Year |
Citation |
Score |
2023 |
Denakpo E, Naas T, Iorga BI. An updated patent review of metallo-β-lactamase inhibitors (2020-2023). Expert Opinion On Therapeutic Patents. 33: 523-538. PMID 37737836 DOI: 10.1080/13543776.2023.2262763 |
0.498 |
|
2023 |
Gaillot S, Oueslati S, Vuillemenot JB, Bour M, Iorga BI, Triponney P, Plésiat P, Bonnin RA, Naas T, Jeannot K, Potron A. Genomic characterization of an NDM-9-producing clinical isolate and role of Glu152Lys substitution in the enhanced cefiderocol hydrolysis of NDM-9. Frontiers in Microbiology. 14: 1253160. PMID 37700870 DOI: 10.3389/fmicb.2023.1253160 |
0.477 |
|
2023 |
Dabos L, Raczynska JE, Bogaerts P, Zavala A, Girlich D, Bonnin RA, Dortet L, Peyrat A, Retailleau P, Iorga BI, Jaskólski M, Glupczynski Y, Naas T. Structural and Biochemical Features of OXA-517: a Carbapenem and Expanded-Spectrum Cephalosporin Hydrolyzing OXA-48 Variant. Antimicrobial Agents and Chemotherapy. e0109522. PMID 36648230 DOI: 10.1128/aac.01095-22 |
0.799 |
|
2022 |
Dahdouh E, Allander L, Falgenhauer L, Iorga BI, Lorenzetti S, Marcos-Alcalde Í, Martin NI, Martínez-Martínez L, Mingorance J, Naas T, Rubin JE, Spyrakis F, Tängdén T, Gómez-Puertas P. Computational Modeling and Design of New Inhibitors of Carbapenemases: A Discussion from the EPIC Alliance Network. International Journal of Molecular Sciences. 23. PMID 36077146 DOI: 10.3390/ijms23179746 |
0.419 |
|
2022 |
Muntean MM, Muntean AA, Guerin F, Cattoir V, Creton E, Cotellon G, Oueslati S, Popa MI, Girlich D, Iorga BI, Bonnin RA, Naas T. Optimization of the rapid carbapenem inactivation method for use with AmpC hyperproducers-authors' response. The Journal of Antimicrobial Chemotherapy. PMID 35199171 DOI: 10.1093/jac/dkac058 |
0.37 |
|
2021 |
Jousset AB, Oueslati S, Emeraud C, Bonnin RA, Dortet L, Iorga BI, Naas T. KPC-39-Mediated Resistance to Ceftazidime-Avibactam in a Klebsiella pneumoniae ST307 Clinical Isolate. Antimicrobial Agents and Chemotherapy. 65: e0116021. PMID 34606331 DOI: 10.1128/AAC.01160-21 |
0.438 |
|
2021 |
de Barsy M, Mercuri PS, Oueslati S, Elisée E, Huang TD, Sacré P, Iorga BI, Naas T, Galleni M, Bogaerts P. Detection and characterization of VIM-52, a new variant of VIM-1 from clinical isolate. Antimicrobial Agents and Chemotherapy. AAC0266020. PMID 34370584 DOI: 10.1128/AAC.02660-20 |
0.783 |
|
2021 |
Muntean MM, Muntean AA, Guerin F, Cattoir V, Creton E, Cotellon G, Oueslati S, Popa MI, Girlich D, Iorga BI, Bonnin RA, Naas T. Optimization of the rapid carbapenem inactivation method for use with AmpC hyperproducers. The Journal of Antimicrobial Chemotherapy. PMID 34143889 DOI: 10.1093/jac/dkab170 |
0.38 |
|
2021 |
Rima M, Emeraud C, Bonnin RA, Gonzalez C, Dortet L, Iorga BI, Oueslati S, Naas T. Biochemical characterization of OXA-244, an emerging OXA-48 variant with reduced β-lactam hydrolytic activity. The Journal of Antimicrobial Chemotherapy. PMID 33993262 DOI: 10.1093/jac/dkab142 |
0.466 |
|
2021 |
