John R. Naber - Publications

Affiliations: 
Merck, Boston, MA 

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Corcoran EB, McMullen JP, Lévesque F, Wismer MK, Naber JR. Use of Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: the translation of a photocatalytic C-N cross-coupling from lab scale to multikilogram scale. Angewandte Chemie (International Ed. in English). PMID 32243016 DOI: 10.1002/Anie.201915412  0.453
2019 Christensen M, Adedeji F, Grosser S, Zawatzky K, Ji Y, Liu J, Jurica JA, Naber JR, Hein JE. Development of an automated kinetic profiling system with online HPLC for reaction optimization Reaction Chemistry & Engineering. 4: 1555-1558. DOI: 10.1039/C9Re00086K  0.437
2019 SalehiMarzijarani N, Snead DR, McMullen JP, Lévesque F, Weisel M, Varsolona RJ, Lam Y, Liu Z, Naber JR. One-Step Synthesis of 2‑Fluoroadenine UsingHydrogen Fluoride Pyridine in a Continuous Flow Operation Organic Process Research & Development. 23: 1522-1528. DOI: 10.1021/Acs.Oprd.9B00178  0.43
2019 Snead DR, Lévesque F, Morris WJ, Naber JR. An improved Balz-Schiemann reaction enabled by ionic liquids and continuous processing Tetrahedron. 75: 4261-4265. DOI: 10.1016/J.Tet.2019.05.020  0.376
2018 Thaisrivongs DA, Morris WJ, Tan L, Song ZJ, Lyons TW, Waldman JH, Naber JR, Chen W, Chen L, Zhang B, Yang J. A Next Generation Synthesis of BACE1 Inhibitor Verubecestat (MK-8931). Organic Letters. PMID 29481097 DOI: 10.1021/Acs.Orglett.8B00259  0.407
2018 Lévesque F, Rogus NJ, Spencer G, Grigorov P, McMullen JP, Thaisrivongs DA, Davies IW, Naber JR. Advancing Flow Chemistry Portability: A Simplified Approach to Scaling Up Flow Chemistry Organic Process Research & Development. 22: 1015-1021. DOI: 10.1021/Acs.Oprd.8B00063  0.37
2018 Thaisrivongs DA, Naber JR, Rogus NJ, Spencer G. Development of an Organometallic Flow Chemistry Reaction at Pilot-Plant Scale for the Manufacture of Verubecestat Organic Process Research & Development. 22: 403-408. DOI: 10.1021/Acs.Oprd.7B00385  0.372
2016 Thaisrivongs DA, Naber JR, McMullen JP. Using Flow To Outpace Fast Proton Transfer in an Organometallic Reaction for the Manufacture of Verubecestat (MK-8931) Organic Process Research & Development. 20: 1997-2004. DOI: 10.1021/Acs.Oprd.6B00247  0.409
2011 Noël T, Naber JR, Hartman RL, Mcmullen JP, Jensen KF, Buchwald SL. Palladium-catalyzed amination reactions in flow: Overcoming the challenges of clogging via acoustic irradiation Chemical Science. 2: 287-290. DOI: 10.1039/C0Sc00524J  0.617
2010 Naber JR, Fors BP, Wu X, Gunn J, Buchwald SL. STILLE CROSS-COUPLING REACTIONS OF ARYL MESYLATES AND TOSYLATES USING A BIARYLPHOSPHINE BASED CATALYST SYSTEM. Heterocycles. 80: 1215-1226. PMID 23596345 DOI: 10.3987/Com-09-S(S)105  0.608
2010 Naber JR, Buchwald SL. Packed-bed reactors for continuous-flow C-N cross-coupling. Angewandte Chemie (International Ed. in English). 49: 9469-74. PMID 21038337 DOI: 10.1002/Anie.201004425  0.486
2010 Hartman RL, Naber JR, Buchwald SL, Jensen KF. Multistep microchemical synthesis enabled by microfluidic distillation. Angewandte Chemie (International Ed. in English). 49: 899-903. PMID 20025004 DOI: 10.1002/Anie.200904634  0.456
2010 Hartman RL, Naber JR, Zaborenko N, Buchwald SL, Jensen KF. Overcoming the challenges of solid bridging and constriction during Pd-catalyzed C-N bond formation in microreactors Organic Process Research and Development. 14: 1347-1357. DOI: 10.1021/Op100154D  0.541
2008 Naber JR, Buchwald SL. Palladium-catalyzed Stille cross-coupling reaction of aryl chlorides using a pre-milled palladium acetate and XPhos catalyst system Advanced Synthesis and Catalysis. 350: 957-961. DOI: 10.1002/Adsc.200800032  0.605
2007 Hughes G, Devine PN, Naber JR, O'shea PD, Foster BS, McKay DJ, Volante RP. Diastereoselective reductive amination of aryl trifluoromethyl ketones and alpha-amino esters. Angewandte Chemie (International Ed. in English). 46: 1839-42. PMID 17450610 DOI: 10.1002/Anie.200603745  0.305
Show low-probability matches.