Year |
Citation |
Score |
2023 |
Si Y, Wang Y, Tian Q, Wang Q, Pollard JM, Srivastava PK, Esser-Kahn AP, Collier JH, Sperling AI, Chong AS. Lung cDC1 and cDC2 dendritic cells priming naive CD8 T cells in situ prior to migration to draining lymph nodes. Cell Reports. 42: 113299. PMID 37864794 DOI: 10.1016/j.celrep.2023.113299 |
0.48 |
|
2023 |
Yoon YM, Velez TE, Upadhyay V, Vazquez SE, Lee CT, Selvan KC, Law CS, Blaine KM, Hollinger MK, Decker DC, Clark MR, Strek ME, Guzy RD, Adegunsoye A, Noth I, ... ... Sperling AI, et al. Antigenic responses are hallmarks of fibrotic interstitial lung diseases independent of underlying etiologies. Medrxiv : the Preprint Server For Health Sciences. PMID 37214861 DOI: 10.1101/2023.05.08.23289640 |
0.349 |
|
2022 |
Jia G, Zhong X, Im HK, Schoettler N, Pividori M, Hogarth DK, Sperling AI, White SR, Naureckas ET, Lyttle CS, Terao C, Kamatani Y, Akiyama M, Matsuda K, Kubo M, et al. Discerning asthma endotypes through comorbidity mapping. Nature Communications. 13: 6712. PMID 36344522 DOI: 10.1038/s41467-022-33628-8 |
0.424 |
|
2022 |
Camacho DF, Velez TE, Hollinger MK, Wang E, Howard CL, Darnell EP, Kennedy DE, Krishack PA, Hrusch CL, Clark MR, Moon JJ, Sperling AI. IRF4 expression by lung dendritic cells drives acute but not TRM-dependent memory Th2 responses. Jci Insight. PMID 36194494 DOI: 10.1172/jci.insight.140384 |
0.335 |
|
2021 |
Aneas I, Decker DC, Howard CL, Sobreira DR, Sakabe NJ, Blaine KM, Stein MM, Hrusch CL, Montefiori LE, Tena J, Magnaye KM, Clay SM, Gern JE, Jackson DJ, Altman MC, ... ... Sperling AI, et al. Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region. Nature Communications. 12: 6115. PMID 34675193 DOI: 10.1038/s41467-021-26347-z |
0.47 |
|
2021 |
Kasal DN, Liang Z, Hollinger MK, O'Leary CY, Lisicka W, Sperling AI, Bendelac A. A enhancer necessary for ILC2 development and function. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34353913 DOI: 10.1073/pnas.2106311118 |
0.393 |
|
2020 |
Lee TH, Yeh CF, Lee YT, Shih YC, Chen YT, Hung CT, You MY, Wu PC, Shentu TP, Huang RT, Lin YS, Wu YF, Lin SJ, Lu FL, Tsao PN, ... ... Sperling AI, et al. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nature Communications. 11: 4254. PMID 32848143 DOI: 10.1038/S41467-020-18047-X |
0.313 |
|
2020 |
Si Y, Tian Q, Zhao F, Kelly SH, Shores LS, Camacho DF, Sperling AI, Andrade MS, Collier JH, Chong AS. Adjuvant-free nanofiber vaccine induces in situ lung dendritic cell activation and T17 responses. Science Advances. 6: eaba0995. PMID 32821819 DOI: 10.1126/Sciadv.Aba0995 |
0.37 |
|
2020 |
Maisel K, Hrusch CL, Medellin JEG, Potin L, Chapel DB, Nurmi H, Camacho DF, Gleyzer R, Alitalo K, Sperling AI, Swartz MA. Pro-lymphangiogenic VEGFR-3 signaling modulates memory T cell responses in allergic airway inflammation. Mucosal Immunology. PMID 32518367 DOI: 10.1038/S41385-020-0308-4 |
0.482 |
|
2019 |
Bonham CA, Hrusch CL, Blaine KM, Manns ST, Vij R, Oldham JM, Churpek MM, Strek ME, Noth I, Sperling AI. T cell Co-Stimulatory molecules ICOS and CD28 stratify idiopathic pulmonary fibrosis survival. Respiratory Medicine: X. 1. PMID 32455343 DOI: 10.1016/j.yrmex.2019.100002 |
0.417 |
|
2019 |
Schoettler N, Hrusch CL, Blaine KM, Sperling AI, Ober C. Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. Communications Biology. 2: 411. PMID 31925217 DOI: 10.1038/s42003-019-0657-2 |
0.598 |
|
2019 |
Schoettler N, Hrusch CL, Blaine KM, Sperling AI, Ober C. Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. Communications Biology. 2: 411. PMID 31754641 DOI: 10.1038/s42003-019-0657-2 |
