| Year |
Citation |
Score |
| 2022 |
Colas C, Mouchiroud M, Al Dow M, Kolnohuz A, Gélinas Y, Caron A, Laplante M. DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice. Molecular Metabolism. 67: 101660. PMID 36535626 DOI: 10.1016/j.molmet.2022.101660 |
0.645 |
|
| 2022 |
Vilela VR, Samson N, Nachbar R, Perazza LR, Lachance G, Rokatoarivelo V, Centano-Baez C, Zancan P, Sola-Penna M, Bellmann K, Di Marzo V, Laplante M, Marette A. Adipocyte-specific Nos2 deletion improves insulin resistance and dyslipidemia through brown fat activation in diet-induced obese mice. Molecular Metabolism. 57: 101437. PMID 35033724 DOI: 10.1016/j.molmet.2022.101437 |
0.333 |
|
| 2022 |
Girard R, Tremblay S, Noll C, St-Jean S, Jones C, Gélinas Y, Maloum-Rami F, Perreault N, Laplante M, Carpentier AC, Boudreau F. The transcription factor hepatocyte nuclear factor 4A acts in the intestine to promote white adipose tissue energy storage. Nature Communications. 13: 224. PMID 35017517 DOI: 10.1038/s41467-021-27934-w |
0.338 |
|
| 2021 |
Castro É, Vieira TS, Oliveira TE, Ortiz-Silva M, Andrade ML, Tomazelli CA, Peixoto AS, Sobrinho CR, Moreno MF, Gilio GR, Moreira RJ, Guimarães RC, Perandini LA, Chimin P, Reckziegel P, ... ... Laplante M, et al. Adipocyte-specific mTORC2 deficiency impairs BAT and iWAT thermogenic capacity without affecting glucose uptake and energy expenditure in cold-acclimated mice. American Journal of Physiology. Endocrinology and Metabolism. 321: E592-E605. PMID 34541875 DOI: 10.1152/ajpendo.00587.2020 |
0.359 |
|
| 2021 |
de la Calle Arregui C, Plata-Gómez AB, Deleyto-Seldas N, García F, Ortega-Molina A, Abril-Garrido J, Rodriguez E, Nemazanyy I, Tribouillard L, de Martino A, Caleiras E, Campos-Olivas R, Mulero F, Laplante M, Muñoz J, et al. Limited survival and impaired hepatic fasting metabolism in mice with constitutive Rag GTPase signaling. Nature Communications. 12: 3660. PMID 34135321 DOI: 10.1038/s41467-021-23857-8 |
0.57 |
|
| 2020 |
Al Dow M, Silveira MAD, Poliquin A, Tribouillard L, Fournier É, Trébaol E, Secco B, Villot R, Tremblay F, Bilodeau S, Laplante M. CONTROL OF ADIPOGENIC COMMITMENT BY A STAT3-VSTM2A AXIS. American Journal of Physiology. Endocrinology and Metabolism. PMID 33196296 DOI: 10.1152/ajpendo.00314.2020 |
0.327 |
|
| 2020 |
Marcouiller F, Jochmans-Lemoine A, Ganouna G, Mouchiroud M, Laplante M, Marette A, Joseph V. Metabolic responses to intermittent hypoxia are regulated by sex and gonadal hormones in mice. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05178 |
0.355 |
|
| 2019 |
Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, ... ... Laplante M, et al. The Hepatokine TSK does not affect brown fat thermogenic capacity, body weight gain, and glucose homeostasis. Molecular Metabolism. 30: 184-191. PMID 31767170 DOI: 10.1016/J.Molmet.2019.09.014 |
0.644 |
|
| 2019 |
Mouchiroud M, Camiré É, Aldow M, Caron A, Jubinville É, Turcotte L, Kaci I, Beaulieu MJ, Roy C, Labbé SM, Varin TV, Gélinas Y, Lamothe J, Trottier J, Mitchell PL, ... ... Laplante M, et al. The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis. Jci Insight. 4. PMID 31391339 DOI: 10.1172/Jci.Insight.129492 |
0.583 |
|
| 2019 |
