| Year |
Citation |
Score |
| 2023 |
Romero M, Miller K, Gelsomini A, Garcia D, Li K, Suresh D, Frasca D. Immunometabolic effects of lactate on B cell function in healthy individuals of different ages. Medrxiv : the Preprint Server For Health Sciences. PMID 37609164 DOI: 10.1101/2023.08.07.23293760 |
0.415 |
|
| 2023 |
Frasca D, Romero M, Diaz A, Blomberg BB. Obesity accelerates age defects in B cells, and weight loss improves B cell function. Immunity & Ageing : I & A. 20: 35. PMID 37460937 DOI: 10.1186/s12979-023-00361-9 |
0.3 |
|
| 2023 |
Frasca D, Garcia D, Diaz A, Romero M, Thaller S, Blomberg BB. Phenotypic and functional features of B cells from two different human subcutaneous adipose depots. Plos One. 18: e0285025. PMID 37104286 DOI: 10.1371/journal.pone.0285025 |
0.338 |
|
| 2022 |
Li K, Romero M, Cañardo C, Garcia D, Diaz A, Blomberg BB, Frasca D. B cells from old mice induce the generation of inflammatory T cells through metabolic pathways. Mechanisms of Ageing and Development. 111742. PMID 36309082 DOI: 10.1016/j.mad.2022.111742 |
0.386 |
|
| 2022 |
Frasca D, Romero M, Garcia D, Diaz A, Blomberg BB. Obesity Accelerates Age-Associated Defects in Human B Cells Through a Metabolic Reprogramming Induced by the Fatty Acid Palmitate. Frontiers in Aging. 2: 828697. PMID 35822047 DOI: 10.3389/fragi.2021.828697 |
0.409 |
|
| 2022 |
Frasca D. Obesity Accelerates Age Defects in Human B Cells and Induces Autoimmunity. Immunometabolism. 4. PMID 35433040 DOI: 10.20900/immunometab20220010 |
0.412 |
|
| 2022 |
Frasca D, Pallikkuth S, Pahwa S. Effects of Aging on Metabolic Characteristics of Human B Cells. Journal of Acquired Immune Deficiency Syndromes (1999). 89: S23-S28. PMID 35015742 DOI: 10.1097/QAI.0000000000002860 |
0.361 |
|
| 2021 |
Frasca D, Diaz A, Romero M, Blomberg BB. Metformin Enhances B Cell Function and Antibody Responses of Elderly Individuals With Type-2 Diabetes Mellitus. Frontiers in Aging. 2: 715981. PMID 35822013 DOI: 10.3389/fragi.2021.715981 |
0.417 |
|
| 2021 |
Frasca D, Diaz A, Romero M, Blomberg BB. Phenotypic and Functional Characterization of Double Negative B Cells in the Blood of Individuals With Obesity. Frontiers in Immunology. 12: 616650. PMID 33708209 DOI: 10.3389/fimmu.2021.616650 |
0.316 |
|
| 2021 |
Frasca D, Romero M, Diaz A, Garcia D, Thaller S, Blomberg BB. B Cells with a Senescent-Associated Secretory Phenotype Accumulate in the Adipose Tissue of Individuals with Obesity. International Journal of Molecular Sciences. 22. PMID 33673271 DOI: 10.3390/ijms22041839 |
0.322 |
|
| 2021 |
Frasca D, Romero M, Garcia D, Diaz A, Blomberg BB. Hyper-metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities. Immunity & Ageing : I & A. 18: 9. PMID 33639971 DOI: 10.1186/s12979-021-00222-3 |
0.378 |
|
| 2020 |
Frasca D, Blomberg BB. Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination. Immunity & Ageing : I & A. 17: 37. PMID 33292323 DOI: 10.1186/s12979-020-00210-z |
0.344 |
|
| 2020 |
Frasca D, Diaz A, Romero M, Garcia D, Blomberg BB. B Cell Immunosenescence. Annual Review of Cell and Developmental Biology. 36: 551-574. PMID 33021823 DOI: 10.1146/annurev-cellbio-011620-034148 |
0.415 |
|
| 2020 |
Frasca D, Blomberg BB. Obesity Accelerates Age Defects in Mouse and Human B Cells. Frontiers in Immunology. 11: 2060. PMID 32983154 DOI: 10.3389/Fimmu.2020.02060 |
0.459 |
|
| 2020 |
Frasca D, Blomberg BB. Adipose tissue, immune aging, and cellular senescence. Seminars in Immunopathology. PMID 32785750 DOI: 10.1007/S00281-020-00812-1 |
0.445 |
|
| 2020 |
Cohen AA, Kennedy BK, Anglas U, Bronikowski AM, Deelen J, Dufour F, Ferbeyre G, Ferrucci L, Franceschi C, Frasca D, Friguet B, Gaudreau P, Gladyshev VN, Gonos ES, Gorbunova V, et al. Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework. Mechanisms of Ageing and Development. 111316. PMID 32693105 DOI: 10.1016/J.Mad.2020.111316 |
0.353 |
|
| 2020 |
Frasca D, Blomberg BB, Garcia D, Keilich SR, Haynes L. Age-related factors that affect B cell responses to vaccination in mice and humans. Immunological Reviews. PMID 32484934 DOI: 10.1111/Imr.12864 |
0.488 |
|
| 2020 |
Frasca D, Diaz A, Romero M, Garcia D, Jayram D, Thaller S, Del Carmen Piqueras M, Bhattacharya S, Blomberg BB. Identification and Characterization of Adipose Tissue-Derived Human Antibodies With "Anti-self" Specificity. Frontiers in Immunology. 11: 392. PMID 32184790 DOI: 10.3389/Fimmu.2020.00392 |
0.336 |
|
| 2020 |
