Year |
Citation |
Score |
2022 |
Kumar D, Kashyap MK, Yu Z, Spaanderman I, Villa R, Kipps TJ, La Clair JJ, Burkart MD, Castro JE. Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B. Aging. 14: 2081-2100. PMID 35230971 DOI: 10.18632/aging.203924 |
0.681 |
|
2016 |
Crews LA, Balaian L, Delos Santos NP, Leu HS, Court AC, Lazzari E, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Kulidjian A, Storb R, Morris SR, Ball ED, Burkart MD, et al. RNA Splicing Modulation Selectively Impairs Leukemia Stem Cell Maintenance in Secondary Human AML. Cell Stem Cell. PMID 27570067 DOI: 10.1016/J.Stem.2016.08.003 |
0.553 |
|
2016 |
Kumar D, Kashyap MK, La Clair JJ, Villa R, Spaanderman I, Chien S, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Selectivity in Small Molecule Splicing Modulation. Acs Chemical Biology. PMID 27499047 DOI: 10.1021/Acschembio.6B00399 |
0.681 |
|
2016 |
Crews LA, Balaian L, Leu HS, Santos NPD, Court AC, Sadarangani A, Zipeto MA, Clair JJL, Villa R, Morris SR, Storb R, Kulidjian A, Ball ED, Burkart MD, Jamieson CHM. Abstract 915: RNA processing signatures of normal versus malignant progenitor cell aging predict leukemia stem cell sensitivity to RNA splicing modulation Cancer Research. 76: 915-915. DOI: 10.1158/1538-7445.Am2016-915 |
0.548 |
|
2015 |
Kashyap MK, Kumar D, Villa R, La Clair JJ, Benner C, Sasik R, Jones H, Ghia EM, Rassenti LZ, Kipps TJ, Burkart MD, Castro JE. Targeting the spliceosome in chronic lymphocytic leukemia with the macrolides FD-895 and pladienolide-B. Haematologica. 100: 945-54. PMID 25862704 DOI: 10.3324/Haematol.2014.122069 |
0.682 |
|
2015 |
Crews LA, Balaian L, Leu H, Delos Santos N, Court AC, Sadarangani A, Zipeto MA, La Clair JJ, Villa R, Morris S, Storb RF, Kulidjian A, Ball ED, Burkart MD, Jamieson C. RNA Splicing Modulation Impairs Acute Myeloid Leukemia Stem Cell Maintenance Blood. 126: 567-567. DOI: 10.1182/Blood.V126.23.567.567 |
0.557 |
|
2013 |
Villa R, Kashyap MK, Kumar D, Kipps TJ, Castro JE, La Clair JJ, Burkart MD. Stabilized cyclopropane analogs of the splicing inhibitor FD-895. Journal of Medicinal Chemistry. 56: 6576-82. PMID 23919277 DOI: 10.1021/Jm400861T |
0.688 |
|
2013 |
Rothmann M, Kang M, Villa R, Ntai I, La Clair JJ, Kelleher NL, Chapman E, Burkart MD. Metabolic perturbation of an essential pathway: evaluation of a glycine precursor of coenzyme A. Journal of the American Chemical Society. 135: 5962-5. PMID 23550886 DOI: 10.1021/Ja400795M |
0.576 |
|
2013 |
Kumar D, Kashyap MK, Spaanderman I, Villa R, Rassenti L, La Clair J, Burkat MD, Kipps TJ, Castro JE. A Cyclopropane-Derived Stable Analog Of Fd-895 Induces Apoptosis and Inhibition Of mRNA Splicing In Lymphoma and Chronic Lymphocytic Leukemia: A Novel Therapeutic Approach Blood. 122: 2884-2884. DOI: 10.1182/Blood.V122.21.2884.2884 |
0.669 |
|
2012 |
Villa R, Mandel AL, Jones BD, La Clair JJ, Burkart MD. Structure of FD-895 revealed through total synthesis. Organic Letters. 14: 5396-9. PMID 23072504 DOI: 10.1021/Ol3023006 |
0.624 |
|
2012 |
Villa RA, Xu Q, Kwon O. Total synthesis of (±)-hirsutine: application of phosphine-catalyzed imine-allene [4 + 2] annulation. Organic Letters. 14: 4634-7. PMID 22920858 DOI: 10.1021/Ol302077N |
0.624 |
|
Show low-probability matches. |