Jonathan T. Butcher, Ph.D.

Affiliations: 
2004 Georgia Institute of Technology, Atlanta, GA 
Area:
Biomedical Engineering, Mechanical Engineering, Molecular Biology, Cell Biology, General Biophysics, Medical Biophysics
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"Jonathan Butcher"

Parents

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Robert M. Nerem grad student 2004 Georgia Tech
 (The effects of steady laminar shear stress on aortic valve cell biology.)
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Publications

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Shih JY, Gee T, Scuderi G, et al. (2024) Biomechanical Remodeling of Aortic Valve Interstitial Cells During Calcified Lesion Formation In Vitro. Annals of Biomedical Engineering
Albert BJ, Butcher JT. (2023) Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells. Expert Opinion On Biological Therapy
Wang M, Lin BY, Sun S, et al. (2023) Shear and hydrostatic stress regulate fetal heart valve remodeling through YAP-mediated mechanotransduction. Elife. 12
Wu S, Li Y, Zhang C, et al. (2022) Tri-Layered and Gel-Like Nanofibrous Scaffolds with Anisotropic Features for Engineering Heart Valve Leaflets. Advanced Healthcare Materials. e2200053
Vaidya KA, Donnelly MP, Mahmut A, et al. (2022) Rac1 mediates Cadherin-11 induced cellular pathogenic processes in aortic valve calcification. Cardiovascular Pathology : the Official Journal of the Society For Cardiovascular Pathology. 107414
Farrar EJ, Hiriart E, Mahmut A, et al. (2021) OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification. Science Advances. 7: eabf7910
Ma N, Cheung DY, Butcher JT. (2021) Incorporating nanocrystalline cellulose into a multifunctional hydrogel for heart valve tissue engineering applications. Journal of Biomedical Materials Research. Part A
Driscoll K, Cruz AD, Butcher JT. (2021) Inflammatory and Biomechanical Drivers of Endothelial-Interstitial Interactions in Calcific Aortic Valve Disease. Circulation Research. 128: 1344-1370
Gee TW, Richards JM, Mahmut A, et al. (2021) Valve endothelial-interstitial interactions drive emergent complex calcific lesion formation in vitro. Biomaterials. 269: 120669
Wu S, Kumar V, Xiao P, et al. (2020) Age related extracellular matrix and interstitial cell phenotype in pulmonary valves. Scientific Reports. 10: 21338
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