0.598 |
|
2019 |
Hrusch CL, Stein MM, Gozdz J, Holbreich M, Von Mutius E, Vercelli D, Ober C, Sperling AI. T cell phenotypes are associated with serum IgE levels in Amish and Hutterite children. The Journal of Allergy and Clinical Immunology. PMID 31401285 DOI: 10.1016/J.Jaci.2019.07.034 |
0.583 |
|
2019 |
Sharma A, Laxman B, Naureckas ET, Hogarth DK, Sperling AI, Solway J, Ober C, Gilbert JA, White SR. Associations between fungal and bacterial microbiota of airways and asthma endotypes. The Journal of Allergy and Clinical Immunology. PMID 31279011 DOI: 10.1016/J.Jaci.2019.06.025 |
0.568 |
|
2019 |
White SR, Laxman B, Naureckas ET, Hogarth DK, Solway J, Sperling AI, Ober C. Evidence for an IL-6 high asthma phenotype in asthma patients of African ancestry. The Journal of Allergy and Clinical Immunology. PMID 31029772 DOI: 10.1016/J.Jaci.2019.04.007 |
0.516 |
|
2019 |
Krishack PA, Louviere TJ, Decker TS, Kuzel TG, Greenberg JA, Camacho DF, Hrusch CL, Sperling AI, Verhoef PA. Protection against Staphylococcus aureus bacteremia-induced mortality depends on ILC2s and eosinophils. Jci Insight. PMID 30721149 DOI: 10.1172/Jci.Insight.124168 |
0.455 |
|
2018 |
Reyfman PA, Walter JM, Joshi N, Anekalla KR, McQuattie-Pimentel AC, Chiu S, Fernandez R, Akbarpour M, Chen CI, Ren Z, Verma R, Abdala-Valencia H, Nam K, Chi M, Han S, ... ... Sperling AI, et al. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 30554520 DOI: 10.1164/Rccm.201712-2410Oc |
0.328 |
|
2018 |
Williams JW, Ferreira CM, Blaine KM, Rayon C, Velázquez F, Tong J, Peter ME, Sperling AI. Non-apoptotic Fas (CD95) Signaling on T Cells Regulates the Resolution of Th2-Mediated Inflammation. Frontiers in Immunology. 9: 2521. PMID 30443253 DOI: 10.3389/Fimmu.2018.02521 |
0.521 |
|
2018 |
Ferreira CM, Williams JW, Tong J, Rayon C, Blaine KM, Sperling AI. Allergen Exposure in Lymphopenic Fas-Deficient Mice Results in Persistent Eosinophilia Due to Defects in Resolution of Inflammation. Frontiers in Immunology. 9: 2395. PMID 30425708 DOI: 10.3389/Fimmu.2018.02395 |
0.504 |
|
2018 |
Adegunsoye A, Oldham JM, Bonham C, Hrusch C, Nolan P, Klejch W, Bellam S, Mehta U, Thakrar K, Pugashetti JV, Husain AN, Montner SM, Straus CM, Vij R, Sperling AI, et al. Prognosticating Outcomes in Interstitial Lung Disease by Mediastinal Lymph Node Assessment: An Observational Cohort Study with Independent Validation. American Journal of Respiratory and Critical Care Medicine. PMID 30216085 DOI: 10.1164/Rccm.201804-0761Oc |
0.323 |
|
2018 |
Stein MM, Hrusch CL, Sperling AI, Ober C. Effects of an FcγRIIA polymorphism on leukocyte gene expression and cytokine responses to anti-CD3 and anti-CD28 antibodies. Genes and Immunity. PMID 29977032 DOI: 10.1038/S41435-018-0038-8 |
0.581 |
|
2018 |
Greenberg JA, Hrusch CL, Jaffery MR, David MZ, Daum RS, Hall JB, Kress JP, Sperling AI, Verhoef PA. Distinct T-helper cell responses to Staphylococcus aureus bacteremia reflect immunologic comorbidities and correlate with mortality. Critical Care (London, England). 22: 107. PMID 29695270 DOI: 10.1186/S13054-018-2025-X |
0.324 |
|
2017 |
Ober C, Sperling AI, von Mutius E, Vercelli D. Immune development and environment: lessons from Amish and Hutterite children. Current Opinion in Immunology. 48: 51-60. PMID 28843541 DOI: 10.1016/J.Coi.2017.08.003 |
0.496 |
|
2017 |
