Bertrand C. Tanner, Ph.D.

Affiliations: 
2007 University of Washington, Seattle, Seattle, WA 
Area:
Physiology Biology, Molecular Biology
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"Bertrand Tanner"

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Michael Regnier grad student 2007 University of Washington
 (Spatial coupling between sarcomeric proteins controls calcium ion-sensitive contraction in muscle: A complementary research approach integrating theory with experiments.)
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Publications

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Awinda PO, Watanabe M, Bishaw Y, et al. (2020) Mavacamten Decreases Maximal Force and Ca2+-Sensitivity of Contraction in Myocardial Strips From a Mouse Model for Hypertrophic Cardiomyopathy Biophysical Journal. 118
Awinda PO, Brutman KM, Bishaw Y, et al. (2020) Targeting the Myosin OFF-ON Equilibrium to Modulate Length-Dependent Contraction in Human Myocardial Strips Biophysical Journal. 118
Fenwick AJ, Lin DC, Tanner BC. (2020) Cross-Bridge Cycling Kinetics Slow at Longer Muscle Length in Tetanic Contracting Mouse Soleus Muscle Biophysical Journal. 118: 278a
Fenwick AJ, Awinda PO, Yarbrough-Jones JA, et al. (2019) Demembranated Skeletal and Cardiac Fibers Produce Less Force with Altered Cross-Bridge Kinetics in a Mouse Model for Limb-Girdle Muscular Dystrophy 2i. American Journal of Physiology. Cell Physiology
Tanner BC, Campbell KS, Qadan M, et al. (2019) Anti-S2 Peptides Modulate Myosin Coiled Coil Structure and Shift Force-PCa Curves in Human Cardiac Muscle Biophysical Journal. 116: 263a
Fenwick AJ, Tanner BC. (2017) Computational Simulations of Load-Dependent Myosin Kinetics during Muscle Shortening and Lengthening Biophysical Journal. 112: 116a
Li K, Methawasin M, Granzier H, et al. (2017) Sarcomere Lengthdependent Effects on the Ca 2+ -Troponin Regulation in Skinned Myocardial Fiber from Titin RBM20 Deletion Mice Biophysical Journal. 112: 257a
Fenwick AJ, Leighton SR, Tanner BC. (2016) Myosin MgADP Release Rate Decreases as Sarcomere Length Increases in Skinned Rat Soleus Muscle Fibers. Biophysical Journal. 111: 2011-2023
Pulcastro HC, Awinda PO, Methawasin M, et al. (2016) Increased Titin Compliance Reduced Length-Dependent Contraction and Slowed Cross-Bridge Kinetics in Skinned Myocardial Strips from Rbm (20ΔRRM) Mice. Frontiers in Physiology. 7: 322
Pulcastro HC, Awinda PO, Breithaupt JJ, et al. (2016) Effects of myosin light chain phosphorylation on length-dependent myosin kinetics in skinned rat myocardium. Archives of Biochemistry and Biophysics
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