Sarah Harcum

Affiliations: 
Bioengineering Clemson University, Clemson, SC, United States 
Area:
Biomedical Engineering, Molecular Biology
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"Sarah Harcum"
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Publications

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Chitwood DG, Uy L, Fu W, et al. (2023) Dynamics of Amino Acid Metabolism, Gene Expression, and Circulomics in a Recombinant Chinese Hamster Ovary Cell Line Adapted to Moderate and High Levels of Extracellular Lactate. Genes. 14
Chitwood DG, Wang Q, Klaubert SR, et al. (2023) Microevolutionary dynamics of eccDNA in Chinese hamster ovary cells grown in fed-batch cultures under control and lactate-stressed conditions. Scientific Reports. 13: 1200
Synoground BF, McGraw CE, Elliott KS, et al. (2021) Transient ammonia stress on Chinese hamster ovary (CHO) cells yield alterations to alanine metabolism and IgG glycosylation profiles. Biotechnology Journal. e2100098
Wang J, Zhou J, Gowtham YK, et al. (2017) Antibody Purification from CHO Cell Supernatant Using New Multimodal Membranes. Biotechnology Progress
Brodsky AN, Caldwell M, Bae S, et al. (2014) Glycosylation-related genes in NS0 cells are insensitive to moderately elevated ammonium concentrations. Journal of Biotechnology. 187: 78-86
Baig F, Fernando LP, Salazar MA, et al. (2014) Dynamic transcriptional response of Escherichia coli to inclusion body formation. Biotechnology and Bioengineering. 111: 980-99
Salazar MA, Fernando LP, Baig F, et al. (2013) The effects of protein solubility on the RNA Integrity Number (RIN) for recombinant Escherichia coli. Biochemical Engineering Journal. 79: 129-135
Brodsky AN, Caldwell M, Harcum SW. (2012) Glycosylation and post-translational modification gene expression analysis by DNA microarrays for cultured mammalian cells. Methods (San Diego, Calif.). 56: 408-17
Haddadin FT, Kurtz H, Harcum SW. (2009) Serine hydroxamate and the transcriptome of high cell density recombinant Escherichia coli MG1655. Applied Biochemistry and Biotechnology. 157: 124-39
Chen P, Harcum SW. (2007) Differential display identifies genes in Chinese hamster ovary cells sensitive to elevated ammonium. Applied Biochemistry and Biotechnology. 141: 349-59
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