James R. Springstead, Ph.D.
Affiliations: | 2008 | University of California, Los Angeles, Los Angeles, CA |
Area:
Chemical EngineeringGoogle:
"James Springstead"Parents
Sign in to add mentor| Harold G. Monbouquette | grad student | 2008 | UCLA | |
| (Thermostable enzymes and membrane of Archaeoglobus fulgidus.) | ||||
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Publications
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| Di Gioia M, Spreafico R, Springstead JR, et al. (2019) Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nature Immunology |
| Zanoni I, Tan Y, Di Gioia M, et al. (2017) By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation. Immunity. 47: 697-709.e3 |
| Hogan NT, Whalen MB, Stolze LK, et al. (2017) Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells. Elife. 6 |
| Zanoni I, Tan Y, Di Gioia M, et al. (2016) An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells. Science (New York, N.Y.) |
| Emert B, Hasin-Brumshtein Y, Springstead JR, et al. (2014) HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms. Journal of Lipid Research. 55: 1678-1692 |
| Zhong W, Springstead JR, Al-Mubarak R, et al. (2013) An epoxyisoprostane is a major regulator of endothelial cell function. Journal of Medicinal Chemistry. 56: 8521-32 |
| Lee S, Birukov KG, Romanoski CE, et al. (2012) Role of phospholipid oxidation products in atherosclerosis. Circulation Research. 111: 778-99 |
| Springstead JR, Gugiu BG, Lee S, et al. (2012) Evidence for the importance of OxPAPC interaction with cysteines in regulating endothelial cell function. Journal of Lipid Research. 53: 1304-15 |
| Lim S, Springstead JR, Yu M, et al. (2009) Characterization of a key trifunctional enzyme for aromatic amino acid biosynthesis in Archaeoglobus fulgidus. Extremophiles : Life Under Extreme Conditions. 13: 191-8 |
| Lai D, Springstead JR, Monbouquette HG. (2008) Effect of growth temperature on ether lipid biochemistry in Archaeoglobus fulgidus. Extremophiles : Life Under Extreme Conditions. 12: 271-8 |