Frasca D, Diaz A, Romero M, Vazquez T, Strbo N, Romero L, McCormack RM, Podack ER, Blomberg BB. Impaired B Cell Function in Mice Lacking Perforin-2. Frontiers in Immunology. 11: 328. PMID 32180773 DOI: 10.3389/Fimmu.2020.00328 |
0.499 |
|
| 2020 |
Frasca D, Blomberg BB. Obesity Accelerates Age Defects in Mouse and Human B Cells Frontiers in Immunology. 11. DOI: 10.3389/fimmu.2020.02060 |
0.319 |
|
| 2019 |
Frasca D, Diaz A, Romero M, Blomberg BB. Leptin induces immunosenescence in human B cells. Cellular Immunology. 103994. PMID 31831137 DOI: 10.1016/J.Cellimm.2019.103994 |
0.522 |
|
| 2019 |
Diaz A, Romero M, Frasca D, Blomberg BB. Immunophenotyping of Human B Lymphocytes in Blood and in Adipose Tissue. Methods in Molecular Biology (Clifton, N.J.). 2032: 115-127. PMID 31522416 DOI: 10.1007/978-1-4939-9650-6_7 |
0.494 |
|
| 2019 |
Frasca D, Blomberg BB. Adipose Tissue: A Tertiary Lymphoid Organ: Does It Change with Age? Gerontology. 1-8. PMID 31412335 DOI: 10.1159/000502036 |
0.443 |
|
| 2019 |
Frasca D, Diaz A, Romero M, Thaller S, Blomberg BB. Metabolic requirements of human pro-inflammatory B cells in aging and obesity. Plos One. 14: e0219545. PMID 31287846 DOI: 10.1371/Journal.Pone.0219545 |
0.473 |
|
| 2019 |
Rodriguez Valentin M, Rivas D, Jurecic V, Diaz A, Riley R, Frasca D, Jurecic R. Cellular and Molecular Characterization of Breast Cancer Chemotherapy-Related B Cell Lymphomas Blood. 134: 5241-5241. DOI: 10.1182/Blood-2019-127252 |
0.711 |
|
| 2019 |
Antoni M, Diaz A, Romero M, Frasca D, Blomberg B. Abstract # 2062 Affective status and immune responses to influenza vaccine in older persons living in South Florida Brain, Behavior, and Immunity. 76: e6-e7. DOI: 10.1016/J.Bbi.2018.11.190 |
0.398 |
|
| 2018 |
Pala O, Diaz A, Blomberg BB, Frasca D. B Lymphocytes in Rheumatoid Arthritis and the Effects of Anti-TNF-α Agents on B Lymphocytes: A Review of the Literature. Clinical Therapeutics. PMID 29801753 DOI: 10.1016/J.Clinthera.2018.04.016 |
0.396 |
|
| 2018 |
Frasca D, Diaz A, Romero M, Thaller S, Blomberg BB. Secretion of autoimmune antibodies in the human subcutaneous adipose tissue. Plos One. 13: e0197472. PMID 29768501 DOI: 10.1371/Journal.Pone.0197472 |
0.425 |
|
| 2018 |
Gensous N, Franceschi C, Blomberg BB, Pirazzini C, Ravaioli F, Gentilini D, Di Blasio AM, Garagnani P, Frasca D, Bacalini MG. Responders and non-responders to influenza vaccination: A DNA methylation approach on blood cells. Experimental Gerontology. PMID 29360511 DOI: 10.1016/J.Exger.2018.01.019 |
0.378 |
|
| 2017 |
Frasca D, Blomberg BB, Fuldner R, Prabhudas M. "Aging and immunity" symposium: Meeting report. Experimental Gerontology. PMID 29287773 DOI: 10.1016/J.Exger.2017.12.004 |
0.379 |
|
| 2017 |
Frasca D, Blomberg BB, Paganelli R. Aging, Obesity, and Inflammatory Age-Related Diseases. Frontiers in Immunology. 8: 1745. PMID 29270179 DOI: 10.3389/Fimmu.2017.01745 |
0.348 |
|
| 2017 |
Frasca D, Blomberg BB. Adipose Tissue Inflammation Induces B Cell Inflammation and Decreases B Cell Function in Aging. Frontiers in Immunology. 8: 1003. PMID 28894445 DOI: 10.3389/Fimmu.2017.01003 |
0.541 |
|
| 2017 |
Frasca D. Senescent B cells in aging and age-related diseases: Their role in the regulation of antibody responses. Experimental Gerontology. PMID 28687479 DOI: 10.1016/J.Exger.2017.07.002 |
0.537 |
|
| 2017 |
Frasca D, Diaz A, Romero M, D'Eramo F, Blomberg BB. Aging effects on T-bet expression in human B cell subsets. Cellular Immunology. PMID 28457482 DOI: 10.1016/J.Cellimm.2017.04.007 |
0.5 |
|
| 2017 |
Diaz A, Romero M, Vazquez T, Lechner S, Blomberg BB, Frasca D. Metformin improves in vivo and in vitro B cell function in individuals with obesity and Type-2 Diabetes. Vaccine. PMID 28392139 DOI: 10.1016/J.Vaccine.2017.03.078 |
0.449 |
|
| 2017 |
Frasca D, Diaz A, Romero M, Vazquez T, Blomberg BB. Obesity induces pro-inflammatory B cells and impairs B cell function in old mice. Mechanisms of Ageing and Development. PMID 28111127 DOI: 10.1016/J.Mad.2017.01.004 |
0.547 |
|
| 2017 |
Pala O, Diaz A, Aubourg B, Greidinger E, Blomberg B, Frasca D. SAT0018 Effects of ANTI-TNF alpha therapy on B cells in rheumatoid arthritis (RA) patients Annals of the Rheumatic Diseases. 76: 775-775. DOI: 10.1136/Annrheumdis-2017-Eular.4331 |
0.491 |
|
| 2017 |
Frasca D, Romero M, Diaz A, Blomberg B. B CELL SENESCENCE IMPAIRS THE INFLUENZA VACCINE RESPONSE Innovation in Aging. 1: 1280-1281. DOI: 10.1093/Geroni/Igx004.4674 |
0.403 |
|
| 2016 |
