonhoeffer S. Evolution of virulence in a heterogeneous host population Evolution. 54: 64-71. PMID 10937184 DOI: 10.1111/J.0014-3820.2000.Tb00008.X  0.567
2000 Ribeiro RM, Bonhoeffer S. Production of resistant HIV mutants during antiretroviral therapy Proceedings of the National Academy of Sciences of the United States of America. 97: 7681-7686. PMID 10884399 DOI: 10.1073/Pnas.97.14.7681  0.597
2000 Jin X, Demoitie MA, Donahoe SM, Ogg GS, Bonhoeffer S, Kakimoto WM, Gillespie G, Moss PA, Dyer W, Kurilla MG, Riddell SR, Downie J, Sullivan JS, McMichael AJ, Workman C, et al. High frequency of cytomegalovirus-specific cytotoxic T-effector cells in HLA-A*0201-positive subjects during multiple viral coinfectious Journal of Infectious Diseases. 181: 165-175. PMID 10608763 DOI: 10.1086/315201  0.322
1999 Ramratnam B, Bonhoeffer S, Binley J, Hurley A, Zhang L, Mittler JE, Markowitz M, Moore JP, Perelson AS, Ho DD. Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis. Lancet (London, England). 354: 1782-5. PMID 10577640 DOI: 10.1016/S0140-6736(99)02035-8  0.327
1999 Ortiz GM, Nixon DF, Trkola A, Binley J, Jin X, Bonhoeffer S, Kuebler PJ, Donahoe SM, Demoitie MA, Kakimoto WM, Ketas T, Clas B, Heymann JJ, Zhang L, Cao Y, et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of highly active antiretroviral therapy. The Journal of Clinical Investigation. 104: R13-8. PMID 10491418 DOI: 10.1172/Jci7371  0.336
1999 Parkin NT, Lie YS, Hellmann N, Markowitz M, Bonhoeffer S, Ho DD, Petropoulos CJ. Phenotypic changes in drug susceptibility associated with failure of human immunodeficiency virus type 1 (HIV-1) triple combination therapy Journal of Infectious Diseases. 180: 865-870. PMID 10438382 DOI: 10.1086/314928  0.36
1999 Nixon DF, Douek D, Kuebler PJ, Jin X, Vesanen M, Bonhoeffer S, Cao Y, Koup RA, Ho DD, Markowitz M. Molecular tracking of an Human Immunodeficiency Virus nef specific cytotoxic T-cell clone shows persistence of clone-specific T-cell receptor DNA but not mRNA following early combination antiretroviral therapy Immunology Letters. 66: 219-228. PMID 10203058 DOI: 10.1016/S0165-2478(98)00162-X  0.342
1999 Ribeiro RM, Bonhoeffer S. A stochastic model for primary HIV infection: Optimal timing of therapy Aids. 13: 351-357. PMID 10199225 DOI: 10.1097/00002030-199902250-00007  0.62
1999 Levin BR, Lipsitch M, Bonhoeffer S. Population biology, evolution, and infectious disease: convergence and synthesis. Science (New York, N.Y.). 283: 806-9. PMID 9933155 DOI: 10.1126/Science.283.5403.806  0.307
1999 Zhang L, Dailey PJ, He T, Gettie A, Bonhoeffer S, Perelson AS, Ho DD. Rapid clearance of simian immunodeficiency virus particles from plasma of rhesus macaques Journal of Virology. 73: 855-860. PMID 9847402 DOI: 10.1128/Jvi.73.1.855-860.1999  0.345
1999 Ogg GS, Jin X, Bonhoeffer S, Moss P, Nowak MA, Monard S, Segal JP, Cao Y, Rowland-Jones SL, Hurley A, Markowitz M, Ho DD, McMichael AJ, Nixon DF. Decay kinetics of human immunodeficiency virus-specifiic effector cytotoxic T lymphocytes after combination antiretroviral therapy Journal of Virology. 73: 797-800. PMID 9847391 DOI: 10.1128/Jvi.73.1.797-800.1999  0.596
