Year |
Citation |
Score |
2023 |
Hong T, Li J, Guo L, Cavalier M, Wang T, Dou Y, DeLaFuente A, Fang S, Guzman A, Wohlan K, Kapadia C, Rosas C, Yang Y, Yin CC, Li S, ... ... Huang Y, et al. TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells. Nature Aging. PMID 37884767 DOI: 10.1038/s43587-023-00505-y |
0.652 |
|
2023 |
Dou Y, Chen R, Liu S, Lee YT, Jing J, Liu X, Ke Y, Wang R, Zhou Y, Huang Y. Optogenetic engineering of STING signaling allows remote immunomodulation to enhance cancer immunotherapy. Nature Communications. 14: 5461. PMID 37673917 DOI: 10.1038/s41467-023-41164-2 |
0.631 |
|
2022 |
Li J, Hong T, Wei Y, Guo L, Lee M, Yang H, Class C, Yang Y, Wang X, He H, Siwko S, You MJ, Zhou Y, Garcia-Manero G, Huang Y. Aberrant DNA hydroxymethylation reshapes transcription factor binding in myeloid neoplasms. Clinical Epigenetics. 14: 81. PMID 35765052 DOI: 10.1186/s13148-022-01297-5 |
0.661 |
|
2022 |
Lan TH, He L, Huang Y, Zhou Y. Optogenetics for transcriptional programming and genetic engineering. Trends in Genetics : Tig. PMID 35738948 DOI: 10.1016/j.tig.2022.05.014 |
0.644 |
|
2022 |
Gu T, Hao D, Woo J, Huang TW, Guo L, Lin X, Guzman AG, Tovy A, Rosas C, Jeong M, Zhou Y, Deneen B, Huang Y, Li W, Goodell MA. The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development. Nature Genetics. PMID 35534561 DOI: 10.1038/s41588-022-01063-6 |
0.654 |
|
2022 |
Wang T, Liu S, Huang Y, Zhou Y. Red-shifted optogenetics comes to the spotlight. Clinical and Translational Medicine. 12: e807. PMID 35389568 DOI: 10.1002/ctm2.807 |
0.576 |
|
2022 |
Tan P, Hong T, Cai X, Li W, Huang Y, He L, Zhou Y. Optical control of protein delivery and partitioning in the nucleolus. Nucleic Acids Research. PMID 35325178 DOI: 10.1093/nar/gkac191 |
0.619 |
|
2022 |
Fang S, Cui D, Hong T, Guo L, Lee YT, Lee M, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Li J, Huang Y. Ten-Eleven Translocation Ablation Impairs Cardiac Differentiation of Mouse Embryonic Stem Cells. Stem Cells (Dayton, Ohio). 40: 260-272. PMID 35296897 DOI: 10.1093/stmcls/sxab017 |
0.654 |
|
2022 |
Xie J, Ma G, Zhou L, He L, Zhang Z, Tan P, Huang Z, Fang S, Wang T, Lee YT, Wen S, Siwko S, Wang L, Liu J, Du Y, ... ... Huang Y, et al. Identification of a STIM1 Splicing Variant that Promotes Glioblastoma Growth. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2103940. PMID 35076181 DOI: 10.1002/advs.202103940 |
0.669 |
|
2022 |
Tan P, He L, Huang Y, Zhou Y. Optophysiology: Illuminating cell physiology with optogenetics. Physiological Reviews. PMID 35072525 DOI: 10.1152/physrev.00021.2021 |
0.637 |
|
2021 |
Nguyen NT, Huang K, Zeng H, Jing J, Wang R, Fang S, Chen J, Liu X, Huang Z, You MJ, Rao A, Huang Y, Han G, Zhou Y. Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nature Nanotechnology. PMID 34697491 DOI: 10.1038/s41565-021-00982-5 |
0.686 |
|
2021 |
Jing Y, Liu Y, Li Q, Ye Y, Diao L, Huang Y, Zhou Y, Green MR, Mills GB, Han L. Expression of chimeric antigen receptor therapy targets detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity. Cancer Cell. PMID 34678153 DOI: 10.1016/j.ccell.2021.09.016 |
0.626 |
|
2021 |
Huang YH, Chen CW, Sundaramurthy V, Slabicki M, Hao D, Watson CJ, Tovy A, Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, ... Huang Y, et al. Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor. Cancer Discovery. PMID 34429321 DOI: 10.1158/2159-8290.CD-21-0560 |
0.632 |
|
2021 |
He L, Tan P, Huang Y, Zhou Y. Design of Smart Antibody Mimetics with Photosensitive Switches. Advanced Biology. 5: e2000541. PMID 34028213 DOI: 10.1002/adbi.202000541 |
0.621 |
|
2021 |
He L, Tan P, Zhu L, Huang K, Nguyen NT, Wang R, Guo L, Li L, Yang Y, Huang Z, Huang Y, Han G, Wang J, Zhou Y. Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering. Nature Chemical Biology. PMID 33958793 DOI: 10.1038/s41589-021-00792-9 |