Frasca D, Blomberg BB. B Cell-Specific Biomarkers for Optimal Antibody Responses to Influenza Vaccination and Molecular Pathways That Reduce B Cell Function with Aging. Critical Reviews in Immunology. 36: 523-537. PMID 28845758 DOI: 10.1615/Critrevimmunol.2017020113 |
0.495 |
|
| 2016 |
Frasca D, Diaz A, Romero M, Blomberg BB. Human peripheral late/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways. Experimental Gerontology. PMID 27931848 DOI: 10.1016/J.Exger.2016.12.001 |
0.494 |
|
| 2016 |
Pinti M, Appay V, Campisi J, Frasca D, Fülöp T, Sauce D, Larbi A, Weinberger B, Cossarizza A. Aging of the immune system - focus on inflammation and vaccination. European Journal of Immunology. PMID 27595500 DOI: 10.1002/Eji.201546178 |
0.458 |
|
| 2016 |
Frasca D, Diaz A, Romero M, Blomberg BB. Aging and obesity similarly impair antibody responses. Clinical and Experimental Immunology. PMID 27314456 DOI: 10.1111/Cei.12824 |
0.391 |
|
| 2016 |
Frasca D, Diaz A, Romero M, Blomberg BB. The generation of memory B cells is maintained, but the antibody response is not, in the elderly after repeated influenza immunizations. Vaccine. PMID 27108193 DOI: 10.1016/J.Vaccine.2016.04.023 |
0.452 |
|
| 2016 |
Frasca D, Ferracci F, Diaz A, Romero M, Lechner S, Blomberg BB. Obesity decreases B cell responses in young and elderly individuals. Obesity (Silver Spring, Md.). PMID 26857091 DOI: 10.1002/Oby.21383 |
0.348 |
|
| 2016 |
Frasca D, Blomberg BB. Inflammaging decreases adaptive and innate immune responses in mice and humans. Biogerontology. 17: 7-19. PMID 25921609 DOI: 10.1007/S10522-015-9578-8 |
0.428 |
|
| 2015 |
Nakaya HI, Hagan T, Duraisingham SS, Lee EK, Kwissa M, Rouphael N, Frasca D, Gersten M, Mehta AK, Gaujoux R, Li GM, Gupta S, Ahmed R, Mulligan MJ, Shen-Orr S, et al. Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures. Immunity. 43: 1186-98. PMID 26682988 DOI: 10.1016/J.Immuni.2015.11.012 |
0.313 |
|
| 2015 |
Frasca D, Blomberg BB. Aging, cytomegalovirus (CMV) and influenza vaccine responses. Human Vaccines & Immunotherapeutics. 0. PMID 26588038 DOI: 10.1080/21645515.2015.1105413 |
0.325 |
|
| 2015 |
McElhaney JE, Garneau H, Camous X, Dupuis G, Pawelec G, Baehl S, Tessier D, Frost EH, Frasca D, Larbi A, Fulop T. Predictors of the antibody response to influenza vaccination in older adults with type 2 diabetes. Bmj Open Diabetes Research & Care. 3: e000140. PMID 26504526 DOI: 10.1136/Bmjdrc-2015-000140 |
0.321 |
|
| 2015 |
Frasca D, Diaz A, Blomberg BB. Activation-Induced Cytidine Deaminase and Switched Memory B Cells as Predictors of Effective In Vivo Responses to the Influenza Vaccine. Methods in Molecular Biology (Clifton, N.J.). 1343: 107-14. PMID 26420712 DOI: 10.1007/978-1-4939-2963-4_9 |
0.415 |
|
| 2015 |
Frasca D, Diaz A, Romero M, Ferracci F, Blomberg BB. MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals. Journal of Immunology (Baltimore, Md. : 1950). 195: 2134-40. PMID 26223652 DOI: 10.4049/Jimmunol.1500520 |
0.454 |
|
| 2015 |
Ratliff M, Alter S, McAvoy K, Frasca D, Wright JA, Zinkel SS, Khan WN, Blomberg BB, Riley RL. In aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells. Aging Cell. 14: 382-90. PMID 25727904 DOI: 10.1111/Acel.12302 |
0.746 |
|
| 2015 |
Frasca D, Diaz A, Romero M, Landin AM, Blomberg BB. Cytomegalovirus (CMV) seropositivity decreases B cell responses to the influenza vaccine. Vaccine. 33: 1433-9. PMID 25659271 DOI: 10.1016/J.Vaccine.2015.01.071 |
0.43 |
|
| 2014 |
Cossarizza A, Frasca D. Aging and longevity: an immunological perspective. Immunology Letters. 162: 279-80. PMID 25200272 DOI: 10.1016/J.Imlet.2014.09.003 |
0.37 |
|
| 2014 |
Frasca D, Blomberg BB. B cell function and influenza vaccine responses in healthy aging and disease. Current Opinion in Immunology. 29: 112-8. PMID 24934648 DOI: 10.1016/J.Coi.2014.05.008 |
0.4 |
|
| 2014 |
Sansoni P, Vescovini R, Fagnoni FF, Akbar A, Arens R, Chiu YL, CiÄin-Å ain L, Dechanet-Merville J, Derhovanessian E, Ferrando-Martinez S, Franceschi C, Frasca D, Fulöp T, Furman D, Gkrania-Klotsas E, et al. New advances in CMV and immunosenescence. Experimental Gerontology. 55: 54-62. PMID 24703889 DOI: 10.1016/J.Exger.2014.03.020 |
0.396 |
|
| 2014 |
Faragher R, Frasca D, Remarque E, Pawelec G. Better immunity in later life: a position paper. Age (Dordrecht, Netherlands). 36: 9619. PMID 24532368 DOI: 10.1007/S11357-014-9619-2 |
0.34 |
|
| 2014 |
Frasca D, Diaz A, Romero M, Landin AM, Blomberg BB. High TNF-α levels in resting B cells negatively correlate with their response. Experimental Gerontology. 54: 116-22. PMID 24440385 DOI: 10.1016/J.Exger.2014.01.004 |