Romero E, Oueslati S, Benchekroun M, D'Hollander ACA, Ventre S, Vijayakumar K, Minard C, Exilie C, Tlili L, Retailleau P, Zavala A, Elisée E, Selwa E, Nguyen LA, Pruvost A, ... ... Iorga BI, et al. Azetidinimines as a novel series of non-covalent broad-spectrum inhibitors of β-lactamases with submicromolar activities against carbapenemases KPC-2 (class A), NDM-1 (class B) and OXA-48 (class D). European Journal of Medicinal Chemistry. 219: 113418. PMID 33862516 DOI: 10.1016/j.ejmech.2021.113418 |
0.764 |
|
2021 |
Çekin ZK, Dabos L, Malkoçoğlu G, Fortineau N, Bayraktar B, Iorga BI, Naas T, Aktaş E. Carbapenemase -producing Pseudomonas aeruginosa isolates from Turkey: first report of P. aeruginosa high-risk clones with VIM-5- and IMP-7-type carbapenemases in a tertiary hospital. Diagnostic Microbiology and Infectious Disease. 99: 115174. PMID 32980808 DOI: 10.1016/J.Diagmicrobio.2020.115174 |
0.486 |
|
2020 |
Rivière G, Oueslati S, Gayral M, Créchet JB, Nhiri N, Jacquet E, Cintrat JC, Giraud F, van Heijenoort C, Lescop E, Pethe S, Iorga BI, Naas T, Guittet E, Morellet N. NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-Lactamase-1 and on the Binding with Flavonols as Inhibitors. Acs Omega. 5: 10466-10480. PMID 32426604 DOI: 10.1021/acsomega.0c00590 |
0.505 |
|
2020 |
Dabos L, Zavala A, Bonnin RA, Beckstein O, Retailleau P, Iorga BI, Naas T. Substrate Specificity of OXA-48 after β5-β6 Loop Replacement. Acs Infectious Diseases. 6: 1032-1043. PMID 32156115 DOI: 10.1021/Acsinfecdis.9B00452 |
0.796 |
|
2020 |
Oueslati S, Retailleau P, Marchini L, Berthault C, Dortet L, Bonnin RA, Iorga BI, Naas T. Role of Arginine 214 in the Substrate Specificity of OXA-48. Antimicrobial Agents and Chemotherapy. 64. PMID 32071047 DOI: 10.1128/Aac.02329-19 |
0.46 |
|
2019 |
Oueslati S, Retailleau P, Marchini L, Dortet L, Bonnin RA, Iorga BI, Naas T. Biochemical and Structural Characterization of OXA-405, an OXA-48 Variant with Extended-Spectrum β-Lactamase Activity. Microorganisms. 8. PMID 31877796 DOI: 10.3390/microorganisms8010024 |
0.527 |
|
2019 |
Oueslati S, Tlili L, Exilie C, Bernabeu S, Iorga B, Bonnin RA, Dortet L, Naas T. Different phenotypic expression of KPC β-lactamase variants and challenges in their detection. The Journal of Antimicrobial Chemotherapy. PMID 31848599 DOI: 10.1093/Jac/Dkz508 |
0.505 |
|
2019 |
Dabos L, Rodriguez CH, Nastro M, Dortet L, Bonnin R, Famiglietti A, Iorga BI, Vay C, Naas T. LMB-1 producing Citrobacter freundii from Argentina, a novel player in the field of MBLs. International Journal of Antimicrobial Agents. PMID 31785341 DOI: 10.1016/J.Ijantimicag.2019.11.014 |
0.488 |
|
2019 |
Elisée E, Gapsys V, Mele N, Chaput L, Selwa E, de Groot BL, Iorga BI. Performance evaluation of molecular docking and free energy calculations protocols using the D3R Grand Challenge 4 dataset. Journal of Computer-Aided Molecular Design. 33: 1031-1043. PMID 31677003 DOI: 10.1007/S10822-019-00232-W |
0.747 |
|
2019 |
Oueslati S, Iorga BI, Tlili L, Exilie C, Zavala A, Dortet L, Jousset AB, Bernabeu S, Bonnin RA, Naas T. Unravelling ceftazidime/avibactam resistance of KPC-28, a KPC-2 variant lacking carbapenemase activity. The Journal of Antimicrobial Chemotherapy. 74: 2239-2246. PMID 31127297 DOI: 10.1093/Jac/Dkz209 |
