Andrew J. Simnick, Ph.D.

Affiliations: 
2010 Biomedical Engineering Duke University, Durham, NC 
Area:
Biomedical Engineering, Materials Science Engineering, Molecular Biology
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"Andrew Simnick"

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Ashutosh Chilkoti grad student 2010 Duke
 (Affinity-modulation drug delivery using thermosensitive elastin-like polypeptide block copolymers.)
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Publications

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Manzoor AA, Lindner LH, Landon CD, et al. (2012) Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Research. 72: 5566-75
Simnick AJ, Amiram M, Liu W, et al. (2011) In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide. Journal of Controlled Release : Official Journal of the Controlled Release Society. 155: 144-51
Simnick AJ, Valencia CA, Liu R, et al. (2010) Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer. Acs Nano. 4: 2217-27
Liu W, MacKay JA, Dreher MR, et al. (2010) Injectable intratumoral depot of thermally responsive polypeptide-radionuclide conjugates delays tumor progression in a mouse model. Journal of Controlled Release : Official Journal of the Controlled Release Society. 144: 2-9
Hucknall A, Simnick AJ, Hill RT, et al. (2009) Versatile synthesis and micropatterning of nonfouling polymer brushes on the wafer scale. Biointerphases. 4: FA50-7
MacKay JA, Chen M, McDaniel JR, et al. (2009) Self-assembling chimeric polypeptide-doxorubicin conjugate nanoparticles that abolish tumours after a single injection. Nature Materials. 8: 993-9
Chow D, Nunalee ML, Lim DW, et al. (2008) Peptide-based Biopolymers in Biomedicine and Biotechnology. Materials Science & Engineering. R, Reports : a Review Journal. 62: 125-155
Dreher MR, Simnick AJ, Fischer K, et al. (2008) Temperature triggered self-assembly of polypeptides into multivalent spherical micelles. Journal of the American Chemical Society. 130: 687-94
Simnick AJ, Lim DW, Chow D, et al. (2007) Biomedical and biotechnological applications of Elastin-like polypeptides Polymer Reviews. 47: 121-154
Pyhtila JW, Ma H, Simnick AJ, et al. (2006) Analysis of long range correlations due to coherent light scattering from in-vitro cell arrays using angle-resolved low coherence interferometry. Journal of Biomedical Optics. 11: 34022
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