0.657 |
|
2021 |
Lee M, Li J, Li J, Fang S, Zhang J, Vo ATT, Han W, Zeng H, Isgandarova S, Martinez-Moczygemba M, Zhou Y, Sun D, Huang Y. Tet2 inactivation enhances the anti-tumor activity of tumor-infiltrating lymphocytes. Cancer Research. PMID 33589517 DOI: 10.1158/0008-5472.CAN-20-3213 |
0.625 |
|
2021 |
Wang T, He L, Jing J, Lan TH, Hong T, Wang F, Huang Y, Ma G, Zhou Y. Caffeine-Operated Synthetic Modules for Chemogenetic Control of Protein Activities by Life Style. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 8: 2002148. PMID 33552855 DOI: 10.1002/advs.202002148 |
0.656 |
|
2021 |
He L, Wang L, Zeng H, Tan P, Ma G, Zheng S, Li Y, Sun L, Dou F, Siwko S, Huang Y, Wang Y, Zhou Y. Engineering of a bona fide light-operated calcium channel. Nature Communications. 12: 164. PMID 33431868 DOI: 10.1038/s41467-020-20425-4 |
0.66 |
|
2021 |
Guo L, Lee YT, Zhou Y, Huang Y. Targeting epigenetic regulatory machinery to overcome cancer therapy resistance. Seminars in Cancer Biology. PMID 33421619 DOI: 10.1016/j.semcancer.2020.12.022 |
0.63 |
|
2020 |
Reilly BM, Luger T, Park S, Lio CJ, Gonzalez-Avalos E, Wheeler EC, Lee M, Williamson L, Tanaka T, Diep D, Zhang K, Huang Y, Rao A, Bejar R. 5-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells. Molecular Cancer Research : McR. PMID 33172974 DOI: 10.1158/1541-7786.MCR-20-0453 |
0.477 |
|
2020 |
Li J, Zhao S, Lee M, Yin Y, Li J, Zhou Y, Ballester LY, Esquenazi Y, Dashwood RH, Davies PJA, Parsons DW, Li XN, Huang Y, Sun D. Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma. Science Advances. 6. PMID 33067228 DOI: 10.1126/sciadv.abb5427 |
0.642 |
|
2020 |
Chen R, Jing J, Siwko S, Huang Y, Zhou Y. Intelligent cell-based therapies for cancer and autoimmune disorders. Current Opinion in Biotechnology. 66: 207-216. PMID 32956902 DOI: 10.1016/J.Copbio.2020.08.012 |
0.655 |
|
2020 |
Ma G, He L, Liu S, Xie J, Huang Z, Jing J, Lee YT, Wang R, Luo H, Han W, Huang Y, Zhou Y. Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. Nature Communications. 11: 1039. PMID 32098964 DOI: 10.1038/S41467-020-14841-9 |
0.681 |
|
2020 |
Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nature Communications. 11: 740. PMID 32029739 DOI: 10.1182/Blood-2019-130586 |
0.66 |
|
2020 |
Haruehanroengra P, Zheng YY, Zhou Y, Huang Y, Sheng J. RNA Modifications and Cancer. Rna Biology. PMID 31994439 DOI: 10.1080/15476286.2020.1722449 |
0.644 |
|
2020 |
Zhang X, Wang X, Wang XQD, Su J, Putluri N, Zhou T, Qu Y, Jeong M, Guzman A, Rosas C, Huang YN, Sreekumar A, Li W, Goodell MA. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. PMID 31932841 DOI: 10.1182/Blood.2019003330 |
0.333 |
|
2019 |
Woodcock CB, Yu D, Hajian T, Li J, Huang Y, Dai N, Corrêa IR, Wu T, Vedadi M, Zhang X, Cheng X. Human MettL3-MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro. Cell Discovery. 5: 63. PMID 31885874 DOI: 10.1038/S41421-019-0136-4 |
0.311 |
|
2019 |
Zeng H, He H, Guo L, Li J, Lee M, Han W, Guzman AG, Zang S, Zhou Y, Zhang X, Goodell MA, King KY, Sun D, Huang Y. Antibiotic treatment ameliorates Ten-eleven Translocation 2 (TET2) loss-of-function associated hematological malignancies. Cancer Letters. PMID 31563562 DOI: 10.1016/J.Canlet.2019.09.013 |
0.667 |
|
2019 |
Fang S, Li J, Xiao Y, Lee M, Guo L, Han W, Li T, Hill MC, Hong T, Mo W, Xu R, Zhang P, Wang F, Chang J, Zhou Y, ... ... Huang Y, et al. Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development. Nature Communications. 10: 4297. PMID 31541101 DOI: 10.1038/S41467-019-12325-Z |
0.683 |
|
2019 |
Jing J, Liu G, Huang Y, Zhou Y. A molecular toolbox for interrogation of membrane contact sites. The Journal of Physiology. PMID 31119749 DOI: 10.1113/Jp277761 |
0.644 |
|
2019 |
Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Research. PMID 31081034 DOI: 10.1093/nar/gkz381 |
0.362 |
|
2019 |
Li JY, Liu YF, Xu HY, Zhang JY, Lv PP, Liu ME, Ying YY, Qian YQ, Li K, Li C, Huang Y, Xu GF, Ding GL, Mao YC, Xu CM, et al. Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis. Journal of Molecular Cell Biology. PMID 31065688 DOI: 10.1093/Jmcb/Mjz035 |
0.322 |
|
2019 |
Liu T, Dong G, Xu F, Han B, Fang H, Huang Y, Zhou Y, Du L, Li M. Discovery of Turn-On Fluorescent Probes for Detecting Bcl-2 Protein. Analytical Chemistry. PMID 30859811 DOI: 10.1021/Acs.Analchem.8B05853 |
0.65 |
|
2019 |
Rajendran P, Johnson GS, Li L, Chen YS, Dashwood WM, Nguyen N, Ulusan AM, Ertem FU, Zhang M, Li J, Sun D, Huang Y, Wang S, Leung HE, Lieberman D, et al. Acetylation of CCAR2 establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition. Cancer Research. PMID 30643017 DOI: 10.1158/0008-5472.Can-18-2003 |
0.343 |
|
2019 |
Johnson GS, Rajendran P, Li L, Chen Y, Dashwood WM, Nguyen N, Ulusan AM, Ertem F, Zhang M, Sun D, Huang Y, Wang S, Leung HE, Lieberman D, Beaver LM, et al. Abstract 2614: CCAR2 acetylation establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition Cancer Research. 79: 2614-2614. DOI: 10.1158/1538-7445.Am2019-2614 |
0.336 |
|
2018 |
Liu Z, Li H, He L, Xiang Y, Tian C, Li C, Tan P, Jing J, Tian Y, Du L, Huang Y, Han L, Li M, Zhou Y. Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma. Cell Chemical Biology. PMID 30639261 DOI: 10.1016/J.Chembiol.2018.11.009 |
0.651 |
|
2018 |
Yang J, Horton JR, Wang D, Ren R, Li J, Sun D, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for effects of CpA modifications on C/EBPβ binding of DNA. Nucleic Acids Research. PMID 30566668 DOI: 10.1093/Nar/Gky1264 |
0.353 |
|
2018 |
Zheng S, Ma G, He L, Zhang T, Li J, Yuan X, Nguyen NT, Huang Y, Zhang X, Gao P, Nwokonko R, Gill DL, Dong H, Zhou Y, Wang Y. Identification of molecular determinants that govern distinct STIM2 activation dynamics. Plos Biology. 16: e2006898. PMID 30444880 DOI: 10.1371/Journal.Pbio.2006898 |
0.688 |
|
2018 |
Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, Lee M, Fang S, Jing J, Johnson G, Sun D, Cao WM, Dashwood R, Han L, Zhou Y, ... ... Huang Y, et al. p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene. PMID 30390073 DOI: 10.1038/S41388-018-0524-5 |
0.649 |
|
2018 |
Ma G, He L, Jing J, Tan P, Huang Y, Zhou Y. Engineered Cross-Linking to Study the Pore Architecture of the CRAC Channel. Methods in Molecular Biology (Clifton, N.J.). 1843: 147-166. PMID 30203285 DOI: 10.1007/978-1-4939-8704-7_13 |
0.664 |
|
2018 |
Nguyen NT, Ma G, Lin E, D'Souza B, Jing J, He L, Huang Y, Zhou Y. CRAC channel-based optogenetics. Cell Calcium. 75: 79-88. PMID 30199756 DOI: 10.1016/J.Ceca.2018.08.007 |
0.691 |
|
2018 |
Ma G, Zhang Q, He L, Nguyen NT, Liu S, Gong Z, Huang Y, Zhou Y. Genetically encoded tags for real time dissection of protein assembly in living cells. Chemical Science. 9: 5551-5555. PMID 30061986 DOI: 10.1039/C8Sc00839F |
0.653 |
|
2018 |
Gu T, Lin X, Cullen SM, Luo M, Jeong M, Estecio M, Shen J, Hardikar S, Sun D, Su J, Rux D, Guzman A, Lee M, Qi LS, Chen JJ, ... ... Huang Y, et al. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biology. 19: 88. PMID 30001199 DOI: 10.1186/S13059-018-1464-7 |
0.389 |
|
2018 |
Nguyen NT, Han W, Cao WM, Wang Y, Wen S, Huang Y, Li M, Du L, Zhou Y. Store-Operated Calcium Entry Mediated by ORAI and STIM. Comprehensive Physiology. 8: 981-1002. PMID 29978901 DOI: 10.1002/Cphy.C170031 |
0.666 |
|
2018 |
Zheng S, Zhou L, Ma G, Zhang T, Liu J, Li J, Nguyen NT, Zhang X, Li W, Nwokonko R, Zhou Y, Zhao F, Liu J, Huang Y, Gill DL, et al. Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines. Pflugers Archiv : European Journal of Physiology. PMID 29934936 DOI: 10.1007/S00424-018-2165-5 |
