Jonathan N. Sachs
Affiliations: | Biomedical Engineering | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Biomedical Engineering, General BiophysicsGoogle:
"Jonathan Sachs"Children
Sign in to add traineeJason D. Perlmutter | grad student | 2011 | UMN |
Christopher C. Valley | grad student | 2012 | UMN |
Anthony R. Braun | grad student | 2014 | UMN |
Andrew Kyle Lewis | grad student | 2015 | UMN (Chemistry Tree) |
Mu Yang | post-doc | 2020- | UMN (Chemistry Tree) |
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Publications
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Nathan Kochen N, Murray M, Zafari S, et al. (2025) Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery. Acs Chemical Neuroscience |
Braun A, Liao E, Vunnam N, et al. (2025) Multiplexed Dark FRET Biosensors: An accessible live-cell platform for target- and cell-specific monitoring of protein-protein interactions in 2D and 3D model systems. Research Square |
Kochen NN, Seaney D, Vasandani V, et al. (2024) Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study. Proteins |
Liao EE, Yang M, Nathan Kochen N, et al. (2023) Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology |
Braun AR, Kochen NN, Yuen SL, et al. (2023) Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. Asn Neuro. 15: 17590914231184086 |
Vunnam N, Yang M, Lo CH, et al. (2023) Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. Acs Bio & Med Chem Au. 3: 270-282 |
Pandey AK, Buchholz CR, Nathan Kochen N, et al. (2023) pH Effects Can Dominate Chemical Shift Perturbations in H,N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. Acs Chemical Neuroscience |
Ratnapriya S, Braun AR, Cervera Benet H, et al. (2022) Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. Acs Infectious Diseases |
Nathan Kochen N, Vasandani V, Seaney D, et al. (2022) Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth. Acs Chemical Neuroscience |
Braun AR, Liao EE, Horvath M, et al. (2021) Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52 |