1998 Bonhoeffer S. Models of viral kinetics and drug resistance in HIV-1 infection Aids Patient Care and Stds. 12: 769-774. PMID 11362021 DOI: 10.1089/Apc.1998.12.769  0.391
1998 Morris L, Binley JM, Clas BA, Bonhoeffer S, Astill TP, Kost R, Hurley A, Cao Y, Markowitz M, Ho DD, Moore JP. HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy Journal of Experimental Medicine. 188: 233-245. PMID 9670036 DOI: 10.1084/Jem.188.2.233  0.333
1998 Ribeiro RM, Bonhoeffer S, Nowak MA. The frequency of resistant mutant virus before antiviral therapy Aids. 12: 461-465. PMID 9543443 DOI: 10.1097/00002030-199805000-00006  0.703
1998 Ogg GS, Jin X, Bonhoeffer S, Dunbar PR, Nowak MA, Monard S, Segal JP, Cao Y, Rowland-Jones SL, Cerundolo V, Hurley A, Markowitz M, Ho DD, Nixon DF, McMichael AJ. Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA Science. 279: 2103-2106. PMID 9516110 DOI: 10.1126/Science.279.5359.2103  0.585
1998 Levin BR, Antia R, Berliner E, Bloland P, Bonhoeffer S, Cohen M, DeRouin T, Fields PI, Jafari H, Jernigan D, Lipsitch M, McGowan JE, Mead P, Nowak M, Porco T, et al. Resistance to antimicrobial chemotherapy: a prescription for research and action. The American Journal of the Medical Sciences. 315: 87-94. PMID 9472907 DOI: 10.1016/S0002-9629(15)40282-4  0.583
1998 Mohri H, Bonhoeffer S, Monard S, Perelson AS, Ho DD. Rapid turnover of T lymphocytes in SIV-infected rhesus macaques Science. 279: 1223-1227. PMID 9469816 DOI: 10.1126/Science.279.5354.1223  0.312
1997 Bonhoeffer S, Lipsitch M, Levin BR. Evaluating treatment protocols to prevent antibiotic resistance. Proceedings of the National Academy of Sciences of the United States of America. 94: 12106-11. PMID 9342370 DOI: 10.1073/Pnas.94.22.12106  0.339
1997 Bittner B, Bonhoeffer S, Nowak MA. Virus load and antigenic diversity Bulletin of Mathematical Biology. 59: 881-896. PMID 9281903 DOI: 10.1016/S0092-8240(97)00034-7  0.589
1997 Bonhoeffer S, May RM, Shaw GM, Nowak MA. Virus dynamics and drug therapy. Proceedings of the National Academy of Sciences of the United States of America. 94: 6971-6. PMID 9192676 DOI: 10.1073/Pnas.94.13.6971  0.729
1997 Bonhoeffer S, Nowak MA. Pre-existence and emergence of drug resistance in HIV-1 infection Proceedings of the Royal Society B: Biological Sciences. 264: 631-637. PMID 9178534 DOI: 10.1098/Rspb.1997.0089  0.617
1997 Bonhoeffer S, Coffin JM, Nowak MA. Human immunodeficiency virus drug therapy and virus load. Journal of Virology. 71: 3275-8. PMID 9060694 DOI: 10.1128/Jvi.71.4.3275-3278.1997  0.594
1997 Nowak MA, Bonhoeffer S, Shaw GM, May RM. Anti-viral drug treatment: dynamics of resistance in free virus and infected cell populations. Journal of Theoretical Biology. 184: 203-17. PMID 9059598 DOI: 10.1006/Jtbi.1996.0307  0.737
1996 Bonhoeffer S, Herz AV, Boerlijst MC, Nee S, Nowak MA, May RM. Explaining "linguistic features" of noncoding DNA. Science (New York, N.Y.). 271: 14b-5b. PMID 17798153 DOI: 10.1126/Science.271.5245.14B  0.654
1996 Bonhoeffer S, Herz AV, Boerlijst MC, Nee S, Nowak MA, May RM. No signs of hidden language in noncoding DNA. Physical Review Letters. 76: 1977. PMID 10060572 DOI: 10.1103/Physrevlett.76.1977  0.651