Besse-Patin A, Jeromson S, Levesque-Damphousse P, Secco B, Laplante M, Estall JL. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin. Proceedings of the National Academy of Sciences of the United States of America. PMID 30770439 DOI: 10.1073/pnas.1815150116 |
0.338 |
|
| 2018 |
Wedel J, Bruneau S, Liu K, Kong SW, Sage PT, Sabatini DM, Laplante M, Briscoe DM. Deptor modulates activation responses in CD4 T cells and enhances immunoregulation following transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 29969188 DOI: 10.1111/Ajt.14995 |
0.515 |
|
| 2018 |
Caron A, Briscoe DM, Richard D, Laplante M. DEPTOR at the Nexus of Cancer, Metabolism, and Immunity. Physiological Reviews. 98: 1765-1803. PMID 29897294 DOI: 10.1152/Physrev.00064.2017 |
0.684 |
|
| 2018 |
Wilson AM, Shao Z, Grenier V, Mawambo G, Daudelin JF, Dejda A, Pilon F, Popovic N, Boulet S, Parinot C, Oubaha M, Labrecque N, de Guire V, Laplante M, Lettre G, et al. Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome. Science Immunology. 3. PMID 29549139 DOI: 10.1126/Sciimmunol.Aan4626 |
0.488 |
|
| 2018 |
Carter S, Miard S, Caron A, Sallé-Lefort S, St-Pierre P, Anhê FF, Lavoie-Charland E, Blais-Lecours P, Drolet MC, Lefebvre JS, Lacombe J, Deshaies Y, Couet J, Laplante M, Ferron M, et al. Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B Lymphocyte Transition and Promoting Energy Expenditure. Diabetes. PMID 29496744 DOI: 10.2337/Db17-0558 |
0.762 |
|
| 2017 |
Chechi K, Voisine P, Mathieu P, Laplante M, Bonnet S, Picard F, Joubert P, Richard D. Functional characterization of the Ucp1-associated oxidative phenotype of human epicardial adipose tissue. Scientific Reports. 7: 15566. PMID 29138472 DOI: 10.1038/S41598-017-15501-7 |
0.611 |
|
| 2017 |
Caron A, Mouchiroud M, Gautier N, Labbé SM, Villot R, Turcotte L, Secco B, Lamoureux G, Shum M, Gélinas Y, Marette A, Richard D, Sabatini DM, Laplante M. Loss of hepatic DEPTOR alters the metabolic transition to fasting. Molecular Metabolism. 6: 447-458. PMID 28462079 DOI: 10.1016/J.Molmet.2017.02.005 |
0.749 |
|
| 2017 |
Secco B, Camiré É, Brière MA, Caron A, Billong A, Gélinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad É, ... ... Laplante M, et al. Amplification of Adipogenic Commitment by VSTM2A. Cell Reports. 18: 93-106. PMID 28052263 DOI: 10.1016/J.Celrep.2016.12.015 |
0.752 |
|
| 2016 |
Labbé SM, Mouchiroud M, Caron A, Secco B, Freinkman E, Lamoureux G, Gélinas Y, Lecomte R, Bossé Y, Chimin P, Festuccia WT, Richard D, Laplante M. mTORC1 is Required for Brown Adipose Tissue Recruitment and Metabolic Adaptation to Cold. Scientific Reports. 6: 37223. PMID 27876792 DOI: 10.1038/Srep37223 |
0.737 |
|
| 2016 |
Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nature Communications. 7: 12700. PMID 27624942 DOI: 10.1038/Ncomms12700 |
0.359 |
|
| 2016 |
Labbé SM, Caron A, Chechi K, Laplante M, Lecomte R, Richard D. Metabolic activity of brown, "beige" and white adipose tissues in response to chronic adrenergic stimulation in male mice. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00545.2015. PMID 27143559 DOI: 10.1152/Ajpendo.00545.2015 |
0.734 |
|
| 2016 |
Caron A, Labbé SM, Mouchiroud M, Huard R, Richard D, Laplante M. DEPTOR IN POMC NEURONS AFFECTS LIVER METABOLISM BUT IS DISPENSABLE FOR THE REGULATION OF ENERGY BALANCE. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00549.2015. PMID 27097662 DOI: 10.1152/Ajpregu.00549.2015 |