0.772 |
|
2019 |
Zavala A, Retailleau P, Elisée E, Iorga BI, Naas T. Genetic, Biochemical, and Structural Characterization of CMY-136 β-Lactamase, a Peculiar CMY-2 Variant. Acs Infectious Diseases. 5: 528-538. PMID 30788955 DOI: 10.1021/Acsinfecdis.8B00240 |
0.775 |
|
2019 |
Chaput L, Selwa E, Elisée E, Iorga BI. Blinded evaluation of cathepsin S inhibitors from the D3RGC3 dataset using molecular docking and free energy calculations. Journal of Computer-Aided Molecular Design. 33: 93-103. PMID 30206740 DOI: 10.1007/S10822-018-0161-7 |
0.777 |
|
2018 |
Mounkoro P, Michel T, Benhachemi R, Surpateanu G, Iorga BI, Fisher N, Meunier B. Mitochondrial complex III Q -site inhibitor resistance mutations found in laboratory selected mutants and field isolates. Pest Management Science. PMID 30426681 DOI: 10.1002/Ps.5264 |
0.664 |
|
2018 |
Selwa E, Kenney IM, Beckstein O, Iorga BI. SAMPL6: calculation of macroscopic pK values from ab initio quantum mechanical free energies. Journal of Computer-Aided Molecular Design. PMID 30084080 DOI: 10.1007/S10822-018-0138-6 |
0.746 |
|
2018 |
Dabos L, Jousset AB, Bonnin RA, Fortineau N, Zavala A, Retailleau P, Iorga BI, Naas T. Genetic and Biochemical Characterization of OXA-535, a Distantly Related OXA-48-Like β-Lactamase. Antimicrobial Agents and Chemotherapy. 62. PMID 30082287 DOI: 10.1128/Aac.01198-18 |
0.776 |
|
2018 |
Nguyen TL, Nokin MJ, Egorov M, Tomé M, Bodineau C, Di Primo C, Minder L, Wdzieczak-Bakala J, Garcia-Alvarez MC, Bignon J, Thoison O, Delpech B, Surpateanu G, Frapart YM, Peyrot F, ... ... Iorga BI, et al. mTOR inhibition via displacement of phosphatidic acid induces enhanced cytotoxicity specifically in cancer cells. Cancer Research. PMID 30054335 DOI: 10.1158/0008-5472.Can-18-0232 |
0.652 |
|
2018 |
Dabos L, Bogaerts P, Bonnin RA, Zavala A, Sacré P, Iorga BI, Huang DT, Glupczynski Y, Naas T. Genetic and Biochemical characterization of OXA-519, a novel OXA-48-like β-lactamase. Antimicrobial Agents and Chemotherapy. PMID 29866857 DOI: 10.1128/Aac.00469-18 |
0.785 |
|
2018 |
Selwa E, Elisée E, Zavala A, Iorga BI. Blinded evaluation of farnesoid X receptor (FXR) ligands binding using molecular docking and free energy calculations. Journal of Computer-Aided Molecular Design. 32: 273-286. PMID 28865056 DOI: 10.1007/S10822-017-0054-1 |
0.758 |
|
2017 |
Naas T, Oueslati S, Bonnin RA, Dabos ML, Zavala A, Dortet L, Retailleau P, Iorga BI. Beta-lactamase database (BLDB) - structure and function. Journal of Enzyme Inhibition and Medicinal Chemistry. 32: 917-919. PMID 28719998 DOI: 10.1080/14756366.2017.1344235 |
0.737 |
|
2017 |
Dortet L, Girlich D, Virlouvet AL, Poirel L, Nordmann P, Iorga BI, Naas T. Characterization of BRP, the Bleomycin Resistance Protein Associated with the Carbapenemase NDM. Antimicrobial Agents and Chemotherapy. 61. PMID 28069656 DOI: 10.1128/Aac.02413-16 |
0.457 |
|
2016 |
Selwa E, Martiny VY, Iorga BI. Molecular docking performance evaluated on the D3R Grand Challenge 2015 drug-like ligand datasets. Journal of Computer-Aided Molecular Design. 30: 829-839. PMID 27699554 DOI: 10.1007/S10822-016-9983-3 |