0.516 |
|
| 2013 |
Parmigiani A, Alcaide ML, Freguja R, Pallikkuth S, Frasca D, Fischl MA, Pahwa S. Impaired antibody response to influenza vaccine in HIV-infected and uninfected aging women is associated with immune activation and inflammation. Plos One. 8: e79816. PMID 24236161 DOI: 10.1371/Journal.Pone.0079816 |
0.349 |
|
| 2013 |
Blomberg BB, Frasca D. Age effects on mouse and human B cells. Immunologic Research. 57: 354-60. PMID 24203437 DOI: 10.1007/S12026-013-8440-9 |
0.599 |
|
| 2013 |
Scholz JL, Diaz A, Riley RL, Cancro MP, Frasca D. A comparative review of aging and B cell function in mice and humans. Current Opinion in Immunology. 25: 504-10. PMID 23932400 DOI: 10.1016/J.Coi.2013.07.006 |
0.724 |
|
| 2013 |
Wistuba-Hamprecht K, Frasca D, Blomberg B, Pawelec G, Derhovanessian E. Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus. Immunity & Ageing : I & A. 10: 26. PMID 23822093 DOI: 10.1186/1742-4933-10-26 |
0.37 |
|
| 2013 |
Frasca D, Diaz A, Romero M, Mendez NV, Landin AM, Ryan JG, Blomberg BB. Young and elderly patients with type 2 diabetes have optimal B cell responses to the seasonal influenza vaccine. Vaccine. 31: 3603-10. PMID 23711934 DOI: 10.1016/J.Vaccine.2013.05.003 |
0.501 |
|
| 2013 |
Frasca D, Diaz A, Romero M, Mendez NV, Landin AM, Blomberg BB. Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine season. Immunity & Ageing : I & A. 10: 14. PMID 23607926 DOI: 10.1186/1742-4933-10-14 |
0.341 |
|
| 2013 |
Ratliff M, Alter S, Frasca D, Blomberg BB, Riley RL. In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors. Aging Cell. 12: 303-11. PMID 23410004 DOI: 10.1111/Acel.12055 |
0.749 |
|
| 2013 |
Frasca D, Andrisani G, Diaz A, Felice C, Guidi L, Blomberg BB. AID in aging and autoimmune diseases. Autoimmunity. 46: 168-75. PMID 23190037 DOI: 10.3109/08916934.2012.750300 |
0.407 |
|
| 2012 |
Solana R, Tarazona R, Aiello AE, Akbar AN, Appay V, Beswick M, Bosch JA, Campos C, Cantisán S, Cicin-Sain L, Derhovanessian E, Ferrando-Martínez S, Frasca D, Fulöp T, Govind S, et al. CMV and Immunosenescence: from basics to clinics. Immunity & Ageing : I & A. 9: 23. PMID 23114110 DOI: 10.1186/1742-4933-9-23 |
0.356 |
|
| 2012 |
Khurana S, Frasca D, Blomberg B, Golding H. AID activity in B cells strongly correlates with polyclonal antibody affinity maturation in-vivo following pandemic 2009-H1N1 vaccination in humans. Plos Pathogens. 8: e1002920. PMID 23028320 DOI: 10.1371/Journal.Ppat.1002920 |
0.386 |
|
| 2012 |
Frasca D, Diaz A, Romero M, Phillips M, Mendez NV, Landin AM, Blomberg BB. Unique biomarkers for B-cell function predict the serum response to pandemic H1N1 influenza vaccine. International Immunology. 24: 175-82. PMID 22281510 DOI: 10.1093/Intimm/Dxr123 |
0.426 |
|
| 2012 |
Frasca D, Romero M, Diaz A, Alter-Wolf S, Ratliff M, Landin AM, Riley RL, Blomberg BB. A molecular mechanism for TNF-α-mediated downregulation of B cell responses. Journal of Immunology (Baltimore, Md. : 1950). 188: 279-86. PMID 22116831 DOI: 10.4049/Jimmunol.1003964 |
0.727 |
|
| 2011 |
Blomberg BB, Frasca D. Comments on the evaluation of lymphocyte levels in a random sample of 218 elderly individuals from São Paulo city. Revista Brasileira De Hematologia E Hemoterapia. 33: 333-4. PMID 23049334 DOI: 10.5581/1516-8484.20110093 |
0.381 |
|
| 2011 |
Frasca D, Blomberg BB. Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissues. Aging and Disease. 2: 361-73. PMID 22396888 |
0.543 |
|
| 2011 |
Daftarian P, Kaifer AE, Li W, Blomberg BB, Frasca D, Roth F, Chowdhury R, Berg EA, Fishman JB, Al Sayegh HA, Blackwelder P, Inverardi L, Perez VL, Lemmon V, Serafini P. Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells. Cancer Research. 71: 7452-62. PMID 21987727 DOI: 10.1158/0008-5472.Can-11-1766 |
0.326 |
|
| 2011 |
Blomberg BB, Frasca D. Quantity, not quality, of antibody response decreased in the elderly. The Journal of Clinical Investigation. 121: 2981-3. PMID 21785210 DOI: 10.1172/Jci58406 |
0.304 |
|
| 2011 |
Frasca D, Blomberg BB. Aging affects human B cell responses. Journal of Clinical Immunology. 31: 430-5. PMID 21318330 DOI: 10.1007/S10875-010-9501-7 |
0.539 |
|
| 2011 |
Landin AM, Frasca D, Harrison P, Scallan M, Riley RL, Blomberg BB. E47 retroviral rescue of intrinsic B-cell defects in senescent mice. Aging Cell. 10: 327-37. PMID 21241451 DOI: 10.1111/J.1474-9726.2011.00673.X |
0.762 |
|
