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Jonathan N. Sachs

Affiliations: 
Biomedical Engineering University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Biomedical Engineering, General Biophysics
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"Jonathan Sachs"
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Parents

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Tom Woolf grad student Johns Hopkins (Neurotree)

Children

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Jason D. Perlmutter grad student 2011 UMN
Christopher C. Valley grad student 2012 UMN
Anthony R. Braun grad student 2014 UMN
Andrew Kyle Lewis grad student 2015 UMN (Chemistry Tree)
Mu Yang post-doc 2020- UMN (Chemistry Tree)

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Publications

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Liao EE, Yang M, Nathan Kochen N, et al. (2023) Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology. Molecular Neurobiology
Braun AR, Kochen NN, Yuen SL, et al. (2023) Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein. Asn Neuro. 15: 17590914231184086
Vunnam N, Yang M, Lo CH, et al. (2023) Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling. Acs Bio & Med Chem Au. 3: 270-282
Pandey AK, Buchholz CR, Nathan Kochen N, et al. (2023) pH Effects Can Dominate Chemical Shift Perturbations in H,N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions. Acs Chemical Neuroscience
Ratnapriya S, Braun AR, Cervera Benet H, et al. (2022) Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry. Acs Infectious Diseases
Nathan Kochen N, Vasandani V, Seaney D, et al. (2022) Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth. Acs Chemical Neuroscience
Braun AR, Liao EE, Horvath M, et al. (2021) Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52
Braun AR, Liao EE, Horvath M, et al. (2021) Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors. Npj Parkinson's Disease. 7: 52
Vunnam N, Szymonski S, Hirsova P, et al. (2020) Noncompetitive allosteric antagonism of death receptor 5 by a synthetic affibody ligand. Biochemistry
Lo CH, Huber EC, Sachs JN. (2020) Conformational states of TNFR1 as a molecular switch for receptor function. Protein Science : a Publication of the Protein Society
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