Rhine R. Shen, Ph.D.

Affiliations: 
2006 University of California, Los Angeles, Los Angeles, CA 
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"Rhine Shen"

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Michael Teitell grad student 2006 UCLA
 (TCL1-mediated mature B cell lymphomagenesis.)
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Publications

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Shen RR, Zhou AY, Kim E, et al. (2015) TRAF2 is an NF-κB-activating oncogene in epithelial cancers. Oncogene. 34: 209-16
Zhu Z, Aref AR, Cohoon TJ, et al. (2014) Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discovery. 4: 452-65
Hagerstrand D, Tong A, Schumacher SE, et al. (2013) Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discovery. 3: 1044-57
Zhou AY, Shen RR, Kim E, et al. (2013) IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. Cell Reports. 3: 724-33
Shen RR, Zhou AY, Kim E, et al. (2012) IκB kinase ε phosphorylates TRAF2 to promote mammary epithelial cell transformation. Molecular and Cellular Biology. 32: 4756-68
Creton S, Aardema MJ, Carmichael PL, et al. (2012) Cell transformation assays for prediction of carcinogenic potential: state of the science and future research needs. Mutagenesis. 27: 93-101
Shen RR, Hahn WC. (2011) Emerging roles for the non-canonical IKKs in cancer. Oncogene. 30: 631-41
Hutti JE, Shen RR, Abbott DW, et al. (2009) Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation. Molecular Cell. 34: 461-72
Frank MJ, Dawson DW, Bensinger SJ, et al. (2009) Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. Blood. 113: 2478-87
Boehm JS, Zhao JJ, Yao J, et al. (2007) Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell. 129: 1065-79
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