| 2011 |
Frasca D, Diaz A, Romero M, Landin AM, Blomberg BB. Age effects on B cells and humoral immunity in humans. Ageing Research Reviews. 10: 330-5. PMID 20728581 DOI: 10.1016/J.Arr.2010.08.004 |
0.586 |
|
| 2010 |
Frasca D, Diaz A, Romero M, Landin AM, Phillips M, Lechner SC, Ryan JG, Blomberg BB. Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans. Vaccine. 28: 8077-84. PMID 20974306 DOI: 10.1016/J.Vaccine.2010.10.023 |
0.441 |
|
| 2010 |
Frasca D, Romero M, Landin AM, Diaz A, Riley RL, Blomberg BB. Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability. Mechanisms of Ageing and Development. 131: 306-14. PMID 20219523 DOI: 10.1016/J.Mad.2010.02.002 |
0.717 |
|
| 2010 |
Tsukamoto H, Huston GE, Dibble J, Duso DK, Swain SL, Lefebvre JS, Maue AM, Petell AH, Lanthier PA, Tighe M, Eaton SM, Woodland DL, Haynes L, Boyd RL, Fletcher AL, ... ... Frasca D, et al. Aging and immunity (WS-105) Chairpersons: Toshikazu Yoshikawa, Janko Nikolich-Žugich International Immunology. 22. DOI: 10.1093/Intimm/Dxq421 |
0.387 |
|
| 2009 |
Frasca D, Blomberg BB. Effects of aging on B cell function. Current Opinion in Immunology. 21: 425-30. PMID 19608393 DOI: 10.1016/J.Coi.2009.06.001 |
0.586 |
|
| 2009 |
Cancro MP, Hao Y, Scholz JL, Riley RL, Frasca D, Dunn-Walters DK, Blomberg BB. B cells and aging: molecules and mechanisms. Trends in Immunology. 30: 313-8. PMID 19540810 DOI: 10.1016/J.It.2009.04.005 |
0.731 |
|
| 2009 |
Landin AM, Frasca D, Zaias J, Van der Put E, Riley RL, Altman NH, Blomberg BB. Effects of fenbendazole on the murine humoral immune system. Journal of the American Association For Laboratory Animal Science : Jaalas. 48: 251-7. PMID 19476712 |
0.667 |
|
| 2008 |
Frasca D, Landin AM, Lechner SC, Ryan JG, Schwartz R, Riley RL, Blomberg BB. Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 5283-90. PMID 18390709 DOI: 10.4049/Jimmunol.180.8.5283 |
0.764 |
|
| 2008 |
Frasca D, Landin AM, Riley RL, Blomberg BB. Mechanisms for decreased function of B cells in aged mice and humans. Journal of Immunology (Baltimore, Md. : 1950). 180: 2741-6. PMID 18292491 DOI: 10.4049/Jimmunol.180.5.2741 |
0.749 |
|
| 2007 |
Frasca D, Landin AM, Alvarez JP, Blackshear PJ, Riley RL, Blomberg BB. Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA. Journal of Immunology (Baltimore, Md. : 1950). 179: 918-27. PMID 17617583 DOI: 10.4049/Jimmunol.179.2.918 |
0.72 |
|
| 2007 |
Frasca D, Riley RL, Blomberg BB. Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF. Experimental Gerontology. 42: 192-203. PMID 17067770 DOI: 10.1016/J.Exger.2006.09.003 |
0.692 |
|
| 2005 |
Frasca D, Van der Put E, Landin AM, Gong D, Riley RL, Blomberg BB. RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 6633-44. PMID 16272318 DOI: 10.4049/Jimmunol.175.10.6633 |
0.727 |
|
| 2005 |
Frasca D, Riley RL, Blomberg BB. Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans. Seminars in Immunology. 17: 378-84. PMID 15996480 DOI: 10.1016/J.Smim.2005.05.005 |
0.752 |
|
| 2005 |
Riley RL, Van der Put E, King AM, Frasca D, Blomberg BB. Deficient B lymphopoiesis in murine senescence: potential roles for dysregulation of E2A, Pax-5, and STAT5. Seminars in Immunology. 17: 330-6. PMID 15967678 DOI: 10.1016/J.Smim.2005.05.011 |
0.732 |
|
| 2005 |
Riley RL, Blomberg BB, Frasca D. B cells, E2A, and aging. Immunological Reviews. 205: 30-47. PMID 15882343 DOI: 10.1111/J.0105-2896.2005.00268.X |
0.758 |
|
| 2004 |
Frasca D, Riley RL, Blomberg BB. Effect of age on the immunoglobulin class switch. Critical Reviews in Immunology. 24: 297-320. PMID 15663361 DOI: 10.1615/Critrevimmunol.V24.I5.10 |
0.77 |
|
| 2004 |
Van der Put E, Frasca D, King AM, Blomberg BB, Riley RL. Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover. Journal of Immunology (Baltimore, Md. : 1950). 173: 818-27. PMID 15240668 DOI: 10.4049/Jimmunol.173.2.818 |
0.731 |
|
| 2004 |
Doria G, Barattini P, Scarpaci S, Puel A, Guidi L, Frasca D. Role of immune responsiveness and DNA repair capacity genes in ageing. Ageing Research Reviews. 3: 143-51. PMID 15177051 DOI: 10.1016/J.Arr.2003.04.001 |
0.38 |
|
| 2004 |
Frasca D, Van Der Put E, Riley RL, Blomberg BB. Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells. Experimental Gerontology. 39: 481-9. PMID 15050281 DOI: 10.1016/J.Exger.2003.09.027 |
0.74 |
|
| 2004 |
Frasca D, Nguyen D, Riley RL, Blomberg BB. Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells. Mechanisms of Ageing and Development. 125: 111-2. PMID 15037012 DOI: 10.1016/J.Mad.2003.11.004 |
