Maureen L. Upton, Ph.D.

Affiliations: 
2007 Duke University, Durham, NC 
Area:
Biomedical Engineering
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"Maureen Upton"

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Lori A. Setton grad student 2007 Duke (E-Tree)
 (Theoretical predictions and experimental measurements of the micromechanical environment of meniscus cells.)
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Publications

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Upton ML, Gilchrist CL, Guilak F, et al. (2008) Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. Biophysical Journal. 95: 2116-24
Upton ML, Hennerbichler A, Fermor B, et al. (2006) Biaxial strain effects on cells from the inner and outer regions of the meniscus. Connective Tissue Research. 47: 207-14
Guilak F, Alexopoulos LG, Upton ML, et al. (2006) The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage. Annals of the New York Academy of Sciences. 1068: 498-512
Upton ML, Chen J, Setton LA. (2006) Region-specific constitutive gene expression in the adult porcine meniscus. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1562-70
Upton ML, Guilak F, Laursen TA, et al. (2006) Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus. Biomechanics and Modeling in Mechanobiology. 5: 140-9
Upton M, Guilak F, Laursen T, et al. (2006) Biphasic finite element predictions for region-specific meniscus cell-matrix mechanics Journal of Biomechanics. 39: S407
Alexopoulos LG, Williams GM, Upton ML, et al. (2005) Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage. Journal of Biomechanics. 38: 509-17
Upton ML, Laursen TA, Guilak F, et al. (2005) Finite element modeling of region-specific cell-matrix interactions in the meniscus Proceedings of the 2005 Summer Bioengineering Conference. 2005: 229-230
Upton ML, Chen J, Guilak F, et al. (2003) Differential effects of static and dynamic compression on meniscal cell gene expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 963-9
Upton ML, Chen J, Guilak F, et al. (2002) Static compression inhibits matrix protein gene expression and increases collagenase gene expression in the meniscus Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 438-439
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