0.371 |
|
2018 |
Zhou Y, Ma G, Liu J, Ke Y, Liu X, Li M, Wang F, Han G, Huang Y, Wang Y. Optogenetic Control of Voltage Gated Calcium Channels. Angewandte Chemie (International Ed. in English). PMID 29569306 DOI: 10.1002/Anie.201713080 |
0.673 |
|
2018 |
Nguyen NT, He L, Martinez-Moczygemba M, Huang Y, Zhou Y. Rewiring calcium signaling for precise transcriptional reprogramming. Acs Synthetic Biology. PMID 29489336 DOI: 10.1021/Acssynbio.7B00467 |
0.681 |
|
2018 |
Li J, Wu X, Zhou Y, Lee M, Guo L, Han W, Mo W, Cao WM, Sun D, Xie R, Huang Y. Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC. Nucleic Acids Research. PMID 29394393 DOI: 10.1093/Nar/Gky063 |
0.684 |
|
2018 |
Fang S, Xiao Y, Li J, Li T, Zeng H, Han W, Zhou Y, Sun D, Martin JM, Huang Y. Tet2 Deficiency in Macrophages Undermines Heart Repair after Infarction Blood. 132: 2394-2394. DOI: 10.1182/Blood-2018-99-115358 |
0.614 |
|
2018 |
Ma G, Liu J, Ke Y, Liu X, Li M, Wang F, Han G, Huang Y, Wang Y, Zhou Y. Inside Back Cover: Optogenetic Control of Voltage-Gated Calcium Channels (Angew. Chem. Int. Ed. 24/2018) Angewandte Chemie International Edition. 57: 7255-7255. DOI: 10.1002/Anie.201804536 |
0.638 |
|
2018 |
Ma G, Liu J, Ke Y, Liu X, Li M, Wang F, Han G, Huang Y, Wang Y, Zhou Y. Innenrücktitelbild: Optogenetic Control of Voltage-Gated Calcium Channels (Angew. Chem. 24/2018) Angewandte Chemie. 130: 7375-7375. DOI: 10.1002/Ange.201804536 |
0.637 |
|
2017 |
Lee M, Zhou Y, Huang Y. An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling. Journal of Visualized Experiments : Jove. PMID 29286410 DOI: 10.3791/56858 |
0.702 |
|
2017 |
He L, Jing J, Zhu L, Tan P, Ma G, Zhang Q, Nguyen NT, Wang J, Zhou Y, Huang Y. Optical control of membrane tethering and interorganellar communication at nanoscales. Chemical Science. 8: 5275-5281. PMID 28959426 DOI: 10.1039/C7Sc01115F |
0.651 |
|
2017 |
Ma G, Wen S, Huang Y, Zhou Y. The STIM-Orai Pathway: Light-Operated Ca(2+) Entry Through Engineered CRAC Channels. Advances in Experimental Medicine and Biology. 993: 117-138. PMID 28900912 DOI: 10.1007/978-3-319-57732-6_7 |
0.682 |
|
2017 |
Zang S, Li J, Yang H, Zeng H, Han W, Zhang J, Lee M, Moczygemba M, Isgandarova S, Yang Y, Zhou Y, Rao A, You MJ, Sun D, Huang Y. Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis. The Journal of Clinical Investigation. PMID 28691928 DOI: 10.1172/Jci92026 |
0.711 |
|
2017 |
Huang A, Wu H, Iriyama T, Zhang Y, Sun K, Song A, Liu H, Peng Z, Tang L, Lee M, Huang Y, Ni X, Kellems RE, Xia Y. Elevated Adenosine Induces Placental DNA Hypomethylation Independent of A2B Receptor Signaling in Preeclampsia. Hypertension (Dallas, Tex. : 1979). PMID 28507174 DOI: 10.1161/Hypertensionaha.117.09536 |
0.328 |
|
2017 |
Lee M, Li J, Liang Y, Ma G, Zhang J, He L, Liu Y, Li Q, Li M, Sun D, Zhou Y, Huang Y. An engineered split-TET2 enzyme for inducible epigenetic remodeling. Journal of the American Chemical Society. PMID 28294608 DOI: 10.1021/Jacs.7B01459 |
0.686 |
|
2017 |
Ma G, Zheng S, Ke Y, Zhou L, He L, Huang Y, Wang Y, Zhou Y. Molecular determinants for STIM1 activation during store-operated Ca2+ entry. Current Molecular Medicine. PMID 28231751 DOI: 10.2174/1566524017666170220103731 |
0.341 |
|
2017 |
Ma G, Wen S, He L, Huang Y, Wang Y, Zhou Y. Optogenetic toolkit for precise control of calcium signaling. Cell Calcium. PMID 28104276 DOI: 10.1016/J.Ceca.2017.01.004 |
0.686 |
|
2017 |
Zang S, Li J, Yang H, Han W, Zhang J, Lee M, Zhou Y, Sun D, Huang Y. Abstract 5379: TET2 loss and the lymphoma-associated RHOA mutation cooperate to disrupt CD4+ T cell function Cancer Research. 77: 5379-5379. DOI: 10.1158/1538-7445.Am2017-5379 |
0.661 |
|
2017 |