0.726 |
|
| 2004 |
Frasca D, Van der Put E, Riley RL, Blomberg BB. Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase. Journal of Immunology (Baltimore, Md. : 1950). 172: 2155-62. PMID 14764681 DOI: 10.4049/Jimmunol.172.4.2155 |
0.681 |
|
| 2003 |
Scarpaci S, Frasca D, Barattini P, Guidi L, Doria G. DNA damage recognition and repair capacities in human naïve and memory T cells from peripheral blood of young and elderly subjects. Mechanisms of Ageing and Development. 124: 517-24. PMID 12714261 DOI: 10.1016/S0047-6374(03)00030-7 |
0.333 |
|
| 2003 |
Frasca D, Nguyen D, Riley RL, Blomberg BB. Effects of aging on proliferation and E47 transcription factor activity induced by different stimuli in murine splenic B cells. Mechanisms of Ageing and Development. 124: 361-9. PMID 12714241 DOI: 10.1016/S0047-6374(03)00009-5 |
0.739 |
|
| 2003 |
Frasca D, Nguyen D, Van der Put E, Riley RL, Blomberg BB. The age-related decrease in E47 DNA-binding does not depend on increased Id inhibitory proteins in bone marrow-derived B cell precursors. Frontiers in Bioscience : a Journal and Virtual Library. 8: a110-6. PMID 12700059 DOI: 10.2741/1059 |
0.745 |
|
| 2003 |
Frasca D, Nguyen D, Riley RL, Blomberg BB. Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. Journal of Immunology (Baltimore, Md. : 1950). 170: 719-26. PMID 12517933 DOI: 10.4049/Jimmunol.170.2.719 |
0.735 |
|
| 2002 |
Pawelec G, Barnett Y, Forsey R, Frasca D, Globerson A, McLeod J, Caruso C, Franceschi C, Fülöp T, Gupta S, Mariani E, Mocchegiani E, Solana R. T cells and aging, January 2002 update. Frontiers in Bioscience : a Journal and Virtual Library. 7: d1056-183. PMID 11991846 DOI: 10.2741/A831 |
0.516 |
|
| 2002 |
Frasca D, Scarpaci S, Barattini P, Bartoloni C, Guidi L, Costanzo M, Doria G. The DNA repair protein ku is involved in gp130-mediated signal transduction events in PBMC from young but not from elderly subjects. Experimental Gerontology. 37: 321-8. PMID 11772519 DOI: 10.1016/S0531-5565(01)00199-1 |
0.348 |
|
| 2002 |
Frasca D, Guidi L, Doria G. Role of DNA-dependent protein kinase (DNA-PK), a protein with multiple intracellular functions, in cells of the ageing immune system Advances in Cell Aging and Gerontology. 13: 217-230. DOI: 10.1016/S1566-3124(02)13012-4 |
0.357 |
|
| 2001 |
Doria G, Frasca D. Age-related changes of DNA damage recognition and repair capacity in cells of the immune system. Mechanisms of Ageing and Development. 122: 985-98. PMID 11348662 DOI: 10.1016/S0047-6374(01)00251-2 |
0.384 |
|
| 2001 |
Frasca D, Barattini P, Tocchi G, Guidi F, Scarpaci S, Guidi L, Bartoloni C, Errani A, Costanzo M, Doria G. Modulation of X-ray-induced damage recognition and repair in ageing human peripheral blood mononuclear cells by an interleukin-6-type cytokine. Mechanisms of Ageing and Development. 121: 5-19. PMID 11164456 DOI: 10.1016/S0047-6374(00)00193-7 |
0.318 |
|
| 2000 |
Frasca D, Guidi F, Arbitrio M, Pioli C, Poccia F, Cicconi R, Doria G. Hematopoietic reconstitution after lethal irradiation and bone marrow transplantation: effects of different hematopoietic cytokines on the recovery of thymus, spleen and blood cells. Bone Marrow Transplantation. 25: 427-33. PMID 10723587 DOI: 10.1038/Sj.Bmt.1702169 |
0.339 |
|
| 2000 |
Doria G, Frasca D. Genetic factors in immunity and aging. Vaccine. 18: 1591-5. PMID 10689133 DOI: 10.1016/S0264-410X(99)00491-0 |
0.411 |
|
| 1999 |
Frasca D, Barattini P, Tirindelli D, Guidi L, Bartoloni C, Errani A, Costanzo M, Tricerri A, Pierelli L, Doria G. Effect of age on DNA binding of the ku protein in irradiated human peripheral blood mononuclear cells (PBMC). Experimental Gerontology. 34: 645-58. PMID 10530790 DOI: 10.1016/S0531-5565(99)00026-1 |
0.37 |
|
| 1999 |
Frasca D, Guidi F, Barattini P, Doria G. Haemopoietic reconstitution after sublethal irradiation: comparison of the effects of different haemopoietic cytokines on murine lymphocytes and bone marrow cells. British Journal of Haematology. 106: 317-24. PMID 10460587 DOI: 10.1046/J.1365-2141.1999.01558.X |
0.343 |
|
| 1999 |
Pioli C, Gatta L, Frasca D, Doria G. Cytotoxic T lymphocyte antigen 4 (CTLA-4) inhibits CD28-induced IkappaBalpha degradation and RelA activation. European Journal of Immunology. 29: 856-63. PMID 10092088 DOI: 10.1002/(Sici)1521-4141(199903)29:03<856::Aid-Immu856>3.0.Co;2-P |
0.311 |
|
| 1999 |
Pucci S, Doria G, Barile S, Pioli C, Frasca D. Inhibition of IL-2 production by Nil-2-a in murine T cells. International Immunology. 10: 1435-40. PMID 9796909 DOI: 10.1093/Intimm/10.10.1435 |
