Ioannis Melas - Publications

Affiliations: 
2009-2014 Mechanical Engineering National Technical University of Athens, Greece 

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Melas IN, Sakellaropoulos T, Hur J, Messinis D, Guo EY, Alexopoulos LG, Bai JPF. A Computational Platform and Guide for Acceleration of Novel Medicines and Personalized Medicine. Methods in Molecular Biology (Clifton, N.J.). 1939: 181-198. PMID 30848462 DOI: 10.1007/978-1-4939-9089-4_10  0.72
2018 Messinis DE, Melas IN, Hur J, Varshney N, Alexopoulos LG, Bai JPF. Translational systems pharmacology-based predictive assessment of drug-induced cardiomyopathy. Cpt: Pharmacometrics & Systems Pharmacology. PMID 29341478 DOI: 10.1002/psp4.12272  0.72
2017 Bai JPF, Melas IN, Hur J, Guo E. Advances in omics for informed pharmaceutical research and development in the era of systems medicine. Expert Opinion On Drug Discovery. 1-4. PMID 29073782 DOI: 10.1080/17460441.2018.1394839  0.36
2016 Sakellaropoulos T, Hur J, Melas IN, Guo EY, Alexopoulos L, Bohlooly M, Bai JP. Computational Approaches to Accelerating Novel Medicine and Better Patient Care from Bedside to Benchtop. Advances in Protein Chemistry and Structural Biology. 102: 147-79. PMID 26827605 DOI: 10.1016/bs.apcsb.2015.09.005  0.72
2015 Stavrakas V, Melas IN, Sakellaropoulos T, Alexopoulos LG. Network reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theory. Plos One. 10: e0128411. PMID 26020784 DOI: 10.1371/journal.pone.0128411  0.72
2015 Melas IN, Sakellaropoulos T, Iorio F, Alexopoulos LG, Loh WY, Lauffenburger DA, Saez-Rodriguez J, Bai JP. Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 25932872 DOI: 10.1039/c4ib00294f  0.72
2015 Bilal E, Sakellaropoulos T, Melas IN, Messinis DE, Belcastro V, Rhrissorrakrai K, Meyer P, Norel R, Iskandar A, Blaese E, Rice JJ, Peitsch MC, Hoeng J, Stolovitzky G, Alexopoulos LG, et al. A crowd-sourcing approach for the construction of species-specific cell signaling networks. Bioinformatics (Oxford, England). 31: 484-91. PMID 25294919 DOI: 10.1093/bioinformatics/btu659  0.72
2015 Kotelnikova E, Bernardo-Faura M, Silberberg G, Kiani NA, Messinis D, Melas IN, Artigas L, Schwartz E, Mazo I, Masso M, Alexopoulos LG, Mas JM, Olsson T, Tegner J, Martin R, et al. Signaling networks in MS: a systems-based approach to developing new pharmacological therapies. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 138-46. PMID 25112814 DOI: 10.1177/1352458514543339  0.72
2014 Poussin C, Mathis C, Alexopoulos LG, Messinis DE, Dulize RH, Belcastro V, Melas IN, Sakellaropoulos T, Rhrissorrakrai K, Bilal E, Meyer P, Talikka M, Boué S, Norel R, Rice JJ, et al. The species translation challenge-a systems biology perspective on human and rat bronchial epithelial cells. Scientific Data. 1: 140009. PMID 25977767 DOI: 10.1038/sdata.2014.9  0.72
2014 Morris MK, Chi A, Melas IN, Alexopoulos LG. Phosphoproteomics in drug discovery. Drug Discovery Today. 19: 425-32. PMID 24141136 DOI: 10.1016/j.drudis.2013.10.010  0.72
2013 Melas IN, Lauffenburger DA, Alexopoulos LG. Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data. Proceedings / Annual Ieee International Symposium On Bioinformatics and Bioengineering (Bibe). Ieee International Symposium On Bioinformatics and Bioengineering. 2013. PMID 25729777 DOI: 10.1109/BIBE.2013.6701683  0.72
2013 Melas IN, Samaga R, Alexopoulos LG, Klamt S. Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs. Plos Computational Biology. 9: e1003204. PMID 24039561 DOI: 10.1371/journal.pcbi.1003204  0.72
2013 Melas IN, Kretsos K, Alexopoulos LG. Leveraging systems biology approaches in clinical pharmacology. Biopharmaceutics & Drug Disposition. 34: 477-88. PMID 23983165 DOI: 10.1002/bdd.1859  0.72
2013 Morris MK, Melas I, Saez-Rodriguez J. Construction of cell type-specific logic models of signaling networks using CellNOpt. Methods in Molecular Biology (Clifton, N.J.). 930: 179-214. PMID 23086842 DOI: 10.1007/978-1-62703-059-5_8  0.72
2012 Mitsos A, Melas IN, Morris MK, Saez-Rodriguez J, Lauffenburger DA, Alexopoulos LG. Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways. Plos One. 7: e50085. PMID 23226239 DOI: 10.1371/journal.pone.0050085  0.72
2012 Melas IN, Mitsos A, Messinis DE, Weiss TS, Rodriguez JS, Alexopoulos LG. Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data. Molecular Biosystems. 8: 1571-84. PMID 22446821 DOI: 10.1039/c2mb05482e  0.72
2011 Melas IN, Chairakaki AD, Mitsos A, Dailiana Z, Provatidis CG, Alexopoulos LG. Modeling signaling pathways in articular cartilage. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 3712-5. PMID 22255146 DOI: 10.1109/IEMBS.2011.6090630  0.72
2011 Melas IN, Mitsos A, Messinis DE, Weiss TS, Alexopoulos LG. Combined logical and data-driven models for linking signalling pathways to cellular response. Bmc Systems Biology. 5: 107. PMID 21729292 DOI: 10.1186/1752-0509-5-107  0.72
2010 Alexopoulos LG, Melas IN, Chairakaki AD, Saez-Rodriguez J, Mitsos A. Construction of signaling pathways and identification of drug effects on the liver cancer cell HepG2. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2010: 6717-20. PMID 21096084 DOI: 10.1109/IEMBS.2010.5626246  0.72
2009 Mitsos A, Melas IN, Siminelakis P, Chairakaki AD, Saez-Rodriguez J, Alexopoulos LG. Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data. Plos Computational Biology. 5: e1000591. PMID 19997482 DOI: 10.1371/journal.pcbi.1000591  0.72
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