He L, Nguyen N, Han G, Huang Y, Zhou Y. Abstract 1652: Optogenetic immunoengineering to develop improved anti-cancer immunotherapy Cancer Research. 77: 1652-1652. DOI: 10.1158/1538-7445.Am2017-1652 |
0.687 |
|
2017 |
Nguyen NT, He L, Liang Y, Huang Y, Zhou Y. Rewiring Calcium Signaling for Genome Editing and Transcriptional Reprogramming Biophysical Journal. 112: 398a. DOI: 10.1016/J.Bpj.2016.11.2161 |
0.692 |
|
2017 |
Liang Y, Lee M, Zhou Y, Huang Y. An Engineered TET Enzyme for Inducible Epigenomic Remodeling and Editing Biophysical Journal. 112: 306a-307a. DOI: 10.1016/J.Bpj.2016.11.1658 |
0.687 |
|
2016 |
Basanta-Sanchez M, Wang R, Liu Z, Ye X, Li M, Shi X, Agris P, Zhou Y, Huang Y, Sheng J. TET1-mediated Oxidation of 5-formylcytosine (5fC) to 5-carboxycytosine (5caC) in RNA. Chembiochem : a European Journal of Chemical Biology. PMID 27805801 DOI: 10.1002/Cbic.201600328 |
0.649 |
|
2016 |
Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nature Genetics. PMID 27428748 DOI: 10.1038/Ng.3610 |
0.522 |
|
2016 |
Äijö T, Huang Y, Mannerström H, Chavez L, Tsagaratou A, Rao A, Lähdesmäki H. A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways. Genome Biology. 17: 49. PMID 26975309 DOI: 10.1186/S13059-016-0911-6 |
0.531 |
|
2016 |
Yue X, Trifari S, Äijö T, Tsagaratou A, Pastor WA, Zepeda-Martínez JA, Lio CJ, Li X, Huang Y, Vijayanand P, Lähdesmäki H, Rao A. Control of Foxp3 stability through modulation of TET activity. The Journal of Experimental Medicine. PMID 26903244 DOI: 10.1084/Jem.20151438 |
0.718 |
|
2016 |
He L, Zhang Y, Ma G, Tan P, Wang Y, Huang Y, Hogan P, Han G, Zhou Y. Near-Infrared Photoactivatable Control of Calcium Signaling Biophysical Journal. 110: 360a. DOI: 10.1016/J.Bpj.2015.11.1941 |
0.665 |
|
2016 |
Jing J, He L, Sun A, Quintana A, Ding Y, Ma G, Tan P, Chen L, Zhang S, Huang Y, Dong M, Walker C, Hogan P, Wang Y, Zhou Y. Proteomic Mapping and Optogenetic Control of ER-PM Junctions in Living Cells Biophysical Journal. 110: 258a. DOI: 10.1016/J.Bpj.2015.11.1415 |
0.673 |
|
2015 |
He L, Zhang Y, Ma G, Tan P, Li Z, Zhang S, Wu X, Jing J, Fang S, Zhou L, Wang Y, Huang Y, Hogan P, Han G, Zhou Y. Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation. Elife. 4. PMID 26646180 DOI: 10.7554/Elife.10024 |
0.691 |
|
2015 |
Jing J, He L, Sun A, Quintana A, Ding Y, Ma G, Tan P, Liang X, Zheng X, Chen L, Shi X, Zhang SL, Zhong L, Huang Y, Dong MQ, et al. Proteomic mapping of ER-PM junctions identifies STIMATE as a regulator of Ca(2+) influx. Nature Cell Biology. PMID 26322679 DOI: 10.1038/Ncb3234 |
0.682 |
|
2015 |
Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, et al. The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nature Cell Biology. 17: 545-57. PMID 25915124 DOI: 10.1038/Ncb3147 |
0.525 |
|
2015 |
He L, Zhang Y, Ma G, Tan P, Li Z, Zang S, Wu X, Jing J, Fang S, Zhou L, Wang Y, Huang Y, Hogan PG, Han G, Zhou Y. Author response: Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation Elife. DOI: 10.7554/Elife.10024.023 |
0.655 |
|
2014 |
Chavez L, Huang Y, Luong K, Agarwal S, Iyer LM, Pastor WA, Hench VK, Frazier-Bowers SA, Korol E, Liu S, Tahiliani M, Wang Y, Clark TA, Korlach J, Pukkila PJ, et al. Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea. Proceedings of the National Academy of Sciences of the United States of America. 111: E5149-58. PMID 25406324 DOI: 10.1073/Pnas.1419513111 |
0.773 |
|
2014 |
Huang Y, Rao A. Connections between TET proteins and aberrant DNA modification in cancer. Trends in Genetics : Tig. 30: 464-74. PMID 25132561 DOI: 10.1016/J.Tig.2014.07.005 |
0.53 |
|
2014 |
Tsagaratou A, Äijö T, Lio CW, Yue X, Huang Y, Jacobsen SE, Lähdesmäki H, Rao A. Dissecting the dynamic changes of 5-hydroxymethylcytosine in T-cell development and differentiation. Proceedings of the National Academy of Sciences of the United States of America. 111: E3306-15. PMID 25071199 DOI: 10.1073/Pnas.1412327111 |