0.418 |
|
| 1998 |
Pioli C, Pucci S, Barile S, Frasca D, Doria G. Role of mRNA stability in the different patterns of cytokine production by CD4+ cells from young and old mice. Immunology. 94: 380-7. PMID 9767421 DOI: 10.1046/J.1365-2567.1998.00523.X |
0.361 |
|
| 1998 |
Guidi L, Antico L, Bartoloni C, Costanzo M, Errani A, Tricerri A, Vangeli M, Doria G, Gatta L, Goso C, Mancino L, Frasca D. Changes in the amount and level of phosphorylation of p56(lck) in PBL from aging humans Mechanisms of Ageing and Development. 102: 177-186. PMID 9720650 DOI: 10.1016/S0047-6374(97)00144-9 |
0.385 |
|
| 1998 |
Guidi L, Tricerri A, Frasca D, Vangeli M, Errani AR, Bartoloni C. Psychoneuroimmunology and aging. Gerontology. 44: 247-61. PMID 9693255 DOI: 10.1159/000022021 |
0.354 |
|
| 1998 |
Poccia F, Cicconi R, Frasca D, Mancini C, Colizzi V, Doria G. Age-related propensity to peripheral expansion of Vgamma3+ gammadelta+ T lymphocytes after irradiation and bone marrow transplantation. International Immunology. 10: 547-51. PMID 9620611 DOI: 10.1093/Intimm/10.4.547 |
0.407 |
|
| 1998 |
Frasca D, Barattini P, Goso C, Pucci S, Rizzo G, Bartoloni C, Costanzo M, Errani A, Guidi L, Antico L, Tricerri A, Doria G. Cell proliferation and ku protein expression in ageing humans. Mechanisms of Ageing and Development. 100: 197-208. PMID 9541140 DOI: 10.1016/S0047-6374(97)00137-1 |
0.408 |
|
| 1998 |
Doria G, Frasca D. Genes, immunity, and senescence: looking for a link. Immunological Reviews. 160: 159-70. PMID 9476674 DOI: 10.1111/J.1600-065X.1997.Tb01036.X |
0.507 |
|
| 1998 |
Frasca D, Doria G. Recombinant cytokines as an approach to immune reconstitution in aging. Developmental and Comparative Immunology. 21: 525-30. PMID 9463785 DOI: 10.1016/S0145-305X(97)00032-3 |
0.422 |
|
| 1998 |
Frasca D, Barattini P, Goso C, Pucci S, Rizzo G, Bartoloni C, Costanzo M, Errani A, Guidi L, Antico L, Tricerri A, Doria G. Abstract to 'Cell proliferation and ku protein expression in ageing humans' [Mech. Ageing Dev., 100 (1998) 197-208] Mechanisms of Ageing and Development. 102: 307-308. DOI: 10.1016/S0047-6374(98)00055-4 |
0.418 |
|
| 1997 |
Doria G, Mancini C, Utsuyama M, Frasca D, Hirokawa K. Aging of the recipients but not of the bone marrow donors enhances autoimmunity in syngeneic radiation chimeras. Mechanisms of Ageing and Development. 95: 131-42. PMID 9152966 DOI: 10.1016/S0047-6374(97)01871-X |
0.464 |
|
| 1997 |
Frasca D, Pucci S, Goso C, Barattini P, Barile S, Pioli C, Doria G. Regulation of cytokine production in aging: use of recombinant cytokines to upregulate mitogen-stimulated spleen cells. Mechanisms of Ageing and Development. 93: 157-69. PMID 9089580 DOI: 10.1016/S0047-6374(96)01825-8 |
0.359 |
|
| 1997 |
Frasca D, Pioli C, Guidi F, Pucci S, Arbitrio M, Leter G, Doria G. IL-11 synergizes with IL-3 in promoting the recovery of the immune system after irradiation. International Immunology. 8: 1651-7. PMID 8943559 DOI: 10.1093/Intimm/8.11.1651 |
0.434 |
|
| 1997 |
Frasca D, Pucci S, Barattini P, Goso C, Pioli C, Tirindelli Danesi D, Doria G. Possible involvement of ku protein in hematopoietic cytokine-driven recovery of the immune system after irradiation Immunology Letters. 56: 394. DOI: 10.1016/S0165-2478(97)86592-3 |
0.323 |
|
| 1997 |
Pucci S, Barile S, Pioli C, Doria G, Frasca D. Evidence for the existence of age-related differences in the level of a nuclear factor inhibiting IL-2 gene transcription Immunology Letters. 56: 77-78. DOI: 10.1016/S0165-2478(97)85300-X |
0.329 |
|
| 1997 |
Pioli C, Pucci S, Barile S, Barattini P, Goso C, Frasca D, Doria G. Cytokine production in CD4 cells from aging mice as induced by CD28 costimulation Immunology Letters. 56: 52. DOI: 10.1016/S0165-2478(97)85195-4 |
0.364 |
|
| 1996 |
Brunelli R, Frasca D, Perrone G, Pioli C, Fattorossi A, Zichella L, Doria G. Hormone replacement therapy affects various immune cell subsets and natural cytotoxicity. Gynecologic and Obstetric Investigation. 41: 128-31. PMID 8838974 DOI: 10.1159/000292057 |
0.316 |
|
| 1995 |
Frasca D, Pioli C, Leter G, Doria G. Use of cytokines to enhance recovery of the immune system after irradiation Pharmacological Research. 31: 300. DOI: 10.1016/1043-6618(95)87459-3 |
0.305 |
|
| 1994 |
Doria G, Frasca D. Ageing and genetic control of immune responsiveness. Immunology Letters. 40: 231-3. PMID 7959892 DOI: 10.1016/0165-2478(94)00061-1 |
