Kevin J. Hamblett, Ph.D.

Affiliations: 
2002 University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering, Pharmacy, Radiology, Oncology
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"Kevin Hamblett"

Parents

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Patrick S. Stayton grad student 2002 University of Washington
 (Optimization of pretargeted radioimmunotherapy.)
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Publications

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Hamblett KJ, Le T, Rock BM, et al. (2016) Altering antibody drug conjugate binding to the Neonatal Fc Receptor impacts efficacy and tolerability. Molecular Pharmaceutics
Hamblett KJ, Kozlosky CJ, Siu S, et al. (2015) AMG 595, an Anti-EGFRvIII Antibody-Drug Conjugate, Induces Potent Antitumor Activity against EGFRvIII-Expressing Glioblastoma. Molecular Cancer Therapeutics. 14: 1614-24
McDonagh CF, Turcott E, Westendorf L, et al. (2006) Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment. Protein Engineering, Design & Selection : Peds. 19: 299-307
Sun MM, Beam KS, Cerveny CG, et al. (2005) Reduction-alkylation strategies for the modification of specific monoclonal antibody disulfides. Bioconjugate Chemistry. 16: 1282-90
Hamblett KJ, Press OW, Meyer DL, et al. (2005) Role of biotin-binding affinity in streptavidin-based pretargeted radioimmunotherapy of lymphoma. Bioconjugate Chemistry. 16: 131-8
Hamblett KJ, Barton J, Cerveny CG, et al. (2005) SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies. Blood. 106: 610-610
Hamblett KJ, Kegley BB, Hamlin DK, et al. (2002) A streptavidin-biotin binding system that minimizes blocking by endogenous biotin. Bioconjugate Chemistry. 13: 588-98
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