0.533 |
|
2014 |
Huang Y, Chavez L, Chang X, Wang X, Pastor WA, Kang J, Zepeda-Martínez JA, Pape UJ, Jacobsen SE, Peters B, Rao A. Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 1361-6. PMID 24474761 DOI: 10.1073/Pnas.1322921111 |
0.738 |
|
2014 |
Zhang C, Huang Y, Jiang Y, Mulpuri N, Wei L, Hamelberg D, Brown EM, Yang JJ. Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium. The Journal of Biological Chemistry. 289: 5296-309. PMID 24394414 DOI: 10.1074/Jbc.M113.537357 |
0.323 |
|
2014 |
Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, et al. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nature Genetics. 46: 17-23. PMID 24270360 DOI: 10.1038/Ng.2836 |
0.547 |
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2014 |
Zhang X, Jeong M, Su J, Ko MG, Huang Y, Park HJ, Rao A, Li W, Goodell MA. Dnmt3a and Tet2 interact to Repress differentiation lineage-specific transcriptional factors in Hematopoietic Stem Cells By the Regulation of Epigenome Blood. 124: 242-242. DOI: 10.1182/Blood.V124.21.242.242 |
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2013 |
Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, Johnson ND, Lucero J, Huang Y, Dwork AJ, Schultz MD, Yu M, Tonti-Filippini J, Heyn H, Hu S, Wu JC, et al. Global epigenomic reconfiguration during mammalian brain development. Science (New York, N.Y.). 341: 1237905. PMID 23828890 DOI: 10.1126/Science.1237905 |
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2013 |
Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT. Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells. Cell Stem Cell. 12: 470-8. PMID 23415914 DOI: 10.1016/J.Stem.2013.01.016 |
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2013 |
Jeong M, Sun D, Luo M, Huang Y, Ko M, Chavez L, Challen GA, Rodriguez B, Zhang X, Yang L, Wang H, Chen R, Hannah R, Kim S, Lee J, et al. Large Conserved Domains Of Low DNA Methylation Maintained By 5-Hydroxymethycytosine and Dnmt3a Blood. 122: 2406-2406. DOI: 10.1182/Blood.V122.21.2406.2406 |
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2012 |
Huang Y, Rao A. New functions for DNA modifications by TET-JBP. Nature Structural & Molecular Biology. 19: 1061-4. PMID 23132381 DOI: 10.1038/Nsmb.2437 |
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2012 |
Pastor WA, Huang Y, Henderson HR, Agarwal S, Rao A. The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1909-17. PMID 23018194 DOI: 10.1038/nprot.2012.104 |
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2012 |
Huang Y, Pastor WA, Zepeda-Martínez JA, Rao A. The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine. Nature Protocols. 7: 1897-908. PMID 23018193 DOI: 10.1038/Nprot.2012.103 |
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2012 |
Zhang C, Hannan F, Huang Y, Jiang Y, Nagaraju M, Thakker R, Hamelberg D, Brown E, Yang J. Disease Related Mutations Adjacent to Predicted Multiple Ca2+ Binding Sites of Ca2+-Sensing Receptor Altering Intracellular Ca2+ Oscillations via Extracellular Calcium and Amino Acid Signaling Biophysical Journal. 102: 507a. DOI: 10.1016/J.Bpj.2011.11.2779 |
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2011 |
Tang S, Wong HC, Wang ZM, Huang Y, Zou J, Zhuo Y, Pennati A, Gadda G, Delbono O, Yang JJ. Design and application of a class of sensors to monitor Ca2+ dynamics in high Ca2+ concentration cellular compartments. Proceedings of the National Academy of Sciences of the United States of America. 108: 16265-70. PMID 21914846 DOI: 10.1073/Pnas.1103015108 |
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2011 |
Jankowska AM, Makishima H, Tiu RV, Szpurka H, Huang Y, Traina F, Visconte V, Sugimoto Y, Prince C, O'Keefe C, Hsi ED, List A, Sekeres MA, Rao A, McDevitt MA, et al. Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A. Blood. 118: 3932-41. PMID 21828135 DOI: 10.1182/Blood-2010-10-311019 |
