Susan C. MacLauchlan, Ph.D.

Affiliations: 
2012 Yale University, New Haven, CT 
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"Susan MacLauchlan"

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Themis R. Kyriakides grad student 2012 Yale
 (Negative regulation of the angiogenesis inhibitor thrombospondin 2 (TSP2) by nitric oxide and hypoxia.)
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Publications

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Zuriaga MA, Fuster JJ, Farb MG, et al. (2017) Activation of non-canonical WNT signaling in human visceral adipose tissue contributes to local and systemic inflammation. Scientific Reports. 7: 17326
MacLauchlan SC, Calabro NE, Huang Y, et al. (2017) HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2. Matrix Biology : Journal of the International Society For Matrix Biology
Fuster JJ, MacLauchlan S, Zuriaga MA, et al. (2017) Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (New York, N.Y.)
Fuster JJ, Maclauchlan S, Zuriaga MA, et al. (2017) Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis in hyperlipidemic mice Atherosclerosis. 263: e14
Kristofik N, Calabro NE, Tian W, et al. (2016) Impaired von Willebrand factor adhesion and platelet response in thrombospondin-2 knockout mice. Blood
Kikuchi R, Nakamura K, MacLauchlan S, et al. (2014) An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nature Medicine. 20: 1464-71
Parker-Duffen JL, Nakamura K, Silver M, et al. (2014) Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. The Journal of Biological Chemistry. 289: 16200-13
Shimizu I, Aprahamian T, Kikuchi R, et al. (2014) Vascular rarefaction mediates whitening of brown fat in obesity. The Journal of Clinical Investigation. 124: 2099-112
MacLauchlan S, Yu J, Parrish M, et al. (2011) Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proceedings of the National Academy of Sciences of the United States of America. 108: E1137-45
Kyriakides TR, Maclauchlan S. (2009) The role of thrombospondins in wound healing, ischemia, and the foreign body reaction. Journal of Cell Communication and Signaling. 3: 215-25
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