0.761 |
|
2016 |
Naas T, Dortet L, Iorga BI. Structural and Functional Aspects of Class A Carbapenemases. Current Drug Targets. 17: 1006-28. PMID 26960341 DOI: 10.2174/1389450117666160310144501 |
0.515 |
|
2016 |
Martiny VY, Martz F, Selwa E, Iorga BI. Blind Pose Prediction, Scoring, and Affinity Ranking of the CSAR 2014 Dataset. Journal of Chemical Information and Modeling. 56: 996-1003. PMID 26391724 DOI: 10.1021/Acs.Jcim.5B00337 |
0.777 |
|
2015 |
Pous J, Courant T, Bernadat G, Iorga BI, Blanchard F, Masson G. Regio-, Diastereo-, and Enantioselective Nitroso-Diels-Alder Reaction of 1,3-Diene-1-carbamates Catalyzed by Chiral Phosphoric Acids. Journal of the American Chemical Society. 137: 11950-3. PMID 26355670 DOI: 10.1021/Jacs.5B08515 |
0.614 |
|
2015 |
List B, Höfler D, Pous J, Courant T, Bernadat G, Iorga BI, Blanchard F, Masson G. Phosphoric Acid-Catalyzed Asymmetric Nitroso-Diels–Alder Reaction Synfacts. 11: 1212-1212. DOI: 10.1055/S-0035-1560719 |
0.6 |
|
2014 |
Desrat S, Pujals A, Colas C, Dardenne J, Gény C, Favre L, Dumontet V, Iorga BI, Litaudon M, Raphaël M, Wiels J, Roussi F. Pro-apoptotic meiogynin A derivatives that target Bcl-xL and Mcl-1. Bioorganic & Medicinal Chemistry Letters. 24: 5086-8. PMID 25266781 DOI: 10.1016/J.Bmcl.2014.09.004 |
0.645 |
|
2014 |
Colas C, Iorga BI. Virtual screening of the SAMPL4 blinded HIV integrase inhibitors dataset. Journal of Computer-Aided Molecular Design. 28: 455-62. PMID 24458507 DOI: 10.1007/S10822-014-9707-5 |
0.669 |
|
2014 |
de Miguel L, Noiray M, Surpateanu G, Iorga BI, Ponchel G. Poly(γ-benzyl-L-glutamate)-PEG-alendronate multivalent nanoparticles for bone targeting. International Journal of Pharmaceutics. 460: 73-82. PMID 24211357 DOI: 10.1016/J.Ijpharm.2013.10.048 |
0.632 |
|
2014 |
Desrat S, Remeur C, Gény C, Rivière G, Colas C, Dumontet V, Birlirakis N, Iorga BI, Roussi F. From meiogynin A to the synthesis of dual inhibitors of Bcl-xL and Mcl-1 anti-apoptotic proteins Chemical Communications. 50: 8593. DOI: 10.1039/C4Cc01830C |
0.656 |
|
2014 |
Nicolas C, Porceddu M, Buron N, Wang Z, Colas C, Iorga B, Ambroise Y, Vandecasteele G, Fischmeister R, Borgne-Sanchez A, Brenner C. 0256: A screening strategy to identify modulators of the mitochondrial ADP/ATP translocase (ANT) for cardioprotection Archives of Cardiovascular Diseases Supplements. 6: 58. DOI: 10.1016/S1878-6480(14)71422-3 |
0.676 |
|
2013 |
Bernadat G, Supuran CT, Iorga BI. Carbonic anhydrase binding site parameterization in OPLS-AA force field. Bioorganic & Medicinal Chemistry. 21: 1427-30. PMID 23182217 DOI: 10.1016/J.Bmc.2012.10.040 |
0.607 |
|
2012 |
Nguyen TB, Lozach O, Surpateanu G, Wang Q, Retailleau P, Iorga BI, Meijer L, Guéritte F. Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. Journal of Medicinal Chemistry. 55: 2811-9. PMID 22352892 DOI: 10.1021/Jm201727W |
0.676 |
|
2012 |
Surpateanu G, Iorga BI. Evaluation of docking performance in a blinded virtual screening of fragment-like trypsin inhibitors. Journal of Computer-Aided Molecular Design. 26: 595-601. PMID 22180049 DOI: 10.1007/S10822-011-9526-X |