0.728 |
|
| 2016 |
Caron A, Labbé SM, Lanfray D, Blanchard PG, Villot R, Roy C, Sabatini DM, Richard D, Laplante M. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity. Molecular Metabolism. 5: 102-12. PMID 26909318 DOI: 10.1016/J.Molmet.2015.11.005 |
0.77 |
|
| 2016 |
Lanfray D, Caron A, Roy MC, Laplante M, Morin F, Leprince J, Tonon MC, Richard D. Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice. Elife. 5. PMID 26880548 DOI: 10.7554/Elife.11742 |
0.696 |
|
| 2016 |
Lanfray D, Caron A, Roy M, Laplante M, Morin F, Leprince J, Tonon M, Richard D. Author response: Involvement of the Acyl-CoA binding domain containing 7 in the control of food intake and energy expenditure in mice Elife. DOI: 10.7554/Elife.11742.036 |
0.663 |
|
| 2015 |
Caron A, Richard D, Laplante M. The Roles of mTOR Complexes in Lipid Metabolism. Annual Review of Nutrition. 35: 321-48. PMID 26185979 DOI: 10.1146/Annurev-Nutr-071714-034355 |
0.73 |
|
| 2015 |
Labbé SM, Caron A, Bakan I, Laplante M, Carpentier AC, Lecomte R, Richard D. In vivo measurement of energy substrate contribution to cold-induced brown adipose tissue thermogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2046-58. PMID 25681456 DOI: 10.1096/Fj.14-266247 |
0.71 |
|
| 2015 |
Caron A, Baraboi ED, Laplante M, Richard D. DEP domain-containing mTOR-interacting protein in the rat brain: distribution of expression and potential implication. The Journal of Comparative Neurology. 523: 93-107. PMID 25159114 DOI: 10.1002/Cne.23668 |
0.7 |
|
| 2015 |
Caron A, Labbé SM, Lanfray D, Blanchard PG, Villot R, Roy C, Sabatini DM, Richard D, Laplante M. Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity Molecular Metabolism. DOI: 10.1016/j.molmet.2015.11.005 |
0.721 |
|
| 2014 |
Sood A, Jeyaraju DV, Prudent J, Caron A, Lemieux P, McBride HM, Laplante M, Tóth K, Pellegrini L. A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver. Proceedings of the National Academy of Sciences of the United States of America. 111: 16017-22. PMID 25352671 DOI: 10.1073/Pnas.1408061111 |
0.613 |
|
| 2014 |
Chabot F, Caron A, Laplante M, St-Pierre DH. Interrelationships between ghrelin, insulin and glucose homeostasis: Physiological relevance. World Journal of Diabetes. 5: 328-41. PMID 24936254 DOI: 10.4239/Wjd.V5.I3.328 |
0.612 |
|
| 2014 |
Festuccia WT, Pouliot P, Bakan I, Sabatini DM, Laplante M. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. Plos One. 9: e95432. PMID 24740015 DOI: 10.1371/Journal.Pone.0095432 |
0.577 |
|
| 2013 |
Birsoy K, Festuccia WT, Laplante M. A comparative perspective on lipid storage in animals. Journal of Cell Science. 126: 1541-52. PMID 23658371 DOI: 10.1242/Jcs.104992 |
0.669 |
|
| 2013 |
Laplante M, Sabatini DM. Regulation of mTORC1 and its impact on gene expression at a glance. Journal of Cell Science. 126: 1713-9. PMID 23641065 DOI: 10.1242/Jcs.125773 |
0.6 |
|
| 2012 |
Laplante M, Horvat S, Festuccia WT, Birsoy K, Prevorsek Z, Efeyan A, Sabatini DM. DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity. Cell Metabolism. 16: 202-12. PMID 22883231 DOI: 10.1016/J.Cmet.2012.07.008 |
0.747 |
|
| 2012 |
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 149: 274-93. PMID 22500797 DOI: 10.1016/J.Cell.2012.03.017 |
0.561 |
|
| 2012 |