1996 Nowak MA, Anderson RM, Boerlijst MC, Bonhoeffer S, May RM, McMichael AJ. HIV-1 evolution and disease progression. Science (New York, N.Y.). 274: 1008-11. PMID 8966557 DOI: 10.1126/Science.274.5289.1008  0.689
1996 Bonhoeffer S, Lenski RE, Ebert D. The curse of the pharaoh: the evolution of virulence in pathogens with long living propagules. Proceedings. Biological Sciences / the Royal Society. 263: 715-21. PMID 8763793 DOI: 10.1098/Rspb.1996.0107  0.651
1996 Herz AV, Bonhoeffer S, Anderson RM, May RM, Nowak MA. Viral dynamics in vivo: limitations on estimates of intracellular delay and virus decay. Proceedings of the National Academy of Sciences of the United States of America. 93: 7247-51. PMID 8692977 DOI: 10.1073/Pnas.93.14.7247  0.719
1996 Nowak MA, Bonhoeffer S, Hill AM, Boehme R, Thomas HC, McDade H. Viral dynamics in hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 93: 4398-402. PMID 8633078 DOI: 10.1073/Pnas.93.9.4398  0.607
1996 Bonhoeffer S, Herz AV, Boerlijst MC, Nee S, Nowak MA, May RM. Explaining "linguistic features" of noncoding DNA. Science (New York, N.Y.). 271: 14-5. PMID 8539587  0.631
1996 Boerlijst MC, Bonhoeffer S, Nowak MA. Viral quasi-species and recombination Proceedings of the Royal Society B: Biological Sciences. 263: 1577-1584. DOI: 10.1098/Rspb.1996.0231  0.57
1995 Nowak MA, Bonhoeffer S, Loveday C, Balfe P, Semple M, Kaye S, Tenant-Flowers M, Tedder R. HIV results in the frame. Results confirmed Nature. 375: 193. PMID 7746311 DOI: 10.1038/375193A0  0.576
1995 Bonhoeffer S, Nowak MA. Can live attenuated virus work as post-exposure treatment? Immunology Today. 16: 131-135. PMID 7718085 DOI: 10.1016/0167-5699(95)80129-4  0.581
1995 Bonhoeffer S, Holmes EC, Nowak MA. Causes of HIV diversity [3] Nature. 376: 125. PMID 7603560 DOI: 10.1038/376125A0  0.561
1995 Wei X, Ghosh SK, Taylor ME, Johnson VA, Emini EA, Deutsch P, Lifson JD, Bonhoeffer S, Nowak MA, Hahn BH, Saag MS, Shaw GM. Viral dynamics in human immunodeficiency virus type 1 infection Nature. 373: 117-122. PMID 7529365 DOI: 10.1038/373117A0  0.609
1994 Nowak MA, Bonhoeffer S, May RM. Spatial games and the maintenance of cooperation. Proceedings of the National Academy of Sciences of the United States of America. 91: 4877-81. PMID 8197150 DOI: 10.1073/Pnas.91.11.4877  0.669
1994 Bonhoeffer S, Nowak MA. Intra-host versus inter-host selection: Viral strategies of immune function impairment Proceedings of the National Academy of Sciences of the United States of America. 91: 8062-8066. PMID 8058757 DOI: 10.1073/Pnas.91.17.8062  0.579
1994 NOWAK MA, BONHOEFFER S, MAY RM. MORE SPATIAL GAMES International Journal of Bifurcation and Chaos. 4: 33-56. DOI: 10.1142/S0218127494000046  0.537
1994 Bonhoeffer S, Nowak MA. Mutation and the evolution of virulence Proceedings of the Royal Society B: Biological Sciences. 258: 133-140. DOI: 10.1098/Rspb.1994.0153  0.591
1993 Bonhoeffer S, McCaskill JS, Stadler PF, Schuster P. RNA multi-structure landscapes - A study based on temperature dependent partition functions European Biophysics Journal. 22: 13-24. PMID 7685689 DOI: 10.1007/Bf00205808  0.441
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