John J. Lemasters

Affiliations: 
Biomedical Engineering Joint Program University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Biomedical
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"John Lemasters"
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Publications

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Hu J, Nieminen AL, Weemhoff JL, et al. (2023) The mitochondrial calcium uniporter mediates mitochondrial Fe uptake and hepatotoxicity after acetaminophen. Toxicology and Applied Pharmacology. 479: 116722
Kholmukhamedov A, Li L, Lindsey CC, et al. (2022) A new fluorescent sensor mitoferrofluor indicates the presence of chelatable iron in polarized and depolarized mitochondria. The Journal of Biological Chemistry. 102336
Adelusi OB, Ramachandran A, Lemasters JJ, et al. (2022) The role of Iron in lipid peroxidation and protein nitration during acetaminophen-induced liver injury in mice. Toxicology and Applied Pharmacology. 445: 116043
Samuvel DJ, Li L, Krishnasamy Y, et al. (2022) Mitochondrial depolarization after acute ethanol treatment drives mitophagy in living mice. Autophagy. 1-15
Lemasters JJ. (2021) Metabolic implications of non-Electrogenic ATP/ADP exchange in Cancer cells: A mechanistic basis for the Warburg effect. Biochimica Et Biophysica Acta. Bioenergetics. 148410
Wimborne HJ, Hu J, Takemoto K, et al. (2020) Aldehyde dehydrogenase-2 activation decreases acetaminophen hepatotoxicity by prevention of mitochondrial depolarization. Toxicology and Applied Pharmacology. 114982
Hu J, Lemasters JJ. (2020) Suppression of iron mobilization from lysosomes to mitochondria attenuates liver injury after acetaminophen overdose in vivo in mice: Protection by minocycline. Toxicology and Applied Pharmacology. 114930
Lemasters JJ, Jaeschke H. (2020) Oxidative Stress and Inflammation in the Liver Liver. 714-727
Krishnasamy Y, Gooz M, Li L, et al. (2019) Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. International Journal of Physiology, Pathophysiology and Pharmacology. 11: 190-204
Heslop KA, Rovini A, Hunt EG, et al. (2019) JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells. Biochemical Pharmacology. 113728
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