Bakan I, Laplante M. Connecting mTORC1 signaling to SREBP-1 activation. Current Opinion in Lipidology. 23: 226-34. PMID 22449814 DOI: 10.1097/Mol.0B013E328352Dd03 |
0.447 |
|
| 2012 |
Li Z, Miard S, Laplante M, Sonenberg N, Picard F. Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway. Molecular and Cellular Endocrinology. 358: 63-8. PMID 22410287 DOI: 10.1016/J.Mce.2012.02.022 |
0.431 |
|
| 2012 |
Laplante M, Sabatini DM. mTOR Signaling. Cold Spring Harbor Perspectives in Biology. 4. PMID 22129599 DOI: 10.1101/cshperspect.a011593 |
0.431 |
|
| 2010 |
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 468: 1100-4. PMID 21179166 DOI: 10.1038/Nature09584 |
0.6 |
|
| 2010 |
Laplante M, Sabatini DM. mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 3281-2. PMID 20167806 DOI: 10.1073/Pnas.1000323107 |
0.583 |
|
| 2010 |
Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y. Preliminary report: pharmacologic 11beta-hydroxysteroid dehydrogenase type 1 inhibition increases hepatic fat oxidation in vivo and expression of related genes in rats fed an obesogenic diet. Metabolism: Clinical and Experimental. 59: 114-7. PMID 19766266 DOI: 10.1016/J.Metabol.2009.07.015 |
0.592 |
|
| 2009 |
Laplante M, Sabatini DM. An emerging role of mTOR in lipid biosynthesis. Current Biology : Cb. 19: R1046-52. PMID 19948145 DOI: 10.1016/J.Cub.2009.09.058 |
0.59 |
|
| 2009 |
Laplante M, Sabatini DM. mTOR signaling at a glance. Journal of Cell Science. 122: 3589-94. PMID 19812304 DOI: 10.1242/Jcs.051011 |
0.554 |
|
| 2009 |
Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 137: 873-86. PMID 19446321 DOI: 10.1016/J.Cell.2009.03.046 |
0.556 |
|
| 2009 |
Festuccia WT, Laplante M, Brûlé S, Houde VP, Achouba A, Lachance D, Pedrosa ML, Silva ME, Guerra-Sá R, Couet J, Arsenault M, Marette A, Deshaies Y. Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation. Journal of Molecular and Cellular Cardiology. 47: 85-95. PMID 19397913 DOI: 10.1016/J.Yjmcc.2009.04.011 |
0.612 |
|
| 2009 |
Berthiaume M, Laplante M, Festuccia WT, Berger JP, Thieringer R, Deshaies Y. Additive action of 11β-HSD1 inhibition and PPAR-γ agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats. International Journal of Obesity. 33: 601-604. PMID 19223847 DOI: 10.1038/Ijo.2009.33 |
0.592 |
|
| 2009 |
Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Richard D, Deshaies Y. The PPARgamma agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1327-35. PMID 19211718 DOI: 10.1152/Ajpregu.91012.2008 |
0.704 |
|
| 2009 |
Festuccia WT, Blanchard PG, Turcotte V, Laplante M, Sariahmetoglu M, Brindley DN, Deshaies Y. Depot-specific effects of the PPARgamma agonist rosiglitazone on adipose tissue glucose uptake and metabolism. Journal of Lipid Research. 50: 1185-94. PMID 19201733 DOI: 10.1194/Jlr.M800620-Jlr200 |
0.644 |
|
| 2009 |
Laplante M, Festuccia WT, Soucy G, Blanchard PG, Renaud A, Berger JP, Olivecrona G, Deshaies Y. Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R57-66. PMID 18971352 DOI: 10.1152/Ajpregu.90552.2008 |
0.67 |
|
| 2008 |
Dallaire P, Bellmann K, Laplante M, Gélinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57: 1999-2011. PMID 18458147 DOI: 10.2337/Db08-0540 |
0.645 |
|
| 2008 |
