Kristen J. Nicholson, Ph.D.

Affiliations: 
2013 Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biomedical Engineering, Biomechanics Biophysics, Neuroscience Biology
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"Kristen Nicholson"

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Beth A. Winkelstein grad student 2013 Penn
 (Defining the role of mechanical signals during nerve root compression in the development of sustained pain and neurophysiological correlates that develop in the injured tissue and spinal cord.)
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Publications

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Divi SN, Goyal DKC, Woods BI, et al. (2022) How Do Patients With Predominant Neck Pain Improve After Anterior Cervical Discectomy and Fusion for Cervical Radiculopathy? International Journal of Spine Surgery
Bullock GS, Menon G, Nicholson K, et al. (2020) Baseball pitching biomechanics in relation to pain, injury, and surgery: A systematic review. Journal of Science and Medicine in Sport
Raikin S, Shakked R, McDonald E, et al. (2018) Combined Popliteal Catheter with Single Injection Versus Continuous Infusion Saphenous Nerve Block Foot & Ankle Orthopaedics. 3: 2473011418S0000
Jarrell K, McDonald E, Shakked R, et al. (2017) Combined Popliteal Catheter With Single-Injection vs Continuous-Infusion Saphenous Nerve Block for Foot and Ankle Surgery. Foot & Ankle International. 1071100717744331
Nicholson KJ, Zhang S, Gilliland TM, et al. (2014) Riluzole effects on behavioral sensitivity and the development of axonal damage and spinal modifications that occur after painful nerve root compression. Journal of Neurosurgery. Spine. 20: 751-62
Nicholson KJ, Gilliland TM, Winkelstein BA. (2014) Upregulation of GLT-1 by treatment with ceftriaxone alleviates radicular pain by reducing spinal astrocyte activation and neuronal hyperexcitability. Journal of Neuroscience Research. 92: 116-29
Zhang S, Nicholson KJ, Smith JR, et al. (2013) The roles of mechanical compression and chemical irritation in regulating spinal neuronal signaling in painful cervical nerve root injury. Stapp Car Crash Journal. 57: 219-42
Smith JR, Syre PP, Oake SA, et al. (2013) Salmon and human thrombin differentially regulate radicular pain, glial-induced inflammation and spinal neuronal excitability through protease-activated receptor-1. Plos One. 8: e80006
Nicholson KJ, Gilliland TM, Winkelstein BA. (2013) Duration of nerve root compressive trauma modulates the subsequent thermal hyperalgesia and spinal expression of the glutamate transporter, GLT1 Asme 2013 Summer Bioengineering Conference, Sbc 2013. 1
Nicholson KJ, Guarino BB, Winkelstein BA. (2012) Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression Neuroscience. 209: 187-195
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