0.671 |
|
2012 |
Surpateanu G, Soulé JF, Beau JM, Norsikian S, Iorga BI. Conformational study of glycal-type neuraminidase inhibitors Journal of Carbohydrate Chemistry. 31: 114-129. DOI: 10.1080/07328303.2011.636161 |
0.682 |
|
2012 |
Dardenne J, Pujals A, Colas C, Birlirakis N, Wiels J, Dumontet V, Geny C, Iorga B, Guéritte F, Roussi F. Pharmacomodulation of Meiogynin A, a dimeric sesquiterpenoid inhibiting BCL-XL and BAK interaction Planta Medica. 78. DOI: 10.1055/S-0032-1320396 |
0.646 |
|
2012 |
Amara N, Vijayan R, Biggin PC, Iorga BI. Ionontropic Glutamate Receptors: Insight into the Mechanism of Desensitization and Deactivation using Molecular Dynamics Simulations Biophysical Journal. 102: 114a. DOI: 10.1016/J.Bpj.2011.11.642 |
0.755 |
|
2011 |
Rouleau J, Iorga BI, Guillou C. New potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid β aggregation European Journal of Medicinal Chemistry. 46: 2193-2205. PMID 21435752 DOI: 10.1016/J.Ejmech.2011.02.073 |
0.612 |
|
2011 |
Aráoz R, Chabaud L, Guillou C, Molgó J, Iorga BI. Spiroimine Toxins in Complex with Nicotinic Acetylcholine Receptors: Structure and Dynamics Biophysical Journal. 100: 347a. DOI: 10.1016/J.Bpj.2010.12.2093 |
0.613 |
|
2009 |
Varin M, Barré E, Iorga B, Guillou C. Synthesis of (±)-Codeine Synfacts. 2009: 126-126. DOI: 10.1055/S-0028-1087602 |
0.746 |
|
2008 |
Varin M, Barré E, Iorga B, Guillou C. Diastereoselective total synthesis of (+/-)-codeine. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 6606-8. PMID 18561354 DOI: 10.1002/Chem.200800744 |
0.762 |
|
2007 |
Varin M, Chiaroni A, Lallemand JY, Iorga B, Guillou C. A new access to dihydrotropones through ring expansion of spirocyclohexadienones: synthesis and mechanism. The Journal of Organic Chemistry. 72: 6421-6. PMID 17655358 DOI: 10.1021/Jo070594P |
0.776 |
|
2006 |
Iorga B, Herlem D, Barré E, Guillou C. Acetylcholine nicotinic receptors: finding the putative binding site of allosteric modulators using the "blind docking" approach. Journal of Molecular Modeling. 12: 366-72. PMID 16372175 DOI: 10.1007/S00894-005-0057-Z |
0.618 |
|
2005 |
Iorga B, Campagne J. Ethyl Propiolate: A Simple and Convenient Peptide Coupling Reagent. Cheminform. 36. DOI: 10.1055/S-2004-829553 |
0.572 |
|
2003 |
Scozzafava A, Iorga B, Supuran CT. Carbonic anhydrase activators: synthesis of high affinity isozymes I, II and IV activators, derivatives of 4-(4-tosylureido-amino acyl)ethyl-1H-imidazole (histamine derivatives). Journal of Enzyme Inhibition. 15: 139-61. PMID 10938540 DOI: 10.1080/14756360009030347 |
0.315 |
|
2001 |
Iorga B, Savignac P. Controlled Reactivity of Phosphonates by Temporary Silicon Connection Synlett. 2001: 0447-0457. DOI: 10.1055/S-2001-12309 |
0.523 |
|
2001 |
Iorga B, Savignac P. Controlled monohalogenation of phosphonates Journal of Organometallic Chemistry. 624: 203-207. DOI: 10.1016/S0022-328X(00)00889-5 |
0.571 |
|
2000 |