Hrusch CL, Manns ST, Bryazka D, Casaos J, Bonham CA, Jaffery MR, Blaine KM, Mills KAM, Verhoef PA, Adegunsoye AO, Williams JW, Tjota MY, Moore TV, Strek ME, Noth I, ... Sperling AI, et al. ICOS protects against mortality from acute lung injury through activation of IL-5(+) ILC2s. Mucosal Immunology. PMID 28488693 DOI: 10.1038/Mi.2017.42 |
0.731 |
|
2017 |
White SR, Nicodemus-Johnson J, Laxman B, Denner DR, Naureckas ET, Hogarth DK, Stern R, Minc A, Solway J, Sperling A, Ober C. Elevated levels of Soluble Human Leukocyte Antigen-G (sHLA-G) in the Airways are a Marker for a Low-inflammatory Endotype of Asthma. The Journal of Allergy and Clinical Immunology. PMID 28363527 DOI: 10.1016/J.Jaci.2017.02.031 |
0.499 |
|
2016 |
Nicodemus-Johnson J, Myers RA, Sakabe NJ, Sobreira DR, Hogarth DK, Naureckas ET, Sperling AI, Solway J, White SR, Nobrega MA, Nicolae DL, Gilad Y, Ober C. DNA methylation in lung cells is associated with asthma endotypes and genetic risk. Jci Insight. 1: e90151. PMID 27942592 DOI: 10.1172/Jci.Insight.90151 |
0.517 |
|
2016 |
Adegunsoye A, Hrusch CL, Bonham CA, Jaffery MR, Blaine KM, Sullivan M, Churpek MM, Strek ME, Noth I, Sperling AI. Skewed Lung CCR4 to CCR6 CD4(+) T Cell Ratio in Idiopathic Pulmonary Fibrosis Is Associated with Pulmonary Function. Frontiers in Immunology. 7: 516. PMID 27933058 DOI: 10.3389/Fimmu.2016.00516 |
0.466 |
|
2016 |
Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques Dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, ... ... Sperling AI, et al. Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children. The New England Journal of Medicine. 375: 411-21. PMID 27518660 DOI: 10.1056/Nejmoa1508749 |
0.553 |
|
2016 |
Gozdz J, Holbreich M, Metwali N, Thorne PS, Sperling AI, Martinez FD, Ober C, von Mutius E, Vercelli D. Amish and Hutterite Environmental Farm Products Have Opposite Effects on Experimental Models of Asthma. Annals of the American Thoracic Society. 13: S99. PMID 27027969 DOI: 10.1513/Annalsats.201509-581Mg |
0.488 |
|
2015 |
Verhoef PA, Constantinides MG, McDonald BD, Urban JF, Sperling AI, Bendelac A. Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice. The Journal of Allergy and Clinical Immunology. PMID 26602165 DOI: 10.1016/J.Jaci.2015.07.050 |
0.403 |
|
2015 |
Nicodemus-Johnson J, Naughton KA, Sudi J, Hogarth K, Naurekas ET, Nicolae DL, Sperling AI, Solway J, White SR, Ober C. Genome-wide Methylation Study Identifies an IL-13 Induced Epigenetic Signature in Asthmatic Airways. American Journal of Respiratory and Critical Care Medicine. PMID 26474238 DOI: 10.1164/Rccm.201506-1243Oc |
0.542 |
|
2015 |
Edelblum KL, Singh G, Odenwald MA, Lingaraju A, El Bissati K, McLeod R, Sperling AI, Turner JR. γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. Gastroenterology. 148: 1417-26. PMID 25747597 DOI: 10.1053/J.Gastro.2015.02.053 |
0.446 |
|
2015 |
Hrusch CL, Tjota MY, Sperling AI. The role of dendritic cells and monocytes in the maintenance and loss of respiratory tolerance. Current Allergy and Asthma Reports. 15: 494. PMID 25430955 DOI: 10.1007/S11882-014-0494-9 |
0.398 |
|
2015 |
Broz M, Binnewies M, Boldajipour B, Nelson A, Pollock J, Erle D, Barczak A, Rosenblum M, Daud A, Barber D, Amigorena S, Veer LJv', Sperling A, Wolf D, Krummel MF. Abstract B65: Dissecting the tumor myeloid compartment reveals rare activating antigen presenting cells, critical for T cell immunity Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-B65 |
0.423 |
|
2014 |
Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity. Cancer Cell. 26: 938. PMID 28898680 DOI: 10.1016/j.ccell.2014.11.010 |
0.337 |
|
2014 |
