Jeffrey J. Bednarski, Ph.D.

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
anti-DNA autoantibody structure and function, and the identification of novel molecular targets and small molecules for the treatment of autoimmune diseases and cancer
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Gary D. Glick grad student 2003 University of Michigan
 (Modulation of activation -induced cell death in lymphocytes by a pro-apoptotic benzodiazepine.)
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Publications

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Johnston R, Mathias B, Crowley SJ, et al. (2022) Nuclease-independent functions of RAG1 direct distinct DNA damage responses in B cells. Embo Reports. e55429
Johnston R, White LS, Bednarski JJ. (2022) Assessing DNA Damage Responses Using B Lymphocyte Cultures. Methods in Molecular Biology (Clifton, N.J.). 2444: 69-80
Bhatt ST, Bednarski JJ. (2020) Immune Reconstitution in Pediatric Patients Following Hematopoietic Cell Transplant for Non-malignant Disorders. Frontiers in Immunology. 11: 1988
Blincoe A, Heeg M, Campbell PK, et al. (2020) Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis. Journal of Clinical Immunology
Chan AY, Leiding JW, Liu X, et al. (2020) Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. Frontiers in Immunology. 11: 239
Keller MD, Hanley PJ, Zhang N, et al. (2020) Third-Party Virus-Specific T-Cell Infusion for Treatment of Refractory Viral Infections: Interim Results from PBMTC SUP1701 Biology of Blood and Marrow Transplantation. 26: S89-S90
Thakar MS, Logan B, Buckley RH, et al. (2020) Transplantation Outcomes for Children with Severe Combined Immune Deficiency (SCID) Have Improved over Time: A 36-Year Summary Report By the Primary Immune Deficiency Treatment Consortium (PIDTC) Biology of Blood and Marrow Transplantation. 26: S18-S19
Greenberg ZJ, Monlish DA, Bartnett RL, et al. (2019) The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. Journal of Immunology (Baltimore, Md. : 1950)
Soodgupta D, White LS, Yang W, et al. (2019) RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex. Cell Reports. 29: 829-843.e5
Bhatt ST, Schulz G, Hente M, et al. (2019) A single-center experience using alemtuzumab, fludarabine, melphalan, and thiotepa as conditioning for transplantation in pediatric patients with chronic granulomatous disease. Pediatric Blood & Cancer. e28030
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