Clare BW, Scozzafava A, Briganti F, Iorga B, Supuran CT. Protease inhibitors. Part 2. Weakly basic thrombin inhibitors incorporating sulfonyl-aminoguanidine moieties as S1 anchoring groups: synthesis and structure-activity correlations. Journal of Enzyme Inhibition. 15: 235-64. PMID 10811030 DOI: 10.3109/14756360009040686 |
0.356 |
|
2000 |
Iorga B, Eymery F, Savignac P. Controlled Monohalogenation of Phosphonates, Part II: Preparation of Pure Diethyl α-Monohalogenated Alkylphosphonates Synthesis. 2000: 576-580. DOI: 10.1055/S-2000-6375 |
0.76 |
|
2000 |
Eymery F, Iorga B, Savignac P. The Usefulness of Phosphorus Compounds in Alkyne Synthesis Synthesis. 2000: 185-213. DOI: 10.1055/S-2000-6241 |
0.767 |
|
2000 |
Iorga B, Ricard L, Savignac P. Carbanionic displacement reactions at phosphorus. Part III. Cyanomethylphosphonate vs. cyanomethylenediphosphonate. Synthesis and solid-state structures Journal of the Chemical Society-Perkin Transactions 1. 3311-3316. DOI: 10.1039/B003371P |
0.587 |
|
2000 |
Iorga B, Carmichael D, Savignac P. Phosphonate–phosphonochloridate conversion Comptes Rendus De L'AcadéMie Des Sciences - Series Iic - Chemistry. 3: 821-829. DOI: 10.1016/S1387-1609(00)01207-X |
0.543 |
|
2000 |
Iorga B, Eymery F, Carmichael D, Savignac P. Dialkyl 1-Alkynylphosphonates: a Range of Promising Reagents European Journal of Organic Chemistry. 2000: 3103-3115. DOI: 10.1002/1099-0690(200009)2000:18<3103::Aid-Ejoc3103>3.0.Co;2-V |
0.767 |
|
1999 |
Iorga B, Eymery F, Savignac P. The Syntheses and Properties of 1,2-Epoxyalkylphosphonates Synthesis. 1999: 207-224. DOI: 10.1055/S-1999-3378 |
0.752 |
|
1999 |
Eymery F, Iorga B, Savignac P. Synthesis of phosphonates by nucleophilic substitution at phosphorus: The SNP(V) reaction Tetrahedron. 55: 13109-13150. DOI: 10.1016/S0040-4020(99)00822-4 |
0.762 |
|
1999 |
Iorga B, Eymery F, Savignac P. Controlled monohalogenation of phosphonates: A new route to pure α-monohalogenated diethyl benzylphosphonates Tetrahedron. 55: 2671-2686. DOI: 10.1016/S0040-4020(99)00037-X |
0.772 |
|
1998 |
Supuran CT, Scozzafava A, Ilies MA, Iorga B, Cristea T, Briganti F, Chiraleu F, Banciu MD. Carbonic anhydrase inhibitors - Part 53. Synthesis of substituted-pyridinium derivatives of aromatic sulfonamides: The first non-polymeric membrane-impermeable inhibitors with selectivity for isozyme IV European Journal of Medicinal Chemistry. 33: 577-594. DOI: 10.1016/S0223-5234(98)80017-2 |
0.304 |
|
1998 |
Iorga B, Eymery F, Savignac P. An efficient synthesis of tetraethyl fluoromethylenediphosphonate and derivatives from diethyl dibromofluoromethylphosphonate Tetrahedron Letters. 39: 4477-4480. DOI: 10.1016/S0040-4039(98)00821-1 |
0.77 |
|
1998 |
Iorga B, Eymery F, Savignac P. A highly selective synthesis of α-monofluoro- and α-monochloro- benzylphosphonates using electrophilic halogenation of benzylphosphonates carbanions Tetrahedron Letters. 39: 3693-3696. DOI: 10.1016/S0040-4039(98)00648-0 |
0.772 |
|
1998 |
Iorga B, Eymery F, Mouriès V, Savignac P. Phosphorylated aldehydes: Preparations and synthetic uses Tetrahedron. 54: 14637-14677. DOI: 10.1016/S0040-4020(98)00896-5 |
0.758 |
|
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