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2011 |
Pastor WA, Pape UJ, Huang Y, Henderson HR, Lister R, Ko M, McLoughlin EM, Brudno Y, Mahapatra S, Kapranov P, Tahiliani M, Daley GQ, Liu XS, Ecker JR, Milos PM, et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature. 473: 394-7. PMID 21552279 DOI: 10.1038/Nature10102 |
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2011 |
Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell. 8: 200-13. PMID 21295276 DOI: 10.1016/J.Stem.2011.01.008 |
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2011 |
Rao A, Ko M, Pastor W, Huang Y. TET2: Mechanism and Functional Consequences of Hydroxymethylation Blood. 118: SCI-32-SCI-32. DOI: 10.1182/Blood.V118.21.Sci-32.Sci-32 |
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2011 |
Jankowska AM, Huang Y, Ko M, Pape UJ, Makishima H, Szpurka H, Traina F, Visconte V, Tiu RV, Sekeres MA, Rao A, Maciejewski JP. Mechanisms of Defective Hydroxylation of 5-Methylcytosine in MDS Include Pathways Other Than TET2 and IDH1/2 Blood. 118: 462-462. DOI: 10.1182/Blood.V118.21.462.462 |
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2011 |
Zhang C, Huang Y, Jiang Y, Wong H, Wang X, Castiblanco A, Wei L, Brown E, Yang JJ. Differential Activation of Intracellular Calcium Oscillations by Multiple Calcium and L-Phenylalanine Binding Sites Located at the Extracellular Domain of Calcium-Sensing-Receptor Biophysical Journal. 100: 86a. DOI: 10.1016/J.Bpj.2010.12.676 |
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2010 |
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS, Aravind L, Agarwal S, Maciejewski JP, Rao A. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature. 468: 839-43. PMID 21057493 DOI: 10.1038/Nature09586 |
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2010 |
Huang Y, Zhou Y, Wong HC, Castiblanco A, Chen Y, Brown EM, Yang JJ. Calmodulin regulates Ca2+-sensing receptor-mediated Ca2+ signaling and its cell surface expression. The Journal of Biological Chemistry. 285: 35919-31. PMID 20826781 DOI: 10.1074/Jbc.M110.147918 |
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2010 |
Jiang Y, Huang Y, Wong HC, Zhou Y, Wang X, Yang J, Hall RA, Brown EM, Yang JJ. Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation. The Journal of Biological Chemistry. 285: 33463-74. PMID 20705606 DOI: 10.1074/Jbc.M110.147033 |
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2010 |
Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. Plos One. 5: e8888. PMID 20126651 DOI: 10.1371/Journal.Pone.0008888 |
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2010 |
Zhou Y, Tzeng WP, Wong HC, Ye Y, Jiang J, Chen Y, Huang Y, Suppiah S, Frey TK, Yang JJ. Calcium-dependent association of calmodulin with the rubella virus nonstructural protease domain. The Journal of Biological Chemistry. 285: 8855-68. PMID 20086014 DOI: 10.1074/Jbc.M109.097063 |
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2010 |
Zhou Y, Meraner P, Kwon HT, Machnes D, Oh-hora M, Zimmer J, Huang Y, Stura A, Rao A, Hogan PG. STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nature Structural & Molecular Biology. 17: 112-6. PMID 20037597 DOI: 10.1038/Nsmb.1724 |
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2010 |
Jankowska A, Makishima H, Tiu RV, Szpurka H, Huang Y, Sugimoto Y, Prince C, O'Keefe CL, Hsi E, List AF, Sekeres MA, Rao A, McDevitt MA, Maciejewski JP. Mutational Spectrum In Chronic Myelomonocytic Leukemia Includes Genes Associated with Epigenetic Regulation Such as UTX and EZH2 Blood. 116: 611-611. DOI: 10.1182/Blood.V116.21.611.611 |
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2010 |