Broz ML, Binnewies M, Boldajipour B, Nelson AE, Pollack JL, Erle DJ, Barczak A, Rosenblum MD, Daud A, Barber DL, Amigorena S, Van't Veer LJ, Sperling AI, Wolf DM, Krummel MF. Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity. Cancer Cell. 26: 638-52. PMID 25446897 DOI: 10.1016/J.Ccell.2014.09.007 |
0.437 |
|
2014 |
Tjota MY, Sperling AI. Distinct dendritic cell subsets actively induce Th2 polarization. Current Opinion in Immunology. 31: 44-50. PMID 25290173 DOI: 10.1016/J.Coi.2014.09.006 |
0.425 |
|
2014 |
Tjota MY, Hrusch CL, Blaine KM, Williams JW, Barrett NA, Sperling AI. Signaling through FcRγ-associated receptors on dendritic cells drives IL-33-dependent TH2-type responses. The Journal of Allergy and Clinical Immunology. 134: 706-713.e8. PMID 25088053 DOI: 10.1016/J.Jaci.2014.06.013 |
0.459 |
|
2014 |
Chen B, Moore TV, Li Z, Sperling AI, Zhang C, Andrade J, Rodriguez A, Bahroos N, Huang Y, Morrisey EE, Gruber PJ, Solway J. Gata5 deficiency causes airway constrictor hyperresponsiveness in mice. American Journal of Respiratory Cell and Molecular Biology. 50: 787-95. PMID 24199649 DOI: 10.1165/Rcmb.2013-0294Oc |
0.752 |
|
2014 |
Poroyko V, Semenyuk E, Xu Z, Sperling A, Alegre M, Chong A, Garrity E, White S, Bhorade S. Post-Transplant Dynamics of Pulmonary Microbiota Annals of the American Thoracic Society. 11: S74-S74. DOI: 10.1513/Annalsats.201307-238Mg |
0.49 |
|
2013 |
Williams JW, Tjota MY, Clay BS, Vander Lugt B, Bandukwala HS, Hrusch CL, Decker DC, Blaine KM, Fixsen BR, Singh H, Sciammas R, Sperling AI. Transcription factor IRF4 drives dendritic cells to promote Th2 differentiation. Nature Communications. 4: 2990. PMID 24356538 DOI: 10.1038/Ncomms3990 |
0.802 |
|
2013 |
Cannon JL, Asperti-Boursin F, Letendre KA, Brown IK, Korzekwa KE, Blaine KM, Oruganti SR, Sperling AI, Moses ME. PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod. Plos One. 8: e78940. PMID 24250818 DOI: 10.1371/Journal.Pone.0078940 |
0.54 |
|
2013 |
Williams JW, Yau D, Sethakorn N, Kach J, Reed EB, Moore TV, Cannon J, Jin X, Xing H, Muslin AJ, Sperling AI, Dulin NO. RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L693-701. PMID 24077945 DOI: 10.1152/Ajplung.00214.2013 |
0.818 |
|
2013 |
Wu Q, Gardiner GJ, Berry E, Wagner SR, Lu T, Clay BS, Moore TV, Ferreira CM, Williams JW, Luster AD, Medoff BD, Cannon JL, Sperling AI, Shilling RA. ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection. Plos One. 8: e72955. PMID 23967339 DOI: 10.1371/Journal.Pone.0072955 |
0.817 |
|
2013 |
Tjota MY, Williams JW, Lu T, Clay BS, Byrd T, Hrusch CL, Decker DC, de Araujo CA, Bryce PJ, Sperling AI. IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling. The Journal of Clinical Investigation. 123: 2287-97. PMID 23585480 DOI: 10.1172/Jci63802 |
0.809 |
|
2013 |
Kach J, Sandbo N, Sethakorn N, Williams J, Reed EB, La J, Tian X, Brain SD, Rajendran K, Krishnan R, Sperling AI, Birukov K, Dulin NO. Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin American Journal of Physiology - Lung Cellular and Molecular Physiology. 304: L757-L764. PMID 23585227 DOI: 10.1152/Ajplung.00262.2012 |
0.301 |
|
2013 |
Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C. Maternal asthma and microRNA regulation of soluble HLA-G in the airway. The Journal of Allergy and Clinical Immunology. 131: 1496-503. PMID 23534973 DOI: 10.1016/J.Jaci.2013.01.037 |
0.477 |
|
2013 |
Patterson KC, Franek BS, Müller-Quernheim J, Sperling AI, Sweiss NJ, Niewold TB. Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease. Cytokine. 61: 906-11. PMID 23384655 DOI: 10.1016/J.Cyto.2012.12.016 |
0.302 |
