Randy J. Giedt, Ph.D.

Affiliations: 
2012 Biomedical Engineering Ohio State University, Columbus, Columbus, OH 
Area:
Biomedical Engineering
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"Randy Giedt"

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B Rita Alevriadou grad student 2012 Ohio State
 (Mitochondrial Network Dynamics in Vascular Endothelial Cells Exposed to Mechanochemical Stimuli: Experimental and Mathematical Analysis.)
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Publications

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Dubach JM, Kim E, Yang K, et al. (2016) Quantitating drug-target engagement in single cells in vitro and in vivo. Nature Chemical Biology
Giedt RJ, Fumene Feruglio P, Pathania D, et al. (2016) Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Scientific Reports. 6: 32985
Meimetis LG, Giedt RJ, Mikula H, et al. (2016) Fluorescent vinblastine probes for live cell imaging. Chemical Communications (Cambridge, England)
Giedt RJ, Fergulio PF, Pathania D, et al. (2016) Abstract 234: Mitochondrial morphology as a biomarker of cancer phenotype and drug response Cancer Research. 76: 234-234
Yang KS, Kohler RH, Landon M, et al. (2015) Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Scientific Reports. 5: 10129
Giedt RJ, Sprachman MM, Yang KS, et al. (2014) Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjugate Chemistry. 25: 2081-5
Meimetis LG, Carlson JC, Giedt RJ, et al. (2014) Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. Angewandte Chemie (International Ed. in English). 53: 7531-4
Giedt RJ, Koch PD, Weissleder R. (2013) Single cell analysis of drug distribution by intravital imaging. Plos One. 8: e60988
Giedt RJ, Pfeiffer DR, Matzavinos A, et al. (2012) Mitochondrial dynamics and motility inside living vascular endothelial cells: role of bioenergetics. Annals of Biomedical Engineering. 40: 1903-16
Giedt RJ, Yang C, Zweier JL, et al. (2012) Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radical Biology & Medicine. 52: 348-56
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