Zhou Y, Meraner P, Kwon HT, Machnes D, Oh-hora M, Zimmer J, Huang Y, Stura A, Rao A, Hogan PG. Minimal Requirement for Store-Operated Calcium Entry: STIM1 Gates ORAI1 Channels in Vitro Biophysical Journal. 98: 97a. DOI: 10.1016/J.Bpj.2009.12.546 |
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2010 |
Tang S, Wong H, Zou J, Huang Y, Yang JJ. Rational Design and Structrual Analysis of Ca2+ Biosensor and Application in Skeletal Muscle Cells Biophysical Journal. 98: 296a-297a. DOI: 10.1016/J.Bpj.2009.12.1614 |
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2009 |
Huang Y, Zhou Y, Wong HC, Chen Y, Chen Y, Wang S, Castiblanco A, Liu A, Yang JJ. A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+. The Febs Journal. 276: 5589-97. PMID 19694801 DOI: 10.1111/J.1742-4658.2009.07240.X |
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2009 |
Zhou Y, Yang W, Lurtz MM, Chen Y, Jiang J, Huang Y, Louis CF, Yang JJ. Calmodulin mediates the Ca2+-dependent regulation of Cx44 gap junctions. Biophysical Journal. 96: 2832-48. PMID 19348766 DOI: 10.1016/J.Bpj.2008.12.3941 |
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2009 |
Huang Y, Zhou Y, Castiblanco A, Yang W, Brown EM, Yang JJ. Multiple Ca(2+)-binding sites in the extracellular domain of the Ca(2+)-sensing receptor corresponding to cooperative Ca(2+) response. Biochemistry. 48: 388-98. PMID 19102677 DOI: 10.1021/Bi8014604 |
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2009 |
Zhou Y, Tzeng WP, Ye Y, Huang Y, Li S, Chen Y, Frey TK, Yang JJ. A cysteine-rich metal-binding domain from rubella virus non-structural protein is essential for viral protease activity and virus replication. The Biochemical Journal. 417: 477-83. PMID 18795894 DOI: 10.1042/Bj20081468 |
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2009 |
Zou J, Delgado M, Huang Y, Tang S, Jiang Y, McIntyre B, Wang A, Yang JJ. Chromophore Formation of Fluorescence Proteins and Its Application of Developing Ca2+ Sensors Biophysical Journal. 96: 120a. DOI: 10.1016/J.Bpj.2008.12.529 |
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2009 |
Huang Y, Zhou Y, Castiblanco A, Wong H, Chen Y, Yang W, Brown EM, Yang JJ. Integration of Extracellular and Intracellular Calcium Signals via Calcium-Sensing Receptor (CaSR) Biophysical Journal. 96: 117a. DOI: 10.1016/J.Bpj.2008.12.515 |
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2009 |
Tang S, Wong H, Huang Y, Zou J, Lee H, Yang JJ. Rational Design of Ca2+ Biosensor Biophysical Journal. 96: 539a-540a. DOI: 10.1016/J.Bpj.2008.12.2787 |
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2007 |
Zou J, Hofer AM, Lurtz MM, Gadda G, Ellis AL, Chen N, Huang Y, Holder A, Ye Y, Louis CF, Welshhans K, Rehder V, Yang JJ. Developing sensors for real-time measurement of high Ca2+ concentrations. Biochemistry. 46: 12275-88. PMID 17924653 DOI: 10.1021/Bi7007307 |
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2007 |
Zhou Y, Yang W, Lurtz MM, Ye Y, Huang Y, Lee HW, Chen Y, Louis CF, Yang JJ. Identification of the calmodulin binding domain of connexin 43. The Journal of Biological Chemistry. 282: 35005-17. PMID 17901047 DOI: 10.1074/Jbc.M707728200 |
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2007 |
Huang Y, Zhou Y, Yang W, Butters R, Lee HW, Li S, Castiblanco A, Brown EM, Yang JJ. Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor. The Journal of Biological Chemistry. 282: 19000-10. PMID 17478419 DOI: 10.1074/Jbc.M701096200 |
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2004 |
Yang J, Xu ZP, Huang Y, Hamrick HE, Duerksen-Hughes PJ, Yu YN. ATM and ATR: sensing DNA damage. World Journal of Gastroenterology. 10: 155-60. PMID 14716813 DOI: 10.3748/Wjg.V10.I2.155 |
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