|
2013 |
Shilling RA, Williams JW, Perera J, Berry E, Wu Q, Cummings OW, Sperling AI, Huang H. Autoreactive T and B cells induce the development of bronchus-associated lymphoid tissue in the lung. American Journal of Respiratory Cell and Molecular Biology. 48: 406-14. PMID 23371062 DOI: 10.1165/Rcmb.2012-0065Oc |
0.496 |
|
2012 |
Williams JW, Tjota MY, Sperling AI. The contribution of allergen-specific IgG to the development of th2-mediated airway inflammation. Journal of Allergy. 2012: 236075. PMID 23150737 DOI: 10.1155/2012/236075 |
0.452 |
|
2012 |
Patterson KC, Hogarth K, Husain AN, Sperling AI, Niewold TB. The clinical and immunologic features of pulmonary fibrosis in sarcoidosis. Translational Research : the Journal of Laboratory and Clinical Medicine. 160: 321-31. PMID 22683422 DOI: 10.1016/J.Trsl.2012.03.005 |
0.343 |
|
2012 |
Edelblum KL, Shen L, Weber CR, Marchiando AM, Clay BS, Wang Y, Prinz I, Malissen B, Sperling AI, Turner JR. Dynamic migration of γδ intraepithelial lymphocytes requires occludin. Proceedings of the National Academy of Sciences of the United States of America. 109: 7097-102. PMID 22511722 DOI: 10.1073/Pnas.1112519109 |
0.797 |
|
2012 |
Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Poli? B, ... ... Sperling AI, et al. NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nature Medicine. 18: 422-8. PMID 22366950 DOI: 10.1038/Nm.2683 |
0.817 |
|
2011 |
Moore TV, Clay BS, Cannon JL, Histed A, Shilling RA, Sperling AI. Inducible costimulator controls migration of T cells to the lungs via down-regulation of CCR7 and CD62L American Journal of Respiratory Cell and Molecular Biology. 45: 843-850. PMID 21421907 DOI: 10.1165/Rcmb.2010-0466Oc |
0.85 |
|
2011 |
Moore TV, Clay BS, Ferreira CM, Williams JW, Rogozinska M, Cannon JL, Shilling RA, Marzo AL, Sperling AI. Protective effector memory CD4 T cells depend on ICOS for survival. Plos One. 6: e16529. PMID 21364749 DOI: 10.1371/Journal.Pone.0016529 |
0.842 |
|
2011 |
Cannon JL, Mody PD, Blaine KM, Chen EJ, Nelson AD, Sayles LJ, Moore TV, Clay BS, Dulin NO, Shilling RA, Burkhardt JK, Sperling AI. CD43 interaction with ezrin-radixin-moesin (ERM) proteins regulates T-cell trafficking and CD43 phosphorylation. Molecular Biology of the Cell. 22: 954-63. PMID 21289089 DOI: 10.1091/Mbc.E10-07-0586 |
0.818 |
|
2011 |
Edelblum KL, Shen L, Marchiando AM, Wang Y, Sperling AI, Turner JR. Occludin Regulates γδ Intraepithelial Lymphocyte Migration In Vivo Gastroenterology. 140: S-132. DOI: 10.1016/S0016-5085(11)60540-4 |
0.363 |
|
2010 |
Shaffer MH, Huang Y, Corbo E, Wu GF, Velez M, Choi JK, Saotome I, Cannon JL, McClatchey AI, Sperling AI, Maltzman JS, Oliver PM, Bhandoola A, Laufer TM, Burkhardt JK. Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice. Plos One. 5: e12404. PMID 20806059 DOI: 10.1371/Journal.Pone.0012404 |
0.447 |
|
2010 |
Bhorade SM, Chen H, Molinero L, Liao C, Garrity ER, Vigneswaran WT, Shilling R, Sperling A, Chong A, Alegre ML. Decreased percentage of CD4+FoxP3+ cells in bronchoalveolar lavage from lung transplant recipients correlates with development of bronchiolitis obliterans syndrome. Transplantation. 90: 540-6. PMID 20628341 DOI: 10.1097/Tp.0B013E3181E8Dabe |
0.596 |
|
2010 |
Tong J, Clay BS, Ferreira CM, Bandukwala HS, Moore TV, Blaine KM, Williams JW, Hoffman LM, Hamann KJ, Shilling RA, Weinstock JV, Sperling AI. Fas ligand expression on T cells is sufficient to prevent prolonged airway inflammation in a murine model of asthma. American Journal of Respiratory Cell and Molecular Biology. 43: 342-8. PMID 19855087 DOI: 10.1165/Rcmb.2008-0454Oc |
