Hsiao-Wen Chen, Ph.D.

2007

Michael Teitell	grad student	2007	UCLA
(The TCL1 oncoprotein interacting partner polynucleotide phosphorylase is an intermembrane space ribonuclease that maintains mitochondrial homeostasis.)

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Wang C, Chen H, Zhang M, et al. (2016) Malate-aspartate shuttle inhibitor aminooxyacetic acid leads to decreased intracellular ATP levels and altered cell cycle of C6 glioma cells by inhibiting glycolysis. Cancer Letters
Ma W, Zhang X, Li M, et al. (2016) Proapoptotic RYBP interacts with FANK1 and induces tumor cell apoptosis through the AP-1 signaling pathway. Cellular Signalling
Wang G, Chen HW, Oktay Y, et al. (2010) PNPASE regulates RNA import into mitochondria. Cell. 142: 456-67
Chen HW, Koehler CM, Teitell MA. (2007) Human polynucleotide phosphorylase: location matters Trends in Cell Biology. 17: 600-608
French SW, Dawson DW, Chen HW, et al. (2007) The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity. Cancer Letters. 248: 198-210
Chen HW, Rainey RN, Balatoni CE, et al. (2006) Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis Molecular and Cellular Biology. 26: 8475-8487
Rainey RN, Glavin JD, Chen HW, et al. (2006) A new function in translocation for the mitochondrial i-AAA protease Yme1: Import of polynucleotide phosphorylase into the intermembrane space Molecular and Cellular Biology. 26: 8488-8497