Festuccia WT, Oztezcan S, Laplante M, Berthiaume M, Michel C, Dohgu S, Denis RG, Brito MN, Brito NA, Miller DS, Banks WA, Bartness TJ, Richard D, Deshaies Y. Peroxisome proliferator-activated receptor-gamma-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status. Endocrinology. 149: 2121-30. PMID 18218698 DOI: 10.1210/En.2007-1553 |
0.7 |
|
| 2007 |
Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, Hofmann SM, Schraw T, Durand JL, Li H, Li G, Jelicks LA, Mehler MF, Hui DY, Deshaies Y, Shulman GI, et al. Obesity-associated improvements in metabolic profile through expansion of adipose tissue. The Journal of Clinical Investigation. 117: 2621-37. PMID 17717599 DOI: 10.1172/Jci31021 |
0.669 |
|
| 2007 |
Cui W, Paglialunga S, Kalant D, Lu H, Roy C, Laplante M, Deshaies Y, Cianflone K. Acylation-stimulating protein/C5L2-neutralizing antibodies alter triglyceride metabolism in vitro and in vivo. American Journal of Physiology. Endocrinology and Metabolism. 293: E1482-91. PMID 17711993 DOI: 10.1152/Ajpendo.00565.2006 |
0.588 |
|
| 2007 |
Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y. 11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues. American Journal of Physiology. Endocrinology and Metabolism. 293: E1045-52. PMID 17666487 DOI: 10.1152/Ajpendo.00276.2007 |
0.648 |
|
| 2007 |
Berthiaume M, Laplante M, Tchernof A, Deshaies Y. Metabolic action of peroxisome proliferator-activated receptor gamma agonism in rats with exogenous hypercorticosteronemia. International Journal of Obesity (2005). 31: 1660-70. PMID 17579631 DOI: 10.1038/Sj.Ijo.0803668 |
0.591 |
|
| 2007 |
Berthiaume M, Laplante M, Festuccia W, Gélinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y. Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1. Endocrinology. 148: 2391-7. PMID 17272400 DOI: 10.1210/En.2006-1199 |
0.657 |
|
| 2007 |
Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Deshaies Y. Involvement of adipose tissues in the early hypolipidemic action of PPARγ agonism in the rat American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 292: R1408-R1417. PMID 17170230 DOI: 10.1152/Ajpregu.00761.2006 |
0.649 |
|
| 2006 |
Laplante M, Festuccia WT, Soucy G, Gélinas Y, Lalonde J, Berger JP, Deshaies Y. Mechanisms of the depot specificity of peroxisome proliferator-activated receptor γ action on adipose tissue metabolism Diabetes. 55: 2771-2778. PMID 17003342 DOI: 10.2337/Db06-0551 |
0.647 |
|
| 2006 |
Festuccia WT, Laplante M, Berthiaume M, Gélinas Y, Deshaies Y. PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control Diabetologia. 49: 2427-2436. PMID 16906479 DOI: 10.1007/S00125-006-0336-Y |
0.643 |
|
| 2004 |
Combs TP, Pajvani UB, Berg AH, Lin Y, Jelicks LA, Laplante M, Nawrocki AR, Rajala MW, Parlow AF, Cheeseboro L, Ding YY, Russell RG, Lindemann D, Hartley A, Baker GR, et al. A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity. Endocrinology. 145: 367-83. PMID 14576179 DOI: 10.1210/En.2003-1068 |
0.663 |
|
| 2003 |
Laplante M, Sell H, MacNaul KL, Richard D, Berger JP, Deshaies Y. PPAR-gamma activation mediates adipose depot-specific effects on gene expression and lipoprotein lipase activity: mechanisms for modulation of postprandial lipemia and differential adipose accretion. Diabetes. 52: 291-9. PMID 12540599 DOI: 10.2337/Diabetes.52.2.291 |
0.735 |
|
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