0.822 |
|
2010 |
Edelblum KL, Marchiando AM, Shen L, Wang Y, Sperling AI, Turner JR. 578 Tight Junction Protein Expression by γδ IELs Regulates Gastrointestinal Lymphocyte-Epithelial Interactions Gastroenterology. 138: S-82. DOI: 10.1016/S0016-5085(10)60373-3 |
0.305 |
|
2009 |
Zhao Y, Tong J, He D, Pendyala S, Evgeny B, Chun J, Sperling AI, Natarajan V. Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma. Respiratory Research. 10: 114. PMID 19930563 DOI: 10.1186/1465-9921-10-114 |
0.368 |
|
2009 |
Clay BS, Shilling RA, Bandukwala HS, Moore TV, Cannon JL, Welcher AA, Weinstock JV, Sperling AI. Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells. Plos One. 4: e7525. PMID 19888475 DOI: 10.1371/Journal.Pone.0007525 |
0.822 |
|
2009 |
Shilling RA, Clay BS, Tesciuba AG, Berry EL, Lu T, Moore TV, Bandukwala HS, Tong J, Weinstock JV, Flavell RA, Horan T, Yoshinaga SK, Welcher AA, Cannon JL, Sperling AI. CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo. Cellular Immunology. 259: 177-84. PMID 19646680 DOI: 10.1016/J.Cellimm.2009.06.013 |
0.798 |
|
2008 |
Tesciuba AG, Shilling RA, Agarwal MD, Bandukwala HS, Clay BS, Moore TV, Weinstock JV, Welcher AA, Sperling AI. ICOS costimulation expands Th2 immunity by augmenting migration of lymphocytes to draining lymph nodes. Journal of Immunology (Baltimore, Md. : 1950). 181: 1019-24. PMID 18606653 DOI: 10.4049/Jimmunol.181.2.1019 |
0.786 |
|
2008 |
Cannon JL, Collins A, Mody PD, Balachandran D, Henriksen KJ, Smith CE, Tong J, Clay BS, Miller SD, Sperling AI. CD43 regulates Th2 differentiation and inflammation. Journal of Immunology (Baltimore, Md. : 1950). 180: 7385-93. PMID 18490738 DOI: 10.4049/Jimmunol.180.11.7385 |
0.849 |
|
2007 |
Clay BS, Sperling AI. T-cell costimulation blockade in immunologic diseases: role of CD28 family members. Expert Review of Clinical Immunology. 3: 383-93. PMID 20477681 DOI: 10.1586/1744666X.3.3.383 |
0.826 |
|
2007 |
Bandukwala HS, Clay BS, Tong J, Mody PD, Cannon JL, Shilling RA, Verbeek JS, Weinstock JV, Solway J, Sperling AI. Signaling through Fc gamma RIII is required for optimal T helper type (Th)2 responses and Th2-mediated airway inflammation. The Journal of Experimental Medicine. 204: 1875-89. PMID 17664287 DOI: 10.1084/Jem.20061134 |
0.803 |
|
2007 |
Mody PD, Cannon JL, Bandukwala HS, Blaine KM, Schilling AB, Swier K, Sperling AI. Signaling through CD43 regulates CD4 T-cell trafficking. Blood. 110: 2974-82. PMID 17638845 DOI: 10.1182/Blood-2007-01-065276 |
0.837 |
|
2007 |
Clay BS, Sperling AI. T-cell costimulation blockade in immunologic diseases: Role of CD28 family members Expert Review of Clinical Immunology. 3: 383-393. DOI: 10.1586/1744666X.3.3.383 |
0.817 |
|
2006 |
Shilling RA, Bandukwala HS, Sperling AI. Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? Clinical Immunology (Orlando, Fla.). 121: 13-8. PMID 16790364 DOI: 10.1016/J.Clim.2006.04.574 |
0.82 |
|
2006 |
Tong J, Bandulwala HS, Clay BS, Anders RA, Shilling RA, Balachandran DD, Chen B, Weinstock JV, Solway J, Hamann KJ, Sperling AI. Fas-positive T cells regulate the resolution of airway inflammation in a murine model of asthma. The Journal of Experimental Medicine. 203: 1173-84. PMID 16618792 DOI: 10.1084/Jem.20051680 |
0.822 |
|
2006 |
Cannon J, Mody P, Sperling A. Su.110. Pka and Pkd Phosphorylation of Cd43 in T-Cells Clinical Immunology. 119: S197. DOI: 10.1016/J.Clim.2006.04.537 |
0.831 |
|
2005 |