0.402 |
|
| 1994 |
Doria G, Frasca D. Regulation of cytokine production in aging mice. Annals of the New York Academy of Sciences. 741: 299-304. PMID 7825818 DOI: 10.1111/J.1749-6632.1994.Tb23113.X |
0.402 |
|
| 1994 |
Frasca D, Leter G, Doria G. Murine recombinant interleukin-3 induces recovery of T and B cells in irradiated mice Blood. 83: 1563-1568. DOI: 10.1182/Blood.V83.6.1563.Bloodjournal8361563 |
0.412 |
|
| 1993 |
Doria G, Leter G, Mancini C, Frasca D. Effect of recombinant IL-3 on lymphocyte populations in irradiated mice. Stem Cells (Dayton, Ohio). 93-7. PMID 8401261 DOI: 10.1002/Stem.5530110816 |
0.431 |
|
| 1993 |
Brunelli R, Frasca D, Spanò M, Zichella L, Doria G. Gonadectomy in old mice induces thymus regeneration but does not recover mitotic responsiveness. Annals of the New York Academy of Sciences. 673: 252-5. PMID 1485722 DOI: 10.1111/J.1749-6632.1992.Tb27460.X |
0.35 |
|
| 1993 |
Doria G, Frasca D, Covelli V. An immunological approach to aging. Annals of the New York Academy of Sciences. 673: 226-30. PMID 1485718 DOI: 10.1111/J.1749-6632.1992.Tb27457.X |
0.339 |
|
| 1992 |
Doria G, Baschieri S, Goso C, Brunelli R, Zichella L, Spano M, Fattorossi A, D'Amelio R, Frasca D. Hormonal regulation of T cell differentiation in aging mice. Annals of the New York Academy of Sciences. 650: 121-4. PMID 1534973 DOI: 10.1111/J.1749-6632.1992.Tb49107.X |
0.426 |
|
| 1992 |
Caroleo MC, Frasca D, Nisticó G, Doria G. Melatonin as immunomodulator in immunodeficient mice. Immunopharmacology. 23: 81-9. PMID 1534792 DOI: 10.1016/0162-3109(92)90031-7 |
0.42 |
|
| 1992 |
Goso C, Frasca D, Doria G. Effect of synthetic thymic humoral factor (THF-gamma 2) on T cell activities in immunodeficient ageing mice. Clinical and Experimental Immunology. 87: 346-51. PMID 1531947 DOI: 10.1111/J.1365-2249.1992.Tb03000.X |
0.422 |
|
| 1991 |
Guidi L, Bartoloni C, Frasca D, Antico L, Pili R, Cursi F, Tempesta E, Rumi C, Menini E, Carbonin P, Doria G, Gambassi G. Impairment of lymphocyte activities in depressed aged subjects Mechanisms of Ageing and Development. 60: 13-24. PMID 1745061 DOI: 10.1016/0047-6374(91)90105-9 |
0.358 |
|
| 1991 |
Bartoloni C, Guidi L, Frasca D, Antico L, Pili R, Cursi F, Di Giovanni A, Rumi C, Menini E, Carbonin P, Doria G, Gambassi G. Immune parameters in a populatio of institutionalized elderly subjects: influence of depressive disorders and endocrinological correlations Mechanisms of Ageing and Development. 60: 1-12. PMID 1745060 DOI: 10.1016/0047-6374(91)90104-8 |
0.369 |
|
| 1991 |
Goso C, Frasca D, Doria G. Effects of synthetic thymic hormones on T cell activities in old mice International Journal of Immunopharmacology. 13: 800. DOI: 10.1016/0192-0561(91)90361-A |
0.374 |
|
| 1991 |
Frasca D, Zingoni A, Leter G, Spano M, Doria G. Effect of IL-3 on T and B cells in irradiated mice International Journal of Immunopharmacology. 13: 754. DOI: 10.1016/0192-0561(91)90278-F |
0.439 |
|
| 1989 |
Doria G, Mancini C, Frasca D. Age-related changes within a suppressor T cell circuit. Cellular Immunology. 122: 20-32. PMID 2526688 DOI: 10.1016/0008-8749(89)90145-7 |
0.507 |
|
| 1988 |
Barcellini W, Meroni PL, Borghi MO, Frasca D, Perego R, Doria G, Zanussi C. In vivo immunopotentiating activity of thymopentin in aging humans: modulation of IL-2 receptor expression. Clinical Immunology and Immunopathology. 48: 140-9. PMID 3134150 DOI: 10.1016/0090-1229(88)90078-5 |
0.379 |
|
| 1988 |
Barcellini W, Borghi MO, Sguotti C, Palmieri R, Frasca D, Meroni PL, Doria G, Zanussi C. Heterogeneity of immune responsiveness in healthy elderly subjects. Clinical Immunology and Immunopathology. 47: 142-51. PMID 3127098 DOI: 10.1016/0090-1229(88)90067-0 |
0.446 |
|
| 1988 |
Doria G, Adorini L, Sabbadini E, Mancini C, Frasca D. Immunoregulation in aging. Annals of the New York Academy of Sciences. 521: 182-8. PMID 2897816 DOI: 10.1111/J.1749-6632.1988.Tb35277.X |
0.358 |
|
| 1987 |
Meroni PL, Barcellini W, Frasca D, Sguotti C, Borghi MO, De Bartolo G, Doria G, Zanussi C. In vivo immunopotentiating activity of thymopentin in aging humans: increase of IL-2 production. Clinical Immunology and Immunopathology. 42: 151-9. PMID 3542319 DOI: 10.1016/0090-1229(87)90002-X |
0.396 |
|
| 1987 |
Doria G, Adorini L, Mancini C, Frasca D. T cell reconstitution by thymic hormones in aging MemóRias Do Instituto Oswaldo Cruz. 82: 9-13. DOI: 10.1590/S0074-02761987000600004 |
0.383 |
|
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