Santhosh Palani, Ph.D.

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Human Development, General Biophysics
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"Santhosh Palani"

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Casim A. Sarkar grad student 2010 Penn
 (Interplay of extrinsic and intrinsic cues in cell-fate decisions.)
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Publications

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Palani S, Sarkar CA. (2012) Transient noise amplification and gene expression synchronization in a bistable mammalian cell-fate switch. Cell Reports. 1: 215-24
Palani S, Sarkar CA. (2011) Synthetic conversion of a graded receptor signal into a tunable, reversible switch. Molecular Systems Biology. 7: 480
O'Shaughnessy EC, Palani S, Collins JJ, et al. (2011) Tunable signal processing in synthetic MAP kinase cascades. Cell. 144: 119-31
Palani S, Sarkar CA. (2009) Integrating extrinsic and intrinsic cues into a minimal model of lineage commitment for hematopoietic progenitors. Plos Computational Biology. 5: e1000518
Palani S, Sarkar CA. (2008) Positive receptor feedback during lineage commitment can generate ultrasensitivity to ligand and confer robustness to a bistable switch. Biophysical Journal. 95: 1575-89
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