Blair C, Naclerio RM, Yu X, Thompson K, Sperling A. Role of type 1 T helper cells in the resolution of acute Streptococcus pneumoniae sinusitis: a mouse model. The Journal of Infectious Diseases. 192: 1237-44. PMID 16136467 DOI: 10.1086/444544 |
0.456 |
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2005 |
Shilling RA, Pinto JM, Decker DC, Schneider DH, Bandukwala HS, Schneider JR, Camoretti-Mercado B, Ober C, Sperling AI. Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production. Journal of Immunology (Baltimore, Md. : 1950). 175: 2061-5. PMID 16081771 DOI: 10.4049/Jimmunol.175.4.2061 |
0.782 |
|
2005 |
Sperling AI, Bluestone JA. Non-classical MHC molecules: the first line of defence? Current Biology : Cb. 3: 294-6. PMID 15335753 DOI: 10.1016/0960-9822(93)90183-O |
0.428 |
|
2004 |
Yu X, Sperling A, Blair C, Thompson K, Naclerio R. Antigen stimulation of TH2 cells augments acute bacterial sinusitis in mice. The Journal of Allergy and Clinical Immunology. 114: 328-34. PMID 15316511 DOI: 10.1016/J.Jaci.2004.04.051 |
0.434 |
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2004 |
Tong J, Allenspach EJ, Takahashi SM, Mody PD, Park C, Burkhardt JK, Sperling AI. CD43 regulation of T cell activation is not through steric inhibition of T cell-APC interactions but through an intracellular mechanism. The Journal of Experimental Medicine. 199: 1277-83. PMID 15117976 DOI: 10.1084/Jem.20021602 |
0.838 |
|
2003 |
Ford ML, Onami TM, Sperling AI, Ahmed R, Evavold BD. CD43 modulates severity and onset of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 171: 6527-33. PMID 14662853 DOI: 10.4049/Jimmunol.171.12.6527 |
0.564 |
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2003 |
Kang HS, Blink SE, Chin RK, Lee Y, Kim O, Weinstock J, Waldschmidt T, Conrad D, Chen B, Solway J, Sperling AI, Fu YX. Lymphotoxin is required for maintaining physiological levels of serum IgE that minimizes Th1-mediated airway inflammation. The Journal of Experimental Medicine. 198: 1643-52. PMID 14638845 DOI: 10.1084/Jem.20021784 |
0.483 |
|
2003 |
Dorscheid DR, Low E, Conforti A, Shifrin S, Sperling AI, White SR. Corticosteroid-induced apoptosis in mouse airway epithelium: effect in normal airways and after allergen-induced airway inflammation. The Journal of Allergy and Clinical Immunology. 111: 360-6. PMID 12589357 DOI: 10.1067/Mai.2003.117 |
0.336 |
|
2003 |
Blair C, Yu X, Thompson K, Baroody F, Naclerio R, Sperling A. Resolution of acute sinusitis requires the T-cell adaptive immune response Journal of Allergy and Clinical Immunology. 111: S124. DOI: 10.1016/S0091-6749(03)80378-0 |
0.444 |
|
2002 |
Cullinan P, Sperling AI, Burkhardt JK. The distal pole complex: a novel membrane domain distal to the immunological synapse. Immunological Reviews. 189: 111-22. PMID 12445269 DOI: 10.1034/J.1600-065X.2002.18910.X |
0.52 |
|
2001 |
Allenspach EJ, Cullinan P, Tong J, Tang Q, Tesciuba AG, Cannon JL, Takahashi SM, Morgan R, Burkhardt JK, Sperling AI. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse Immunity. 15: 739-750. PMID 11728336 DOI: 10.1016/S1074-7613(01)00224-2 |
0.817 |
|
2001 |
Tesciuba AG, Subudhi S, Rother RP, Faas SJ, Frantz AM, Elliot D, Weinstock J, Matis LA, Bluestone JA, Sperling AI. Inducible costimulator regulates Th2-mediated inflammation, but not Th2 differentiation, in a model of allergic airway disease. Journal of Immunology (Baltimore, Md. : 1950). 167: 1996-2003. PMID 11489981 DOI: 10.4049/Jimmunol.167.4.1996 |
0.824 |
|
2001 |
Sperling AI, Bluestone JA. ICOS costimulation: It's not just for TH2 cells anymore. Nature Immunology. 2: 573-4. PMID 11429535 DOI: 10.1038/89709 |
0.573 |
|
2000 |
Shiels H, Li X, Schumacker PT, Maltepe E, Padrid PA, Sperling A, Thompson CB, Lindsten T. TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs American Journal of Pathology. 157: 679-688. PMID 10934170 DOI: 10.1016/S0002-9440(10)64578-6 |
0.349 |
|
2000 |
Douglas IS, Leff AR, Sperling AI. CD4+ T cell and eosinophil adhesion is mediated by specific ICAM-3 ligation and results in eosinophil activation. Journal of Immunology (Baltimore, Md. : 1950). 164: 3385-91. PMID 10706734 DOI: 10.4049/Jimmunol.164.6.3385 |
0.591 |
|
1999 |
Rajagopal K, Sommers CL, Decker DC, Mitchell EO, Korthauer U, Sperling AI, Kozak CA, Love PE, Bluestone JA. RIBP, a novel Rlk/Txk- and itk-binding adaptor protein that regulates T cell activation. The Journal of Experimental Medicine. 190: 1657-68. PMID 10587356 DOI: 10.1084/Jem.190.11.1657 |
0.769 |
|
1998 |
Hamann KJ, Dorscheid DR, Ko FD, Conforti AE, Sperling AI, Rabe KF, White SR. Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium. American Journal of Respiratory Cell and Molecular Biology. 19: 537-42. PMID 9761749 DOI: 10.1165/Ajrcmb.19.4.3100 |
0.408 |
|
1998 |
Padrid PA, Mathur M, Li X, Herrmann K, Qin Y, Cattamanchi A, Weinstock J, Elliott D, Sperling AI, Bluestone JA. CTLA4Ig inhibits airway eosinophilia and hyperresponsiveness by regulating the development of Th1/Th2 subsets in a murine model of asthma. American Journal of Respiratory Cell and Molecular Biology. 18: 453-62. PMID 9533932 DOI: 10.1165/Ajrcmb.18.4.3055 |
0.693 |
|
1997 |
Sperling AI, Bluestone JA. The complexities of T-cell co-stimulation: CD28 and beyond. Immunological Reviews. 153: 155-82. PMID 9010723 DOI: 10.1111/J.1600-065X.1996.Tb00924.X |
0.642 |
|
1996 |
Bluestone JA, Khattri R, Sciammas R, Sperling AI. TCR gamma delta cells: a specialized T-cell subset in the immune system. Annual Review of Cell and Developmental Biology. 11: 307-53. PMID 8689560 DOI: 10.1146/Annurev.Cb.11.110195.001515 |
0.648 |
|
1995 |
Sperling AI, Green JM, Mosley RL, Smith PL, DiPaolo RJ, Klein JR, Bluestone JA, Thompson CB. CD43 is a murine T cell costimulatory receptor that functions independently of CD28. The Journal of Experimental Medicine. 182: 139-46. PMID 7790813 DOI: 10.1084/Jem.182.1.139 |
0.685 |
|
1995 |
Sciammas R, Tatsumi Y, Sperling AI, Arunan K, Bluestone JA. TCR gamma delta cells: mysterious cells of the immune system. Immunologic Research. 13: 268-79. PMID 7616054 DOI: 10.1007/Bf02935618 |
0.583 |
|
1995 |
Green JM, Noel PJ, Sperling AI, Walunas TL, Gray GS, Bluestone JA, Thompson CB. Absence of B7-dependent responses in CD28-deficient mice. Immunity. 1: 501-8. PMID 7534617 DOI: 10.1016/1074-7613(94)90092-2 |
0.687 |
|
1993 |
Qian D, Sperling AI, Lancki DW, Tatsumi Y, Barrett TA, Bluestone JA, Fitch FW. The gamma chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 11875-9. PMID 8265641 DOI: 10.1073/Pnas.90.24.11875 |
0.627 |
|
1991 |
Bluestone JA, Cron RQ, Barrett TA, Houlden B, Sperling AI, Dent A, Hedrick S, Rellahan B, Matis LA. Repertoire development and ligand specificity of murine TCR gamma delta cells. Immunological Reviews. 120: 5-33. PMID 1650760 DOI: 10.1111/J.1600-065X.1991.Tb00585.X |
0.557 |
|
1989 |
Sperling AI, Wortis HH. CD4-, CD8- γ/δ cells from normal mice respond to a syngeneic B cell lymphoma and can induce its differentiation International Immunology. 1: 434-441. PMID 2577376 DOI: 10.1093/Intimm/1.4.434 |
0.717 |
|
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